共查询到20条相似文献,搜索用时 34 毫秒
1.
Wei‐Lie Xiao Ying‐Li Wu Shan‐Zhai Shang Fei He Xiao Luo Guang‐Yu Yang Jian‐Xin Pu Guo‐Qiang Chen Han‐Dong Sun 《Helvetica chimica acta》2010,93(10):1975-1982
Four new highly oxygenated nortriterpenoids, lancifodilactones O–R ( 1 – 4 ), together with six known ones, i.e., 5 – 10 , were isolated from the leaves and stems of Schisandra lancifolia. Their structures were elucidated by spectroscopic analyses, including 1D‐ and 2D‐NMR experiments and mass spectrometry. Compounds 1 – 3 were evaluated for their cytotoxicity against NB4, A549, SHSY5Y, PC‐3, and MCF‐7 cell lines. No compounds exhibited significant cytotoxicity, the IC50 values being above 50 μM . 相似文献
2.
Yu‐Hong Zhou Yong Jiang Hai‐Ming Shi Yu‐Ping Chen Peng‐Fei Tu 《Helvetica chimica acta》2008,91(5):897-903
Five new xanthenone O‐glycosides, sibiricaxanthone C ( 1 ), sibiricaxanthone D ( 2 ), sibiricaxanthone E ( 3 ), sibiricaxanthone F ( 4 ), and sibiricaxanthone G ( 5 ) were isolated from the roots of Polygala sibirica L., together with the six known xanthenone glycosides 6 – 11 . The structures of new compounds were elucidated on the basis of spectral data and acid hydrolysis. 相似文献
3.
Yuan‐Dan Li Zhao‐Yuan Wu Hong‐Mei Li Hai‐Zhou Li Rong‐Tao Li 《Helvetica chimica acta》2013,96(3):424-430
Three new iridoids, jatamanins N–P ( 1 – 3 ), along with the seven known iridiods 4 – 10 , were isolated from the roots of Valeriana jatamansi. Compound 1 is an unusual iridoid bearing two epoxy bridges between C(3) and C(6) and between C(1) and C(10), forming a unique cage‐like rigid skeleton. The structures of the new compounds were assigned on the basis of spectroscopic methods. 相似文献
4.
Ya‐Qi Wang Li Bao Xiao‐Li Yang Huan‐Qin Dai Hui Guo Xin‐Sheng Yao Li‐Xin Zhang Hong‐Wei Liu 《Helvetica chimica acta》2012,95(2):261-267
Flamvelutpenoids A–D ( 1 – 4 ), four new cuparene‐type sesquiterpenes, were isolated from the solid culture of Flammulina velutipes. Their structures were elucidated by NMR experiments. The absolute configurations of 1 and 2 were assigned via the circular dichroism data of the [Rh2(OCOCF3)4] complex, whereas that of C(3) of 3 was determined by applying the octant rule for the α,β‐unsaturated ketone moiety. Compounds 1 – 4 showed weak antibacterial activity against Escherichia coli, Bacillus subtilis, and methicillin‐resistant Staphylococcus aureus with MIC values larger than 100 μM . 相似文献
5.
Guang‐Yu Yang Wei‐Lie Xiao Ying Chang Rui‐Rui Wang Jian‐Xin Pu Xue‐Mei Gao Chun Lei Yang Lu Yong‐Tang Zheng Han‐Dong Sun 《Helvetica chimica acta》2008,91(10):1871-1878
Three new highly oxygenated nortriterpenoids, wilsonianadilactones A–C ( 1 – 3 ), together with twelve known ones, i.e., 4 – 15 , were isolated from the leaves and stems of Schisandra wilsoniana. Their structures were established by means of extensive analysis of spectroscopic data, and compound 1 was further confirmed by X‐ray crystallographic diffraction. Compounds 1 – 3 showed weak anti‐HIV‐1 activity with EC50 values of 23.5, 55.5, and 66.4 μg/ml, respectively. 相似文献
6.
Yu‐Zhi Zhou Huan Chen Li Qiao Xuan Lu Hui‐Ming Hua Yue‐Hu Pei 《Helvetica chimica acta》2008,91(7):1277-1285
Five new aromatic glycosides, 1 – 5 , named as carthamosides B4–B8, together with three known compounds, 4′‐(hydroxyphenacyl)‐β‐D ‐glucopyranoside ( 6 ), benzyl‐O‐α‐L ‐rhamnopyranosyl‐(1→6)‐β‐D ‐glucopyranoside ( 7 ), and 4‐(methoxybenzyl)‐O‐β‐D ‐glucopyranoside ( 8 ), have been isolated from the air‐dried flower of Carthamus tinctorius. Their structures were identified on the basis of chemical and spectroscopic methods. 相似文献
7.
Seven novel polyketides, namely, 1‐(xylarenone A)xylariate A ( 1 ), xylarioic acid B ( 2 ), xylariolide A ( 3 ), xylariolide B ( 4 ), xylariolide C ( 5 ), methyl xylariate C ( 6 ), and xylariolide D ( 7 ), together with the known one taiwapyrone ( 8 ), were isolated from the endophytic fungal strain Xylaria sp. NCY2 of Torreya jackii Chun . Their structures were elucidated by spectroscopic analyses, including 1D‐ and 2D‐NMR experiments, and on the basis of HR‐Q‐TOF mass spectrometry. Antitumor and antibacterial assays of compounds 1 – 8 were carried out, which show moderate activities. 相似文献
8.
Ya‐Ching Shen Yun‐Sheng Lin Shaw‐Man Hsu Ashraf Taha Khalil Shih‐Sheng Wang Ching‐Te Chien Yao‐Haur Kuo Chang‐Hung Chou 《Helvetica chimica acta》2007,90(7):1319-1329
The phytochemical investigation of the more polar fractions from the leaves and twigs of Taxus sumatrana (Taxaceae) afforded five new taxane diterpene esters, tasumatrols P–T ( 1 – 5 ) possessing an 11(15→1),11(10→9)‐diabeotaxane skeleton. Compounds 1, 4 , and 5 contain an α‐hydroxy group at C(14), while 3 has no OH group at either C(13) or C(14). Compound 2 is a natural 4,5‐acetonide derivative, while 4 has an unusual spiro‐connected 2‐hydroxy‐2‐phenyl‐1,3‐dioxolane ring. Ten known taxoids, were also isolated in the course of the chromatographic fractionation. Five additional new O‐acetyl derivatives 3a, 4a, 4b, 5a , and 5b were prepared from the taxanes 3 – 5 . The structures of all new compounds were established on the basis of their spectroscopic analyses. Compound 1 showed mild cytotoxic activity against human Hela and Daoy tumor cells. 相似文献
9.
Zu‐Shang Su Sheng‐Ping Yang Sheng Zhang Lei Dong Jian‐Min Yue 《Helvetica chimica acta》2011,94(8):1515-1526
Eleven new limonoids, meliarachins A–K ( 1 – 11 , resp.), together with five known ones, were isolated from the twigs and leaves of Melia azedarach. The structures of the new compounds were elucidated on the basis of spectroscopic analysis. Compounds 4 and 8 exhibited moderate antibacterial activities against Gram‐positive bacteria. 相似文献
10.
Li‐Ning Wang Dong‐Xiao Guo Shu‐Qi Wang Chang‐Sheng Wu Mujeeb Ur Rehman Hong‐Xiang Lou 《Helvetica chimica acta》2011,94(6):1146-1152
Four new phenolic glycosides, named rebouosides A–D ( 1 – 4 , resp.), along with three known ones 2‐(3,4‐dihydroxyphenyl)ethyl 2‐O‐α‐L ‐rhamnopyranosyl‐β‐D ‐allopyranoside ( 5 ), 2‐(3,4‐dihydroxyphenyl)ethyl β‐D ‐allopyranoside ( 6 ), 2‐(3,4‐dihydroxyphenyl)ethyl β‐D ‐glucopyranoside ( 7 ), and a nucleoside, inosine ( 8 ), were isolated from Chinese liverwort Reboulia hemisphaerica. Their structures were elucidated by acidic hydrolysis and extensive spectroscopic methods, including 2D‐NMR techniques. 相似文献
11.
Yang Yu Hao Gao Yi Dai Ying Wang He‐Ru Chen Xin‐Sheng Yao 《Helvetica chimica acta》2010,93(4):763-771
Eight new monoterpenoids, jasminoside J ( 1 ), jasminoside K ( 2 ), 6′‐O‐trans‐sinapoyljasminoside B ( 3 ), 6′‐O‐trans‐sinapoyljasminoside L ( 4 ), jasminosides M–P ( 5 – 8 ), together with three known analogues, jasminoside C ( 9 ), jasminol E ( 10 ), and sacranoside B ( 11 ), were isolated from the fruit of Gardenia jasminoides Ellis (Rubiaceae). Their structures were elucidated by spectral and chemical methods. 相似文献
12.
Three new chromenone glucosides acylated with monoterpene acids, eucamaldusides A ( 1 ), B ( 2 ), and C ( 3 ), were isolated from the leaves of Eucalyptus camaldulensis var. obtusa, together with the five known compounds ursolic acid lactone, obtusilin, β‐sitosterol glucoside, 4‐hydroxybenzoic acid, and cypellocarpin C. The structures of the new compounds were established by exhaustive 1D‐ and 2D‐NMR spectroscopic studies. Their configuration was determined by measuring the [α]D of the known methyl esters of the monoterpene acids obtained by methanolysis of 1 – 3 . 相似文献
13.
Xing‐Ping Zheng Qiong‐Fang Cui Jing‐Feng Zhao Li‐Juan Yang Hong‐Bin Zhang Xiao‐Dong Yang Liang Li 《Helvetica chimica acta》2014,97(12):1638-1643
Three new phthalides, gnaphalides A–C ( 1 – 3 , resp.), together with three known phthalides, were isolated from the aerial part of Gnaphalium adnatum. The structures of the new compounds were elucidated as 6‐(1,1‐dimethylprop‐2‐en‐1‐yl)‐5,7‐dihydroxy‐2‐benzofuran‐1(3H)‐one ( 1 ), 5‐hydroxy‐7‐[(2‐hydroxy‐3‐methylbut‐3‐en‐1‐yl)oxy]‐2‐benzofuran‐1(3H)‐one ( 2 ), and 1,3‐dihydro‐7‐[(3‐methylbut‐2‐en‐1‐yl)oxy]‐1‐oxo‐2‐benzofuran‐5‐yl β‐D ‐glucopyranoside ( 3 ) on the basis of spectral analyses. The structure of 1 was also confirmed by X‐ray crystallographic analysis. The three known phthalides, identified as 5,7‐dihydroxyisobenzofuran‐1(3H)‐one ( 4 ), anaphatol ( 5 ), and 7‐O‐(β‐glucopyranosyl)‐5‐hydroxyisobenzofuran‐1(3H)‐one ( 6 ), were isolated from the genus Gnaphalium for the first time. 相似文献
14.
Masafumi Kikuchi Rie Kakuda Yasunori Yaoita Masao Kikuchi 《Helvetica chimica acta》2008,91(7):1236-1243
Four new secoiridoid glucosides, swertiajaposides C–F ( 1 – 4 , resp.), were isolated from the whole plant of Swertia japonica Makino together with two known compounds, 8‐hydroxy‐10‐hydrosweroside ( 5 ) and senburiside IV ( 6 ). The structures of 1 – 4 were elucidated on the basis of spectroscopic, chemical, and physicochemical evidence. 相似文献
15.
Three new monoterpenoid indole alkaloids, vinmajorines C–E ( 1 – 3 ), along with 18 known analogues ( 4 – 21 ), were isolated from the whole plants of Vinca major. The new structures were elucidated as (5α,15β,16R,17α,19β,20α,21β)‐10,17‐dimethoxy‐21‐methyl‐18‐oxa‐5,16‐cycloyohimban‐19‐ol ( 1 ), (5α,15β,16R,17α,20α,21β)‐10‐methoxy‐21‐methyl‐18‐oxa‐5,16‐cycloyohimban‐17‐ol ( 2 ), and (5α,15β,16R,17α,20α,21β)‐10‐methoxy‐21‐methyl‐18‐oxa‐5,16‐cycloyohimban‐17‐yl acetate ( 3 ), respectively, by extensive NMR and MS analysis and comparison with known compounds. Compounds 1 – 3 were evaluated for their cytotoxic activities against five human cancer cell lines, compounds 1 and 3 showing moderate cytotoxic activities. 相似文献
16.
Yong Shen Ai‐Xue Zuo Zhi‐Yong Jiang Xue‐Mei Zhang Hong‐Ling Wang Ji‐Jun Chen 《Helvetica chimica acta》2010,93(3):482-489
Five new C19‐diterpenoid alkaloids, named hemsleyaconitines A–E ( 1 – 5 , resp.), were isolated from Aconitum hemsleyanum Pritz. By UV, IR, MS, 1D‐ and 2D‐NMR analyses, their structures were elucidated as 18‐dehydroxygeniculatine D ( 1 ), 6‐hydroxy‐14‐O‐veratroylneoline ( 2 ), 14‐O‐acetyl‐8‐ethoxysachaconitine ( 3 ), 18‐veratroylkaracoline ( 4 ) and 8‐O‐ethylaustroconitine B ( 5 ). 相似文献
17.
Five new β‐carboline‐type alkaloids, dichotomines F–J ( 1 – 5 , resp.), along with nine known compounds, dichotomides I, III, V, and VII ( 6 – 9 , resp.), stellarines A and C ( 10 – 11 , resp.), dichotomine B ( 12 ), glucodichotomine B ( 13 ), and 1‐acetyl‐3‐carboxy‐β‐carboline ( 14 ), were isolated from the roots of Chinese medicinal plant Stellaria dichotoma L. var. lanceolata. Their structures were determined by chemical and spectroscopic means. Compounds 12 and 13 exhibited moderate cytotoxicity. 相似文献
18.
Xing‐Yun Chai Zheng‐Ren Xu Hong‐Yan Ren Hai‐Ming Shi Ya‐Nan Lu Fei‐Fei Li Peng‐Fei Tu 《Helvetica chimica acta》2007,90(11):2176-2185
Eight new benzoylated gentisyl alcohol (=2‐(hydroxymethyl)benzene‐1,4‐diol) glucosides, itosides A–H ( 1 – 8 ), together with the new pyrocatechol (=benzene‐1,2‐diol) glycoside itoside I ( 9 ) were isolated from the bark and twigs of Itoa orientalis (Flacourtiaceae). In itosides B–D ( 2 – 4 ), the gentisyl alcohol moiety was esterified by 1‐hydroxy‐6‐oxocyclohex‐2‐ene‐1‐carboxylic acid, while itosides E–H ( 5 – 8 ) contained instead an additional 2‐hydroxybenzoic acid moiety. The compounds were accompanied by the known derivatives 4‐hydroxytremulacin ( 10 ), poliothyrsoside ( 11 ), poliothyrsin ( 12 ), homaloside D ( 13 ), tremulacin, and pyrocatechol β‐D ‐glucopyranoside. The structures of the new compounds were elucidated by spectral and chemical methods. 相似文献
19.
Jiaying Li Jinwei Ren Li Bao Tao Jin Wenzhao Wang Yunfei Pei Xingzhong Liu Erwei Li 《Helvetica chimica acta》2016,99(1):63-69
Trichodermates A – F ( 1 – 6 , resp.), six new trichothecene polyunsaturated octadioic acid esters, and (?)‐harzianum B ( 7 ) were isolated from the fermentation extract of Trichoderma sp., a plant pathogenic fungus isolated from stem rot of an unidentified tree in Thailand. The structures of 1 – 7 were elucidated by NMR experiments. The absolute configuration at C(12) in 3 was assigned by in situ dimolybdenum circular dichroism method, whereas that in 7 was deduced after hydrolysis of 7 to 8 via modified Mosher's method. Compounds 1 and 2 showed modest cytotoxic activities against the K562 (human myelogenous leukemia) cell line with IC50 values of 12.12 and 13.08 μM , respectively. 相似文献
20.
Xiang‐Dong Qin Yan Zhao Yuan Gao Fu‐Cai Ren Shu Yang Fei Wang 《Helvetica chimica acta》2015,98(9):1325-1331
Three novel curcuminoids, curcumaromins A–C ( 1 – 3 , resp.), along with a known compound, longiferone B ( 4 ) were isolated from Curcuma aromatica Salisb . The structures of the new compounds were elucidated as (1E,4Z,6E)‐5‐hydroxy‐7‐{4‐hydroxy‐3‐[(1R*,6R*)‐3‐methyl‐6‐(propan‐2‐yl)cyclohex‐2‐en‐1‐yl)phenyl}‐1‐(4‐hydroxyphenyl)hepta‐1,4,6‐trien‐3‐one ( 1 ), 2,3‐dihydro‐2‐(4‐hydroxyphenyl)‐6‐[(E)‐2‐(4‐hydroxyphenyl)ethenyl]‐5‐[(1R*,6R*)‐3‐methyl‐6‐(propan‐2‐yl)cyclohex‐2‐en‐1‐yl]‐4H‐pyran‐4‐one ( 2 ), and (1E,6E)‐1,7‐bis(4‐hydroxyphenyl)‐4‐[(1R*,6R*)‐3‐methyl‐6‐(propan‐2‐yl)cyclohex‐2‐en‐1‐yl]hepta‐1,6‐diene‐3,5‐dione ( 3 ) on the basis of spectroscopic analysis. Curcumaromins A–C ( 1 – 3 ) represented the first examples of menthane monoterpene‐coupled curcuminoids. The known compound, longiferone B ( 4 ), was the first daucane sesquiterpene isolated from the genus Curcuma. 相似文献