Alkaloids of Aconitum sajanense II. Structure of dehydroacosanine

The new alkaloid dehydroacosanine has been isolated from the roots ofAconitum sajanense Kumin, and its structure has been established by spectral and chemical methods.Institute of Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 531–534, September–October, 1992.     

Alkaloids of Aconitum sajanense II. Structure of dehydroacosanine

The new alkaloid dehydroacosanine has been isolated from the roots ofAconitum sajanense Kumin, and its structure has been established by spectral and chemical methods.     

Alkaloids of Aconitum kirinense. Structure of akirine

The known alkaloid lepenine and the new diterpene alkaloid akirine have been isolated from the epigeal part ofAconitum kirinense Nakai. To establish the structure of akirine, its spectral characteristics have been studied and an x-ray structural analysis has been made. It is 1α,8β-dihydroxy-16β-methoxy-9β,14β-methylenedioxy-3β,4β-epoxy-N-ethylaconitane — the first diterpene alkaloid with a lycoctonine skeleton containing a 9,14-methylenedioxy group and a β-oriented substituent at C14.     

Alkaloids of Aconitum kirinense. Structure of akirine

The known alkaloid lepenine and the new diterpene alkaloid akirine have been isolated from the epigeal part ofAconitum kirinense Nakai. To establish the structure of akirine, its spectral characteristics have been studied and an x-ray structural analysis has been made. It is 1,8-dihydroxy-16-methoxy-9,14-methylenedioxy-3,4-epoxy-N-ethylaconitane — the first diterpene alkaloid with a lycoctonine skeleton containing a 9,14-methylenedioxy group and a -oriented substituent at C14.Institute of Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 534–538, September–October, 1992.     

Alkaloids of Aconitum barbatum. Structure of bataconine

The epigeal part ofAconitum barbatum gathered in the early vegetation period in the environs of Ulan-Bator has yielded delcosine, lycoctonine, songorine, and the new base bataconine. The structure of bataconine has been shown on the basis of spectral characteristics (IR, NMR, and mass spectra) and also of a correlation with the known alkaloid neoline.Institute of the Chemistry of Plant Substances, Uzbek SSR Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 237–239, March–April, 1988.     

Alkaloids of Aconitum coreanum VI. Structure of acoridine

The new C₂₀-diterpene alkaloid acoridine has been isolated from the epigeal part ofAconitum coreanum (Levl.) Rapaics, and the structure of 14-hydroxy-2-propionylhetisine has been established for it on the basis of spectral characteristics. Acoridine is the first diterpene alkaloid esterified by propionic acid.Institute of Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 91–93, January–February, 1991.     

Alkaloids of Aconitum coreanum VIII. Structure of coryphidine

A new C₂₀-diterpene alkaloid of the coryphine type has been isolated from the plantAconitum coreanum (Levl.) Rapaics, and it has been called coryphidine. Its structure has been established on the basis of an analysis of IR and¹H and¹³C NMR spectra. This is the second diterpene alkaloid having a hexahydro-N-methylindole fragment at C-17. Coryphidine contains an imide grouping, which is unusual for a diterpene skeleton.Institute of Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 243–246, March–April, 1992.     

Alkaloids of Aconitum tuberosum. Structure of Tuberaconitine and Tubermesaconitine

Total alkaloids ofAconitum tuberosumroots afforded neoline and two new alkaloids, tuberaconitine and tubermesaconitine. The structures of the new alkaloids were proved based on spectral data and chemical transformations from aconitine and mesaconitine     

Alkaloids of the epigeal part of Aconitum talassicum. Structure of actaline

The epigeal part ofAconitum talassicum M. Pop. has yielded, in addition to five alkaloids known previously, kobusine, pseudokobusine, and the new alkaloid actaline. The structure of the latter has been established on the basis of an x-ray structural analysis. Actaline is the first C₂₀ diterpene alkaloid with a lycoctonine skeleton.Institute of the Chemistry of Plant Substances, Uzbek SSR Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, Vol. 1, pp. 39–44, January–February, 1989.     

Alkaloids of Aconitum rubricundum

The known alkaloids isolappaconitine (I), 9-deoxylappaconotine (II), lycaconitine (III), puberaconitine (IV), lycoctonine (V), ranaconitine (VI), ajacine (VII), and septentriodine (VII), and an unidentified alkaloid with mp 203–205°C have been isolated from the epigeal part of the Far-Eastern plantAconitum rubricundum. Institute of Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 403–407, May–June, 1991.     

Alkaloids of Aconitum talassicum

Three new C-20 diterpene alkaloids (talassamine (I), talassimidine (II), and talassimine (III)) and the known alkaloid lappaconitine have been isolated from the epigeal part ofAconitum talassicum (Ranunculaceae). The structures of the new alkaloids proposed on the basis of spectral characteristics and chemical transformations have been confirmed by an x-ray structural analysis of talassimine.Institute of Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 93–98, January–February, 1991.     

Alkaloids of Aconitum orientale

Institute of the Chemistry of Plant Substances, Uzbek Academy of Sciences, Tashkent. Pyatigorsk Pharmaceutical Institute. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 864–865, November–December, 1991.