Comparative study of MIRD,experimental and GEANT4 simulations for uniformly distributed I-131 in cylindrical and spherical thyroid models

Due to worldwide use of I-131 for the treatment of benign and malignant thyroid diseases, reliable dose estimation for various thyroid mass values is necessary. In this study computation of the radiation absorbed dose due to β- and γ-activity of I-131 to thyroid has been carried out using the GEANT4 code for water, ICRP and ICRU soft tissues simulating thyroid tissue. The results are validated by comparison with the MIRD calculations. The effect of size and shape of thyroid on absorbed dose has also been studied by varying the volume of thyroid in 10–150 cm³ range and by using spherical and cylindrical models for thyroid. Experimental measurements have also been performed using a group of 20 patients, who were treated for thyro-toxicosis with I-131. Dose equivalent was measured with a portable ionization chamber after the administration of 405–851 MBq of I-131. Comparison of peak energy and effective energy per transformation with the MIRD has been performed yielding only 0.5% relative differences between these two energies. For spherical model, the relative difference of peak and effective energies with the MIRD is 5.2% and 4.7% respectively and very similar for cylindrical models. Spherical model shows 0.45% increase as compared to that of cylindrical model. The use of water, ICRP or ICRU materials only implies negligible difference. Total energy deposition per decay of I-131 increases with volume for both models. The estimated results of spherical and cylindrical thyroid models show an excellent agreement with the corresponding the MIRD results. Simulated results for ambient dose equivalent rate show a good agreement with our experiment and corresponding errors remain less than 13% in the case of dose at 1 m, and are less than 8% for doses at the neck surface.     

First Observation of 131Pm Decay

¹³¹Pm nucleus was produced in the ¹⁰⁶Cd (³²S,3p4n) ¹³¹Pm reaction. Theproducts were transported by helium jet and tape system, and X,γ single spectra and X-γ,γ-γ coincidence spectra were measured. The half-life of ¹³¹Pm has beendetermined to be (6.3±0.8)s. A partial decay scheme of ¹³¹Pm is proposed.     

First Study of Weak (EC+β+) Decay Branch for the Neutron-Deficient Isotoep 209Fr

²⁰⁹Fr has been produced by irradiation of ¹⁹⁷Au with ¹⁶O from SFC accelarator uia the fusion-evaporation 4n channel.The(EC+β⁺)decay of ²⁰⁹Fr has been studied by a He-jet tape transport system.The decay scheme is proposed for the first time based on γ-t,X-γ-t,γ-γ-t coincidece and γ-γ delay coincidence measurements,which takes account of 20 observed γ ray.Five members of low-lying states in ²⁰⁹Rn can be explained by the multi-plet [(²¹⁰Rn2⁺)(νf_5/2)^－1].The branching ratio for(EC+β⁺) decay of ²⁰⁹Fr has been estimated experimentaly to be(3.0±1.5)%.     

β-Delayed Proton Decays of 133Sm and 149Yb

¹³³Sm was produced via fusion evaporation in the reaction ⁴⁰Ca+⁹⁶Ru. Its β-delayed proton decay was studied by means of “p-γ” coincidence in combination with a He-jet tape transport system, including half-lives, proton energy spectra, γ-transitions following the proton emissions, and the branching ratios to the low-lying states in the grand-daughter nuclei. The possible spins and parities of ¹³³Sm were extracted by fitting the experimental data with a statistical model calculation. The configuration-constrained nuclear potential energy surfaces of ¹³³Sm were calculated by using the Woods-Saxon Strutinsky method. Comparing the experimental and calculated results, the spins and parities of ¹³³Sm were assigned to be 5/2⁺ and 1/2^－, which is reconciled with our published simple (EC+β⁺) decay scheme of ¹³³Sm in 2001. In addition, our experimental data on the beta-delayed proton decay of ¹⁴⁹Yb reported in Eur. Phys. J., 2001, A12: 1—4 was also analyzed by using the same method. The spin and parity of ¹⁴⁹Yb was assigned to be 1/2^－.     

THE COULOMB DISINTEGRATION CROSS-SECTION AND DECAY RATE OF THE SPIN (0－3/2) ELECTROMAGNETIC BOUND SYSTEM

In this paper, the coulomb disintegration cross-section and decay rate of the atom (π⁺Ω^－) are calculated by using perturbation expansion of the quantized composite field theory and relativistic B-S wave function for spin (0－3/2) electromagnetic bound system. The disintegration cross-section of the high energy atom (π⁺Ω^－) in screened coulomb field of nuclei is about σ=Z^4/3×2.9×10^－18cm², and the calculation result of the decay rate is w[(π⁺Ω^－)→π⁺Λ⁰K^－]/w[Ω^－→Λ⁰K^－]=1+O(α).     

Contribution of One-Photon Annihilation at ψ(2S) in e+e－ Experiment

The continuum one-photon annihilation at ψ(2S) in e⁺e^－ experiment is studied. Such contributions to the measured final states ωπ⁰ and π⁺π^－ at ψ(2S) mass are estimated by phenomenological models. It is found that these contributions must be taken into account in the determination of branching ratios of ψ(2S)→ωπ0 and ψ(2S)→π⁺π^－, as well as other electromagnetic decay modes. The study reaches the conclusion that in order to obtain the correct branching ratios on these decay modes at BES, at least 10pb^－1of data below the ψ(2S) peak is needed.     

First Experimental Determination of Half-Life for New Nuclide 65Se

By using experimental data obtained from the measurement of beta-delayed proton decay of ⁶⁵Se produced in ⁴⁰Ca(²⁸Si,3n)reaction,the absolute detection efficiency of particle telescope for rotating radioactive source was imitatively calcu-lated.The half-life of ⁶⁵Se was thus accurately determined to be 9.6_-4.1^+5.3 ms.The β-delayed proton energy of ⁶⁵Se was 3.70±0.08MeV.The partial decay scheme of ⁶⁵Se β-delayed proton decay was revised and proposed.     

(EC+β+) decay of 130Pm and 128Pr

¹³⁰Pm and ¹²⁸Pr were produced by irradiation of ⁹⁶Ru with ³⁶Ar, and studied using a He-jet recoil tape transport system. Based on X-% and %-% coincidence measurements, the (EC+ # ⁺) decay scheme of ¹³⁰Pm was proposed for the first time and the (EC+ # ⁺) decay scheme of ¹²⁸Pr was revised.     

Radial excitation states of η and η' in the chiral quark model

A chiral quark model is applied to calculate the spectra of pseudoscalar mesons η and η'. By analyzing the obtained spectra, we find that the mesons η'(2¹S₀), η(4¹S₀), η'(3¹S₀) and η'(4¹S₀) are the possible candidates of η(1760), X(1835), X(2120) and X(2370). The strong decay widths of these pseudoscalars to all the possible two-body decay channels are calculated within the framework of the ³P₀ model. Although the total width of η'(2¹S₀) is compatible with the BES Collaboration's experimental value for η(1760), the partial decay width to ωω is too small, which is not consistent with the BES result. If X(1835) is interpreted as η(4¹S₀), the total decay width is compatible with the experimental data, and the main decay modes will be mπ a₀(980) and m π a₀(1450), which needs to be checked experimentally. The assignment of X(2120) and X(2370) to η'(3¹S₀) and η'(4¹S₀) is disfavored in the present calculation because of the incompatibility of the decay widths.     

Estimating equivalent doses of internal radiation for the alpha-emitting radiopharmaceutical Astatine-211

The integral activities of the α-emitting radiopharmaceutical (RP) Astatine-211 are estimated using empirical data on the pharmacokinetics when RP is introduced into the body. The obtained values are compared to the analogous estimates for RP 131I in isotonic solution. Linear energy losses are estimated for different organs and tissues of the human body. The linear quadratic model [1] is used to assess the relative qualitative biological effectiveness of α radiation from ²¹¹At. The Medical Internal Radiation Dose Committee (MIRDC) approach is used to analyze equivalent and effectively equivalent doses for the standard adult body.     

Emission of γ-quanta,electrons, and positrons upon the decay of <Superscript>12</Superscript>N and <Superscript>12</Superscript>B produced in characteristic targets

The emission of γ-quanta, electrons, and positrons upon the decay of ¹²N and ¹²B produced in characteristic targets is calculated within radiation–matter interaction models generated using the GEANT and MCNP simulation software.     

New Nuclide 129Pm Near the Proton Drip Line

The very neutron-deficient nuclide ¹²⁹Pm was produced via the ⁹²Mo(⁴⁰Ca, p2n) reaction and identified for the first time by using the X-γ coincidence in combination with a He-jet tape transport system. From the decay of a 99keV γ ray which corresponds to the 5/2^－→1/2^－ transition in the daughter nucleus ¹²⁹Nd following the (EC+β⁺) decay of ¹²⁹Pm, the half-life of ¹²⁹Pm was determined to be 2.4(6)s.     

Calculating specific absorbed fractions with standard Korean male adults

Based on data representing standard Korean male adults, a mathematical anthropomorphic phantom was developed to calculate the specific absorbed fraction for several organs. The results were then compared against values calculated with other phantoms (OTOKO of Japan, MIRD of the U.S. and GOLEM of Germany). We compared the specific absorbed fractions of six organs (the adrenals, kidneys, liver, lungs, pancreas and spleen) for two cases: when the source and target organs are the same, and when they are different. When both the source and target organs are the same the organ with the highest specific absorbed fraction regardless of energy level was found to be the adrenals in all phantoms. In comparing phantoms, the phantom developed on the basis of standard Koreans produced the highest specific absorbed fraction. Also, as a result of conducting an assessment by separating source organs from target organs, the phantom developed on the basis of standard Koreans displayed relatively high specific absorbed fractions although there were slight differences per organ.     

First principles study of nuclear quadrupole interactions in the molecular solid BF3 and the nature of binding between the molecules

The LPCTrap facility is coupled to the low-energy beam line LIRAT of the SPIRAL source at GANIL (France). The facility comprises an RFQ trap for beam preparation and a transparent Paul trap for in-trap decay studies. The system has been tested for several ion species. The Paul trap has been fully characterized for ⁶Li⁺ and ²³Na⁺ ions. This characterization together with GEANT4 simulations of the in-trap decay setup (Paul trap and detection system) has permitted to predict the effect of the size of the ion cloud on the decay study of ⁶He⁺.     

First Observation for Isotope 265Bh(Z=107)

New isotope ²⁶⁵Bh(Z=107) was produced in bombardment of an ²⁴³Am target with 135MeV ²⁶Mg ions at HIRFL. Identification was made by observation of correlated α particle decays between the new isotope ²⁶⁵Bh and its ²⁶¹Db and ²⁵⁷Lr daughters with four pairs of detectors. A total of 8 correlated decay events of ²⁶⁵Bh and 4 decay events of ²⁶⁴Bh were identified. ²⁶⁵Bh decays with a 0.94+0.70-0.31s half-life by emission of α particle with an average energy of (9.24±0.05)MeV.     

MR elastography of the head and neck: Driver design and initial results

Purpose

The purpose was to describe the design and fabrication of a driver suitable for magnetic resonance elastography (MRE) of the head and neck and to assess its performance in evaluating human parotid gland, lymph nodes and thyroid at 3.0 T.

Materials and methods

A head and neck driver was fabricated using a commercial transducer, headrest mould and piston extension. Driver performance was tested using a motion-sensitized spin-echo MRE pulse sequence. Six healthy volunteers and three patients (two metastatic nodes and one papillary carcinoma) were evaluated using MRE. Viscoelastic maps were computed to obtain storage modulus (G’) and loss modulus (G”) of the normal parotid and thyroid, metastatic node and thyroid cancer. Reproducibility was assessed by coefficient of variation.

Results

All subjects completed MRE examination without discomfort. Initial G’ and G” values were as follows: normal parotid gland, 1.12 kPa and 0.48 kPa; thyroid, 0.58 kPa and 0.42 kPa; metastatic node, 0.66 kPa and 0.58 kPa; and thyroid cancer, 0.17 kPa and 0.28 kPa. Based on parotid data, the coefficient of variation for G’ and G” was 4.7% and 9.8%.

Conclusion

A new MRE driver for head and neck was successfully implemented, and our initial results suggested the device was suitable for the mechanical assessment of tissues in the head and neck.     

New Low-spin Levels in 76Se and Discussion of Its Yrast Band Structure

The decay of bromine–76 was studied using compton–suppressed spectrometer and high–purity ge detectors in singles and coincidence mode, respectively. bromine–76 was produced via two reactions,i. e.,⁷⁵As(α,3n)⁷⁶Br and ⁷⁶Se(p, n)⁷⁶Br.the results of these experiments verified the previously reported levels and gammas of ⁷⁶Se. in addition to the previously described transitions and levels, 39 new γ–rays and 15 new energy levels were found for the first time. spins and parities for new levels are proposed based on the calculated logft values, de–excitation modes of the observed states, and some nuclear reaction experiment results. a new decay scheme of ⁷⁶Br is proposed in the present work. combining with the high–spin states observed by the in–beam γ–ray spectroscopy of a previous decay work, the positive–parity yrast states were compared with the results from calculations in the framework of the projected shell model.     

Background neutron in the endcap and barrel regions of resistive plate chamber for compact muon solenoid/large hadron collider using GEANT4

In this study the performance of double gap RPC has been tested by GEANT4 Monte Carlo simulation code. The detector response calculations taken as a function of the neutron energy in the range of 0.01 eV-1 GeV have been simulated through RPC set-up. In order to evaluate the response of detector in the LHC background environment, the neutron spectrum expected in the CMS muon endcap and barrel region were taken into account. A hit rate of about 165.5 Hz cm⁻², 34 Hz cm⁻², 33.6 Hz cm⁻², and 27.0 Hz cm⁻² due to an isotropic neutron source is calculated using GEANT4 standard electromagnetic package for a 20 × 20 cm² RPC in the ME1, ME2, ME3 and ME4, respectively. While for the same neutron source and using GEANT4 package a hit rate of about 0.42 Hz cm⁻², 0.7182 Hz cm⁻² was measured for the MB1 and MB4 stations respectively. Similar characteristics of hit rates have been observed for GEANT4 low electromagnetic package.      

Femtosecond Third-Order Optical Nonlinearity of Au：Bi203 Nanocomposite Films

Ultrafast third-order optical nonlinearities of the as-deposited and annealed Au：Bi2O3 nanocomposite films deposited by magnetron cosputtering are investigated by using femtosecond time-resolved optical Kerr effect （OKE） and pump probe techniques. The third-order optical nonlinear susceptibility is estimated to be 2.6Ф×10^- 10 esu and 1.8 × 10.9 esu at wavelength of 800nm, for the as-deposited and the annealed film, respectively. The OKE signal of the as-deposited film is nearly temporally symmetrical with a peak centred at zero delay time, which indicates the dominant contribution from intraband transition of conduction electrons. For the annealed film, the existence of a decay process in OKE signal implies the important contribution of hot electrons. These characteristics are in agreement with the hot electron dynamics observed in pump probe measurement.     

DECAY PROCESSES IN MASSIVE STRATON MODEL OF MESONS

Using the B-S wave functions of mesons in the massive straton model^[1], we discuss their weak decay, electromagnetic decay, and particularly hadronic decay processes. Not only f_π≈f_K, 1^－→l⁺l^－ rate are successfully explained, the predicted widths for various hadronic decays are also in good agreement with experimental data.