共查询到20条相似文献,搜索用时 31 毫秒
1.
Vytautas Getautis Albina Stanisauskaite Rimgaile Degutyte Jolanta Stumbraite 《Monatshefte für Chemie / Chemical Monthly》2007,138(12):1293-1296
Summary. Intramolecular cyclization of N,N′-di(3-chloro-2-hydroxy)propyl-N,N′-diphenylbenzidine occurs to give bis-1,2,3,4-tetrahydroquinoline derivative 1,1′-diphenyl-1,2,3,4,1′,2′,3′,4′-octahydro-6,6′-biquinolinyl-3,3′-diol. 相似文献
2.
E. O. Chukhajian A. A. Khachatryan A. R. Gevorkyan H. A. Panosyan 《Chemistry of Heterocyclic Compounds》2009,45(4):426-429
In aqueous base medium p-bis{3-[N-(3-chlorobuten-2-yl)pyrrolidinio (piperidinio or morpholinio)]-propyn-1-yl}benzene dichlorides undergo a two-way
dehydrochlorination-cyclization reaction to form benzo[5,6-a:5′,6′-c]bis(2,2-tetramethylene- or -2,2-pentamethylene-4-methylisoindolinium) and benzo-[5,6-a:5′,6′-c]bisspiro(4-methylisoindoline-2,4′-morpholinium) dichlorides.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 546–549, April, 2009. 相似文献
3.
Hyun-Jung Lee Oh-Kyu Lee Yeong-Han Kwon Don-Ha Choi Ha-Young Kang Hyeon-Yong Lee Ki-Hyon Paik Hak-Ju Lee 《Chemistry of Natural Compounds》2006,42(4):415-418
Four known isoflavone glucosides have been isolated from the bark of Amorpha fruticosa, which is a traditional remedy plant,
for the first time. They were elucidated as 3′-hydroxy-4′-methoxyisoflavone-7-O-β-D-glucopyranoside (1), 4′,6-dimethoxyisoflavone-7-O-β-D-glucopyranoside (2), 4′-methoxyisoflavone-7-O-β-D-glucopyranoside (3), and 3′,5-dihydroxy-4′-methoxyisoflavone-7-O-β-D-glucopyranoside (4), based on the UV, FT-IR, EIMS, FABMS, HREIMS, and NMR (1H and 13C, DEPT, COSY, NOESY, HMQC, and HMBC) data.
Published in Khimiya Prirodnykh Soedinenii, No. 4, pp. 336–338, July–August, 2006. 相似文献
4.
When irradiated with UV light, 5-bromo-4-dibromoamino-3-phenylisothiazole is converted into 3,7-diphenylbisisothiazolo[4,5-b:4′,5′-e]pyrazine andN,N′-bis(5-bromo-3-phenylisothiazol-4-yl)diazene.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 957–959, May, 2000. 相似文献
5.
Synthesis, structures, and properties of spiro[6-azaperimidine-2,4′-cyclohexa-2′,5′-dien]-1′-one derivatives 总被引:1,自引:0,他引:1
V. N. Komissarov E. N. Gruzdeva L. P. Olekhnovich G. S. Borodkin V. N. Khrustalev S. V. Lindeman Yu. T. Struchkov V. A. Kogan V. I. Minkin 《Russian Chemical Bulletin》1997,46(11):1924-1930
The reaction of 5-amino-4-chloroquinolines with 4-amino-2,6-di-tert-butylphenol yielded derivatives of spiro[6-azaperimidine-2,4′-cyclohexa-2′,5′-dien]-1′-one, which exhibit photo-and thermochromic
properties in solutions. The structure of 2′,6′-di-tert-butyl-5,7,9-trimethylspiro[6-aza,-2,3-dihydroperimidine-2,4′-cyclohexa-2′,5′-dien]-1′-one was established by X-ray diffraction
study. The ring-chain isomerization of 2′,6′-di-tert-butyl-5,7-dimethyl-and 2′,6′-di-tert-butyl-5,7,8-trimethylspiro[6-aza-2,3-dihydroperimidine-2,4′-cyclohexa-2′,5′-dien]-1′-ones was studied by dynamic NMR spectroscopy.
Deceased.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2028–2034, November, 1997. 相似文献
6.
I. M. Chung H. Y. Park S. C. Chun J. J. Kim A. Ahmad 《Chemistry of Natural Compounds》2007,43(4):417-421
Three new compounds, 4-hydroxymethylene-7-(9,9,13-trimethylcyclohexyl)-heptanyl-3′,7′,7′-trimethylcyclohexa-2′,4′-dien-1′-oate
(1), 1-(n-hexadec-7-enoxy)-6-(n-octadecanoxy)-β-D-glucopyranoside (2), and (Z)-12-hydroxy-9-octadecenoic acid-12-β-D-glucopyranoside (3), along with the known compound hexacosanoic acid (4), were isolated and identified from the rice hulls of Oryza sativa. Their structures were elucidated by 1D and 2D NMR spectroscopic techniques (1H-1H COSY, 1H-13C HETCOR, DEPT) aided by EIMS, FABMS, HRFABMS, and IR spectra.
Published in Khimiya Prirodnykh Soedinenii, No. 4, pp. 344–347, July–August, 2007. 相似文献
7.
A new procedure was developed for the synthesis of 3,7-disubstituted bisisothiazolo[4,5-b:4′,5′-e]pyrazines from 3-substituted 4-dibromoamino-5-haloisothiazoles under UV irradiation.N,N′-Bis(5-haloisothiazol-4-yl)diazenes were obtained as by-products.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 7, pp. 1350–1352, July, 1999. 相似文献
8.
The intramolecular electrophilic substitution in 6-functionalized 1,3-dimethyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-diones was used for the synthesis of pyrimido[4′,5′:3,4]-pyrrolo[1,2-a]quinoxaline-8,10(7H,9H)-dione, pyrimido[4′,5′:3,4]pyrrolo[2,1-c][1,2,4]benzo-triazine-8,10(7H,9H)-dione, and 2H-pyrimido[4′,5′:3,4]pyrrolo[1,2-a]indole-2,4,11(1H, 3H)-trione derivatives.
Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 2180–2185, December, 2006. 相似文献
9.
Syntheses are given for previously unreported 4-chloro derivatives of 4H-thieno[3′,2′:5,6]- and 4H-thieno[2′,3′:5,6]pyrimido[1,2-b]isoquinolines and the reactions of these compounds with N- and S-nucleophiles were studied. The spectral characteristics
and biological activity of the positional isomers were compared. The electron spectra most clearly reflect the differences
related to the position of the sulfur atom in these quasiaromatic systems.
*For Communication 33, see [1].
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 619–630, April, 2009. 相似文献
10.
Flavonoids uncharacteristic of intact plants were isolated from callus tissue of Iris ensata and were identified as 5-hydroxy-4′-methoxyflavone, 5-hydroxy-3′-methoxyflavone, and 5-hydroxy-2′-methoxyflavone using PMR
and mass spectrometry. It was proposed that the lack of growth of callus tissue after changing cultivation conditions was
related to the inhibiting effect of these flavones on cell proliferation.
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Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 440–442, September–October, 2005. 相似文献
11.
A. I. Shif S. N. Lyubchenko O. Ya. Borbulevych O. V. Shishkin K. A. Lyssenko L. P. Olekhnovich 《Russian Chemical Bulletin》1999,48(1):139-146
Oxidation of 4,6-di-tert-butylpyrogallol gave two dimeric products instead of the expected 4,6-di-tert-butyl-3-hydroxy-1,2-benzoquinone (2). It was established by X-ray diffraction analysis that the first product has the structure
of tetra-tert-butyl-6, 10a-dihydroxy-1,2-dioxo-3,4a,7,9-1,2,4a, 10a-tetrahydrodibenzo-1,4-dioxine. From this it follows that compound 2
undergoes regio- and stereospecific dimerization according to the [2π+4π]-cycloaddition mechanism,viz, the hetero Diels—Alder reaction. The double intensities of the signals in the1H NMR spectrum are indicative of a symmetrical structure of the second product, 2,6,4′, 6′-tetra-tert-butyl-4,4′-dihyroxy-3,5,3′,5′-tetraoxo-4,4′-bi(cyclohexene), which is a racemate of enantiomers formed upon recombination
(r+r orl+l) of the intermediate of oxidation of pyrogallol, namely, of ther,l-stereogenic 3,5-di-tert-butyl-1-hydroxy-2,6-dioxocyclohex-3-enyl radical.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 139–146, January, 1999. 相似文献
12.
M. Madesclaire V. P. Zaitsev J. V. Zaitseva S. Kh. Sharipova 《Chemistry of Heterocyclic Compounds》2007,43(10):1325-1332
A synthesis is reported for (4R,5R)-and (4S,5S)-4-hydroxymethyl-5-(4-nitrophenyl)oxazolidin-2-ones and (1′R,4R)-and (1′S,4S)-4-[hydroxy(4-nitrophenyl)methyl]oxazolidin-2-ones from (1R,2R)-and (1S,2S)-2-amino-1-(4-nitrophenyl)-1,3-propanediols. The effect of the experimental conditions on the formation of these compounds
was studied.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1562–1570, October, 2007. 相似文献
13.
M. P. Yuldashev B. A. Muminova A. A. Drenin E. Kh. Botirov 《Chemistry of Natural Compounds》2007,43(1):34-36
The new flavone glucoside viscioside, luteolin-4′-O-β-D-galactopyranoside, in addition to the known flavonoids apigenin, luteolin, quercetin, cinaroside, luteolin-4′-O-β-D-glucoside, and isoquercitrin were isolated from the aerial part of Vicia subvillosa.
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Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 30–31, January–February, 2007. 相似文献
14.
Xi Yan Fuli Wu Yun Liu Jiamian Li Zebao Zheng Huiquing Yan Shufeng Si 《Frontiers of Chemistry in China》2006,1(3):315-319
A new water soluble compound trisodium 5,3′,5′-trisulfonate-2,3,4,4′-tetrahydroxy-deoxybenzoin (TTDB) was synthesized and
characterized by IR, UV, 1H NMR, and elemental analysis. The single crystal of TTDB was determined by X-ray single crystal diffraction. The scavenging
effect of compounds on hydroxy radicals was detected by fluorescent spectrophotometry. The electrochemical behavior of compounds
in nonaqueous solution DMF was carried out by means of cyclic voltammetry. The experimental result shows that the crystal
[C14H17Na3O18S3] belongs to monoclinic, space group C2/c with unit cell constants a = 1.4223(4) nm, b = 2.4327(8) nm, c = 1.3596(4) nm, α = 90°, β = 113.044(5)°, γ = 90°, Z = 8, V = 4.329(2) nm3, D
c = 1.925 mg/m3, F(000) = 2568, F
w = 638.43, R
1 = 0.0950, wR
2 = 0.2648. The half effective concentration EC50 of scavenging hydroxy radicals of compound THDB is 53.1 μmol/L, while that of scavenging hydroxy radicals of compound TTDB
is 47.3μmol/L. The electrochemistry redox processes of THDB and TTDB are different from each other.
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Translated from Chemical Journal of Chinese Universities, 2005, 26(9) (in Chinese) 相似文献
15.
O. Ya. Borbulevych M. Yu. Antipin O. V. Shishkin V. N. Knyzev 《Russian Chemical Bulletin》2000,49(3):452-459
The electron density distribution in the crystal of the Meisenheimer complex of potassium 3-methyl-5′, 7′-dinitro-5′, 8′-dihydrospiro(1,3-oxazolidine-2,8′-
quinolinide) (1) was studied based on the data of precision X-ray diffraction study. The experimental data were compared with the results
of quantum-mechanical calculations. The electron density distributions in the regions of the nitro groups are substantially
different in spite of the similarity in the geometric parameters of these groups. In addition, there is a discrepancy between
the exprimental and theoretical data on this distribution. The effect of the cation on the electronic strucure of the anion
in the crystalline phase is the most probable cause of the differences observed. To reveal this effect.ab initio calculations of different anion1-K+ systems were performed and a topological analysis of the electron density distributions was carried out. Depending on the
mode of coordination of the cation to the anion, the former determines the contribution of alternative resonance forms to
the structure of the anion.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 3, pp. 451–458, March, 2000. 相似文献
16.
Svetlana I. Gramatikova Philipp Christen 《Applied biochemistry and biotechnology》2000,83(1-3):183-193
Cofactors—i.e., metal ions and coenzymes—extend the catalytic scope of enzymes and might have been among the first biological
catalysts. They may be expected to efficiently extend the catalytic potential of antibodies. Monoclonal antibodies (MAbs)
against Nα-phosphopyridoxyl-l-lysine were screened for 1) binding of 5′-phosphopyridoxyl amino acids, 2) binding of the planar Schiff base of pyridoxal-5′-phosphate
(PLP) and amino acids, the first intermediate of all PLP-dependent reactions, and 3), catalysis of the PLP-dependent α, β-elimination
reaction with β-chloro-D/L-alanine. Antibody 15A9 fulfilled all criteria and was also found to catalyze the cofactor-dependent
transamination reaction of hydrophobic D-amino acids and oxo acids (k′
cat=0.42 min−1 with D-alanine at 25°C). No other reactions with either D- or L-amino acids were detected. PLP markedly contributes to catalytic
effecacy—it is a 104 times more efficient acceptor of the amino group than pyruvate. The antibody ensures reaction specificity, stereospecificity,
and substrate specificity, and further accelerates the transamination reaction (k′
cat(Ab)/k′
cat(PLP)=5×103). The successive screening steps simulate the selection criteria that might have been operative in the evolution of protein-assisted
psyridoxal catalysis. 相似文献
17.
S. M. Ramsh A. G. Ivanenko V. A. Shpilevyi N. L. Medvedskiy P. M. Kushakova 《Chemistry of Heterocyclic Compounds》2005,41(7):921-928
Alkaline hydrolysis of 3-tert-butyl-7,7-bis(hydroxymethyl)-3,4-dihydro-2H-thiazolo[3,2-a][1,3,5]-triazin-6(7H)-one can occur in three directions: with cleavage of the tetrahydrotriazine ring, with cleavage of the
thiazolidine ring, and also with opening of both rings. Depending on the process conditions, either the hydrolysis product
corresponding to the first direction or the hydrolytic decomposition products corresponding to the second and third directions
can be obtained in preparative quantities. Hydrolysis of 3,3′-di-tert-butyl-3′,4′-dihydro-2′ H-spiro[(perhydro-1,3-oxazine)-5,7′-thiazolo[3,2-a][1,3,5]triazin]-6′-one in (NH4)2CO3 solution occurs in two steps: in the first step, cleavage of the tetrahydrotriazine ring occurs; and in the second step,
opening of the perhydrooxazine ring occurs.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 1089–1097, July, 2005. 相似文献
18.
E. V. Zhernosek S. V. Kvach L. A. Eroshevskaya E. N. Kalinichenko A. I. Zinchenko 《Chemistry of Natural Compounds》2006,42(2):208-211
Previously undescribed conjugates of 2′,3′-dideoxyuridine-5′-monophosphate-(L)-methoxytryptophylphosphoramidate (5) and 2′,3′-dideoxycytidine-5′-monophosphate-(L)-methoxytryptophylphosphoramidate (7) were isolated by a chemical enzymatic method in order to study their pharmacological properties and to prepare new medicinal
preparations based on them.
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Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 173–175, March–April, 2006. 相似文献
19.
Ge Zhang Mei-Li Guo Run-Ping Li Ying Li Han-Ming Zhang Zhong-Wu Su 《Chemistry of Natural Compounds》2009,45(3):398-401
A novel compound, 4-{1′-hydroxy-1′-mercapto-1′-[1′′-2′′(N→O)-isoquinolyl]}yl-1-benzoic acid (1), together with six known compounds, 6-hydroxykaempferol-3-O-β-D-glucopyranoside (2), rutin (3), quercetin-3-O-β-D-glucopyranoside (4), kaempferol-3-O-β-D-glucopyranoside (5), cartormin (6), hydroxysafflor yellow A (7), were isolated by chromatography from the n-BuOH fraction of 50% ethanol extraction of Flos carthami. Their structures were
elucidated on the basis of spectral analysis and comparison with published data. Among them, compound 1 was shown to possess a weak protective effect against cerebral ischemic damage in rats.
Published in Khimiya Prirodnykh Soedinenii, No. 3, pp. 339–341, May–June, 2009. 相似文献
20.
Thiocarbamoylation of 5-aminosalicylic acid with tetramethylthiuram disulfide afforded 5-(N′,N′-dimethylthioureido)salicyclic acid. Treatment of the latter with mineral acids or Ac2O gave 5-isothiocyanatosalicylic acid whose reaction with ethanolamine yielded 5-[N′-(2-hydroxyethyl)thioureido]salicylic acid. The latter underwent cyclization under the action of TsOH to form 5-(2-thiazolin-2-ylamino)salicylic
acid.
For Part 2, see Ref. 1.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 2315–2318, December, 1999. 相似文献