The Reliability of Detection Limits in Analytical Chemistry

Abstract

Five guidelines were elucidated to be of importance in improving the reliability of detection limits in analytical chemistry. The necessity of following rigid statistical rules and documentation of the experimental system, the experimental parameters and the entire analytical procedure, is stressed, in order for the detection limits to have any reliability.     

新材料的发展与分析化学

文章介绍了新材料的重要性及发展方向,分析化学在新材料研制中起着耳目的作用,另一方面新材料也为分析化学的进展提供了课题与条件。微量分析、微区分析、表面分析是此领域中的重点。在未来的发展中,分析化学在材料的发展中的地位不会改变,并期待着分析灵敏度与空间分辩率的进一步提高。     

初中化学教材中拉瓦锡测定空气组成实验的探讨

查阅了相关史料，发现拉瓦锡测定空气组成实验的氧气含量测定值略小于1/6，而非教材所描述的约为1/5。质疑了文献中对该实验的解释，分析了原著中的实验现象和结论，对拉瓦锡的测定值为什么会小于真实值这一问题给出了新的解释。     

Nanomaterials and Analytical Chemistry

Abstract

Nanomaterials play an important role in the area of sensor technology. In fact the sensitivity and the signal‐to‐noise ratio of many chemical sensors are significantly improved using nanomaterials. They have allowed the introduction of many strategies in sensors and biosensor technology. Recently, catalytic nanomotors were used for drug delivery, showing an oriented motion into the cells when they are assembled using magnetic nanowires. In this review, detailed bibliographic references are presented concerning the assembling of nanomaterial‐based sensors, and a brief discussion about the potential health risk of nanoparticles will be also presented.     

Philosophy of Chemistry and Limits of Complexity

The problem of complexity is considered within the framework of concepts developed in recent studies in the philosophy of chemistry. According to previously expressed ideas about diminishing interactions (Vančik, 1999), as well as on the basis of the concept of levels of complexity, we speculate here that the complexity should approach its final limit. On the other hand, dynamical complexity may grow ad infinitum, and relativistic effects can only limit it. Impacts of these considerations on a possible change of actual paradigm of cosmology, especially on the anthropic principle, are also discussed. This revised version was published online in July 2006 with corrections to the Cover Date.     

分析化学进展

随着纳米材料、膜材料、有机功能材料、离子液体,以及光电技术、计算机科学的发展,分析化学在色谱、质谱、光谱、电分析等各分支领域都取得了重要进展。当然,分析化学的发展也有力地推动了我国的生命科学、材料科学、医学、生态与环境化学、矿产、食品安全等许多领域和学科的发展和进步。近年来,我国分析化学学科在与生命科学的学科交叉研究十分活跃,主要集中在蛋白质组学、代谢组学、金属组学中的新分析方法和新分析技术,例如纳米生物技术、生物传感器、微流控系统与芯片技术等,取得了一大批重要的研究成果。此外,针对食品安全、生态环境监测、药品检测、流行疾病应急响应等人们关注的热点开发了许多新的实用技术与方法;在大中型分析仪器的研发方面也取得喜人的进步。共引用97篇参考文献。     

Clinical Chemistry: Challenges for Analytical Chemistry and the Nanosciences from Medicine

Clinical chemistry and laboratory medicine can look back over more than 150 years of eventful history. The subject encompasses all the medicinal disciplines as well as the remaining natural sciences. Clinical chemistry demonstrates how new insights from basic research in biochemical, biological, analytical chemical, engineering, and information technology can be transferred into the daily routine of medicine to improve diagnosis, therapeutic monitoring, and prevention. This Review begins with a presentation of the development of clinical chemistry. Individual steps between the drawing of blood and interpretation of laboratory data are then illustrated; here not only are pitfalls described, but so are quality control systems. The introduction of new methods and trends into medicinal analysis is explored, along with opportunities and problems associated with personalized medicine.     

绿色化学理念下的无机及分析化学实验

根据理工类高等院校无机及分析化学实验课的特点, 结合基础化学实验中心实验条件, 从合理设置实验、减少试剂用量、取代有毒试剂、回收利用等方面对无机及分析化学实验进行了系列改革和实践, 使大部分实验实现了绿色化。减少了废渣、废液、废气对环境的污染, 降低了实验成本, 取得了良好的环境效益和经济效益。同时, 对学生进行了有效地绿色化学实践教育。     

Enzyme-Amplified Receptor Assay Predictive Model and Analytical Limits

Abstract

A theoretical basis for enzyme amplified receptor assay (ERA) is presented and criteria are established for the general case of any receptor system. Analytical criteria necessary to perform this assay are identified based upon the relevant affinity constants, the concentrations of the enzyme-labelled ligand and receptor, and the analyte.