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1.
N. F. Kirillov V. V. Shchepin V. S. Melekhin 《Russian Journal of Organic Chemistry》2007,43(11):1628-1631
Methyl 1-(2-bromo-2-methyl-1-oxopropyl)-, 1-(1-bromocyclopentylcarbonyl)-, and 1-(1-bromocyclohexylcarbonyl) cyclobutanecarboxylates reacted with zinc and aromatic aldehydes to give, respectively, 7-aryl-2,2-dimethyl-6-oxaspiro[3.5]nonane-5,9-diones, 11-aryl-12-oxadispiro[3.1.4.3]tridecane-5,13-diones, and 12-aryl-13-oxadispiro[3.1.5.3]tetradecane-5,14-diones. 相似文献
2.
Shchepin V. V. Kirillov N. F. Vakhrin M. I. 《Russian Journal of General Chemistry》2004,74(6):933-936
Methyl esters of 1-(1-bromocyclopentylcarbonyl)- and 1-(1-bromocyclohexylcarbonyl)cyclopentanecarboxylic or 1-(1-bromocyclopentylcarbonyl)cyclohexanecarboxylic acids react with zinc and aromatic aldehydes to form 14-aryl-13-oxadispiro[4.1.4.3]tetradecane-6,12-diones, 13-aryl-14-oxadispiro[4.1.5.3]pentadecane-6,15-diones, and 15-aryl-14-oxadispiro[4.1.5.3]pentadecane-6,13-diones, respectively. 相似文献
3.
N. F. Kirillov V. S. Melekhin M. I. Vakhrin 《Russian Journal of General Chemistry》2009,79(12):2652-2654
Methyl 1-(1-bromocyclohexylcarbonyl)cycloheptane- and 1-(1-bromocycloheptylcarbonyl)cyclohexanecarboxylates react with zinc
and aromatic aldehydes yielding 17-aryl-16-oxadispiro[5.1.6.3]heptadecane-7,15-diones and 15-aryl-16-oxadispiro[5.1.6.3]heptadecane-7,17-diones
respectively. 相似文献
4.
V. V. Shchepin Yu. G. Stepanyan P. S. Silaichev M. A. Ezhikova M. I. Kodess 《Russian Journal of Organic Chemistry》2010,46(4):499-502
Bromine-containing organozinc compounds generated from 1,1-dibromo-3,3-dimethylbutan-2-one reacted with 2-arylmethylideneindan-1,3-diones
and 5-arylmethylidene-2,2-dimethyl-1,3-dioxane-4,6-diones to give 3-aryl-2-(2,2-dimethylpropanoyl)spiro[cyclopropane-1,2′-indan]-1′,3′-diones
and 1-aryl-6,6-dimethyl-2-(2,2-dimethylpropanoyl)-5,7-dioxaspiro[2.5]octan-4,8-diones, respectively. Reactions of 2-arylmethylideneindan-1,3-diones
with bromine-containing zinc enolates derived from 1-aryl-2,2-dibromopropan-1-ones and 2,2-dibromo-1,2,3,4-tetrahydronaphthalen-1-one
resulted in the formation of 2-aroyl-3-aryl-2-methylspiro-[cyclopropane-1,2′-indan]-1′,3′-diones and 2,3: 8,9-dibenzo-12-phenyldispiro[4.0.5.1]dodecane-1,4,7-trione,
respectively. 相似文献
5.
N. F. Kirillov V. S. Melekhin D. V. Bogatyrev 《Russian Journal of Organic Chemistry》2008,44(7):1061-1063
Methyl 3-(1-bromocycloheptyl)-2,2-dimethyl-3-oxopropanoate and methyl 1-(2-bromo-2-methylpropanoyl)cycloheptanecarboxylates react with zinc and arylcarbaldehydes yielding 5-aryl-2,2-dimethyl-4-oxaspiro[5.6]dodecan-1.3-diones and 3-aryl-4,4-dimethyl-2-oxaspiro[5.6]dodecan-1.5-diones respectively. 相似文献
6.
Kirillov N. F. Shchepin V. V. Vakhrin M. I. 《Russian Journal of Organic Chemistry》2004,40(4):578-580
Methyl 1-(2-bromoisobutyryl)cyclopentanecarboxylate and 3-(1-bromocyclopentyl)-2,2-dimethyl-3-oxopropionate react with zinc and aromatic aldehydes to afford 8-aryl-9,9-dimethyl-7-oxaspiro[4.5]decane-6,10-diones and 10-aryl-7,7-dimethyl-9-oxaspiro[4.5]decane-6,8-diones, respectively. 相似文献
7.
V. V. Shchepin Yu. G. Stepanyan P. S. Silaichev 《Russian Journal of General Chemistry》2008,78(5):929-932
Organozinc compounds prepared from dialkyl dibromomalonates and zinc react with 2-arylmethyl-eneindan-4,6-diones, 5-arylmethylene-2,2-dimethyl-1,3-dioxane-4,6-diones, as well as with 2-[4-(1,3-dioxoindan-2-ylidenemethyl)phenyl]methyleneindan-1,3-dione and 5-[4-(2,2-dimethyl-4,6-dioxo-1,3-dioxane-2-ylidenemethyl)phenyl]methylene-2,2-dimethyl-1,3-dioxane-4,6-diones to form dialkyl 3-aryl-1′3′-dioxaspiro(cyclopropane-2,2′-indan)-1,1-dicarboxylates, dimethyl 3-aryl-6,6-dimethyl-5,7-dioxa-4,8-dioxaspiro[2,5]octan-2,2-dicarboxylates, dialkyl 2-{4-[3,3-bis (alkoxycarbonyl)-1′,3′-dioxaspiro(cyclopropane-2,2′-indan)-1-yl]phenyl}-1′,3′-dioxaspiro[cyclopropane-2,2′-indan]-1,1-dicarboxylates, and dialkyl 2-{4-[2,2-bis(alkoxycarbonyl)-6,6′-dimethyl-4,8-dioxo-5,7-dioxaspiro[2,5]oct-1-yl]phenyl}-6,6-dimethyl-4,8-dioxo-5,7-dioxaspiro[2,5]octan-1,1-dicarboxylate respectively. 相似文献
8.
V. V. Shchepin N. F. Kirillov V. S. Melekhin M. I. Vakhrin 《Russian Journal of General Chemistry》2006,76(9):1421-1422
Methyl 1-bromocyclohexanecarboxylate reacts with zinc in the presence of cyclobutanecarbonyl chloride to give methyl 1-(cyclobutylcarbonyl)cyclohexanecarboxylate. Bromination of the latter leads to the formation of methyl 1-(1-bromocyclobutylcarbonyl)cyclohexanecarboxylate which reacts with zinc and aromatic aldehydes, yielding 14-aryl-13-oxadispiro[3.1.5.3]tetradecane-5,12-diones. 相似文献
9.
Methyl 1-bromocyclohexanecarboxylate reacts with zinc in the presence of cyclohexanecarbonyl chloride to give methyl 1-(cyclohexylcarbonyl)cyclohexanecarboxylate. Treatment of the latter with bromine leads to formation of methyl 1-(1-bromocyclohexylcarbonyl)cyclohexanecarboxylate which reacts with zinc and aromatic aldehydes, yielding 16-aryl-15-oxadispiro[5.1.5.3]hexadecane-7,14-diones. 相似文献
10.
Alkyl 3-(1-bromocyclohexyl)-2,2-dimethyl-3-oxopropanoates react with zinc and aromatic aldehydes to yield 5-aryl-2,2-dimethyl-4-oxaspiro[5,5]undecane-1,3-diones. 相似文献
11.
T. V. Kochikyan E. V. Harutyunyan V. S. Harutyunyan A. A. Avetisyan 《Chemistry of Heterocyclic Compounds》2006,42(1):109-114
By reaction of 8-substituted 3-bromoacetyl-3,8-dimethyl-2,7-dioxaspiro[4,4]nonane-1,6-diones with thiourea and substituted
thioureas under Hansch reaction conditions, we have obtained the novel heterocycles 3-[2′-amino(arylamino)thiazol-4-yl]-3,8-dimethyl-2,7-dioxaspiro[4,4]nonane-1,6-diones.
By reacting the above-indicated bromoacetyl spirodilactones with 5-aryl-3-mercapto-1,2,4-triazoles, we obtained 8-substituted
3-(aryl-3,8-dimethyl-1′,2′,4′-triazol-3′-yl)thioacetyl-2,7-dioxaspiro[4,4]nonane-1,6-diones.
__________
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 123–129, January, 2006. 相似文献
12.
V. V. Khalturina Yu. V. Shklyaev Z. G. Aliev A. N. Maslivets 《Russian Journal of Organic Chemistry》2010,46(4):539-542
5-Arylfuran-2,3-diones react with (Z)-2-[3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene]acetamides to give (3E,5Z)-5-(2-aryl-2-oxoethylidene)-3-[3,3-dimethyl-3,4-dihydroisoquinolin-1(2H)-ylidene]-pyrrolidine-2,4-diones. The crystalline and molecular structures of one of the products were determined by X-ray
analysis. 相似文献
13.
N. N. Kolos E. N. Yurchenko V. D. Orlov S. V. Shishkina O. V. Shishkin 《Chemistry of Heterocyclic Compounds》2004,40(12):1550-1559
The interaction of arylbis(5,5-dimethylcyclohexane-1,3-dion-2-yl)methanes with o-phenylenediamine and o-aminophenol leads to the preparation of 3,3-dimethyl-11-aryl-2,3,4,5,10,11-hexahydrobenzo[b,e]-1,4-diazepin-1-ones and 3,3,6,6-tetramethyl-9-aryl-10-(2-hydroxyphenyl)-2,4,5,7,9-decahydroacridine-1,8-diones respectively. A one-pot method is proposed for the synthesis of derivatives of hexahydrodibenzo[b,e]-1,4-diazepin-1-ones. The structure of the first member of this series was confirmed by X-ray diffraction analysis.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1798–1808, December, 2004. 相似文献
14.
K. Praveen Kumar S. Satyanarayana P. Lakshmi Reddy G. Narasimhulu Narender Ravirala B.V. Subba Reddy 《Tetrahedron letters》2012,53(14):1738-1741
Iodine is found to be a highly efficient catalyst for the three-component coupling (3CC) of aldehydes, β-naphthol, and 1,3-dimethylbarbituric acid under solvent-free conditions to afford the corresponding 8,10-dimethyl-12-aryl-12H-naphtho[1′,2′5,6]pyrano[2,3-d]pyrimidine-9,11-diones in good yields with high selectivity. The use of readily available iodine makes this method very simple, convenient, and cost-effective. 相似文献
15.
V. V. Lipson S. M. Desenko M. G. Shirobokova O. V. Shishkin S. V. Shishkina 《Russian Journal of Organic Chemistry》2006,42(7):1022-1027
Cyclocondensation of 5-methylpyrazol-3-amine with methyl cinnamate and arylmethylidenemalonic acids in DMF and methanol leads to the formation of 7-aryl-2-methyl-6,7-dihydropyrazolo[1,5-a]-pyrimidin-5(4H)-ones. Arylmethylidenemalonic acids react with the title amine at a ratio of 1:2 in nitrobenzene to give 4-aryl-3,5-dimethyl-1,7-dihydrodipyrazolo[3,4-b:4′,3′-e]pyridines. Heterocyclizations of 5-methylpyrazol-3-amine with 5-arylmethylidene-2,2-dimethyl-1,3-dioxane-4,6-diones or their precursors, para-substituted benzaldehydes and 2,2-dimethyl-1,3-dioxane-4,6-dione (Meldrum’s acid) in all solvents (methanol, DMF, and nitrobenzene) give the corresponding 4-aryl-3-methyl-2,4,5,7-tetrahydropyrazolo[3,4-b]pyridin-6-ones. The structure of 3-methyl-4-(4-nitrophenyl)-2,4,5,7-tetrahydropyrazolo[3,4-b]pyridin-6-one was proved by X-ray analysis. 相似文献
16.
Shchepin V. V. Kirillov N. F. Nedugov A. N. 《Russian Journal of General Chemistry》2003,73(8):1264-1266
Methyl esters of 1-(-bromoisobutyryl)cyclohexanecarboxylic or 3-(1-bromocyclohexyl)-2,2-dimethyl-3-oxopropanoic acids react with zinc and arylglyoxals to form 3-aroyl-4,4-dimethyl-2-oxaspiro[5.5]undecane-1,5-diones or 1-aroyl-4,4-dimethyl-2-oxaspiro[5.5]undecane-3,5-diones, respectively. The former products react with phenylhydrazine, yielding 3-[aryl(2-phenylhydrazono)methyl]-4,4-dimethyl-2-oxaspiro[5.5]undecane-1,5-diones. 相似文献
17.
T. G. Simonova S. P. Epshtein Yu. G. Putsykin Yu. A. Baskakov 《Chemistry of Heterocyclic Compounds》1980,16(7):761-764
Treatment of 2-ethylamino-2-methylpropanol oxime with aryl isocyanates leads to 4-[N-(arylcarbamoyl) hydroxyamino [-1-ethyl-3-aryl-5,5-dimenthyl-2-imidazolidionones, which are acylated by acid chlorides and methyl isocyanate to give the corresponding O-acyl derivatives and are converted to 2-(2-oxo-1-ethyl-3-aryl-5,5-dimethyl-4-imidazolidinyl)-4-aryl-1,2,4-oxadiazolidine-3,5-diones by the action of methyl chlorocarbonate.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 980–983, July, 1980. 相似文献
18.
In this communication, we wish to report the synthesis of some new spiro-4-oxazolidinones. Treatment of the potassium salt of 2-methyl-cyclohexane-1,3-dione (1) with α-chloroacetanilides (2 a-c) gave 4-aryl-6-methyl-1-oxa-4-aza-spiro [4,5] deca-3,7-diones (3 a-c); and with α-halopropionanilides (2 d,e), the corresponding 4-aryl-2,6-dimethyl-1-oxa-4-aza-spiro [4,5] deca-3,7-diones (3 d, e) were obtained. 相似文献
19.
Liqiang Wu Yanfang Wu Fulin Yan Lizhen Fang 《Monatshefte für Chemie / Chemical Monthly》2010,14(4):871-875
Abstract
Three-component one-pot synthesis of some novel 12-aryl-12H-benzo[i][1,3]dioxolo[4,5-b]xanthene-6,11-diones involving treatment of 3,4-methylenedioxyphenol, aldehydes, and 2-hydroxy-1,4-naphthoquinone in presence of HClO4–SiO2 was achieved, and this reaction was extended to preparation of 10-aryl-6,7,8,10-tetrahydro-7,7-dimethyl-9H-[1,3]dioxolo[4,5-b]xanthen-9-ones by three-component reaction of 3,4-methylenedioxyphenol, aldehydes, and dimedone. 相似文献20.
Shchepin V. V. Sazhneva Yu. Kh. Russkikh N. Yu. Vakhrin M. I. 《Russian Journal of General Chemistry》2003,73(5):760-764
Zinc enolates of 3-alkyl-6-aryl-5,5-dimethyl-2,3,5,6-tetrahydropyrane-2,4-diones react with acyl chlorides to form O-acylation products, 4-acyloxy-3-alkyl-6-aryl-5,5-dimethyl-5,6-dihydropyrane-2-ones. Sodium enolates of these pyranediones react in DMSO with substituted benzyl bromides to give mainly C-alkylation products, 3-alkyl-6-aryl-3-(4-R-benzyl)-5,5-dimethyl-2,3,5,6-tetrahydropyrane-2,4-diones, as single geometric isomers. In some cases, O-alkylation products, 4-alkoxy-3-alkyl-6-aryl-5,5-dimethyl-5,6-dihydropyrane-2-ones, are formed as by-products (10-15%). 相似文献