共查询到20条相似文献,搜索用时 31 毫秒
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构建了纳米囊泡的原位凝胶系统. 以卵磷脂(PC)和胆固醇(CH)为纳米囊脂质材料, 按m(PC):m(CH)=3:1及m(脂质材料):m(药物)=5:1称取PC, CH和药物, 溶于无水乙醚作为有机相, 以质量分数为0.5%的吐温-80的磷酸盐(pH=7.4)缓冲液为水相(有机相与水相体积比为1.5:1), 采用薄膜分散-高压均质法制备了叶黄素纳米囊泡. 将普朗尼克F127(F127)和普朗尼克F68(F68)分散于纳米囊泡中水化, 制备了纳米囊泡原位凝胶系统. 以试管倒置法测定人工泪液和添加剂对F127-F68纳米囊泡原位凝胶系统胶凝温度的影响; 采用流变学研究了系统升温过程中溶胶-凝胶转变过程及上述辅料对该转变过程的影响; 分别以无膜溶蚀法和高效液相色谱(HPLC)法探讨了系统的体外溶蚀动力学和体外释药行为. 结果表明, 优化的纳米囊泡凝胶系统在25 ℃呈溶液态, 在眼部微环境下形成凝胶, 且药物释放及凝胶溶蚀均以恒定的速率进行, 为零级动力学特征. 相似文献
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采用等离子体发射光谱测定了马齿苋中微量元素的含量,并通过数理统计的方法对实验数据作了F、r检验及变异系数、可信度的计算。结果表明,中药的药理作用是活性成分和微量元素共同或协同作用的结果。 相似文献
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Noriaki Funasaki 《Journal of colloid and interface science》1982,90(2):551-553
The pressure-area curve in the liquidigas transition region can be used to confirm whether the equilibrium in the monolayer is attained. Three criteria for detecting the partial miscibility in monolayers are proposed. Collapse pressure data also are useful for detecting miscibility if appropriate attention is paid to the establishment of equilibrium. The general tendency of the changes of not consistent with that of most bulk liquid mixtures but with that of exceptional bulk alkane mixtures. For mixed monolayers of cholesterol with lecithins and trilaurin, Gershfeld's regular solution treatment yields positive Gex values, whereas Goodrich's theory yields negative ones. The former theory seems to be better referenced. 相似文献
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The adiabatic approximation in time-dependent density functional theory (TDDFT) yields reliable excitation spectra with great efficiency in many cases, but fundamentally fails for states of double-excitation character. We discuss how double-excitations are at the root of some of the most challenging problems for TDDFT today. We then present new results for (i) the calculation of autoionizing resonances in the helium atom, (ii) understanding the nature of the double excitations appearing in the quadratic response function, and (iii) retrieving double-excitations through a real-time semiclassical approach to correlation in a model quantum dot. 相似文献
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简要介绍2009年度国家自然科学基金情况,分析基金申请与学科发展存在问题;概述学科前沿与发展战略等;通报2010年项目指南。 相似文献
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浅论绿茶与乌龙茶氟含量对人体健康的影响 总被引:2,自引:0,他引:2
分别用重蒸水和自来水,通过蒸煮法和浸泡法制出不同浓度的绿茶液和乌龙茶液,对比测定研究茶液中氟含量,结果表明,茶液中的氟含量随茶叶浓度增加而增加,且乌龙茶高于绿茶,当茶叶浓度超过10.0g/L时,茶液中的氟含量即超过国家饮水卫生标准,提示人们饮用水茶液浓度在5.0g/L左右为宜。 相似文献
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Kohei Iwanaga 《Tetrahedron》2007,63(41):10127-10132
Trichloro[tris(2,5-dimethoxyphenyl)methyl]germane (1a), trichloro[tris(3-fluoro-6-methoxyphenyl)methyl]germane (1b), and trichloro[tris(2-methoxy-5-trifluoromethylphenyl)methyl]germane (1c) were synthesized. X-ray crystallographic analyses of 1a-c revealed their heptacoordinate geometries around the germanium atoms. The interatomic distances between the oxygen atoms and the central germanium atoms in the crystalline state were not significantly affected by change of functional groups on the benzene rings, while the optimized structures by theoretical calculations and Atoms in Molecules (AIM) analysis indicated linear relationship between the donating ability of functional groups and the O?Ge interatomic interactions. 相似文献
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建立了肉制品中脂肪酸的分析检测技术,通过分析脂肪酸含量、种类以及片段特征指纹图谱,实现了基于脂肪酸差异的肉制品中猪源性成分的鉴别。采用气相色谱法测定了大量肉制品,利用保留时间和质谱鉴定了36种脂肪酸成分,选取较为稳定的18种脂肪酸数据进行统计分析,确定不同油脂脂肪酸的差异,结合特征图谱,最终确定可用于鉴别猪源性成分的8种脂肪酸。该方法可用于确定肉制品中是否含有猪源性成分,方法简单、快速、成本低,辨别度较高,在猪源性成分鉴别中具有一定的应用前景。 相似文献
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近年国内固相萃取-色谱分析的进展 总被引:7,自引:0,他引:7
对近两年国内各个领域的学者在使用固相萃取做样品前处理的色谱分析方面的研究和应用作了综述, 这一综述包括10个部分: 1. 国内近两年有关固相萃取的综述报告;2. 固相萃取-色谱分析在水质分析中的应用;3. 固相萃取-色谱分析在奶制品和肉类食品分析中的应用;4. 固相萃取-色谱用于蔬菜和水果中有害物质分析的应用;5. 固相萃取-色谱用于粮食和其他食品中有害物质分析的应用;6. 固相萃取-色谱在血药浓度、体液及组织中有害物质分析中的应用;7. 固相萃取-色谱在药物分析中的应用;8. 固相萃取-色谱在其他使用色谱分析中的应用;9. 基质固相分散在色谱分析中的应用;10. 分子印迹SPE在样品前处理中的应用. 相似文献
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扇贝肉营养成分分析研究 总被引:7,自引:0,他引:7
应用氨基酸自动分析仪分析了扇贝肉中的氨基酸含量,用原子吸收光谱法测定了其中钙、镁、锌,硒等元素的含量,为扇贝的开发研究提供了营养学依据。 相似文献
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综述了新型二维碳材料石墨烯(Graphene)在光催化研究中的主要进展.重点讨论了以分解水制氢的研究体系发展和基于石墨烯为电子受体及传递介质的新型、高效的光敏化和半导体光催化制氢体系(催化剂)的构建,也对石墨烯在促进光诱导电荷分离和迁移过程中的作用机制进行了讨论. 相似文献
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Study on Retention in Liquid Chromatography 总被引:2,自引:0,他引:2
Kiyokatsu JINNO 《色谱》2002,20(1):21-29
After joining the faculty at Toyohashi University of Technology (TUT) in 1978, the author has found two areas in separation sciences where microcolumn liquid chromatography (micro LC) can be beneficial One is the hyphenated techniques between many spectroscopic methods such as mass (MS), infrared (FT IR) and atomic emission (ICP), and micro LC The other one is rather difficult, but basic and theoretical approach which deals with retention mechanism in LC. 相似文献
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佛手瓜微量元素含量的测定 总被引:6,自引:0,他引:6
用电感耦合等离子体发射光谱仪(ICP-AES)测定了湛江人工栽培佛手瓜中微量元素的含量,发现其钙、镁、铁、锌等元素的含量都比较丰富,并讨论了这些有益元素与人体健康的关系。 相似文献
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Lee SH Son JK Jeong BS Jeong TC Chang HW Lee ES Jahng Y 《Molecules (Basel, Switzerland)》2008,13(2):272-300
Rutaecarpine is an indolopyridoquinazolinone alkaloid isolated from Evodia rutaecarpa and related herbs, which has shown a variety of intriguing biological properties such as anti-thrombotic, anticancer, anti-inflammatory and analgesic, anti-obesity and thermoregulatory, vasorelaxing activity, as well as effects on the cardiovascular and endocrine systems. Recent progress in the studies on the isolation, synthesis, structure-activity relationship studies, biological activities and metabolism of rutaecarpine are reviewed. 相似文献