Preparation of 1,1,2-trifluoro-2-trimethylsilylethylene

1,1,2-Trifluoro-2-trimethylsilylethylene can be readily prepared via the Cu(I)Br catalyzed silylation of the 1,1,2-trifluoroethenylzinc reagent with Me₃SiCl. The reaction is easily scaled-up, isolation of the trifluorovinylsilane is facile, and the procedure can be readily adapted to other trialkyl halosilanes.     

Reaction of alkyl 2-chloro-1,1,2-irifluoroethyl ethers with lewis acids

Ethyl 2-chloro-1,1,2-trifluoroethyl ether heated with boron trifluoride etherate gave ethyl fluoride and chlorofluoroacetyl fluoride. When heated with aluminum chloride, it afforded a mixture of ethyl fluoride, ethyl chloride, chlorofluoroacetyl fluoride, and chlorofluoroacetyl chloride. Treatment of the acyl halides with ethanol yielded ethyl chloro- fluoroacetate. Butyl and octyl 2-chloro-1,1,2-trifluoroethyl ethers gave directly butyl and octyl chlorofluoroacetates, respectively, under similar conditions.     

Kinetics of the gas-phase thermal decomposition of 1,1,2-trifluoro-2-trifluoromethylcyclopropane

The kinetics of the gas-phase thermal decomposition of 1,1,2-trifluoro-2-trifluoromethyl-cyclopropane to 2,3,3,3-tetrafluoropropene and CF₂ was studied in the temperature range of 539–604°K and with a total pressure of 17 to 300 torr of a 1:20 mixture of reactant and perfluoroethylene. Some runs were also made with the reactant only, with initial pressures of 0.2 to 20 torr. The reaction is first order, homogeneous, and the rate constants fit the following Arrhenius relationship: .     

Reaction of 1-fluoro-2-trifluoromethoxy-1,1,2-trichloroethane with fluorinating agents

Conclusions In the reaction of 1-fluoro-2-trifluoromethoxy-1,1,2-trichloroethane with different fluorinating systems, dehydrochlorination and fluorination products are formed. It is assumed that substitution of chlorine atoms by fluorine takes place by the elimination-addition mechanism.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 8, pp. 1885–1887, August, 1984.     

Synthesis of 3,3,3-trifluoropropionic and 4,4,4-trifluoro-2-ketobutyric acids

Trifluoroethyl cyclohexyl ketone ($\text{4}$) is prepared by acylation of difluoroethylene ($\text{2}$) with cyclohexanecarboxylic acid chloride ($\text{1}$), followed by Cl→F exchange with potassium fluoride in the presence of triethylbenzyl- ammonium chloride. Bayer-Villiger oxidation of ketone ($\text{4}$) with trifluoroperacetic acid gives cyclohexyl trifluoropropionate ($\text{5}$). 3,3,3-trifluoropropionic acid ($\text{6}$) is obtained by treatment of ($\text{5}$) with trimethylsilyl iodide. Condensation of 2,2,2-trifluorodiazoethane ($\text{7}$) with ethyl glyoxylate ($\text{8}$) gives mainly ethyl 4,4,4-trifluoro-2-ketobutyric acid ester ($\text{9}$) which leads after hydrolysis to the corresponding acid ($\text{12}$).     

Reaction of 2,2,3,3-tetrafluoropropyl dichloro-phosphite with 1,1,2-trichloro-1-nitrosoethane

Conclusions Depending on the reaction conditions, 2,2,3,3-tetrafluoropropyi dichlorophosphate and 1,1,2-trichloro-1-nitrosoethane give either O-chloromethylchloroformiminodichlorophosphate or O-chloromethylchloroformimino-O-2,2,3,3-tetrafluoropropylchlorophosphate.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 6, pp. 1422–1423, June, 1987.     

Reaction of N-tert-butyl-2-haloaldimines with thiolcarboxylic acids

Russian Journal of General Chemistry - The reactions of N-tert-butyl-2-chloroaldimine with thiolcarboxylic acids occurs along two pathways: nucleophilic substitution of chlorine in the primary...     

Reaction of Disodium Ethene-1,1-bis(thiolates) with 1,1,2-Trichloroethane

Russian Journal of Organic Chemistry - Previously unknown chloro-substituted 1,3-dithiolanes were synthesized by reaction of disodium 2-cyanoethene-1,1-bis(dithiolates) with 1,1,2-trichloroethane....     

Reaction of 3-aminoindole-2-carboxylic acids with diethyl acetylenedicarboxylate

-Carboline and indolo--carboline derivatives were obtained by reaction of the potassium salts of 3-aminoindole-2-carboxylic acids with diethyl acetylenedicarboxylate. A difference in the behavior of 3-aminoindole derivatives in the Michael reaction due to the nature of the substituent in the 5 position of the indole ring was established.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 82–84, January, 1977.     

Azides of N-substituted aziridine-2-carboxylic acids. Reaction with methyl esters of amino acids

The corresponding azide was obtained by nitrosation of 1-benzylaziridine-2-carboxylic acid hydrazide. Reaction of the azide with methyl esters of amino acids gave N-(1-benzyl-2-aziridinylcarbonyl)-substituted methyl esters of amino acids.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1350–1352, October, 1980.