Novel Water Soluble Fluorescent Trimethine Indocyanines Containing N-p-Carboxybenzyl Group

Two fluorescent indocyanine dyes containing at least one p-carboxybenzyl group on the nitrogen atoms in the heterocyclic rings were designed and synthesized.Their absorption maxima were 549nm and 551nm in water respectively.They had good water solubility and photostability.     

Synthesis and Spectral Properties of Novel Water-soluble Near-infrared Fluorescent Indocyanines

Two fluorescent pentamethine and a squarylium indocyanines containing at least one p-carboxybenzyl group on N atoms in the heterocyclic rings were synthesized. They had good water solubility and photostability. Their maximum absorption and maximum emission were 600-700 nm in water. When it was anchored onto nanostructured TiO2 electrode, compared with in water, the squaraine showed double absorption peaks (one blue shifted and another red shifted) and absorption intensity of the red shift peak increased with the increase of the time of irradiation. The intensity of the blue one decreased simultaneously. We proposed that the presence of two electronic charge forms of squaraine anchored on the TiO2 film might be the reason.     

Syntheses and Biological Activities of Novel Benzotriazole Compounds Containing a Thioamide Group

IntroductionTriazoles(including benzotriazole)and their deri-vatives represent one of the most active classes of com-pounds possessing a wide spectrum of biological activi-ties.During the past several years,considerable evi-dence has been accumulated to d…     

Synthesis and Characterization of A Novel Cholesteric Liquid Crystalline Containing Carboxyl Group

A novel liquid crystal compound with a carboxyl group at one end, cholest-5-en-3-ol-(3β) hydrogen decanedioate (1) was successfuly prepared by the reaction of cholesterol with sebacoxl chloride. Its chemical structure and liquid crystalline properties were characterized by FTIR.CNMR,HNMR,POM and DSC. The compound with an active carboxyl group shows themortropic liquid crystalline behaviour.     

Novel Polyamides Containing Biphenyl-phthalazinone Moieties

Aromatic polyamides are characterized by the good mechanical strength and excellent thermal and oxidative stability but have limited solubility. Maintaining their thermal stability, considerable effort has been made towards the improvement of their solubility and processability through structural modification at the molecular level such as the introduction of bulky naphthalene moiety, an unsymmetric unit, a pendant group or a heterocycle moiety into the polymer backbone1~3. In this work, we re…     

Boron-Locked Starazine – A Soluble and Fluorescent Analogue of Starphene

A starlike heterocyclic molecule containing an electron-deficient nonaaza-core structure and three peripheral isoquinolines locked by three tetracoordinate borons, namely isoquinoline-nona-starazine (QNSA), is synthesized by using readily available reactants through a rather straightforward approach. This new heteroatom-rich QNSA possesses a quasi-planar π-backbone structure, and bears phenyl substituents on borons which protrude on both sides of the π-backbones endowing it with good solubility in common organic solvents. Contrasting to its starphene analogue, QNSA shows intense fluorescence with a quantum yield (PLQY) of up to 62 % in dilute solution.     

Synthesis, Structure and Biological Activities of Novel Triazole Compounds Containing 4,6-Dimethyl-pyrimidin-2-ylthio Group

Introduction As an important type of fungicides, triazole com-pounds are highly efficient, low poisonous and inward absorbent.1-3 At present, the studies on triazole deriva-tives are mainly concentrated on compounds with tria-zole as the only active group. The report on triazole compounds that contain both triazole group and other active group in a single molecule has rarely been found. Some pyrimidines have been used as highly efficient and lowly poisonous fungicides4 in controling powdery mi…     

Novel and Efficient Synthesis of Water‐Soluble [60]Fullerenol by Solvent‐Free Reaction

Abstract

Water‐soluble fullerenol was conveniently synthesized via the direct solvent‐free reaction of fullerene with a mixture of H₂O₂ and NaOH under grinding conditions in air at room temperature. This practical method provides a novel and efficient access to water‐soluble fullerenol in excellent yield.     

A Novel Chemo‐selective Epoxidation across Acrylate Ester: Synthesis of New Water‐Soluble Forskolin Analogues

While removing the TBDMS group from OH protection, a novel epoxidation reaction occurred across acrylate ester attached to a forskolin fragment. Besides spectroscopic data, the epoxide formation was confirmed by ring opening with a secondary amine. This unique epoxidation reaction, to our knowledge, is not known in the literature. This reaction led us to discover a simple deblocking protocol. The epoxide and the desired Michael substrates were used to introduce imidazole into forskolin.     

High-throughput Screening: Synthesis of a Novel Fluorescent Microspheres

As one of efficient analytes, fluorescent microspheres have shown much usability on many biochemical and biomedical processes. Recent applications with fluorescent microspheres have included cytokine quantitation, single nucleotide polymorphism genotyping, phosphorylated protein detection, and characterization of the molecular interaction of nuclear receptors. These, coupled with the rapid advances in molecular biology and synthesis techniques of drugs, have presented a basis for drug screenin…     

Novel Synthesis of N-Substituted p-Hydroxybenzoic Amides on Soluble Polymer-Support

The synthesis of N-substituted p-hydroxybenzoic amides using a liquid phase approach is described. Poly(ethylene glycol)(PEG) and p-hydroxybenzoic acid were linked by oxalyl chloride to give compound 1, which was chlorinated by thionyl chloride, followed by amidation with NHR^1R^2 to yield compound 3. Hydrolysis of compound 3 gave the title amide 4.These crude library members were obtained in good yields with high purities.     

Synthesis of a Novel Organic Soluble and Thermal-stable Fullerene-perylene Dyad

A novel organic soluble and thermal-stable fullerene-perylene dyad, in which a perylenemoietyis attached to C60, has been prepared by 1, 3-dipolar cycloaddition of the azomethine ylidesgenerated in situ from the aldehyde and N-methylglycine and characterized by NMR, FT-IR, TGA,absorption and fluorescent spectra etc.     

A Facile Synthesis of N-Phosphoryl Amino Acids Containing Hydroxy Group

three kinds of N-(diisopropyloxyphosphoryl) amino acids containing hydroxyl group were prepared in high yield by using diisopropyl phosphite as the phosphorylating agent, sodium hypochlorite as the chlorinating agent and tetrabutyl ammonium bromide as the phase transfer catalyst in basic aqueous media.     

Novel Blue Light-emitting PPV-based Copolymer Containing Triazole and Carbazole Units

For making the polymer light-emitting diode (PLED) device with good performance, it is desirable to reach the balance of electron and hole injection. However, for most conjugated polymer, hole injection is more favorable than electron injection. So it is important to design and synthesize the bipolar conjugated polymer with both electron and hole transporting ability for the fabrication of single-layer PLED1-2. In this communication we present the synthesis and preliminary characterizatio…     

Immobilization of Glucoamylase onto Novel Porous Supports Containing Cyclic Carbonate

Usually, before enzyme was immobilized onto support materials, these support materials had been activated through some activators, such as glutaraldehyde. The glucoamylase has been covalently immobilized onto several different support materials through the formation of Schiff base1-5. In this work, the glucoamylase was covalently (in the form of σ-bond) immobilized onto the porous polymer supports containing cyclic carbonate without activation. The relationship between the activity of the …     

Novel Bipolar Conjugated Polymer Containing Both Triphenylamine and Oxadizole Units

A novel bipolar conjugated polymer containing triphenylamine and 1,3,4-oxadiazole units was synthesized by Suzuki reaction.Its structure and properties were characterized by NMR,IR,UV-Vis,PL spectroscopy and electrochemical measurement. The photoluminescent spectroscopy and cyclic voltammograms measurement demonstrated that the resulting polymer shows blue emission (477 nm) and possesses both electron and hole-transporting property.     

Study on the Novel Dicyanate Ester Resin Containing Naphthalene Unit

The novel dicyanate ester resin containing naphthalene unit (DNCY) was synthesized,and characterized by FT-IR,^1H-NMR,^13C-NMR and elemental analysis (EA),The thermal properties of DNCY resin was studied by thermal degradation analysis at a heating rate of 10℃/min^-1 in N2 and air,The DNCY rdsin exhibited better thermal and thrmal-oxidative stability than bisphenol A dicyanate (BACY)resin.     

Synthesis and Characterization of a Novel Acrylonitrile Copolymer Containing Glucose Pendants

In this work,a novel sugar-containing copolymer was synthesized by the copolymerization of α-allyl glucoside(AG) with acryloniutrile(AN).The copolymers were characterized by NMR Spectroscopy.It was found that acrylonitrile-based copolymers containing as high as 22wt.% of α-allyl glucoside can be synthesized by the free radical solution copolymerization of the two monomers in DMSO with AIBN as initiator.     

Novel Fluorene-based Conjugated Copolymer Containing Cyclobutenedione Unit for Light Emitting Diodes

A novel fluorene-based conjugated copolymer containing cyclobutenedione unit was synthesized by Suzuki reaction.Its structure and properties were characterized by FTIR,^1HNMR,elemental analysis,PL spectroscopy,DSC,TGA and cyclic voltammetry.The resulting polymer shows strong yellow PL emission(561nm)and good solubility in polar aprotic solvents,i.e.THF,DMF,DMAC,DMSO,etc.DSC and TGA studies reveal that the novel polymer possesses excellent thermal stability with high glass transition temperature of 127℃ and onset decomposition temperature of 411℃.Cyclic voltammetry measurement demonstrated that the polymer has both hole and electron-transporting property.