共查询到20条相似文献,搜索用时 15 毫秒
1.
A rapid and sensitive flow injection chemiluminescence method is described for the determination of sulfide based on the chemiluminescence generated during its reaction with either N-bromosuccinimide (NBS) or N-chlorosuccinimide (NCS) in alkaline medium. The results of investigation of the sensitized and non-sensitized chemiluminescence reactions are presented. The emission intensity is greatly enhanced for both NBS- and NCS-sulfide chemiluminescence systems if dichlorofluorescein (for NBS-sulfide) and fluorescein (for NCS-sulfide) are presented in the reaction solutions. The methods were applied satisfactorily to the determination of sulfide in spring water samples. 相似文献
2.
3.
A spectrophotometric flow injection system is described for the determination of hydrazine, involving oxidation of hydrazine by thallium(III) with concomitant formation of thallium(I). The optimum analytical conditions have been established. The linear range for hydrazine is 25-500 ng ml(-1) with a detection limit of 20 ng ml(-1). The sampling frequency is 40+/-5 samples h(-1). The relative standard deviation for 100, 250 and 500 ng ml(-1) is 3.5, 2.6 and 1.8%, respectively. The method has been applied to the determination of hydrazine in water. 相似文献
4.
5.
6.
7.
8.
9.
S. M. Sultan Aladdin M. Almuaibed A. Townshend 《Fresenius' Journal of Analytical Chemistry》1998,362(1):167-169
A new flow injection chemiluminescence method for the assay of medazepam is explored. The method involves the use of permanganate
in sulfuric acid for the oxidation of medazepam with the emission of chemiluminescence detected by a photomultiplier tube.
A simplex procedure was employed for optimising the conditions for high sensitivity detection, which were found to be 1.03
× 10–3 mol L–1 permanganate, 0.153 mol L–1 sulfuric acid and 3.43 mL min–1 flow rate. The linear calibration range was 3.7 × 10–5 to 1.7 × 10–3 mol L–1. The detection limit (3σ) and the sample throughput were 1.85 × 10–5 mol L–1 and 100 per hour, respectively. The relative standard deviation for 5 replicate determinations of 1.9 × 10–4 mol L–1 medazepam was 0.15%. Common excipients (starch, glucose, maltose, lactose) used in pharmaceutical preparations had no effect.
Received: 2 February 1998 / Revised: 20 May 1998 / Accepted: 25 May 1998 相似文献
10.
A simple chemiluminometric method using flow injection has been developed for the determination of paracetamol (acetaminophen), based on the chemiluminescence produced by the reduction of tris(2,2′-bipyridyl)ruthenium(III). The latter is obtained by oxidation of tris(2,2′-bipyridyl)ruthenium(II) by potassium permanganate in dilute sulphuric acid in the presence of paracetamol. A standard or sample solution was injected into the ruthenium(II) stream (flow rate 1.5 ml min−1) which was then merged with potassium permanganate in dilute sulphuric acid stream (flow rate 0.5 ml min−1). The chemiluminescence intensity is enhanced by the presence of manganese(II) ions. Under the optimum conditions, a linear calibration graph was obtained over the range of 0.3-50.0 μg ml−1 and the detection limit was 0.2 μg ml−1 (s/n = 3). The relative standard deviation of the proposed method calculated from 20 replicate injections of 5.0 μg ml−1 paracetamol was 1.1%. The sample throughput was 90 h−1. The method was successfully applied to the determination of paracetamol in commercial pharmaceutical formulations. 相似文献
11.
12.
13.
14.
Jiachu Huang Chengxiao Zhang Zhujun Zhang 《Analytical and bioanalytical chemistry》1999,363(1):126-128
A flow-injection chemiluminescence method for the determination of isoniazid based on the sensitizing effect of isoniazid on the chemiluminescence generating luminol-hypochlorite reaction is described. The hypochlorite was electrogenerated on-line by constant current electrolysis, thus, eliminating instability of hypochlorite solution prepared from commercially available sodium hypochlorite. The calibration graph is linear in the range 1 × 10–8 to 1 × 10–6 g mL–1, and the detection limit is 6 × 10–9 g mL–1. The relative standard deviation for determination of 5 × 10–8 g mL–1 is 2.8%. The proposed method has been successfully applied to the determination of isoniazid in pharmaceutical preparations. 相似文献
15.
16.
Flow injection chemiluminescence determination of isoniazid with electrogenerated hypochlorite 总被引:4,自引:0,他引:4
Jiachu Huang Chengxiao Zhang Zhujun Zhang 《Fresenius' Journal of Analytical Chemistry》1999,363(1):126-128
A flow-injection chemiluminescence method for the determination of isoniazid based on the sensitizing effect of isoniazid
on the chemiluminescence generating luminol-hypochlorite reaction is described. The hypochlorite was electrogenerated on-line
by constant current electrolysis, thus, eliminating instability of hypochlorite solution prepared from commercially available
sodium hypochlorite. The calibration graph is linear in the range 1 × 10–8 to 1 × 10–6 g mL–1, and the detection limit is 6 × 10–9 g mL–1. The relative standard deviation for determination of 5 × 10–8 g mL–1 is 2.8%. The proposed method has been successfully applied to the determination of isoniazid in pharmaceutical preparations.
Reveived: 2 May 1998 / Revised: 27 July 1998 / Accepted: 7 August 1998 相似文献
17.
流动注射-化学发光法测定头孢拉定 总被引:13,自引:0,他引:13
1 引 言头孢拉定 (cephradine ,CEP)是广泛用于临床治疗的一种头孢类抗生素药物。目前对其测定的主要方法有高效液相色谱法、分光光度计、荧光法和吸附极谱法等。利用Ce 与某些含巯基的化合物作用产生化学发光从而测定这些化合物的研究已有文献报道 ,但未见用于头孢拉定的测定。头孢拉定的降解产物含有巯基 ,本文采用流动注射技术考察了该降解产物与Ce 作用产生化学发光的条件 ,发现罗丹明 6G对该化学发光体系有很强的增敏作用 ,据此建立了测定头孢拉定的新方法。该方法用于胶囊中头孢拉定含量的测定 ,结果令人满意… 相似文献
18.
流动注射化学发光法测定氯化血红素 总被引:2,自引:0,他引:2
在甲醛存在的条件下,在酸性溶液中KMnO4与氯化血红素能够发生化学发光反应,产生很强的化学发光。据此采用流动注射技术,建立了一种利用KMnO4-甲醛-氯化血红素化学发光体系测定氯化血红素的化学发光分析法。方法的检出限为6×10-8g/mL;相对标准偏差为1.8%(2.0×10-6g/mL氯化血红素,n=11);线性范围为2.0×10-7~8.0×10-6g/mL。本法用于新鲜鸡血中氯化血红素的测定,结果与标准方法测得值一致。并对化学发光反应的机理进行了探讨。 相似文献
19.
流动注射化学发光法测定盐酸普萘洛尔 总被引:2,自引:0,他引:2
在酸性条件下,KMnO4氧化盐酸普萘洛尔可产生化学发光,Fe2 的存在对于这一化学发光反应具有增敏作用,基于此建立了测定盐酸普萘洛尔的化学发光分析法。在选定的实验条件下,盐酸普萘洛尔的质量浓度在4.0×10-7~1.0×10-5g mL范围内与化学发光强度具有线性关系(相关系数为0.9992),检出限为1×10-7g mL盐酸普萘洛尔,相对标准偏差为2.9%(4.0×10-6g mL盐酸普萘洛尔,n=11)。该法已用于盐酸普萘洛尔片剂中盐酸普萘洛尔的测定,并与药典方法进行了对照。 相似文献