(苯并-15-冠-5)双Schiff 碱的合成

由苯并-15-冠-5经硝化、还原两步反应,制得4',5'-二氨基苯并-15-冠-5(2)。后者与水杨醛或其取代衍生物缩合,合成了一系列新的冠醚化双Schiff碱化合物1a～1h,经元素分析、IR、^1^HNMR和MS确证了其结构。     

Tetrazole derivatives. 26. 2-Aryl-3-(p-dimethylaminophenyl)-5-phenyltetrazolium salts

Deeply colored tetrazolium salts were obtained by oxidation of triarylformazans containing a p-dimethylamino group in the N-phenyl substituent with bromine or nitrous acid.See [1] for communication 25.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 987–990, July, 1981.     

Synthesis and properties of 5-(5-nitro-2-furyl)thiazolines

The reactions of 2-amino-4-methyl-5-(5-nitro-2-furyl)thiazole with excess methyl iodide leads to 3,4-dimethyl-2-methylamino-5-(5-nitro-2-furyl)thiazolium iodide, which is converted to 2-imino-3,4-dimethyl-5-(5-nitro-2-furyl)thiazoline under the influence of bases. The iminothiazoline structure was proved by comparison of the spectral characteristics of its acetyl derivative and the isomeric 2-(N-acetyl-N-methyl) amino-4-methyl-5-(5-nitro-2-furyl)thiazole. The pKa values of 2-amino-4-methyl-5-(5-nitro-2-furyl)thiazole and 3,4-dimethyl-2-imino-5-(5-nitro-2-furyl)-thiazoline were determined, and the constant of the aminothiazole-iminothiazoline tautomeric equilibrium was calculated.Translated from Khimiya Geterosiklicheskikh Soedinenii, No. 10, pp. 1337–1340, October, 1985.     

4,7-Diphenyl-2-(p-dimethylaminophenyl)-1,3-indanedione and its dehydrodimer

Conclusions 4,7-Diphenyl-2-(p-dimethylaminophenyl)-1,3-indanedione is obtained by the Perkin-Gabriel reaction, with subsequent oxidation to the dehydrodimer.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 3, pp. 637–640, March, 1986.     

5,15-二苯基-10,20-二(2-吡啶基)卟啉的合成、表征及其晶体结构研究

本文采用丙酸法合成了新的5,15-二苯基-10,20-二(2-吡啶基)自由卟啉分子,并对其进行了MS,IR,UV-Vis,1H NMR及EA表征,探讨了合成过程中的注意事项及提高目标产物产率的方法。并利用溶剂挥发法得到了该卟啉分子的晶体,通过X-射线单晶衍射法确定了该化合物的晶体结构,结构分析表明该化合物属于单斜晶系,P21/c空间群。该化合物可用作构建金属有机框架材料(MOF)的配体。在波长为424 nm的光激发下,其最强发射峰位于655 nm,可以作为潜在的发光材料。     

Synthesis and liquid crystal properties of substituted 5-(arylcarbonyloxy)-2(p-cyanophenyl)pyrimidines

Liquid crystal p-substituted benzoates, biphenylcarboxylates, and benzoyloxybenzoates were obtained on the basis of 5-hydroxy-2-(p-cyanophenyl)pyrimidine. The development of nematogenicity by the esters due to the p-cyanophenyl grouping was noted, and the appearance of the smectic mesophase by the variation of the ring framework of the acid fragment of the molecule was investigated.Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences (RAN), Novosibirsk 630090. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 371–376, March, 1995. Original article submitted December 19, 1994.     

Synthesis and properties of 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-5-nitroindazole

N-(2-Azido-5-nitrobenzylidene)-3,5-di-tert-butyl-4-hydroxyaniline (3a) and N-(2-azido-5-nitrobenzilidene) aniline (3b), when heated in dimethylformamide yielded 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-5-nitroindazole (4a) and 2-phenyl-5-nitroindazole (4b), respectively. The structure of4b was confirmed by X-ray analysis. A stable phenoxyl radical was shown to originate from the oxidation of4a with lead (IV) dioxide.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 6, pp. 1095–1097, June, 1994.     

Synthesis and characterization of (Z)-5-arylmethylidene-rhodanines with photosynthesis-inhibiting properties

A series of rhodanine derivatives was prepared. The synthetic approach, analytical and spectroscopic data of all synthesized compounds are presented. Lipophilicity of all the discussed rhodanine derivatives was analyzed using the RP-HPLC method. The compounds were tested for their ability to inhibit photosynthetic electron transport (PET) in spinach (Spinacia oleracea L.) chloroplasts and reduce chlorophyll content in freshwater alga Chlorella vulgaris. Structure-activity relationships between the chemical structure, physical properties and biological activities of the evaluated compounds are discussed. For majority of the tested compounds the lipophilicity of the compound and not electronic properties of the R1 substituent were decisive for PET-inhibiting activity. The most potent PET inhibitor was (5Z)-5-(4-bromobenzylidene)-2-thioxo-1,3-thiazolidin-4-one (IC(50) = 3.0 μmol/L) and the highest antialgal activity was exhibited by (5Z)-5-(4-chlorobenzylidene)-2-thioxo-1,3-thiazolidin-4-one (IC(50) = 1.3 μmol/L).     

四(4-硝基苯基)卟啉和四(4-氨基苯基)卟啉的合成

四（４氨基苯基）卟啉（ＴＡＰＰ）是含有４个反应活性基团的卟啉衍生物,可在模拟某些生物过程或氧化还原反应的树枝状或簇状分子中作为富电子中心,也可直接用来制备光电器件或作为光电功能聚合物的功能单体和交联剂,因此,ＴＡＰＰ的合成研究具有重要意义［１］．...     

Synthesis and properties of 2-amino-5-(5-nitro-2-furyl) thiazole derivatives

The hydrochlorides of the corresponding 2-aminothiazoles, which were converted to the free bases, were obtained by hydrolysis of 2-acylamino-5-(5-nitro-2-furyl) thiazoles. Reactions that take place at the amino group of 2-amino-5-(5-nitro-2-furyl)thiazoles are described.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1038–1041, August, 1985.     

Synthesis and properties of rhodium(III) porphyrin cyclic tetramer and cofacial dimer

Rhodium(III) porphyrin complexes, [Rh(4-PyT(3)P)Cl](4) (1) and [Rh(2-PytB(3)P)Cl](2) (2) (4-PyT(3)P = 5-(4-pyridyl)-10,15,20-tritolylporphyrinato dianion, 2-PytB(3)P = 5-(2-pyridyl)-10,15,20-tri(4-tert-butyl)phenylporphyrinato dianion), were self-assembled and characterized by (1)H nuclear magnetic resonance spectroscopy, infrared spectroscopy, and electron spray ionization-mass spectroscopy methods. The spectroscopic results certified that the rhodium porphyrin complexes 1 and 2 have a cyclic tetrameric structure and a cofacial dimeric structure, respectively. The X-ray structure analysis of 1 confirmed the cyclic structure of the complex. The Soret bands of both oligomers were significantly broadened by excitonic interactions between the porphyrin units, compared to those observed for a corresponding analogue of Rh(TTP)(Py)Cl (TTP = 5,10,15,20-tetratolylporphyrinato dianion, Py = pyridine). Stepwise oxidation of the porphyrin rings in the oligomers was observed by cyclic voltammetry. The oligomers 1 and 2 are very stable in solution, and they slowly undergo reactions with pyridine to give corresponding monomer complexes only at high temperatures (approximately 80 degrees C).     

Synthesis and properties of 2-(n-pyridinium)-4- and 5-aza-1,3-indandione betaines

2-(N-Pyridinium)-4- and -5-azaindandione betaines were synthesized by condensation of quinolinic or cinchomeronic anhydride with N-carboxymethylpyridinium betaine. Their corresponding hydrohalide salts, as well as the halides and methyl- and decylsulfates of the N-methyl derivatives, were obtained.Translated from Khimiya Geterotsiklicheskikh Soedineii, No. 12, pp. 1637–1641, December, 1980.     

氨基磺酸型卟啉及其金属配合物的合成与性质

本文合成了水溶性中位-四[邻-（3-磺酸基丙氨基）苯基]卟啉和中位-四[对-（3-磺酸基丙氨基）苯基]卟啉及相应的金属（M=Fe^2＋，Co^2＋，Ni^2＋，Cu^2＋，Zn^2＋）配合物。测定了以上卟啉衍生物在水中的溶解度随温度和pH值的变化关系、卟啉与金属的配合性能。     

二[2-氨基-4,5-(15-冠-5)苯基]二硒化合物的合成

近一二十年来，人们对含有Ｓｅ—Ｓｅ键的有机硒化合物表现出浓厚的兴趣，首先是因为这类化合物在有机合成的选择性方面具有高度专一性［１］，其次，它们在热或光的作用下易于发生均裂作用［２］，第三，人们认为在一些重要的生物过程中，这类化合物是一种很重要的中间体...     

Synthesis and properties of 1-(5-halo-1-uracilyl)-β-D-glucofuranuronic acids

1-(5-Halo-1-uracilyl)-2, 5-di-O-acetyl--D-glucofuranurono-6,3-lactones were obtained by condensation of 2,4-bis(trimethylsilyl)-5-halouracils with 1,2,5-tri-O-acetyl--D-glucofuranurono;-6, 3-lactone. The chemical transformations of these compounds were studied. The structure of the glucuronides was proved by the IR, UV, circular dichroism, and NMR spectra.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1532–1537, November, 1981.