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Sen Xiang CHENG Li Min WANG Jun Biao CHANG? Ling Bo QU Rong Feng CHEN * Jing Xi XIE Department of Chemistry Zhengzhou University Zhengzhou Henan Research Center Henan Academy of Sciences Zhengzhou 《中国化学快报》2005,(2)
Schizandra chinesis(wuweizi)has long been used in Chinese herbal medicine.Schisandrin C,as a constituent of Schizandra chinesis,shows various pharmacologicalactivities1.The similar compound,dimethyl-4,4′-dimethoxy-5,6,5′,6′-dimethenedi-oxy-biphenyl-2,2′-dicarboxylate(α-DDB),discovered by Xie2,3et al.in the investing-ation of schisandrin C,and some derivatives have also exhibited anti-HIV and anti-HBVactivity4.Further study of this kind of biphenyls has attracted considerable attenti… 相似文献
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A facile procedure for the synthesis of 3-(2′-amino-3′-cyano-4′-arylpyrid-6′-yl)coumarins are being reported starting from 3- acetylcoumarin,aromatic aldehydes and malononitrile.The reactions were carded out on microwave irradiation in good yield with short time and easy work-up.The structures of all the compounds have been confirmed on the basis of their analytical,IR,~1H NMR, and mass spectral data. 相似文献
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用水热法合成了2个化合物[M2(L)(phen)2(H2P)2]·6H2O[M=Ni(1),Zn(2),H4L=4,4'-联吡啶-2,2',6,6'-四羧酸,phen=1,10-邻菲咯啉],并进行了元素分析、IR及X-射线单品结构测定等表征.晶体结构解析结果表明:配合物1和2的晶体都属于三斜晶系,P1空间群.配合物的中心金属离子都是六配位变形的八面体配位构型,配体4,4'-联吡啶-2,2',6,6'-四羧酸的羧基均以单齿形式配位.室温固体荧光测试结果显示配合物2具有较强的荧光. 相似文献
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Uranium(Ⅵ) complex {[UO2((R,S)-1,1′-biphenyl-6,6′-dinitro-2,2′-dicarboxylate)(H2O)](H2O)} was obtained by the hydrothermal treatment of UO2(NO3)2·6H2O with (R,S)-6,6′-dinitro-biphenyl-2,2′-dicarboxylic acid(BSNCA) (L) in water at 180 ℃ in Pyrex tube. The crystal belongs to triclinic system, space group P1, with a=0.903 45(14) nm, b=1.024 43(16) nm, c=1.058 95(16) nm, α=90.411(3)°, β=112.934(3)°, γ=92.554(3)°. CCDC: 659613. 相似文献
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A. N. Perevoshchikova A. A. Gorbunov Yu. S. Rozhkova P. A. Slepukhin Yu. V. Shklyaev 《Russian Journal of Organic Chemistry》2014,50(4):513-517
The reaction of 1-(4-methoxyphenyl)-1-(1-methylcyclohexyl)ethanol with nitriles in concentrated sulfuric acid afforded 1′-substituted 6′-methoxy-4′,4′-dimethyl-4′H-spiro[cyclohexane-1,3′-isoquinolines] as a result of consecutive Wagner-Meerwein rearrangement and Ritter reaction. 相似文献
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Reaction of 6,6′dideoxy-6,6′di-iodo-1′,2,3,3′,4,4′-hexa-O-benzylsucrose with triethyl phosphite afforded the corresponding 6,6′-diphosphonate. Selective phosphonylation either at the C-6 or 6-6′ position was also possible providing the corresponding sucrose mono-phosphonates. Reaction of 6,6′-dichloro-hexa-O-benzylsucrose with diphenylphoshine anion afforded the 6,6′-diphosphinosucrose. 相似文献
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IntroductionFunctional polymers bearing chiral moietiesand the extended conjugatedπ system have attract-ed considerable attention during the pastdecade[1,2 ] .The enantiodifferation properties ofsuch macromolecules give rise to multiple applica-tions in the fields of asymmetric catalysis,chiralsensors,polarized light emission and nonlinear op-tical materials[3 ,4] .Especially the incorporation ofoptically active binaphthyls in the main chain ofconjugated polymers can lead to an efficient ands… 相似文献
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YU Zhao-Lian LI Sen-Lan GUO Jin-Bo CHEN Qing-Hua② 《结构化学》2005,24(1):94-98
1INTRODUCTIONThecyclopropane-containingnaturalproductshavereceivedconsiderableattentionassynthetictar-getsastheincorporationofrigidifiedcyclopropylmotifintobioactiveanaloguescanleadtoconfor-mablyconstrainedmolecules[1,.Suchmodifica-2]tionsareexpectedtohavesignificanteffectsonbio-activitieswithconcomitantmedicalimplications.Des-pitethegreatadvancesinthisfield,theefficientsyn-thesisofspiro-cyclopropanecompoundsstillremainsaconsiderablechallenge.Particularnoticeisthede-ficiencyinthepreviousm… 相似文献
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The preparation of 6,6′-dibromo-2,2′-bipyridine and 6-bromo-2,2′-bipyridine are described. The dibromo compound was prepared by way of an improved cuprate synthesis resulting in a 72% yield. The monobromo species was prepared from the dibromo compound by way of metal-halogen exchange in 88% yield. 相似文献
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Zhehui Zhao Apeng Wang Xiaoxi Zhang Shuang Yang Zhigang Luo Pingsheng Lei 《中国化学快报》2019,30(2):425-427
A new and facile procedure was developed to synthesize novel 5-0- (6′-O-modified)-desosamine 14-membered ketolides by adopting different protective strategies and comparing various glycosylation conditions. Two trichloroacetimidate donors, with Lev or Ac substituent groups at the C-6 position, were synthesized to couple with the erythronolide. Several novel 5-0- (6′-O-modified)-desosamine 14-membered ketolides were obtained to verify the utility of the method. 相似文献
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运用水热法合成了1个新的配合物[Ni(Phtpy)2](CH3COO)2(化合物1),(Phtpy=4′-苯基-2,2′∶6′,2″-三联吡啶),并通过X-射线单晶衍射方法确定了该化合物的晶体结构.结构分析表明化合物1属于三斜晶系,P-1空间群,晶胞参数a=0.905 60(8)nm,b=1.103 07(9)nm,c=2.020 14(15)nm,α=94.383 0(10)°,β=100.983 0(10)°,γ=106.312 0(10)°,V=1.883 1(3)nm3,Z=2,R1=0.087 2,wR2=0.183 1.配合物中存在3种氢键和多种π-π相互作用,使其成为一个3D配合物. 相似文献
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George P. Rizzi 《合成通讯》2013,43(14):1173-1179
A wide variety of 2′-hydroxypolymethoxyacetophenones and propiophenones, e.g. 1a and 1b are used in the synthesis of flavone and ehromone natural products.1 Repeated attempts to prepare 1a and 1b by reacting 1,2,3,5-tetramethoxybenzene 2 with acetyl or propionyl chlorides and AlCl3 in ether2 gave products which were difficult to purify.3 We traced the problem to ring-ethoxy contaminants which were isolated and tentatively identified as 3a and 3b. 相似文献
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Two series of solid complexes of rare earth nitrates and picrates with the “back-to-back” terpyridine, 6′,6″-bis(2-pyridyl)-2,2′:4′,4″:2″,2′′′-quaterpyridine (L) have been synthesized. These complexes have been characterized by elemental analysis, conductivity measurements, thermal analysis and IR spectroscopy. At the same time, the luminescent properties of the Eu(Ⅲ) and Tb(Ⅲ) complexes were also studied. 相似文献
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[4,4′-bpyH_2][4,4′-bpyH][Cr(OH)_6(Mo_6O_(18))]和[4,4′-bpyH]_3[Al(OH)_6(Mo_6O_(18))]·2H_2O的合成及晶体结构(英文)
通过水热方法合成了两种新的B-Anderson型多钼氧酸盐[4 ,4′-bpyH2][4 ,4′-bpy H][Cr( OH)6( Mo6O18)](1)和[4 ,4′-bpyH]3[Al(OH)6( Mo6O18)].2 H2O(2) ,通过元素分析、IR光谱和单晶X射线衍射对其进行了表征.化合物1和2都是分离结构.化合物1分子由2个晶体学独立1/2 B-Anderson类型[Cr(OH)6( Mo6O18)]3 -多阴离子,1个双质子化的[4 ,4′-bpyH2]2 +阳离子和1个单质子化的[4 ,4′-bpyH]+阳离子组成,化合物2则是由1个晶体学独立完整的B-Anderson型[ Al( OH)6( Mo6O18)]3 -多阴离子, 3个单质子化的[4 ,4′-bpyH]+阳离子和2个晶格水分子组成.借助4 ,4′-bpy分子间的π-π堆积作用,化合物1和2形成三维超分子结构. 相似文献
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Yu Xin LI Zheng Ming LI Wei Guang ZHAO Wen Li DONG Su Hua WANG State Key Laboratory of Elemento-Organic Chemistry Nankai University Tianjin 《中国化学快报》2006,17(2)
Some 1-arylsulfonylthiosemicarbazides have been reported as fungicides1 and bacterio-static agents2. Recently, it is well documented that thiosemicarbazide is a novel class ofnon-peptide antagonists for bradykinin B2 , which is beneficial in the symptomat… 相似文献
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3′-Formyl-4′,6′-dihydroxy-2′-methoxy-5′-methylchalcone (FMC) was a natural product isolated from Cleistocalyx operculatus. A four-step synthetic strategy toward FMC and its four analogues (1b–1e) was first developed. All compounds were synthesized from commercially available 2,4,6-trihydroxyacetophenone; formylation at 3′ position under Vilsmeier–Haack conditions was followed by the introduction of a methyl group at 5′ position. The key step of selective methylation at 2′ position was achieved by trimethylsilyldiazomethane (TMSCHN2). Then substituted aromatic aldehydes were condensed through Claisen–Schmidt reaction in the presence of potassium hydroxide. All structures were confirmed by 1H NMR, 13C NMR, and high-resolution mass spectra. FMC and analogues were screened for their antiproliferative activity. 相似文献