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将化学教学与学生生活相融合,通过设计生活中的探究学习任务,使用贴吧作为学生自主学习的交流平台,促进学生对生活和化学的了解,促进学生课余的自主学习。并通过实例具体叙述了生活中的探究学习任务的设计策略和网络交流平台的使用策略。 相似文献
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践行建构主义的理念,通过协作学习和自主学习,激发学生学习的内在动力,充分调动了学生的探究积极性,培养学生的创新精神和实践能力,并促进了合作学习以及学生的自我评价。 相似文献
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探究学习是提高学生科学探究能力的重要途径。探究学习活动中要突出学生自主活动,落实学生的主体性;通过合作学习,培育学生的合作精神;重视教师指导作用,发展学生探究能力;坚持科学评价,促进学生全面发展。 相似文献
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探索无线应答系统在有机化学课堂教学中的应用。这种课堂教学模式能提高学生对有机化学课堂教学的兴趣,促进学生主动学习,提高教师的工作效率;还可以用于了解学生的学习状况,跟踪学习进程,提高有机化学课堂教学质量。 相似文献
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研究性学习中学生的学习行为分析 总被引:1,自引:0,他引:1
教学活动设计的核心问题是引导学生的学习行为,从而促进学生心理的发展。对学生的学习行为的分析可以了解学生在研究过程中对自己知识框架的构建和整合过程,以及对研究性学习目的所达到的程度。本文从学生的特征、学习风格、研究小组的分工合作、学生信息来源等方面对研究性学习中学生学习行为进行了粗略的分析。 相似文献
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在实践的过程中逐步积累并形成的学生与学生之间的互问、互查和互测的教学方法,使学生在自主选题、小组合作和参与评价的过程中,以多种形式优化学生学习过程中知识结构的形成,引导学生主动反思,改变以往被动接受、被动练习的学习状态,提高学习的主动性,促进教学方法和学习方式的改变。 相似文献
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Electrochemistry is one of the most advanced techniques for monitoring neurochemical activities in the living brain because electrochemical approaches bear the advantageous features of high spatial and temporal resolutions, which facilitate its tremendous potential in investigating the highly spatially heterogeneous brain system and the fast dynamics of neurochemical activities. On the other hand, since brain is the most complicated organ in the sense of its numerous kinds of neurochemical species, high selectivity is always required for any analytical methods that approach the brain. In this review, we will discuss various electrochemical methodologies to achieve selective detection of neurochemicals in mammalian brain and the strategies developed mainly by our group towards selective monitoring of both electrochemically active and inactive neurochemicals. At the end, we will discuss possible solutions towards brain mapping of neurochemical species and combination of neurochemical detection strategy with electrophysiology as the direction of future development of electroanalysis in living brain. 相似文献
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Reactions in droplets in microfluidic channels 总被引:5,自引:0,他引:5
Fundamental and applied research in chemistry and biology benefits from opportunities provided by droplet-based microfluidic systems. These systems enable the miniaturization of reactions by compartmentalizing reactions in droplets of femoliter to microliter volumes. Compartmentalization in droplets provides rapid mixing of reagents, control of the timing of reactions on timescales from milliseconds to months, control of interfacial properties, and the ability to synthesize and transport solid reagents and products. Droplet-based microfluidics can help to enhance and accelerate chemical and biochemical screening, protein crystallization, enzymatic kinetics, and assays. Moreover, the control provided by droplets in microfluidic devices can lead to new scientific methods and insights. 相似文献
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The toxicity of inorganic trivalent arsenic for living organisms is reduced by in vivo methylation of the element. In man, this biotransformation leads to the synthesis of monomethylarsonic (MMA) and dimethylarsinic (DMA) acids, which are efficiently eliminated in urine along with the unchanged form (Asi). In order to document the methylation process in humans, the kinetics of Asi, MMA and DMA elimination were studied in volunteers given a single dose of one of these three arsenicals or repeated doses of Asi. The arsenic methylation efficiency was also assessed in subjects acutely intoxicated with arsenic trioxide (As2O3) and in patients with liver diseases. Several observations in humans can be explained by the properties of the enzymic systems involved in the methylation process which we have characterized in vitro and in vivo in rats as follows: (1) production of Asi metabolites is catalyzed by an enzymic system whose activity is highest in liver cytosol; (2) different enzymic activities, using the same methyl group donor (S-adenosylmethionine), lead to the production of mono- and di-methylated derivatives which are excreted in urine as MMA and DMA; (3) dimethylating activity is highly sensitive to inhibition by excess of inorganic arsenic; (4) reduced glutathione concentration in liver moderates the arsenic methylation process through several mechanisms, e.g. stimulation of the first methylation reaction leading to MMA, facilitation of Asi uptake by hepatocytes, stimulation of the biliary excretion of the element, reduction of pentavalent forms before methylation, and protection of a reducing environment in the cells necessary to maintain the activity of the enzymic systems. 相似文献
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