氯代二苯基锗氨荒酸酯的合成及表征

以二苯基二氯化锗和氨荒酸钠为原料,合成了十三种氯代二苯基锗氨荒酸酯Ph2GeCl(S2CNRR'),利用元素分析、IR、1^HNMR、UV和MS表征了这些化合物的结构,确定了氨荒酸基是非均性的双齿形式与锗原子配位。生物活性测试表明,该类化合物对KB和BeL癌细胞具有较好的抑制活性。     

氯·氨荒酸基·二丁基锡(Ⅳ)配合物的合成和性质

合成了 13种新的氯·氨荒酸基·二丁基锡 ?配合物 (n C4H9)2Sn(C1)S2CNRR′。通过元素分析、 IR、 UV、 1H NMR及 MS对这些配合物进行了表征,结果表明,氨荒酸基是以双齿形式与锡原子配位。初步生物活性测试表明,部分配合物具有较强的抗癌活性。     

铋配合物[Bi(S_2CNC_5H_(10))_2(NO_3)]·[1,10-Phen]·0.5H_2O的合成及晶体结构

由于铋的无毒性、不致癌性以及铋配合物的特殊生物活性,使得铋配合物的研究受到人们的重视。氨荒酸盐及其衍生物是一类有效杀菌剂,已作为植物叶面杀菌剂较广泛地应用,而邻菲咯啉又是一种抑菌剂。把这几类具有生物活性的原料合为一体,应得到具有高生物活性的铋配合物,近期人们的     

双氨荒酸基二丁基锡(Ⅳ)配合物的合成与性质

丁基锡配合物;生物活性;双氨荒酸基二丁基锡(Ⅳ)配合物的合成与性质     

一维链状铋配合物[Bi(S2CNC5H10)2·(NO3)]∞的合成及晶体结构

利用硝酸铋和哌啶氨荒酸盐反应,合成了一维链状铋配合物[Bi(S2CNC5H10)2?(NO3)]∞。通过元素分析和红外光谱对其结构进行了表征。用X-射线单晶衍射测定了该配合物的晶体结构,测试结果表明:配合物晶体属单斜晶系,空间群P21/c,a=13.802(3),b=6.2005(13),c=22.587(5)?,β=103.509(3)o,V=1879.5(7)?3,Mr=591.53,Z=4,F(000)=1136,Dc=2.090g/cm3,μ(MoKα)=9.840mm–1,R=0.0301,wR=0.0399。在该配合物中,铋原子为六配位的畸变八面体构型。通过硝酸根的桥连作用,形成了一维链状结构。     

氨荒酸膦酸树脂的合成及应用.Ⅰ.树脂的合成

本文以丙烯酸甲酯为原料,经过聚合,胺化,磷化,氨荒酸化等反应,合成了氨荒酸膦酸螯合树脂,探讨了影响各步功能基化反应的反应条件。     

二苄基锡双氨荒酸酯的合成

由二苄基二氯化锡与氨荒酸盐反应，合成了１０个新的二苄基锡双氨荒酯化合物，利用元素分析，ＩＲ和＾１ＮＮＭＲ表征了这些化合物的结构。     

氯·杂环羧酸根·二苯基合锗(Ⅳ)的合成及生物活性研究

通过二苯基二氯化锗和杂环羧酸盐以11摩尔比反应,合成了一系列氯@杂环羧酸根@二苯基合锗(Ⅳ),用元素分析、红外光谱、核磁共振氢谱和质谱表征了这些配合物的结构,红外光谱数据表明,配体杂环羧酸根是以单齿形式与锗原子配位.生物活性测试表明,这些配合物显示较强的体外抗癌活性.     

三苯基锗氨荒酸酯的合成

合成了10个新的三苯基锗氨荒酸酯类化合物,利用元素分析,IR、^1HNMRMS表征了它们的结构。部分化合物初步生物活性测试结果表明,该类化合物对KB,HCT和Bel癌细胞具有较好的抑制活性。     

氨荒酸膦酸树脂的合成及应用.Ⅱ.树脂的应用

本文以原子吸收光谱为检测手段,将氨荒酸膦酸树脂应用于地下水中Zn,Cd,Co,Cr,Cu,Mn,Ni,Pb等八种痕量元素的同时分析,取得了满意的结果。用美国环保局标准水样评价此分析方法的可靠性,结果表明分析结果的方差小,回收率高。文中还探讨了氨荒酸膦酸树脂对Hg~(2+)的吸附性能和吸附机理,表明树脂吸附Hg~(2+)的过程是受内扩散控制的。     

Dichroism of absorption and polarization of phosphorescence of molecules of the closed form of nitrobenzospirothiopyran

The spectral-polarization characteristics of absorption and phosphorescence of molecules of the initial form of nitro-substituted indolinospirobenzothiopyran were studied in oriented polyethylene films and in solutions with different polarity. An oscillator model of the electron transitions responsible for the formation of absorption and luminescence spectra was suggested. It was established that the principal differences in the spectral and photophysical properties of the compound studied and its oxygen-containing analog are associated with the fact that the electronegativity of the S atom is lower than that of the O atom. Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 6, pp. 1143–1146, June, 1997.     

非那雄胺合成工艺改进

非那雄胺能抑制5α-还原酶的活性,明显降低二氢睾酮水平,是一种治疗良性前列腺增生的有效药品。该合成工艺以甾烯酮酸为原料,将其与氯化亚砜反应,无须分离即与叔丁胺反应得17β-酰胺化合物,再氧化开环,环合,氢化,脱氢合成了非那雄胺。经元素分析、IR、1HNMR、13CNMR、MS分析表征了其结构。该法无须使用昂贵的2,2-二吡啶二硫化物和剧毒药品苯亚硒酸酐,且以乙酸铵代替氨气,降低了对设备的要求和腐蚀,更适用于工业生产。     

Determination of heats of detonation and influence of components of composite explosives on heats of detonation of high explosives

The heats of detonation of 20 simple high explosives and explosive mixtures were determined by means of an adiabatic detonation calorimeter designed by the authors. The results indicated that the performance of the instrument was reliable and the experimental data were very accurate. For explosive mixtures, there was a linear accumulative relationship between the heats of detonation of the explosive mixture and its components. Accordingly, the heats of detonation of explosive mixtures could be calculated directly from the heats of detonation of simple explosives and the characteristic heats of other components. The experiments showed that the gold or brass shell of the cylindrical charge could be substituted by a thick-walled porcelain shell, which had the advantage of cheapness.

     

Synthesis of phenolic components of Grains of Paradise

Two vanilloids, (5E)-8-(4-hydroxy-3-methoxyphenyl)oct-5-en-4-one (1) and 4-[3-hydroxydecyl]-2-methoxyphenol (2), isolated from the dried seeds of Grains of Paradise (Aframomum melegueta), were synthesized; the latter compound was made as the S-enantiomer and the material derived from the seeds was found to be a 1:1.7 mixture of the R and S isomers. The synthetic route used should allow the preparation of analogs having extended alkyl chains and consequently different lipophilicity, and 3, a homolog of 2, was also prepared.     

Summary of development of the theory of stability of colloids and thin films

In this review, the research of the author in the field of colloidal systems is summarized. The factors influencing colloidal stability are systematized and analyzed. Examples are presented to illustrate the practical utilization of the theory of stability of colloids and thin films.This review was prepared on the basis of the works of the author, which were awarded the State Premium for 1991 in the field of science and technology, chemistry section.Institute of Physical Chemistry, Russian Academy of Sciences, 117915 Moscow. Translated from Izvestiya Akademii Nauk, Seriya Khimicheskaya, No. 8, pp. 1708–1717, August, 1992.     

Study of hydration of two cements of different strengths

Main hydration products of two cement pastes, i.e. CSH-gel, portlandite (P) (and specific surface S) were studied by static heating, and by SEM, TEM and XRD, as a function of cement strength (C-33 and C-43) hydration time (th) and subsequent hydration in water vapour.Total change in mass on hydration and air drying, M_o, increased with strength of cement paste and with hydration time. Content of water escaping at 110 to 220°C, defined as water bound with low energy, mainly interlayer and hydrate water, was independent on cement strength but its content increased with (th). Content of chemically bound (zeolitic) water in CSH-gel, escaping at 220-400°C, was slightly dependent on strength and increased with (th). It was possibly derived from the dehydroxylation of CSH-gel and AFm phase. Portlandite water, escaping at 400-500°C, was independent on cement strength and was higher on longer hydration. Large P crystals were formed in the weaker cement paste C-33. Smaller crystals were formed in C-43 but they increased with (th). Carbonate formated on contact with air (calcite, vaterite and aragonite), decomposed in cement at 600-700^oC. It was high in pastes C-33(1 month) and C-43(1 month), i.e. 5.7 and 3.3%, respectively; it was less than 1% after 6 hydration months (low sensitivity to carbonation) in agreement with the XRD study showing carbonates in the air dry paste (1month), and its absence on prolonged hydration (6 months) and on acetone treatment. Water vapour treatment of (6 months) pastes or wetting-drying increased this sensitivity.Nanosized P-crystals, detected by TEM, could contribute to the cement strength; carbonate was observed on the rims of gel clusters.This revised version was published online in November 2005 with corrections to the Cover Date.     

氯氧化镁生成热的研究

用氧化镁氯化镁水溶液制备了8水合氯氧化镁[nMg(OH)2·MgCl2·8H2O], 并测定了其在盐酸中的溶解热, 实验结果表明, 氯氧化镁溶解热与n值呈线性关系, 根据溶解热求出5Mg(OH)2·MgCl2·8H2O和3Mg(OH)2·MgCl2·8H2O的生成热分别为-7727.1和5888.1kJ·mol^1^-。     

Thermodynamics of the formation of oxosulfides of rare-earth elements

The enthalpies of solution of several oxosulfides of rare-earth elements and the high-temperature enthalpies of oxosulfides and oxosulfates of lanthanum and yttrium were measured using solution calorimetry and high-temperature microcalorimetry techniques. Standard enthalpies of formation and some thermodynamic properties of oxosulfides and oxosulfates were calculated. Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 2 pp. 294–297, February, 1997.     

恶臭嗅辨实验室建设探讨

针对恶臭测试的环境影响问题,提出了解决的实例方案,并对方案的要点及优缺点进行讨论,此方案在实际操作中具有较好的效果。