应用激光解吸质谱和十二烷基硫酸钠—聚丙烯酰胺凝胶电泳分析蛇毒？…

应用基质辅助激光解吸电离飞行时间质谱（ＭＡＬＤＩ－ＴＯＦ－ＭＳ）和ＳＤＳ－聚丙烯酰胺凝胶电流对吉林省两地市的同种白眉蝮蛇蛇毒中具有抗栓塞药效的精氨酸酯酶进行了分析了分析和比较。ＭＡＬＤＩ－ＴＯＦ－ＭＳ法具有快速、准确度高、灵敏度高的优点,两种方法结合,互为补充,取得了令人满意的结果。ＭＡＬＤＩ－ＴＯＦ－ＭＳ完全可以直接用作蛇毒成分分离过程中重要的研究手段。     

ONE－POT STEREOSELECTIVE SYNTHESIS OF FUSED RING SYSTEMS CONSISTING OF ISOXAZOLINE AND TETRAHYDRO－FURAN，－THIOPHENE，OR－PYRROLE VIA INTRAMOLECULAR CYCLOADDITION OF SILYL NITRONATES DERIVED FROM α－NITROALKENES

ＯＮＥ－ＰＯＴＳＴＥＲＥＯＳＥＬＥＣＴＩＶＥＳＹＮＴＨＥＳＩＳＯＦＦＵＳＥＤＲＩＮＧＳＹＳＴＥＭＳＣＯＮＳＩＳＴＩＮＧＯＦＩＳＯＸＡＺＯＬＩＮＥＡＮＤＴＥＴＲＡＨＹＤＲＯ－ＦＵＲＡＮ，－ＴＨＩＯＰＨＥＮＥ，ＯＲ－ＰＹＲＲＯＬＥＶＩＡＩＮＴＲＡＭＯＬＥ...     

α-AMIDOALKYLATION VIA SULFONES:TOWARDS THE SYNTHESIS OF ANT VENOM ALKALOIDS

α－ＡＭＩＤＯＡＬＫＹＬＡＴＩＯＮ　ＶＩＡ　ＳＵＬＦＯＮＥＳ：ＴＯＷＡＲＤＳ　ＴＨＥ　ＳＹＮＴＨＥＳＩＳ　ＯＦ　ＡＮＴ　ＶＥＮＯＭ　ＡＬＫＡＬＯＩＤＳα－ＡＭＩＤＯＡＬＫＹＬＡＴＩＯＮＶＩＡＳＵＬＦＯＮＥＳ：ＴＯＷＡＲＤＳＴＨＥＳＹＮＴＨＥＳＩＳＯＦ...     

INDIRECT THERMO－OPTICAL DETECTION FOR CAPILLARY ELECTROPHORESIS SEPARATION OF AMINO ACIDS

ＩＮＤＩＲＥＣＴ　ＴＨＥＲＭＯ－ＯＰＴＩＣＡＬ　ＤＥＴＥＣＴＩＯＮ　ＦＯＲ　ＣＡＰＩＬＬＡＲＹ　ＥＬＥＣＴＲＯＰＨＯＲＥＳＩＳ　ＳＥＰＡＲＡＴＩＯＮ　ＯＦ　ＡＭＩＮＯ　ＡＣＩＤＳＩＮＤＩＲＥＣＴＴＨＥＲＭＯ－ＯＰＴＩＣＡＬＤＥＴＥＣＴＩＯＮＦＯＲＣＡ...     

PARAMAGNETIC AND DIAMAGNETIC DICOPPER（Ⅱ） COMPLEXES WITH DI－SCHIFF BASE DERIVED FROM 2－HYDROXY－1－NAPHTHALDEHYDE AND1，3－DIANINO－2－PROPANOL

ＰＡＲＡＭＡＧＮＥＴＩＣＡＮＤＤＩＡＭＡＧＮＥＴＩＣＤＩＣＯＰＰＥＲ（Ⅱ）ＣＯＭＰＬＥＸＥＳＷＩＴＨＤＩ－ＳＣＨＩＦＦＢＡＳＥＤＥＲＩＶＥＤＦＲＯＭ２－ＨＹＤＲＯＸＹ－１－ＮＡＰＨＴＨＡＬＤＥＨＹＤＥＡＮＤ１，３－ＤＩＡＮＩＮＯ－２－ＰＲＯＰＡＮＯＬ...     

ZEOLITE－CATALYZED FRIEDEL－CRAFTS ACYLATION OF AROMATICS：I》．SYNTHESIS OF 4－ACYL ANISOLE WITH A HY CATALYST

ＺＥＯＬＩＴＥ－ＣＡＴＡＬＹＺＥＤＦＲＩＥＤＥＬ－ＣＲＡＦＴＳＡＣＹＬＡＴＩＯＮＯＦＡＲＯＭＡＴＩＣＳ：Ｉ．ＳＹＮＴＨＥＳＩＳＯＦ４－ＡＣＹＬＡＮＩＳＯＬＥＷＩＴＨＡＨＹＣＡＴＡＬＹＳＴ￥ＱｉＬｏｎｇＷＡＮＧ；ＹｕＤａｏＭＡ；ＸｉｎｇＤｏｎｇＪＩ；Ｈ...     

A NOVEL CYCLODIMERIZATION OF α，β－ UNSATURATED KETONES PROMOTED BY LOW－VALENT TITANIUM

Ａ ＮＯＶＥＬ ＣＹＣＬＯＤＩＭＥＲＩＺＡＴＩＯＮ ＯＦ α，β－ＵＮＳＡＴＵＲＡＴＥＤ ＫＥＴＯＮＥＳ ＰＲＯＭＯＴＥＤ ＢＹ ＬＯＷ－ＶＡＬＥＮＴ ＴＩＴＡＮＩＵＭ￥ＬｏｎｇＨｕＺＨＯＵ；ＧｕｉＹｕａｎＤＡＩ；ＤａＱｉｎｇＳＨＩ（Ｄｅｐａｒｔｍｅ...     

PRACTICAL METHOD FOR SYNTHESIS OF NEW GLYCOLIPIDS N－［4（DIALKYL－L－GLUTAMATECARBONYLETHYLCARBO－NYLAMINO）BUTYL］LACTOBIONAMIDES

ＰＲＡＣＴＩＣＡＬＭＥＴＨＯＤＦＯＲＳＹＮＴＨＥＳＩＳＯＦＮＥＷＧＬＹＣＯＬＩＰＩＤＳＮ－［４（ＤＩＡＬＫＹＬ－Ｌ－ＧＬＵＴＡＭＡＴＥＣＡＲＢＯＮＹＬＥＴＨＹＬＣＡＲＢＯ－ＮＹＬＡＭＩＮＯ）ＢＵＴＹＬ］ＬＡＣＴＯＢＩＯＮＡＭＩＤＥＳ￥ＺｈｏｎｇＺｈｉ...     

SYNTHESIS OF POLYSUBSTITUTED AROMATIC COMPOUNDS 3.THE DIELS-ALDER REACTION OF PHENYLSELENO SUBSTITUTED DIENES WITH DIMETHYL ACETYLENEDICARBOXYLATE

ＳＹＮＴＨＥＳＩＳ　ＯＦ　ＰＯＬＹＳＵＢＳＴＩＴＵＴＥＤ　ＡＲＯＭＡＴＩＣ　ＣＯＭＰＯＵＮＤＳ　３．ＴＨＥ　ＤＩＥＬＳ－ＡＬＤＥＲ　ＲＥＡＣＴＩＯＮ　ＯＦ　ＰＨＥＮＹＬＳＥＬＥＮＯ　ＳＵＢＳＴＩＴＵＴＥＤ　ＤＩＥＮＥＳ　ＷＩＴＨ　ＤＩＭＥＴＨＹＬ　Ａ...     

OFF－LINE TWO－DIMENSIONAL GAS CHROMATOGRAPHY－MASS SPECTROMETRY FOR ANALYSIS OF ASSENTAL OIL OF MEDICINAL HERB：USE OF ABSORPTION TRAP AS INTERFACE

ＯＦＦ－ＬＩＮＥＴＷＯ－ＤＩＭＥＮＳＩＯＮＡＬＧＡＳＣＨＲＯＭＡＴＯＧＲＡＰＨＹ－ＭＡＳＳＳＰＥＣＴＲＯＭＥＴＲＹＦＯＲＡＮＡＬＹＳＩＳＯＦＡＳＳＥＮＴＡＬＯＩＬＯＦＭＥＤＩＣＩＮＡＬＨＥＲＢ：ＵＳＥＯＦＡＢＳＯＲＰＴＩＯＮＴＲＡＰＡＳＩＮＴＥＲＦＡ...     

聚芳醚砜环状低聚物的基质辅助激光解吸电离质谱分析

采用基质辅助激光解吸电离飞行时间质谱技术分别对两种合成的聚芳醚砜环状低聚物进行了分析研究，并讨论了低聚物中不同聚合度离子组份的分布规律。     

聚芳醚酮环状低聚物的基质辅助激光解吸电离质谱表征

采用基质辅助激光解吸电离飞行时间质谱(MALDI-TOF-MS)技术分别对2种合成的聚芳醚酮环状低聚物进行了分析研究 ,并讨论了低聚物中不同聚合度离子组分的分布规律。实验结果表明MALDI-TOF-MS是分析环状低聚物直观、准确、快速的分析工具。     

Analysis of polyaniline oligomers by laser desorption ionization and solventless MALDI

While direct laser desorption ionization of soluble polyaniline dried onto metal sample plates results in mass spectra that are similar to previously shown electrospray ionization data of similar samples, laser desorption of unsolubilized solid polyaniline results in major fragmentation of the phenyl rings. Solventless MALDI, a recently developed technique for insoluble or slightly soluble species, involves the use of only solid analyte and matrix during sample preparation. Solventless MALDI of solid polyaniline results in mass spectra that are similar to the direct laser desorption ionization spectra of the soluble oligomers with some larger molecular weight oligomers also being detected. Based on the matrix used, different series of polyaniline with dissimilar end groups are detected. The matrix also affects the percentages of benzenoid and quinoid units in the oligomers. Thus, solventless MALDI appears to be a promising new technique for the mass spectrometric analysis of low solubility, but industrially important, polyanilines.     

应用激光解吸电离飞行时间质谱法研究芳香聚硫醚醚砜环状低聚物

应用激光解吸电离飞行时间质谱法对芳香环状聚硫醚醚砜低聚物结构进行了分析,比较了四种不同基质对环状物结构分析结果的影响,发现1,8,9-蒽三酚为此类芳香环状低聚物的有效基质。探讨了金属阳离子对此类芳香环状低聚物的影响,认为三氟乙酸银是此种芳香环状低聚物的有效阳离子剂。     

A NEW APPROACH TO ELECTROACTIVE POLYMERS VIA WELL-DEFINED OLIGOMERRS WITH FURTHER POLYMERIZABLE END-GROUPS

Among the inherent drawbacks of conducting polymers are the limited processibility, uneven polydispersity inmolecular weigh and the existence of structure defects, which become the obstacles for many electronic, optical andbiological applications that demand the materials to have well-defined structures and high chemical purity. To solve theseproblems, our research in the last decade or so has focused on the synthesis of electroactive oligomers of well-definedstructures, controllable molecular weighs, narrow or uniform polydispersity. We have developed a general strategy for thesynthesis of such oligomers based on the theory of non-classical or reactivation chain polymerization. The aniline oligomerswith minimum 4 nitrogen atoms and 3 phenylene rings exhibit similar characteristic redox behavior and electroactivity aspolyaniline. Electronic conductivity of the oligomers of 7 or 8 aniline units approaches that of polyaniline. Solubility of theoligomers is much improved over that of conventional polyaniline. Various functional groups can be introduced into theoligomers either by proper selection of starting materials or by post-synthesis modifications via common organic reactions.The functionalized oligomers undergo further polymerizations to afford a variety of new electroactive materials, includingpolyamides, polyimides, polyureas, polyurethanes, polyacrylamides and epoxy polymers. Numerous potential applications,particularly as anticorrosion materials, are discussed for the oligomers and their polymeric derivatives.     

芳香环状聚酯二聚体的结构表征

通过基质辅助激光解析电离飞行时间质谱以及核磁共振技术对芳香环状聚酯二聚体的结构进行了表征.质谱分析结果发现除了目标化合物的质子化分子离子峰外,未出现更多的碎片峰,而核磁共振结果对芳香环状齐聚物的氢以及碳的位置给予了确认.从而为芳香环状齐聚物的结构分析提供了一种新的分析方法.     

基质辅助激光解吸电离-飞行时间质谱表征6氟双酚A芳香环状聚醚酮(砜)

应用基质辅助激光解吸电离飞行时间质谱,在不同阳离子剂的存在下,对6氟双酚A聚芳醚酮(砜)环状低聚物的结构进行了确认,研究了环状化合物对金属离子的选择性及激光质谱表征含氟环状低聚物的适宜条件.     

原位核磁共振技术考察L-缬氨酸导引下合成花状纳米结构聚苯胺形成机理的研究

利用~1H-NMR原位追踪在L-缬氨酸存在下合成花状纳米聚苯胺的形成过程中发现此结构的形成经历3个阶段:首先在苯胺与缬氨酸构成的类胶束结构内聚合成吩嗪类寡聚物;其次通过p-p重叠作用及胶束融合过程成为片状聚集体;最终通过与缬氨酸形成氢键组装成花瓣状纳米聚苯胺.通过改变反应条件,对比形成过程中核磁共振图谱及产物形貌的变化发现花状纳米聚苯胺的形成有如下特征:反应初期L-缬氨酸作为缓冲试剂可以避免苯胺的骤然质子化,有利于生成具有吩嗪结构的寡聚物;反应前苯胺单体与缬氨酸形成稳定的反应环境保证寡聚物始终在其内聚集生长,有效避免了外部环境的影响.     

几种导电聚合物热分解行为的直接裂解质谱研究

本文用直接裂解低能电子轰击电离和化学电离质谱(DPMS)等方法研究了聚对苯硫醚(PPS).聚噻吩(PT)和聚苯胺(PAn)的热分解行为和某些结构性质, 能提供多至7个链节重复单元的裂解碎片.结果表明: 几种聚合物的热分解均以自由基方式降解,PPS形成环状和线状齐聚物,PT和PAn只能形成线状齐聚物.     

芳香环状低聚体的结构表征

综述了芳香环状低聚体结构表征的发展过程及最新进展,以高效液相色谱、快原子（离子）轰击质谱、激光质谱、电喷雾质谱为主结合其他辅助方法分别做以介绍并比较了各种表征方法的特点及应用范围。