共查询到20条相似文献,搜索用时 15 毫秒
1.
I. N. Bardasov A. Yu. Alekseeva N. L. Malyshkina O. V. Ershov D. A. Grishanov 《Russian Journal of Organic Chemistry》2016,52(6):830-833
Three-component condensation of aliphatic aldehydes with resorcinol and malononitrile dimer (2-aminoprop-1-ene-1,1,3-tricarbonitrile) afforded the corresponding 5-alkyl-2,4-diamino-8-hydroxy-5H-chromeno[2,3-b]pyridine-3-dicarbonitriles. 相似文献
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E. G. Paronikian Sh. F. Akopian A. S. Noravian 《Chemistry of Heterocyclic Compounds》2008,44(8):1003-1008
A new methods have been developed for the synthesis of condensed pyrido[2,3-b]thieno[3,2-d]pyrimidines based on cyclic derivatives
of 4-cyanopyridine-3-thiones. The presence of two different reactive functional groups NH2 and CONH gives the possibility of carrying out different conversions of thieno[2,3-b]pyridines.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, 1245–1252, August, 2008. 相似文献
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Salman Taheri Ali Asghar Mohammadi Reza Ahdenov Robab Azarlak 《Journal of the Iranian Chemical Society》2016,13(7):1301-1306
An efficient one-pot synthesis of fused dihydrothiopyrano[2,3-b]indole-3-carbonitriles has been developed through ultrasound mediated reaction by simply combining malononitrile and various aldehydes with two indoline-2(3H)-thiones. The method has the advantages of high yields, short reaction time, good functional group tolerance and green reaction conditions. 相似文献
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An environmentally benign novel one-pot synthesis of pyridines and pyrido[2,3-d]pyrimidines from chalcones and malononitrile was described. In the reaction under neat conditions using microwave irradiation,
enhancement in the reaction rate and high yields were observed.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 6, pp. 1479–1482, June, 2005. 相似文献
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Tetrabutylammonim fluoride has been used as an efficient catalyst for synthesis of pyrazolo[1,2-b]-phthalazine-5,10-diones and dihydrospiro[indoline-3,1'-pyrazolo[1,2-b]phthalazines] by one-pot three-component reaction of phthalhydrazide, aromatic aldehydes or isatin derivatives, with malononitrile in water under ultrasond irradiation. This rapid method gave the products in high yield. 相似文献
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I. N. Bardasov A. U. Alekseeva D. A. Bezgin O. E. Nasakin O. V. Ershov 《Russian Journal of Organic Chemistry》2018,54(8):1179-1183
An environmentally friendly method has been developed for the preparation of 5H-chromeno[2,3-b]pyridine derivatives in an aqueous medium under ultrasound irradiation. 相似文献
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V. I. Terenin M. A. Butkevich A. S. Ivanov N. A. Tselischeva E. V. Kabanova 《Chemistry of Heterocyclic Compounds》2008,44(1):73-77
The formylation of pyrrolo[1,2-a]pyrazines containing alkyl, aryl, or hetaryl substituents in positions 1 and 6 of the heterocycle
has been studied. It has been shown that formylation of 1-phenyl-and 1-(2 thienyl)pyrrolo[1,2-a]pyrazine occurs selectively
at the α-position of the pyrrole ring. In all of the remaining examples the reaction course depends on substituent, reagent
ratio, and reaction time.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 88–93, January, 2008. 相似文献
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A new efficient method has been developed for the synthesis of highly biologically active pyrano-[4,3-d]pyrazolo[3,4-b]pyridines on the basis of Smiles rearrangement of ethyl [(8-alkyl(aryl)-5-cyano-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridin-6-yl)oxy]acetates. Intermediate acetohydrazides have also been isolated. The proposed procedure is advantageous due to the possibility of avoiding experimentally difficult chlorination stage. 相似文献
11.
Victor V. Dotsenko Sergey G. Krivokolysko Victor P. Litvinov 《Monatshefte für Chemie / Chemical Monthly》2008,139(6):657-661
Morpholinium 3-cyano-4-methyl-6-oxo-1,6-dihydropyridine-2-thiolate upon treatment with primary amines and a formaldehyde excess
under mild conditions produces bis(pyrido[2,1-b][1,3,5]thiadiazin-7-yl)methane derivatives in good yields (67–87%).
Correspondence: Victor V. Dotsenko, State Enterprise “Luganskstandartmetrology”, 91021 Lugansk, Ukraine. 相似文献
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V. A. Osyanin V. Y. Nakushnov Y. N. Klimochkin 《Chemistry of Heterocyclic Compounds》2011,47(6):755-757
The previously unknown heterocyclic system naphtho[1,2-e]pyrazolo[5,1-b][1,3]oxazine was synthesized by the condensation of 1-dimethylaminomethyl-2-naphthols with bromopyrazoles. It is proposed
that the highly reactive o-methylenequinone of the naphthalene series is formed as an intermediate. 相似文献
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R. M. Shlenev S. I. Filimonov A. V. Tarasov A. S. Danilova P. A. Agat’ev 《Russian Journal of Organic Chemistry》2016,52(2):240-243
Methods were developed of indirect introduction of sulfonamide group in the structures of pyrido-[2,1-b]quinazolin-11-one and pyrido[1,2-a]quinazolin-6-one underlain by cyclocondensation of 2-halo-5-(Rsulfamoyl) benzoyl chlorides with derivatives of 2-aminopyridine. The fact of thermal rearrangement of 8-(morpholin-4-ylsulfonyl)pyrido[1,2-a]quinazolin-6-one into isomeric 2-(morpholine-4-ylsulfonyl)pyrido[2,1-b]-quinazolin-11-one was experimentally registered. 相似文献
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E. G. Paronikyan A. S. Noravyan A. S. Harutunyan 《Chemistry of Heterocyclic Compounds》2010,46(8):987-990
Methods have been developed for the synthesis of novel derivatives of pyrano[3,4-c]pyridines, 2,7-naphthyridines, and condensed
pyrido[2,3-d]pyrimidines by condensation of thiopyranthiones. 相似文献
15.
Abolfazl Olyaei Mohammad Sadegh Shahsavari Mahdieh Sadeghpour 《Research on Chemical Intermediates》2018,44(2):943-956
An efficient tandem reaction approach is described to prepare novel benzo[f]chromenes from 2,3-dihydroxynaphthalene, malononitrile and aldehydes using 10 mol% guanidine hydrochloride as the catalyst under solvent-free conditions. The method was also extended to the preparation of novel 12H-benzo[5,6]chromeno[2,3-b]pyridines from 2-aminoprop-1-ene-1,1,3-tricarbonitrile instead of malononitrile under the same reaction conditions. The described one-pot three-component reaction is characterized by short reaction times, high-product yield, mild reaction conditions, simple workup procedure, and simple purification. 相似文献
16.
A. A. Harutyunyan 《Russian Journal of Organic Chemistry》2016,52(7):1012-1017
The reactions of benzene-1,2-diamine with 5-substituted 2-(alkylsulfanyl)-4-methylpyrimidin-6(1H)-ones and 2-(propylsulfanyl)- and 5-iodo-2-(propylsulfanyl)-3,4-dihydroquinazolines at 175–185°C under solvent-free conditions unexpectedly afforded benzo[4,5]imidazo[1,2-a]pyrimidine, benzo[4,5]imidazo[2,1-b]-quinazoline, and 2,2′-(benzene-1,2-diyldiimino)bis[pyrimidin-4(3H)-ones]. The described reaction is the first example of synthesis of these heterocyclic systems by fusion of benzimidazole to pyrimidine or quinazoline and is likely to follow ANRORC mechanism. 相似文献
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A. M. Boguslavskii M. G. Ponizovskii M. I. Kodess V. N. Charushin 《Russian Journal of Organic Chemistry》2005,41(9):1377-1380
Ring-chain transformation of 3-hydroxyiminomethyl-1-methylquinoxalinium iodide into 9-methyl-9,9a-dihydroisoxazolo[4,5-b]quinoxaline was studied. The isoxazole ring in the latter was cleaved by the action of alcohols. 相似文献
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A. E. Shchekotikhin E. K. Shevtsova V. F. Traven’ 《Russian Journal of Organic Chemistry》2007,43(11):1686-1695
4,11-Dialkoxyanthra[2,3-b]furan-5,10-diones containing various substituents in the 3-position were synthesized. Reactions of these compounds with primary and secondary amines resulted in nucleophilic replacement of one or two alkoxy groups by the corresponding amine residues. 4,11-Dialkoxy derivatives of anthra[2,3-b]furan-5,10-dione showed fluorescence with large Stokes shifts (170–200 nm). 相似文献
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V. V. Dabaeva M. R. Bagdasaryan A. S. Noravyan 《Chemistry of Heterocyclic Compounds》2011,47(5):639-643
The reactions of 2-methyl (propyl) substituted 8,8-dimethyl-7,10-dihydro-4H,8H-pyrano[3",4":5',6']pyrido[3',2':4,5]thieno[3,2-d][1,3]oxazines
with primary amines give 2-methyl (propyl) substituted 8,8-di- methyl-7,10-dihydro-8H-pyrano[3",4":5',6']pyrido[3',2':4,5]thieno[3,2-d][1,3]pyrimidin-4(3H)-ones
or 3-acetyl-N-alkyl- and N-alkyl-3-butyrylamino-7,7-dimethyl-7,8-dihydro-5H-pyrano[4,3-b]thieno[3,2-e]- pyridine-2-carboxamides depending on steric hindrance in the amines. 相似文献