A convenient synthesis of diacyl sulfides using a novel sulfur transfer reagent

Various diacyl sulfides were synthesized by reaction of acyl chlorides with LiAlHSH. Reaction of glutaryl chloride with LiAlHSH afforded glutaric thioanhydride. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:633–635, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10217     

Synthesis of N‐aryl S‐alkylthiocarbamates

Several N‐aryl S‐alkylthiocarbamates were synthesized by reactions of isocyanates with LiAlHSH and then with alkyl halides. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:374–378, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10163     

Reaction of nitrile oxides with vinylphosphonate: A facile,regioselective approach to 5‐phosphonyl‐4, 5‐dihydroisoxazoles

A series of 5‐phosphonyl‐4,5‐dihydroisoxazoles was synthesized from nitrile oxides and diethylvinylphosphonate under very mild conditions in good yields. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:254–257, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10136     

Conversion of 2(3H)‐furanones into 1,3,4‐oxadiazoles

A series of 2‐phenyl‐5‐alkenyl‐1,3,4‐oxadiazoles were synthesized in high yields from the corresponding dicarbonylhydrazides through cyclodehydration. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:570–574, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10197     

Oxidative cyclization in the synthesis of 5‐ and 6‐membered N,O‐heterocycles

The versatility and potential of oxidative cyclization in the synthesis of 5‐ and 6‐membered N‐ and/or O‐heterocycles is presented through judiciously selected examples.© 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:642–670, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10200     

Photodesulfurization of 2,4‐diaryl‐1,2, 4‐triazole‐3‐thiones

Irradiation of triazole thiones in thin‐film reactor furnished the corresponding desulfurized triazoles in good yield. The required triazole thiones were synthesized from the respective acid hydrazide and isothiocyanate. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:269–272, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10140     

Convenient synthesis of bisphosphonomethylphosphoric acid

The reaction of phosgene or triphosgene with trimethylsilyl dialkylphosphites led to bisdialkylphosphonomethyl‐dialkylphosphates in good yields. The cleavage of the allyl ester was carried out under mild conditions using the Wilkinson catalyst. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:111–113, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10105     

Studies on reactivity of ketosulfones

The cycloaddition of diazomethane, cyclocondensation of hydrazine hydrate, and cyclopropanation of TMSOI to 1‐aroyl‐2‐styrylsulfonylethenes were studied and different novel products thereby obtained were characterized with spectral parameters. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:155–159, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10117     

Selective phosphorylation of dihydroquercetin with trivalent phosphorus reagents

Characteristic features of phosphorylation of dihydroquercetin with trivalent phosphorus reagents were studied. Preparative methods for regioselective phosphorylation were found. The most important chemical properties of dihydroquercetin phosphites and cyclophosphites were studied. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:399–403, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10115     

Synthesis of novel thia‐oxadiazolophanes

The novel thia‐1,3,4‐oxadiazolophanes were synthesized regioselectively from 1,4‐bis(5‐mercapto‐1,3,4‐oxadiazol‐2‐yl)butane and various 1,ω‐dihaloalkanes in presence of potassium hydroxide. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:273–275, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10141     

Cycloaddition of bis‐1,3‐dipolar reagents to 1,3‐diarylprop‐2‐en‐1‐ones

Bis pyrazolines and isoxazolines were prepared by 1,3‐dipolar cycloaddition of benzene‐1,3/1,4‐dicarboxaldehyde dihydrazones and dioximes to 1,3‐diaryl‐prop‐2‐en‐1‐ones. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:379–383, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10169     

C‐phosphorylated pyrrolylcarbaldehydes

Application of N,N‐dimethylhydrazone protective group for synthesis of C‐phosphorylated aldehydes of the pyrrole series was studied. Removal of the hydrazone protection in monophosphorylated pyrrolylcarbaldehyde hydrazones occurs smoothly, while in biphosphorylated derivatives it results in nitrile formation. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:258–261, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10137     

A facile approach to phosphonic acid diesters

The symmetric H‐phosphonates of carbohydrate and other compounds were conveniently prepared by direct transesterification of the corresponding monohydroxylic compounds with diphenyl phosphite. The approach has the merits of mild reaction conditions and high yields. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:208–210, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10130     

Utility of a 2‐aminothiophene‐3‐carboxamide in the synthesis of thienopyridines and thienopyrimidines

2‐Amino‐4,5,6,7‐tetrahydrobenzo[b]‐ thiophene‐3‐carboxamide ( 1 ) was prepared according to Gewald procedure. Its reactivity toward a variety of chemical reagents was studied to give thienopyridines and ‐pyrimidines. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:459–467, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10179     

A Stepwise one‐pot synthesis of aryl N‐phosphonamidothionate derivatives of nucleosides

Novel aryl N‐phosphonamidothionate derivatives of nucleosides as membrane‐soluble prodrugs of bioactive free nucleotides have been prepared by phosphochloridothioate chemistry. Unprotected nucleosides, for example uridine and adenosine, were used; phosphorylation took place selectively at the 5′‐position. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:62–66, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10080     

M. Nath,S. Phokaria,X. Song,G. Eng,M. Gielen,M. Kemmer,M. Biesemans,R. Willem and D. de Vos, ‘New organotin(IV) derivatives of dipeptides as models for metal–protein interactions: in vitro anti‐tumour activity’ Applied Organometallic Chemistry 2003; 17(5): 305–314

The original article to which these Errata refer was published in the journal Applied Organometallic Chemistry 2003; 17 (5): 305–314. Copyright © 2003 John Wiley & Sons, Ltd.     

Phosphonylmethylaminocyclopentane‐1‐carboxylic acid

Phosphonylmethylaminocyclopentane‐1‐carboxylic acid was synthesized using Kabachnik–Fields reaction conditions in high yield and was characterized by NMR (¹H, ³¹P, and ¹³C) and FAB spectroscopy. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:229–230, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10124     

Cyclo[bis(1,7‐naphthylenedialkylamidophosphites)]

The possibility of regioselective cyclobisphosphorylation of nonsymmetrical bisphenols was shown for the 1,7‐dihydroxynaphthalene–phosphorous acid triamide system. The structure and essential chemical properties of the first nonsymmetrical phosphacyclophane were studied. New data demonstrating peculiar features of bisphenol diamidophosphites were obtained. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:404–412, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10143     

Synthesis of α‐aminophosphinates by the hydrophosphinylation of imines

Numerous substituted α‐aminophosphinates were synthesized by addition of alkyl and phenyl H‐phosphinates to aromatic imines and characterized. Modest diastereoselectivity was observed in the reaction. The size of the substituents exerts a small effect on the diastereoselectivity of P C bond formation. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:235–240, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10133     

Theoretical and synthetic approach to novel spiroheterocycles derived from isatin derivatives and L‐proline via 1,3‐dipolar cycloaddition

A cyclic secondary α‐amino acid, viz. L ‐proline, reacts with isatin derivatives via decarboxylative azomethine ylide formation and subsequent cycloaddition with various dipolarophiles to give cycloadducts in moderate to good yield. Theoretical studies have been performed to study the stereochemistry of the products formed. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:36–41, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10063