Design of a surface plasmon resonance biosensor based on photonic crystal fiber with elliptical holes

In this paper, a photonic-crystal fiber based plasmonic biosensor in which gold is used as the plasmonic material is proposed. The introduced sensor is designed in such a way that the plasmonic metal layer and the sensing layer are placed outside the fiber structure so that the fabrication process and the numerical analysis has become comparatively much easier. The proposed plasmonic biosensor properties are calculated numerically using the finite element method. Amongst the parameters affecting the performance of the biosensor are the thickness of the gold layer and the diameter of the central cavity. By applying the wavelength interrogation method, the maximum sensitivity and the resolution of the proposed biosensor are computed as 5723.5 nm/RIU and 1.74?×?10^?5 RIU, respectively. The proposed structure with the above properties is suitable for detecting biological molecules, organic chemicals and analytes.     

Measurement of refractive index variation by differential surface plasmon resonance technique

A differential detection technique combined with a surface plasmon resonance technique is proposed for refractive index variation measurement. The experimental results demonstrate that our system can attain a resolution of 1.2 × 10^?5 RIU (refractive index unit). In addition, a method for two-dimensional detection of the refractive index variation is demonstrated. The system is free from the influence of optical source fluctuation, and can improve the measurement sensitivity.     

Measurement of Ar(I) and Ar(II) transition probabilities in LTE ARC plasmas

The transition probabilities of two Ar(I) lines and one Ar(II) line have been measured in emission on wall-stabilized argon arc plasmas (0·5×10⁵?p, Nm^-2?3×10⁵; 10,000?T, K?20,000; 10²²?N_e, m^-3?5×10²³) using the “method of best fit (MBF)”. The results (without line-wing correction) are for Ar(I) at 714·7 nm, A_nm=5·66×10⁵ s^-1±5%; for Ar(I) at 430·0 nm, A_nm=3·40×10⁵ s^-1±5%; for Ar(II) at 480·6 nm, A_nm=8·82×10⁷ s^-1±7%. These values were not influenced by deviations from LTE, which have been observed at electron number densities n_e?10²³ m^-3. The small uncertainties were achieved after careful corrections of different sources of error.     

Integrated photonic glucose biosensor using a vertically coupled microring resonator in polymers

A photonic glucose biosensor incorporating a vertically coupled polymeric microring resonator was proposed and accomplished. The concentration of a glucose solution was estimated by observing the shift in the resonant wavelength of the resonator. For achieving higher sensitivity the contrast between the effective refractive index of the polymeric waveguide and that of the analyte was minimized. Actually, the effective refractive index of the polymeric waveguide (n = ∼1.390) was substantially close to that (n = ∼1.333) of the fresh solution with no glucose. The fabricated resonator sensor with the free spectral range of 0.66 nm yielded a sensitivity of ∼280 pm/(g/dL), which corresponds to ∼200 nm/RIU (refractive index units) as a refractometric sensor, and provided a detection limit of refractive index change on the order of 10⁻⁵ RIU.     

Highly Selective and Stable Florescent Sensor for Cd(II) Based on Poly(azomethine-urethane)

In this study a kind of poly(azomethine-urethane); (E)-4-((2 hydroxyphenylimino) methyl)-2-methoxyphenyl 6-acetamidohexylcarbamate (HDI-co-3-DHB-2-AP) was prepared as in the literature and employed as a new fluorescent probe for detection of Cd(II) concentration. The photoluminescence (PL) measurements were carried out in the presence of several kinds of heavy metals. HDI-co-3-DHB-2-AP gave a linearly and highly stable response against Cd(II) as decreasing a new emission peak at 562 nm. Possible interferences of other ions were found too low. Detection limit of the sensor was found as 8.86?×?10^?4?mol?L^?1. Resultantly, HDI-co-3- DHB-2-AP could be effectively used as an optical Cd(II) sensor.     

Investigation on micro/nanofiber Bragg grating for refractive index sensing

We propose a refractometric sensor based on micro/nanofiber Bragg grating (MNFBG). The refractive index (RI) sensing performance dependence on the fiber radius and Bragg grating period of the sensor, as well as the temperature cross-sensitive effect, is investigated theoretically. The simulation results demonstrate that 400 nm-radius MNFBG has a linear response to RI ranging from 1.3 to 1.39 with a sensitivity as high as 992.7 nm/RIU and half temperature cross-sensitivity of normal FBG. A maximum sensitivity of up to 1200 nm/RIU and an outstanding RI resolution of 8.3 × 10^-6 can be achieved. MNFBG has high potential in various types of optical fiber sensor applications.     

Absorption enhancement and sensing properties of Ag diamond nanoantenna arrays

Noble metal nanoantenna could effectively enhance light absorption and increase detection sensitivity. In this paper,we propose a periodic Ag diamond nanoantenna array to increase the absorption of thin-film solar cells and to improve the detection sensitivity via localized surface plasmon resonance. The effect of nanoantenna arrays on the absorption enhancement is theoretically investigated using the finite difference time domain(FDTD) method with manipulating the spectral response by geometrical parameters of nanoantennas. A maximum absorption enhancement factor of 1.51 has been achieved in this study. In addition, the relation between resonant wavelength(intensity reflectivity) and refractive index is discussed in detail. When detecting the environmental index using resonant wavelengths, a maximum detection sensitivity of about 837 nm/RIU(refractive index unit) and a resolution of about 10-3RIU can be achieved. Moreover, when using the reflectivity, the sensitivity can be as high as 0.93 AU/RIU. Furthermore, we also have theoretically studied the effectiveness of nanoantennas in distinguishing chemical reagents, solution concentrations, and solution allocation ratios by detecting refractive index. From the results presented in this paper, we conclude that this work might be useful for biosensor detection and other types of detections.     

Poly(1-amino-5-chloroanthraquinone): Highly Selective and Ultrasensitive Fluorescent Chemosensor For Ferric Ion

Poly(1-amino-5-chloroanthraquinone) (PACA) was firstly synthesized by a chemically oxidative interfacial polymerization. The PACA has been developed as a fluorescent sensor for the determination of Fe(III) in semi-aqueous solution at pH 7.0. The sensor exhibited remarkably high sensitivity toward Fe³⁺ since the fluorescence of the polymer could be significantly quenched even though trace Fe³⁺ was added. The sensor showed a linear fluorescence emission response over a wide concentration range from 1.0?×?10^?10 to 1.0?×?10^?4 M, with an ultra-low detection limit of 2.0?×?10^?11 M. The quenching of the fluorescence was found to be static one due to the formation of non-fluorescent complex in the ground state.     

Refractive index sensors based on Ag-metalized nanolayer in microstructured optical fibers

We propose refractive index sensors based on Ag-metalized nanolayer in microstructured optical fibers. The surface plasmon resonance modes and the sensing properties are theoretically analyzed using finite element method (FEM). In the calculation, Drude–Lorentz model is used to describe the Metal Dielectric constant. The calculation results show that the sensitivity of Ag-metalized SPR sensor can reach 1500 nm/RIU corresponding to a resolution of 6.67 × 10^?5 RIU. Comparing with conventional detecting material-Au under the same structure, the sensitivity and 3 dB bandwidth of our device are better.     

Highly sensitive electrochemical detection of dopamine and uric acid on a novel carbon nanotube-modified ionic liquid-nanozeolite paste electrode

A novel biosensor has been constructed by incorporating modified nanosized natural zeolite and 3-hydroxypropanaminium acetate (HPAA) as a novel room temperature ionic liquid, supported on multiwalled carbon nanotube (MWCNTs) and employed for the simultaneous determination of dopamine (DA) and uric acid (UA). A detailed investigation by transmission electron microscopy and electrochemistry is performed in order to elucidate the preparation process and properties of the composites. The voltammetric studies using the modified carbon paste electrode show two well-resolved anodic peaks for DA and UA with a potential difference of 160 mV, revealing the possibility of the simultaneous electrochemical detection of these compounds. The modified carbon paste electrode shows good conductivity, stability, and extraction effect due to the synergic action of HPAA, MWCNTs, and iron ion-doped natrolite zeolite. Under optimized conditions, the peak currents are linear from 8.12?×?10^?7 to 3.01?×?10^?4?mol?L^?1 and from 9.31?×?10^?7 to 3.36?×?10^?4?mol?L^?1 with detection limits of 1.16?×?10^?7 and 1.33?×?10^?7?mol?L^?1 for DA and UA using the differential pulse voltammetric method, respectively. Finally, the modified carbon paste electrode proved to have good sensitivity and stability and is successfully applied for the simultaneous determination of DA and UA in human blood serum and urine samples.     

Numerical study of a highly sensitive surface plasmon resonance sensor based on circular-lattice holey fiber

A new design of surface plasmon resonance (SPR) sensor employing circular-lattice holey fiber to achieve high-sensitivity detection is proposed. The sensing performance of the proposed sensor is numerically investigated and the results indicate that our proposed SPR sensor can be applied to the near-mid infrared detection. Moreover, the maximum wavelength sensitivity of our proposed sensor can reach as high as 1.76×10⁴ nm/refractive index unit (RIU) and the maximum wavelength interrogation resolution can be up to 5.68×10^-6 RIU when the refractive index (RI) of analyte lies in (1.31, 1.36). Thanks to its excellent sensing performance, our proposed SPR sensor will have great potential applications for biological analytes detection, food safety control, bio-molecules detection and so on.     

Rapid Fluorescent Detection of Escherichia coli K88 Based on DNA Aptamer Library as Direct and Specific Reporter Combined With Immuno-Magnetic Separation

Nucleic acid aptamers have long demonstrated the capacity to bind cells with high affinity so that they have been utilized to diagnose various important pathogens. In this study, a DNA aptamer library was on initial efforts developed to act as a specific reporter for rapid detection of enter toxigenic Escherichia coli (ETEC) K88 combined with immuno-magnetic separation (IMS). During a Whole-cell Systematic Evolution of Ligands by Exponential Enrichment (CELL-SELEX) procedure, the last selection pool against ETEC K88, which is named “DNA aptamer library” here, was selected and subsequently identified by flow cytometric analysis and confocal imaging. A K88 monoclonal antibody (mAb) with high affinity (K_aff: 1.616?±?0.033?×?10⁸ M^?1) against K88 fimbrial protein was prepared, biotinylated and conjugated to streptavidin-coated magnetic beads (MBs). After the bacteria were effectively captured and enriched from the complex sample by immuno-magnetic beads (IMBs), 5′-FITC modified aptamer library was directly bound to target cells as a specific reporter for its detection. The detection system showed clearly high specificity and sensitivity with the detection limit of 1.1?×?10³ CFU/ml in pure culture and 2.2?×?10³ CFU/g in artificially contaminated fecal sample. The results also indicated that fluorophore-lablled DNA aptamer library as specific reporter could generate more reliable signals than individual aptamer with best affinity against target cells and implied it would have great applied potential in directly reporting bacteria from complex samples combined with IMS technology.     

Negative curvature dependent plasmonic coupling and local field enhancement of crescent silver nanostructure

In this contribution, novel luminescent gold nanoclusters were synthesized by utilizing bovine serum albumin as templates with a simple, rapid, and one-pot procedure. The as-prepared gold nanoclusters were highly dispersed in aqueous solution and emitted an intense red fluorescence under UV light (365?nm). They exhibited strong fluorescence and the maximum excitation and emission wavelengths were 480 and 613.5?nm. In addition, the bovine serum albumin-stabilized gold nanoclusters were successfully utilized as novel fluorescent probes for the detection of quercetin for the first time. It was found that the addition of quercetin induced the strong fluorescence intensity of the gold nanoclusters to decrease. The decrease in fluorescence intensity of the gold nanoclusters caused by quercetin allowed the sensitive detection of quercetin in the range of 8.9?×?10^?8?C1.8?×?10^?4?mol?L^?1. The detection limit for quercetin is 1.8?×?10^?8?mol?L^?1 at a signal-to-noise ratio of 3. The present sensor for quercetin detection possessed a low detection limit and wide linear range. In addition, the real samples were analyzed with satisfactory results.     

Spectroscopy of YAl3(BO3)4:Cr3+ crystals following first principles and crystal field calculations

The CASTEP module of the Materials Studio package was used for calculations of the structural, electronic and optical properties of pure and Cr³⁺-doped YAl₃(BO₃)₄ (YAB). The exchange-correlation effects were treated within the generalized gradient approximation with the Perdew–Burke–Ernzerhof functional. The Monkhorst–Pack scheme k-points grid sampling was set at 3?×?3?×?4 for the Brillouin zone. The plane-wave basis set energy cutoff was set at 340?eV; ultrasoft pseudopotentials were used for all chemical elements. The convergence parameters were as follows: total energy tolerance 1?×?10^?5?eV/atom, maximum force tolerance 0.03?eV/nm, maximal stress component 0.05?GPa and maximal displacement 0.001?Å. The principal absorption peaks of the studied crystal were identified. The influence of 532?nm?cw, 300?mW laser radiation on the observed absorptions was studied.     

The Pt(110) phase transitions: A study by rutherford backscattering,nuclear microanalysis,LEED and thermal desorption spectroscopy

The adsorbate induced (1×2) (1×1) (2×1)p1g1 phase transitions on Pt(110) have been studied by Rutherford backscattering (RBS), nuclear microanalysis (NMA), LEED and thermal desorption spectroscopy. RBS data indicate that any displacement of the surface atoms from their expected bulk-like lattice sites in the (1×2) phase is ? 0.002 nm laterally and ? 0.007 nm vertically. This contraint eliminates models for the reconstruction which involve significant lateral displacements (e.g., the paired-atom or hexagonal overlayer models). The RBS data are consistent with both the rumpled model with up/down displacements not exceeding ~0.007 nm and the missing row model with an unrelaxed surface in which the out-of-plane vibrational amplitude is slightly enhanced. A c(8×4) phase, produced by CO (or NO) exposure at T?250 K, has also been characterized by RBS which demonstrated that 0.92×10¹⁵ Pt cm^?2 move on average by ~0.017 nm laterally out-of-registry with the bulk upon formation of this phase. The values of the saturation adsorbate coverages at T?200K were determined by NMA to be 0.92 ± 0.05×10¹⁵, 1.0 ± 0.06×10¹⁵ and 1.07 ± 0.10×10¹⁵ CO molecules, NO molecules and D atoms, respectively, per cm². The value of the saturation coverage by CO (θ = 1.0) supports recent models of the (2×1)p1g1 overlayer. The isosteric heat of adsorption of CO is 160 ± 15 kJ mol^?1 in the range 0.2?θ?0.5.     

Simultaneous Measurement of Refractive Index and Temperature Using a Hybrid Fiber Bragg Grating/Long-Period Fiber Grating Configuration

Abstract

A fiber optic sensing system for simultaneous measurement of refractive index and temperature, based on a hybrid fiber Bragg grating/long-period grating arrangement is described. The experimental results show that this setup has a good performance in terms of linearity and sensitivity, the ratiometric output changes 4%/0.001 RIU and 3.6%/°C, respectively. The sensor resolution for the refractive index is ≈2 × 10^?5 RIU. The simultaneous measurement of the refractive index and temperature was demonstrated. The sensing configuration has the ability to be read-out in reflection and works in the telecommunications window.     

Selective Fluorescence Sensing of Deoxycytidine 5��-Monophosphate (dCMP) Employing a Bis(diphenylphosphate)diimine Ligand

A new bis(diphenylphosphate)diimine ligand (BP1) was prepared and evaluated for its ability for selective detection of deoxycytidine 5??-monophosphate (dCMP). BP1 exhibited off-type fluorescence in the presence of dCMP. The fluorescence of BP1 was significantly quenched upon the addition of 2.5?×?10^?4 M dCMP and the detection limit was 1.25?×?10^?5 M in MeCN-H₂O (1:1, v/v). The binding ratio between BP1 and dCMP was determined to be 1:1 with the binding constant of 3.98?±?0.60?×?10^?3 M^?1.     

Leed,aes and photoemission measurements of epitaxially grown GaAs(001), (111)A and (1̄1̄1̄)B surfaces and their behaviour upon cs adsorption

Epitaxially grown GaAs(001), (111) and (1?1?1?) surfaces and their behaviour on Cs adsorption are studied by LEED, AES and photoemission. Upon heat treatment the clean GaAs(001) surface shows all the structures of the As-stabilized to the Ga-stabilized surface. By careful annealing it is also possible to obtain the As-stabilized surface from the Ga-stabilized surface, which must be due to the diffusion of As from the bulk to the surface. The As-stabilized surface can be recovered from the Ga-stabilized surface by treating the surface at 400°C in an AsH₃ atmosphere. The Cs coverage of all these surfaces is linear with the dosage and shows a sharp breakpoint at 5.3 × 10¹⁴ atoms cm^?2. The photoemission reaches a maximum precisely at the dosage of this break point for the GaAs(001) and GaAs(1?1?1?) surface, whereas for the GaAs(111) surface the maximum in the photoemission is reached at a higher dosage of 6.5 × 10¹⁴ atoms cm^?2. The maximum photoemission from all surfaces is in the order of 50μA Im^?1 for white light (T = 2850 K). LEED measurements show that Cs adsorbs as an amorphous layer on these surfaces at room temperature. Heat treatment of the Cs-activated GaAs (001) surface shows a stability region of 4.7 × 10¹⁴ atoms cm^?2 at 260dgC and one of 2.7 × 10¹⁴ atoms cm^?2 at 340°C without any ordering of the Cs atoms. Heat treatment of the Cs-activated GaAs(111) crystal shows a gradual desorption of Cs up to a coverage of 1 × 10¹⁴ atoms cm^?2, which is stable at 360°C and where LEED shows the formation of the GaAs(111) (√7 × √7)Cs structure. Heat treatment of the Cs-activated GaAs(1?1?1?) crystal shows a stability region at 260°C with a coverage of 3.8 × 10¹⁴ atoms cm^?2 with ordering of the Cs atoms in a GaAs(1?1?1?) (4 × 4)Cs structure and at 340°C a further stability region with a coverage of 1 × 10¹⁴ at cm^?2 with the formation of a GaAs(1?1?1?) (√21 × √21)Cs structure. Possible models of the GaAs(1?1?1?) (4 × 4)Cs, GaAs(1?1?1?)(√21 × √21)Cs and GaAs(111) (√7 × √7)Cs structures are given.     

New bis[N-(4-pyridyl)-P-Toluene Sulfonamide] Palladium Dichloride a Novel Fluorophore for Determination of Lysine Amino Acid

Here, we are describing the study of the chemiluminescence arising from the reaction of bis (2,4,6-trichlorophenyl) oxalate (TCPO) system with new bis [N-(4-pyridyl)-p-toluene sulfonamide] palladium dichloride (BSPC) as a novel luminescent. The optimum concentrations of all reagents such as sodium salicylate (SS) as catalyst, hydrogen peroxide as oxidizing reagent and the relationships between the chemiluminescence intensity and concentrations of TCPO, SS, hydrogen peroxide and BSPC are reported. After optimization the required reagents, the system were used for determination of amino acid lysine, as an effective and selective quencher in the solution functioning in a Stern–Volmer fashion. This resulted in the development of a facile and highly sensitive chemiluminescence detection scheme for the determination of lysine in biological samples. Ultimately, estimating quenching constant K _q of 4.29?×?10³ M^?1 was successfully carried out. Under the optimal conditions, the evaluated lower and upper detection limits of measurable concentration of lysine are 1.17?×?10^?7 and 3.18?×?10^?4 M, respectively.     

Analysis of the ν6(A″2) band of cyclopropane-d6 recorded under high resolution

The parallel band ν₆(A″₂) of C₃D₆ near 2336 cm^?1 has been studied with high resolution (Δν = 0.020 – 0.024 cm^?1) in the infrared. The band has been analyzed using standard techniques and the following parameters have been determined: B″ = 0.461388(20) cm^?1, D″_J = 3.83(17) × 10^?7 cm^?1, ν₀ = 2336.764(2) cm^?1, α^B = (B″ ? B′) = 8.823(12) × 10^?4 cm^?1, β^J = (D″_J ? D′_J) = 0, and α^C = (C″ ? C′) = 4.5(5) × 10^?4 cm^?1.