Synthesis and Chemical Behavior of the N-Morpholino- O-Alkyl-3-Methyl-1,2-Butadienephosphonic Acid Esters

Abstract

The synthesis and the reactivity of the titled compounds towards electrophilic and nucleophilic reagents have been discussed.     

Die Mikroidentifizierung von Alkylhalogeniden, O-Alkyl- und N-Alkylgruppen

Ohne Zusammenfassung     

Zur Mikroidentifizierung der niederen aliphatischen Alkohole, der O-Alkyl- und N-Alkylgruppen

Ohne Zusammenfassung     

3-(3＇-乙酰基-5＇-芳基-1＇,3＇,4＇-二氢噁二唑-2＇-)色酮的微波促进合成

将微波应用于促进有机合成是近年来兴起的新技术,已受到极大注意,我们采用简单的微波反应装置,成功地合成了3－杂环基取代的色酮,杂环基取代的色酮因其显著的生理活性,而成为近年来的研究特点,以3－甲酰基色酮为原料,与芳酰肼反应得到相应的芳酰腙,再用乙酸酐关环,合成了一系列3位为1,3,4－二氢恶二唑基取代的色酮（3）,为在合适的母体上引入杂环提供了一系新思路,合成路线如下。     

Synthesis of 3-Bromo-3-nitroacrylates

Russian Journal of Organic Chemistry -     

Synthesis of 3-functionalized 3-methylazetidines

1-t-Butyl- and 1-(4-methylbenzyl)-3-bromo-3-methylazetidines were prepared from the corresponding N-(2,3-dibromo-2-methylpropylidene)alkylamines and their propensity to undergo nucleophilic substitution at the 3-position by different nucleophiles was assessed, providing a convenient access to novel 3-alkoxy-, 3-aryloxy-, 3-hydroxy-, 3-cyano-, 3-carboxy-, 3-(aminomethyl)- and 3-(hydroxymethyl)azetidines.     

Synthesis of 3-methylcholanthrene

A novel synthesis of 3-methylcholanthrene is described which is operationally sipmler than the method in current use and is potentially applicable to the synthesis ofa wide range of other polycyclic hydrocarbons and their cracinogenic metabolites.     

Synthesis of 3-Triazenopyrroles

The 3-triazenopyrroles, a new class of pyrrole derivatives, were synthesized in quantitative yield by coupling 3-diazopyrroles with secondary amines.     

3-硝基邻苯二甲腈的合成

以邻苯二甲酸酐为原料,经过硝化、脱水、亚胺化、氨解、脱水5步反应,高产率地合成了3-硝基邻苯二甲腈,研究了邻苯二甲酸酐的硝化反应、3-硝基邻苯二甲酰胺的脱水条件对产率的影响。目标化合物的结构用元素分析,IR和^1H NMR表征。     

Synthesis of 3-arylaminoindazoles

3-Chloro(bromo)indazoles do not react with aromatic amines even under severe conditions. It was found that the hydrochlorides (hydrobromides) of aromatic amines catalyze the exchange of a halogen atom by an arylamino group.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 249–251, February, 1973.     

Synthesis of 3-fluoroazetidines

N-(Alkylidene or 1-arylmethylidene)-2-propenylamines were regiospecifically functionalized to novel N-(alkylidene or 1-arylmethylidene)-3-bromo-2-fluoropropylamines, which were proven to be excellent precursors for 3-fluoroazetidines.     

Synthesis of 3-phenoxyphenylacetonitrile

Russian Journal of General Chemistry -