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Background  

Narcolepsy causes dramatic behavioral alterations in both humans and dogs, with excessive sleepiness and cataplexy triggered by emotional stimuli. Deficiencies in the hypocretin system are well established as the origin of the condition; both from studies in humans who lack the hypocretin ligand (HCRT) and in dogs with a mutation in hypocretin receptor 2 (HCRTR2). However, little is known about molecular alterations downstream of the hypocretin signals.  相似文献   

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We show that it is possible to construct a supersymmetric mechanics with four supercharges possessing not conformally flat target space. A general idea of constructing such models is presented. A particular case with Eguchi-Hanson target space is investigated in detail: we present the standard and quotient approaches to get the Eguchi-Hanson model, demonstrate their equivalence, give a full set of nonlinear constraints, study their properties and give an explicit expression for the target space metric. Presented at the International Colloquium “Integrable Systems and Quantum Symmetries”, Prague, 16–18 June 2005.  相似文献   

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We confront different up to date cosmological data with different gravity models of the Universe with one additional massive sterile neutrino [1].  相似文献   

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By using heavy-ion induced fusion-evaporation reactions at the on-line mass separator of GSI, the decay properties of neutron-deficient isotopes between 56Ni and 100Sn were investigated. The experimental results will be presented and discussed in comparison with model predictions.  相似文献   

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We study the ground state phase diagram of the two dimensional tt′ — U Hubbard model concentrating on the competition between antiferro-, ferro-, and paramagnetism. It is known that unrestricted Hartree–Fock- and quantum Monte Carlo calculations for this model predict inhomogeneous states in large regions of the parameter space. Standard mean field theory, i.e., Hartree–Fock theory restricted to homogeneous states, fails to produce such inhomogeneous phases. We show that a generalization of the mean field method to the grand canonical ensemble circumvents this problem and predicts inhomogeneous states, represented by mixtures of homogeneous states, in large regions of the parameter space. We present phase diagrams which differ considerably from previous mean field results but are consistent with, and extend, results obtained with more sophisticated methods. PACS: 71.10.Fd, 05.70.Fh, 75.50.Ee  相似文献   

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For higher-derivative f(R) gravity, where R is the Ricci scalar, a class of models is proposed, which produce viable cosmology different from the ACDM at recent times and satisfy cosmological, Solar System, and laboratory tests. These models have both flat and de Sitter spacetimes as particular solutions in the absence of matter. Thus, a cosmological constant is zero in a flat spacetime, but appears effectively in a curved one for sufficiently large R. A “smoking gun” for these models would be a small discrepancy in the values of the slope of the primordial perturbation power spectrum determined from galaxy surveys and CMB fluctuations. On the other hand, a new problem for dark energy models based on f(R) gravity is pointed out, which is connected with the possible overproduction of new massive scalar particles (scalarons) arising in this theory in the very early Universe. The text was submitted by the author in English.  相似文献   

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The 4s-1s two-quantum decay in the hydrogen atom is calculated in the framework of quantum electrodynamics with allowance for cascades. It is shown that the pure two-photon contribution cannot be separated from the contribution of cascade processes. Interference between the transitions of these two types is comparable in magnitude with the pure two-photon contribution. The separation of pure two-photon contributions is discussed recently in connection with the role of two-photon decays in the separation of radiation from matter in the early Universe.  相似文献   

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The properties of polycrystalline CdTe with a grain size of 5–30 μm have been investigated using the microphotoluminescence methods of spectral analysis and topography. This material has been prepared by direct synthesis in a vapor flow of components at a low temperature. The dominance of the Y and Z bands in the spectra reflects a nonequilibrium character of the crystallization processes. The superlinear dependences of the luminescence intensity on the level of the band-to-band excitation indicate the exciton nature of the corresponding transitions. The activation energies for temperature quenching of luminescence in the temperature range T = 100–150 K are found to be 120 meV for the Y luminescence and 180 meV for the Z luminescence, which correspond to the dissociation of excitons bound to defects with the transition of charge carriers to the conduction and valence bands. The monochromatic topography data indicate that Y and Z defects have different material bases.  相似文献   

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The (1 + 1)-dimensional nonlinear O(3) σ model involving an explicitly broken symmetry is considered. Sphalerons are known to exist in this model. These sphalerons are of a topological origin and are embedded kinks of the sine-Gordon model. In the case of a compact spatial manifold S 1, sine-Gordon multikinks exist in the model. It is shown that the model admits a nonstatic generalization of the sine-Gordon kink/multikink, Q kink/multikink. Explicit expressions are obtained for the dependence of the Q kink energy and charge on the phase frequency of rotation. The Q kink is studied for stability, and expressions are obtained for the eigenfunctions and eigenfrequencies of the operator of quadratic fluctuations. It is shown that the Q kink is unstable over the entire admissible frequency range ω ∈ [−1, 1]. The one-loop quantum correction to the static-kink mass is calculated, and the Q-kink zero mode is quantized. It is shown that, in a general static case, the field equations of the model are integrable in quadratures.  相似文献   

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