共查询到19条相似文献,搜索用时 93 毫秒
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通过2,4-二苯基-2,3-二氢-1H-1,5-苯并二氮杂与苯甲酰氯苯腙的[2+3]环加成反应制备了标题化合物,用X射线单晶衍射仪测定了其晶体结构。晶体属正交晶系,空间群为Fdd2.晶胞参数:a=1.7628(4)nm,b=5.7512(12)nm,c=1.0227nm,V=10.368(5)nm3,Z=16,Dc=1.262g·cm-3,μ=0.075mm-1,F(000)=4160,1139个可观测衍射点,R=0.0461,Rw=0.0560. 相似文献
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α-四氢萘酮的乙氧羰基腙(1)经LTA氧化, 得到α-偶氮-α-乙酰氧基化合物2. 在AlCl3作用下, 化合物2脱去乙酰氧基产生重氮正离子中间体3, 再经与腈的1,3-偶极环加成、 [1,2]-迁移扩环、碱性水解和与苦味酸作用, 得到新型[1,2,4]-三唑并[1,5-a][1]苯并氮杂(艹卓)苦味酸盐6a~6c. 以2,3-二氢-1-茚酮为底物, 采用相同的合成路线, 合成了1,2,4-三唑并[1,5-a]-二氢喹啉苦味酸盐12a~12c. 相似文献
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将取代色满酮(1)与芳肼反应生成的腙与HNCO发生[3+2]环加成反应,加成产物(2)经氧化得到偕偶氮异氰酸酯(3).化合物3在HBF4的催化下发生环化-重排反应,得到新颖的三环系2-氧代-1,2,4-三唑并[3,2-d][1,5]苯并氧氮杂(艹卓 )化合物5a~5g. 相似文献
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1,2,4-三唑并[3,2-d][1,5]-苯并氧氮杂(艹/卓)化合物的合成 总被引:1,自引:1,他引:0
苯并二氢吡喃-4-酮的芳腙(1)衍生的偶氮基碳正离子(3)与腈发生1,3-偶极环加成反应,加成产物(4)通过「1,2」-迁移扩环重反应,形成新颖的三环系杂环化合物1,2,4-三唑并「3,2-d」「1,5」-苯并氧氮杂Zhuo化合物5a-5k。 相似文献
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1,3,3a,5—四苯基—3a,4,5,11—四氢—3H,6H—1,2,4—三唑并( … 总被引:3,自引:3,他引:3
通过2,4-二苯基-2,3-二氢-1H-1,5-苯并二氮杂Zuo与苯甲酰氯苯腙的(2+3)环加成反应制备了标题化合物,用X射线单晶衍射仪测定了其晶体结构,晶体属正交晶系,空间群为Fdd2.晶胞参数;a=1.7628(4)nm,b=5.7512(12)nm,c=1.0227nm,V=10.368(5)nm^3,Z=16,Dc=1.262g.cm^-3,μ=0.075mm^-1,F(000)=4160 相似文献
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通过2-甲基-4-对甲苯基-1-苯甲酰基-2,3-二氢-1H-1,5-苯并二氮杂与由不对称1-苯基-2-偶氮-1,3-丁二酮热解产生的a-羰基烯酮的[2+4]环加成反应制备了标题化合物(C34H30N2O3,Mr=514.62),用X射线衍射测定了其单晶结构。晶体属单斜晶系,空间群为P21/n,a=11.560(1),b=19.058(3),c=13.207(2)A,β=106.82(1)°,V=2785.2(7)A3,Z=4,Dc=1.230g.cm-3,MoKa(λ=0.71073A),μ=0.064mm-1,F(000)=1088,2278个可观测衍子射点,R=0.046,Rw=0.049。分子骨架为由苯环、具有类扭船式构象的七元二氮杂环和略微扭曲的唑酮环构成的三环体系。 相似文献
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将取代色满酮(1)与芳肼反应生成的腙与HNCO发生[3+2]环加成反应,加成产物(2)经氧化得到偕偶氮异氰酸酯(3).化合物3在HBF4的催化下发生环化-重排反应,得到新颖的三环系2-氧代-1,2,4-三唑并[3,2-d][1,5]苯并氧氮杂化合物5a~5g. 相似文献
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Lin-Xia Xiao Ke Li De-Qing Shi 《Phosphorus, sulfur, and silicon and the related elements》2013,188(12):3156-3165
An important building block, diethyl [(5-amino-4-cyano-3-methylsulfanyl-pyrazol-1-yl)–(4-fluorophenyl)methyl] phosphonate (3) was efficiently synthesized via the condensation of 1-hydrazino-1-(4-fluorophenyl)methyl phosphonate (1) with 2-[bis(methylthio)methylene]malononitrile (2).3 reacted with triethyl orthoformate to afford diethyl [(4-cyano-5-ethoxymethyleneamino-3-methylsulfanyl-pyrazol-1-yl)-(4-fluorophenyl)methyl] phosphonate (4), which reacted with various acyl hydrazines in refluxing 2-methoxyethanol to provide the target compounds (5) in good yields directly. The results of preliminary bioassay indicated that compounds 5 possess potent herbicidal activity against the roots of monocotyledonous (barnyard grass) and dicotyledonous (oil rape) plants, and could be further developed as potential herbicides. 相似文献
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The fragmentation pathways of nineteen 1,3a,5-trisubstituted 3a,4,5,11-tetrahydro- 1,2,4-oxadiazolo[5,4-d][1,5]benzothiazepines have been studied with the aid of mass-analyzed ion kinetic energy spectrometry and exact mass measurements using fast-atom bombardment ionization. All compounds show a tendency to eliminate a neutral propene, or substituted or unsubstituted styrene, from the thiazepine ring to yield 1,2,4-oxadiazolo[5,4-b][1,3]benzothiazole ions, and further undergo reverse 1,3-dipolar cycloadditions to give benzothiazole ions. The formation of stable conjugated fused tetracyclic systems, substituted 1,2,4-oxadiazolo[5,4-f]phenanthridine ions, was also observed. Copyright © 1999 John Wiley & Sons, Ltd. 相似文献
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M. Rahimizadeh A. Davoodnia M. M. Heravi M. Bakavoli 《Phosphorus, sulfur, and silicon and the related elements》2013,188(12):2923-2929
A simple and fast synthesis of 6-aryl-3-substituted-5H-[1,2,4]-triazolo[4,3-b][1,2,4]triazoles 4 in high yields has been developed by microwave assisted heterocyclization of N-(3-methylthio-5-substituted-4H-1,2,4-triazol-4-yl)benzenecarboximidamides 3 . The effectiveness of the microwave irradiation and conventional heating for the formation of compounds 4 has been investigated. 相似文献
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F. Melani L. Cecchi V. Colotta D. Catarzi G. Filacchioni 《Journal of heterocyclic chemistry》1992,29(4):819-823
The synthesis of the new tricyclic heteroaromatic system 5H-1,2,4-triazolo[5,1-c][1,4]benzodiazepine, diazaanalogue of 5H-pyrrolo[2,1-c][1,4]benzodiazepine, which is the common feature of some antitumor antibiotics, is reported. The structure of the new tricyclic system and of some of its key intermediates is assigned by means of nuclear magnetic resonance studies. 相似文献
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L. Kosychova Z. Stumbreviciute L. Pleckaitiene R. Janciene B. D. Puodziunaite 《Chemistry of Heterocyclic Compounds》2004,40(6):811-815
A one-pot synthetic approach to the novel 5,6-dihydro-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepines by thermal cyclization of 4-acylhydrazino-2,3-dihydro-1H-1,5-benzodiazepines is described. 相似文献