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A Facile Method for the Synthesis of Benzoxazoles The preparation of benzoxazoles by a facile one-pot reaction is reported. The reaction of carboxylic acids with 2-chloro-N-methyl-Δ1-pyrrolinium chloride in an excess of N-methyl-2-pyrrolidone afforded carboxylic acid chlorides which were converted subsequently to their 2-hydroxyanilides by addition of 2-aminophenols. Cyclization of the 2-hydroxy-anilides at elevated temperatures furnished the benzoxazoles in high yield and purity.  相似文献   

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A New Facile Method for the Dealkylation of Phosphonic and Phosphinic Acid Esters The synthesis of phosphonic and phosphinic acid esters of the type is realized by reaction of dialkylphosphonates and O-alkylphosphinates with chlorotrimethylsilane in the presence of catalytical amounts of NH4Cl and hexamethyldisilazane (HMDZ).  相似文献   

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