一类具有阶段结构的捕食-被捕食模型的全局稳定性（英文）

A Holling type III predator-prey model with stage structure for prey is investigated. By analyzing the corresponding characteristic equations, the local stability of each of feasible equilibria of the system is discussed. By using the uniformly persistence theory, the system is proven to be permanent if the coexistence equilibrium exists. By using Lyapunov functionals and La Salle's invariance principle, it is shown that the two boundary equilibria is globally asymptotically stable when the coexistence equilibrium is not feasible. By using compound matrix theory, the sufficient conditions are obtained for the global stability of the coexistence equilibrium. At last, numerical simulations are carried out to illustrate the main results.     

疾病在食饵中流行的捕食与被捕食模型的分析

分析并建立了疾病在食饵中传播的生态-传染病模型,同时考虑到两种群都受密度制约因素的影响,讨论了模型解的有界性和各平衡点的存在性,利用Routh-Hurwitz判据证明了各平衡点的局部渐进稳定性,通过构造Lyapunov函数分析了各平衡点的全局渐进稳定性,得到了疾病存在与否的充分性条件.     

Dynamics of an intra-host model of malaria with a constant drug efficiency

In this paper, we investigate the dynamics of an intra-host model of malaria with logistic red blood growth, treatment and immune response. We provide a theoretical study of the model. We derive the basic reproduction number $\mathcal R_f$ which determines the extinction and the persistence of malaria within the body of a host. We compute equilibria and study their stability. More precisely, we show that there exists a threshold parameter $\zeta$ such that if $\mathcal R_f\leq\zeta\leq1$, the disease-free equilibrium is globally asymptotically stable. However, if $\mathcal R_f>1$, there exist two malaria infection equilibria which are locally asymptotically stable: one malaria infection equilibrium without immune response and one malaria infection equilibrium with immune response. The sensitivity analysis of the model has been performed in order to determine the impact of related parameters on outbreak severity. The theory is supported by numerical simulations. We also derive a spatio-temporal model, using Diffusion-Reaction equations to model parasites dispersal. Finally, we provide numerical simulations for parasites spreading, and test different treatment scenarios.     

Dynamics of a generalized Ricker–Beverton–Holt competition model subject to Allee effects

In this article, we propose and study a generalized Ricker–Beverton–Holt competition model subject to Allee effects to obtain insights on how the interplay of Allee effects and contest competition affects the persistence and the extinction of two competing species. By using the theory of monotone dynamics and the properties of critical curves for non-invertible maps, our analysis show that our model has relatively simple dynamics, i.e. almost every trajectory converges to a locally asymptotically stable equilibrium if the intensity of intra-specific competition intensity exceeds that of inter-specific competition. This equilibrium dynamics is also possible when the intensity of intra-specific competition intensity is less than that of inter-specific competition but under conditions that the maximum intrinsic growth rate of one species is not too large. The coexistence of two competing species occurs only if the system has four interior equilibria. We provide an approximation to the basins of the boundary attractors (i.e. the extinction of one or both species) where our results suggests that contest species are more prone to extinction than scramble ones are at low densities. In addition, in comparison to the dynamics of two species scramble competition models subject to Allee effects, our study suggests that (i) Both contest and scramble competition models can have only three boundary attractors without the coexistence equilibria, or four attractors among which only one is the persistent attractor, whereas scramble competition models may have the extinction of both species as its only attractor under certain conditions, i.e. the essential extinction of two species due to strong Allee effects; (ii) Scramble competition models like Ricker type models can have much more complicated dynamical structure of interior attractors than contest ones like Beverton–Holt type models have; and (iii) Scramble competition models like Ricker type competition models may be more likely to promote the coexistence of two species at low and high densities under certain conditions: At low densities, weak Allee effects decrease the fitness of resident species so that the other species is able to invade at its low densities; While at high densities, scramble competition can bring the current high population density to a lower population density but is above the Allee threshold in the next season, which may rescue a species that has essential extinction caused by strong Allee effects. Our results may have potential to be useful for conservation biology: For example, if one endangered species is facing essential extinction due to strong Allee effects, then we may rescue this species by bringing another competing species subject to scramble competition and Allee effects under certain conditions.     

Interactional models for adults of two populations with maturation delays

This paper is concerned with interactional models for adults of two species delayed by their mature periods. The existence and local stability of equilibria are discussed thoroughly for competitive systems, cooperative systems and predator-prey systems, respectively. For systems with interaction of competition and cooperation, it is found that the two populations are uniformly persistent if the positive equilibrium is stable. For predator-prey interaction, however, some further conditions are needed to guarantee the persistence of the systems.     

Dynamical analysis of a sex-structured Chlamydia trachomatis transmission model with time delay

The effect of using time delay to model the latency period of Chlamydia trachomatis infection is explored, by designing a deterministic two-sex model for Chlamydia transmission dynamics in a population. The resulting delay differential equation model is shown to undergo the phenomenon of backward bifurcation, where a stable disease-free equilibrium co-exists with one or more stable endemic equilibria when the associated reproduction threshold is less than unity. This phenomenon arises due to the re-infection of individuals who recovered from the disease. Using permanence theory, it is shown that Chlamydia will persist in the population whenever the associated reproduction threshold exceeds unity. It is further shown that long latency period could induce positive (decrease disease burden) or negative (increase disease burden) population-level impact depending on the sign of a certain epidemiological threshold quantity and some other conditions. Furthermore, this study shows that adding a time delay (to model the latency period) does not alter the main equilibrium dynamics (with respect to the effective control or persistence of the disease in the community) of the corresponding non-delayed Chlamydia transmission model considered in our earlier study Sharomi and Gumel (2009) [7].     

具有Monod-Haldane功能反应的一类食物链模型的动力学行为

该文研究了一个由食饵种群、捕食者种群和杂食者种群所构成的食物链系统, 其捕食功能反应为Monod-Haldane功能反应. 应用定性分析和Hopf分支理论, 得到了该系统边界平衡点的全局稳定性和周期解存在性的判别准则. 为了概括和归类这个系统的全局动力学行为,该文得到了具有不同动力学行为的参数区域. 应用MATLAB软件,该文提供了一个例子来展示这些结论, 并且表明: 这个系统能够产生非常复杂的动力学行为.     

A competition un-stirred chemostat model with virus in an aquatic system

A reaction–diffusion system of two bacteria species competing a single limiting nutrient with the consideration of virus infection is derived and analysed. Firstly, the well-posedness of the system, the existence of the trivial and semi-trivial steady states, and some prior estimations of the steady states are given. Secondly, a single species subsystem with virus is studied. The stability of the trivial and semi-trivial steady states and the uniform persistence of the subsystem are obtained. Further, taking the infective ability of virus as a bifurcation parameter, the global structure of the positive steady states and the effect of virus on the positive steady states are established via bifurcation theory and limiting arguments. It shows that the backward bifurcation may occur. Some sufficient conditions for the existence, uniqueness and stability of the positive steady state are also obtained. Finally, some sufficient conditions on the existence of the positive steady states for the full system are derived by using the fixed point index theory. Some results on persistence or extinction for the full system are also obtained.     

A two species competition model under the simultaneous effect of toxicant and disease

A mathematical model is proposed to study the simultaneous effects of toxicants and infectious diseases on a competing species system. It is assumed that the competing populations are adversely affected by the toxicant and one of them is vulnerable to an infectious disease. In this paper, two models are studied separately. The first model is developed to study the effect of only infectious diseases on the existence of a two competing species system in the absence of a toxicant, whereas in the second model the presence of a toxicant is also taken into account. In both the models, conditions for the existence of interior equilibria are derived. The models are analyzed using stability theory, and conditions for the nonlinear stability of the interior equilibria are obtained using Lyapunov’s direct method. Further, the models are studied numerically by taking two sets of numerical values for each model and the results are compared.     

Global Qualitative Analysis for a Ratio-Dependent Predator-Prey Model with Delay

A ratio-dependent predator-prey model with time lag for predator is proposed and analyzed. Mathematical analyses of the model equations with regard to boundedness of solutions, nature of equilibria, permanence, and stability are analyzed. We note that for a ratio-dependent system local asymptotic stability of the positive steady state does not even guarantee the so-called persistence of the system and, therefore, does not imply global asymptotic stability. It is found that an orbitally asymptotically stable periodic orbit exists in that model. Some sufficient conditions which guarantee the global stability of positive equilibrium are given.     

A compartmental model for global spread dynamics of malware under mutation

Malware mutation is pervasive among networks. Modeling and understanding its propagation characteristics have been of great importance. In this study, a new compartmental model that extends the present model by incorporating mutated malware into the modeling process as a separate dynamic variable is proposed and theoretically analyzed to deepen the understanding of the spreading mechanisms of mutated malware. The model involves two equilibria, namely, malware‐free equilibrium and malware equilibrium, wherein both have proven to be locally and globally asymptotically stable through the Routh‐Hurwitz criterion and Lyapunov functional approach, respectively. An epidemic threshold is obtained that clearly forms the boundary among the comprehensive dynamics of the model between two distinct ramifications: one with mutation infection prevalence and the other without any mutation infection. Both are incarnated via the existence and stability of the equilibria admitted by the model. Further analyses show that the mutation is related not only to the epidemic threshold, but also to the malware prevalence level. The numerical simulations based on the analytic results demonstrate that the diffusion of mutated malware can fall away or can be maintained at a suitable level.     

HIV low viral load persistence under treatment: Insights from a model of cell-to-cell viral transmission

HIV infection persists despite long-term administration of antiretroviral therapy. The mechanisms underlying HIV persistence are not fully understood. Direct viral transmission from infected to uninfected cells (cell-to-cell transmission) may be one of them. During cell-to-cell transmission, multiple virions are delivered to an uninfected cell, making it possible that at least one virion can escape HIV drugs and establish infection. In this paper, we develop a mathematical model that includes cell-to-cell viral transmission to study HIV persistence. During cell-to-cell transmission, it is assumed that various number of virus particles are transmitted with different probabilities and antiretroviral therapy has different effectiveness in blocking their infection. We analyze the model by deriving the basic reproduction number and investigating the stability of equilibria. Sensitivity analysis and numerical simulation show that the viral load is still sensitive to the change of the treatment effectiveness in blocking cell-free virus infection. To reduce this sensitivity, we modify the model by including density-dependent infected cell death or HIV latent infection. The model results suggest that although cell-to-cell transmission may have reduced susceptibility to HIV drugs, HIV latency represents a major reason for HIV persistence in patients on suppressive treatment.     

Qualitative analysis on a diffusive SIS epidemic system with logistic source and spontaneous infection in a heterogeneous environment

In this paper, we consider an SIS epidemic reaction–diffusion model with spontaneous infection and logistic source in a heterogeneous environment. The uniform bounds of solutions are established, and the global asymptotic stability of the constant endemic equilibrium is discussed in the case of homogeneous environment. This paper aims to analyze the asymptotic profile of endemic equilibria (when it exists) as the diffusion rate of the susceptible or infected population is small or large. Our results on this new model reveal that varying total population and spontaneous infection can enhance persistence of infectious disease, which may provide some implications on disease control and prediction.     

一类HIV病毒动力学模型的全局稳定性与周期解

建立了一类较广泛的HIV感染CD4+T细胞病毒动力学模型,给出了一个感染细胞在其整个感染期内产生的病毒的平均数(基本再生数)R0的表达式,运用Lyapunov原理和Routh-Hurwitz判据得到了该模型的未感染平衡点与感染平衡点的存在性与稳定性条件.同时也得到了模型存在轨道渐近稳定周期解和系统持续生存的条件,并通过数值模拟验证了所得到的结果.     

一类具有时滞的HIV-1感染模型全局性质

重新考虑了一类带有时滞的HIV-1感染模型.运用Hale和Waltmann持续生存理论,得到了再生数R＞1,系统中种群是持续生存的;通过构造Lyapunov泛函,证明了系统中平衡态的全局稳定性.得到了再生数R＞1能够完全确定模型全局动力学性质.     

Existence and asymptotic behavior of solutions for a mathematical ecology model with herd behavior

In this work, we consider a prey-predator model with herd behavior under Neumann boundary conditions. For the system without diffusion, we establish a sufficient condition to guarantee the local asymptotic stability of all nontrivial equilibria and prove the existence of limit cycle of our proposed model. For the system with diffusion, we consider the long time behavior of the model including global attractor and local stability, and the Hopf and steady-state bifurcation analysis from the unique homogeneous positive steady state are carried out in detail. Furthermore, some numerical simulations to illustrate the theoretical analysis are performed to expand our theoretical results.     

Influence of predator mutual interference and prey refuge on Lotka–Volterra predator–prey dynamics

A Lotka–Volterra predator–prey model incorporating a constant number of prey using refuges and mutual interference for predator species is presented. By applying the divergency criterion and theories on exceptional directions and normal sectors, we show that the interior equilibrium is always globally asymptotically stable and two boundary equilibria are both saddle points. Our results indicate that prey refuge has no influence on the coexistence of predator and prey species of the considered model under the effects of mutual interference for predator species, which differently from the conclusion without predator mutual interference, thus improving some known ones. Numerical simulations are performed to illustrate the validity of our results.     

Dynamical analysis of a Lotka-Volterra learning-process model

A Lotka-Volterra learning-process model was proposed by Monteiro and Notargiacomo in [{\it Commum. Nonlinear Sci. Numer. Simulat.} {\bf 47}(2017), 416-420] to approach learning process as an interplay between understanding and doubt. They studied the stability of the boundary equilibria and gave some numerical simulations but no further discussion for bifurcations. In this paper, we study the qualitative properties of the interior equilibria and a singular line segment completely. Moreover, we discuss their bifurcations such as transcritical, pitchfork, Hopf bifurcation on isolated equilibria and transcritical bifurcation without parameters on non-isolated equilibria. Finally, we also demonstrate these analytical theory by numerical simulations.     

The effect of diffusion for the multispecies Lotka–Volterra competition model

The purpose of this paper is to study the effect of diffusion in the existence of non-constant steady states for the Lotka–Volterra competition-diffusion system with three species, under Neumann boundary conditions. It will be shown that two large diffusion rates prevent the appearance of non-constant steady states, while if just one species diffuses fast non-constant equilibria may arise. The existence is shown by two methods, degree theory and bifurcation techniques. The stability of bifurcating steady states will be established.     

具有急慢性阶段的SIS流行病模型的稳定性

本文系统研究了具有急性和慢性两个阶段的SIS流行病模型.由两节构成,第一节建立和研究了具有急性和慢性两个阶段的SIS流行病模型,该模型是由三个常微分方程构成的方程组;第二节在第一节的基础上建立和研究了具有慢性病病程的SIS流行病模型;该模型既含有常微分方程,又含有偏微分方程.假设所研究的国家或地区的总人口N(t)服从增长规律: N'(t)=A—μN(t),运用微分方程和积分方程中的理论和方法,得到了这两个模型再生数R0的表达式．证明了无病平衡态的全局渐近稳定性,给出了两模型地方病平衡态的存在性和稳定性条件．