一类具有脉冲免疫传染病模型SIVS的全局稳定性

讨论了一类具有脉冲免疫的媒介传播的SⅣS流行病模型.疾病的进程依赖感染年龄,时刻t传染率受时刻t-τ媒介种群的影响.模型存在一无病周期解.分析表明存在依赖于脉冲周期和脉冲免疫比例的基本再生数R_0(p,T),当R_0(p,T)<1时,无病周期解是全局稳定的.     

带有脉冲免疫和传染年龄的传染病模型的全局吸引性

讨论了带有脉冲免疫和传染年龄的传染病模型.传染类的恢复率是传染年龄的函数,当染病再生数小于1时,文章得到无病周期解是全局吸引的.如果总人口规模变化,也可得到类似的结论.最后,提出了带有脉冲免疫和传染年龄传染病模型待解决的问题.     

关于一个脉冲用药的HIV免疫模型的研究

对一个脉冲用药的HIV免疫模型进行研究,发现在用药间隔足够小时,预防抗化剂的脉冲使用通过使T细胞水平无限接近于未被感染的免疫水平来保持个体的免疫功能,并且文中进一步给出这个合适的用药间隔估计.这对指导AIDS治疗临床实践具有参考意义.     

一类具有垂直传染与脉冲免疫的SEIR传染病模型的全局分析

考虑了一个具有垂直传染与积分时滞的SEIR传染病动力学模型.分析了该模型在脉冲免疫接种条件下的动力学行为,获得了传染病灭绝的充分条件,进而运用脉冲时滞泛函微分方程理论,获得了含有时滞的系统持久性的充分条件,并且证明了积分时滞与脉冲免疫能对模型的动力学行为产生显著的影响.     

一类具有脉冲免疫治疗的HIV-1感染模型的动力学分析

该文基于一类HIV-1感染免疫治疗模型，研究了一类具有脉冲免疫治疗的HIV-1感染模型.借助脉冲微分方程理论，研究了脉冲免疫治疗模型解的非负性和一致有界性.利用Floquet乘子理论和微分方程的比较定理，推导出脉冲免疫模型无感染周期解局部和全局渐近稳定以及HIV-1一致持续的阈值条件.通过数值模拟，比较了3种不同治疗方案的治疗效果，验证了脉冲免疫治疗的有效性.数值模拟结果表明，当药物输入量足够大或服药间隔适当短时，从理论上可以有效控制甚至根除病毒.     

脉冲输入免疫因子的HBV模型的稳定性和持久性分析

提出了一个数学模型,用于研究脉冲投放免疫因子对HBV传染病动力学的影响.通过利用脉冲微分不等式和比较定理,证明了HBV模型的无病周期解的存在性,给出了无病周期解的全局渐近稳定性和系统的持续性的充分条件.研究结果表明:短的投放周期或适当的免疫因子投放量可以导致HBV的清除.     

脉冲输入免疫因子的HBV模型的稳定性和持久性分析

提出了一个数学模型,用于研究脉冲投放免疫因子对HBV传染病动力学的影响.通过利用脉冲微分不等式和比较定理,证明了HBV模型的无病周期解的存在性,给出了无病周期解的全局渐近稳定性和系统的持续性的充分条件.研究结果表明:短的投放周期或适当的免疫因子投放量可以导致HBV的清除.     

带有脉冲免疫和传染年龄的SIV传染病模型解的存在性

我们建立带有脉冲免疫和传染年龄的SIV传染病模型,这类传染病在潜伏期具有传染性,总人口规模依赖时间,并且传染类的康复率和传染年龄有关.我们证明此类模型解存在唯一.     

具有多时滞和垂直传染的脉冲接种流行病模型

在潜伏期和感染期是常数的情况下,给出了一个具有两个时滞和脉冲免疫的SEIR流行病模型.利用频闪映射的离散动力系统,得到了无病周期解的表达式以及全局吸引的条件是R*<1.此外,还证明了疾病一致持续的条件足R*>1.结论表明较短的脉冲接种间隔或较大的脉冲接种率将导致疾病的灭绝.结论还表明潜伏期和感染期是导致地方病的主要因素.     

脉冲接种作用下具有时滞的传染病模型分析

本文建立了一类具有潜伏期和免疫期的双时滞SEIRS传染病模型,在脉冲免疫接种和垂直传染条件下,分析了其全局动力学行为.利用频闪映射,获得了无病周期解,给出了此周期解的全局吸引性,并获得了系统一致持续生存的条件.     

Clustering Methods in Microarrays

Summary DCT Given a finite set of points in an Euclidean space the \emph{spanning tree} is a tree of minimal length having the given points as vertices. The length of the tree is the sum of the distances of all connected point pairs of the tree. The clustering tree with a given length of a given finite set of points is the spanning tree of an appropriately chosen other set of points approximating the given set of points with minimal sum of square distances among all spanning trees with the given length. DCM A matrix of real numbers is said to be column monotone orderable if there exists an ordering of columns of the matrix such that all rows of the matrix become monotone after ordering. The {\emph{monotone sum of squares of a matrix}} is the minimum of sum of squares of differences of the elements of the matrix and a column monotone orderable matrix where the minimum is taken on the set of all column monotone orderable matrices. Decomposition clusters of monotone orderings of a matrix is a clustering ofthe rows of the matrix into given number of clusters such that thesum of monotone sum of squares of the matrices formed by the rowsof the same cluster is minimal.DCP A matrix of real numbers is said to be column partitionable if there exists a partition of the columns such that the elements belonging to the same subset of the partition are equal in each row. Given a partition of the columns of a matrix the partition sum of squares of the matrix is the minimum of the sum of square of differences of the elements of the matrix and a column partitionable matrix where the minimum is taken on the set of all column partitionable matrices. Decomposition of the rows of a matrix into clusters of partitions is the minimization of the corresponding partition sum of squares given the number of clusters and the sizes of the subsets of the partitions.     

Noncommutative geometry and motives: The thermodynamics of endomotives

We combine aspects of the theory of motives in algebraic geometry with noncommutative geometry and the classification of factors to obtain a cohomological interpretation of the spectral realization of zeros of L-functions. The analogue in characteristic zero of the action of the Frobenius on ?-adic cohomology is the action of the scaling group on the cyclic homology of the cokernel (in a suitable category of motives) of a restriction map of noncommutative spaces. The latter is obtained through the thermodynamics of the quantum statistical system associated to an endomotive (a noncommutative generalization of Artin motives). Semigroups of endomorphisms of algebraic varieties give rise canonically to such endomotives, with an action of the absolute Galois group. The semigroup of endomorphisms of the multiplicative group yields the Bost-Connes system, from which one obtains, through the above procedure, the desired cohomological interpretation of the zeros of the Riemann zeta function. In the last section we also give a Lefschetz formula for the archimedean local L-factors of arithmetic varieties.     

Creep of polymer concrete in the nonlinear region

Two polyester-based polymer concretes with various volume content of diabase as an extender and aggregate are tested in creep under compression at different stress levels. The phenomenological and structural approaches are both used to analyze the experimental data. Common features of changes in the instantaneous and creep compliances are clarified, and a phenomenological creep model which accounts for the changes in the instantaneous compliance and in the retardation spectrum depending on the stress level is developed. It is shown that the model can be used to describe the experimental results of stress relaxation and creep under repeated loading. Modeling of the composite structure and subsequent solution of the optimization problem confirm the possibility of the existence of an interphase layer more compliant than the binder. A direct correlation between the interphase volume content and the instantaneous compliance of the composite is revealed. It is found that the distinction in nonlinearity of the viscoelastic behavior of the two polymer concretes under investigation can be due to the difference in their porosity. Submitted to the 11th International Conference on Mechanics of Composite Materials (Riga, June 11–15, 2000.) Translated from Mekhanika Kompozitnykh Materialov, Vol. 36, No. 2, pp. 147–164, 2000.     

Peridynamics via finite element analysis

Peridynamics is a recently developed theory of solid mechanics that replaces the partial differential equations of the classical continuum theory with integral equations. Since the integral equations remain valid in the presence of discontinuities such as cracks, the method has the potential to model fracture and damage with great generality and without the complications of mathematical singularities that plague conventional continuum approaches. Although a discretized form of the peridynamic integral equations has been implemented in a meshless code called EMU, the objective of the present paper is to describe how the peridynamic model can also be implemented in a conventional finite element analysis (FEA) code using truss elements. Since FEA is arguably the most widely used tool for structural analysis, this implementation may hasten the verification of peridynamics and significantly broaden the range of problems that the practicing analyst might attempt. Also, the present work demonstrates that different subregions of a model can be solved with either the classical partial differential equations or the peridynamic equations in the same calculation thus combining the efficiency of FEA with the generality of peridynamics. Several example problems show the equivalency of the FEA and the meshless peridynamic approach as well as demonstrate the utility and robustness of the method for problems involving fracture, damage and penetration.     

Analysis of the Stress State of the Surface Layer of a Polymeric Mass upon Filling of Bulky Compression Molds

The stress state of the surface layer of a polymeric mass during filling of bulky compression molds is analyzed. It is shown that, at particular rheological characteristics of the mass, temperature, and filling rates, cracking of the surface layer occurs, which leads to defects in the finished products. A physical analysis of this process makes it possible to conclude that the cracks arise due to the normal stresses operating in the front region of the moving polymeric mass. It is found that, under certain flow conditions, areas with a pressure lower than the atmospheric one appear on the surface of the polymer. If the tensile stresses arising in these local regions are higher than the tensile strength of the mass, the continuity of the composition is broken in the direction determined by the greatest rate of the normal deformation. To confirm the reliability of the crack-formation mechanism proposed, the distribution of the pressure and normal stresses over the free surface is calculated based on a numerical method. These calculations show that, by comparing the stress level achieved in the front region with the tensile-strength characteristics of the polymeric composition, it is possible to predict, with a sufficient accuracy, the possibility of crack formation in the surface layer of such a mass under given flow conditions and thus to solve the question on flawless manufacturing of products.     

基于综合重要度的动车组多部件系统机会维修策略研究

针对我国动车组列车现行维修方式,提出基于综合重要度序列的动车组多部件系统机会维修策略,对提高系统可靠度贡献大的关键部件进行准时优先维修。建立部件综合重要度指数计算模型,并依据其对部件维修优先级进行排序。以维修总成本最低为目标计算单部件最优维修周期及时刻,以系统维修总成本最低为目标,以关键部件的维修时刻为系统停机时刻建立考虑重要度的多部件系统机会维修模型。算例选取某型动车组四级修时更换的四部件系统为研究对象,讨论机会维修里程窗的大小及其偏移量对维修效果的影响,对比结果表明,考虑综合重要度的机会维修策略能够在维修费用基本持平的条件下,保证对系统可靠性贡献大的关键部件的可靠性,进而保证系统的整体可靠性。     

The Dirichlet divisor problem,traces and determinants for complex powers of the twisted bi-Laplacian

Estimating the counting function for the eigenvalues of the twisted bi-Laplacian leads to the Dirichlet divisor problem, which is then used to compute the trace of the heat semigroup and the Dixmier trace of the inverse of the twisted bi-Laplacian. The zeta function regularizations of the traces and determinants of complex powers of the twisted bi-Laplacian are computed. A formula for the zeta function regularizations of determinants of heat semigroups of complex powers of the twisted bi-Laplacian is given.     

城市老旧居住小区交通环境评价指标与评价方法

定量的评判城市老旧居住小区整体交通环境质量并进而科学有效的提出老旧小区交通环境更新与改善措施,对城市老旧居住小区交通环境进行了调查,明确了老旧居住小区存在的突出交通问题,并提出了城市老旧居住小区交通环境评价的指标体系,包括行人跨路出行指数、无人行道路段长度占比、停车泊位供需比、路内非法停车占比、平均停车步行距离、泊位数量户数比、人均步行空间、无障碍通道、盲道设置比例、非机动车泊位供需比、地面停放车辆数小区面积比、外部穿行交通周转量小区面积比等。并给出了具体指标的计算方法与获得办法。以长沙市四个典型老旧居住小区为例,对评价方法进行了论证,并得到城市老旧居住小区存在的一般问题,包括人车混杂、人车交织现象严重,停车泊位短缺、车辆乱停乱放,交通设施、特别是弱势群体交通设施缺乏。给出的评价指标、评价方法与结论可为城市老旧小区改造更新,特别是其中很重要的交通环境更新提供决策依据。     

Utilization and maintenance in a model with scrapping

We consider a productive asset, called equipment or capital good, and we examine the properties of, as well as the interactions between, the operating policies, which are determined by its optimal utilization and maintenance, and the capital policy of scrapping, which defines the optimal time when the productive asset is retired from its current use. Starting with an abstract model and using the approach of optimal control, initially we characterize the various types of equipment by assigning to them a single total profit index, which indicates how the above policies affect the flow of operating revenues plus capital gains or losses. This index is a function of market-determined prices. So using it we then investigate how the operating and capital policies are influenced by the rate of discount, the price of new equipment, and the rise or fall of the price of new equipment relative to the value of its output. Among other interesting results, we find that the effects of these prices on the nature and interactions of optimal policies depend crucially on whether the equipment is of the usual profit making type, where output is the main source of revenue, or of the antique type, where the main source of revenue is capital gains.     

Mario Pieri’s address at the University of Catania

The contributions made by the Italian mathematician Mario Pieri (1860-1913) are well known in the field of geometry. Pieri was a member of the School of Peano at the University of Turin. There he became engaged both by the problems of logic and by the philosophical aspects of Peano’s epistemology. This article was motivated by Pieri’s address given at the University of Catania, at the inauguration of the 1906-1907 academic year. My aim is to identify Pieri’s philosophical premises as found in his works and to present them in the general framework of the historical development of the Peano School.