Palladium-Catalyzed Coupling of Organo-Stannanes with Hypervalent Iodonium Salts

The palladium-catalyzed cross-coupling of organostannanes with iodonium salts in the presence of PdCl₂(0.5 mol %) or Pd/C(2 mol %) as Pd(O) source was accomplished at room temperature under aqueous conditions.     

有机高价碘盐参与的炔丙醇的交叉偶联反应

有机高价碘在钯（Ⅱ）／铜（Ⅰ）共催化作用下与炔丙醇发生交叉偶联反应生成3－取代炔丙醇。该反应不仅条件温和，产率很高，而且具有良好的区域选择性。所得产物均经熔点，IR及^1H NMR验证。     

Rapid Microwave-promoted Base-free Suzuki Coupling Reaction of Sodium Tetraphenylborate with Hypervalent Iodonium Salts in Water

The palladium chloride-catalyzed Suzuki coupling reaction of sodium tetraphenylborate with hypervalent iodonium salts was achieved under microwave irradiation in water without base in excellent yield. A convenient and rapid method for formation of carbon-carbon bonds was afforded.     

Hypervalent Iodine in Synthesis XXXIV: Palladium-Catalyzed Coupling Reaction of o-Hydroxyarylaldehydes with Hypervalent Iodonium Salts Via Cleavage of the Aldehyde C-H Bond

A novel way of preparation for o-hydroxyarylketones with mild conditions and good yields by palladium-catalyzed coupling reaction of o-hydroxyarylaldehydes with hypervalent iodonium salts via the cleavage of the aldehyde C-H bond has been reported.     

Palladium-Catalyzed Cross-Coupling of Organolead Compounds with Hypervalent Iodonium Salts

The palladium-catalyzed cross-coupling of hypervalent iodonium salts with organolead triacetates was achieved with Pd₂(dba)₃·CHCl₃ (5 mol %) in the presence of NaOMe (2 equiv) in CHCl₃ at room temperature.     

Palladium-Catalyzed Arylation and Vinylation of 2,3-Dihydrofuran with Hypervalent Iodonium Salts

The palladium-catalyzed arylation and vinylation of 2,3-dihydrofuran with aryl and alkenyl iodonium salts afforded 2-phenyl- or 2-alkenyl-2,5-dihydrofurans at room temperature in an aqueous medium.     

Palladium-Catalyzed Carbonylative Cross-Coupling of Organoboranes with Hypervalent Iodonium Salts: Synthesis of Aromatic Ketones

The cross-coupling reaction of organoboronic acids and carbon monoxide (1 atm) with aryl-, alkenyl-, and alkynyliodonium salts at room temperature afforded unsymmetric aromatic ketones in moderate yields.     

Hypervalent Iodine in Synthesis 44: Stereoselective Synthesis of Vinylic Selenides by the Reaction of Sodium Selenolates with Vinyl (Phenyl) Iodonium Salts

Vinylic selenides have been prepared stereoselectively by the reaction of sodium selenolates with vinyl(phenyl)iodonium salts with retention or inversion of the configurations.     

羰基化合物还原偶联为频呐醇反应的研究新进展

综述了近几年来羰基化合物还原偶联为频呐醇反应的研究新进展．     

钯和四齿膦配体催化剂应用于Heck反应的研究

设计合成了以联萘二胺为骨架的四齿膦配体N,N,N',N'-四(二苯基膦甲基)-(1,1'-联萘)-2,2'-二胺,并将其与钯组成的催化体系用于苯乙烯和芳卤的Heck反应,该催化体系对各种卤代芳烃都表现出了很高的催化活性.对活化底物对溴苯腈,即使底物与催化剂的物质的量比达到10 000,反应20 h几乎能达到定量转化;该催化体系对活性更低的杂环底物也取得了良好的催化效果.     

Alkenylation of C(sp3)−H Bonds by Zincation/Copper‐Catalyzed Cross‐Coupling with Iodonium Salts

α‐Vinylation of phosphonates, phosphine oxides, sulfones, sulfonamides, and sulfoxides has been achieved by selective C?H zincation and copper‐catalyzed C(sp³)?C(sp²) cross‐coupling reaction using vinylphenyliodonium salts. The vinylation transformation proceeds in high efficiency and stereospecificity under mild reaction conditions. This zincative cross‐coupling reaction represents a general alkenylation strategy, which is also applicable for α‐alkenylation of esters, amides, and nitriles in the synthesis of β,γ‐unsaturated carbonyl compounds.     

氨基酸盐酸盐催化二氧化碳与环氧化物的环化反应

利用氨基酸盐酸盐作为催化剂,二氧化碳可以和环氧化物发生偶联反应,高产率和高选择性地生成环状碳酸酯,详细研究了反应条件如二氧化碳压力,反应温度,时间及催化剂用量对反应的影响。     

Stereoselective Direct N-Trifluoropropenylation of Heterocycles with a Hypervalent Iodonium Reagent

The availability and synthesis of fluorinated enamine derivatives such as N-(3,3,3-trifluoropropenyl)heterocycles are challenging, especially through direct functionalization of the heterocyclic scaffold. Herein, a stereoselective N-trifluoropropenylation method based on the use of a bench-stable trifluoropropenyl iodonium salt is described. This reagent enables the straightforward trifluoropropenylation of various N-heterocycles under mild reaction conditions, providing trifluoromethyl enamine type moieties with high stereoselectivity and efficiency.     

水相中Pd/C催化的杂环芳卤的还原偶联反应研究

在H₂O-alcohol体系中通过Pd/C催化的还原偶联反应由杂环芳卤高收率的得到了二芳基化合物. 该方法操作简单, 环境友好, Pd/C可重复使用, 无需相转移催化剂也能得到较高收率. 讨论了醇、碱的种类和用量以及不同底物对反应收率的影响.     

Reductive Coupling of Aldimines Mediated with Samarium Catalyzed by Cp2TiCl2

Reductive coupling of aldimines into vicinal diamines mediated with samarium catalyzed by Cp₂TiCl₂ proceeds in refluxing THF with good yields.     

TiCl4/Al体系中低价钛诱导下的硝基苯还原偶联反应实验

设计了以铝粉为还原剂还原TiCl4形成TiCl4／Al的新体系，并成功地用于硝基苯的还原偶联反应，具有还原剂易得、条件温和、选择性好、收率较高等优点。这一实验涉及到有机化学的一个基本反应——还原偶联反应，在不同条件下经还原得到多种产物，并可实施产物间相互转化。合成也涉及到多种基本实验操作，并可根据实验结果及分析数椐推测反应过程。     

One-Pot Synthesis and Applications of N-Heteroaryl Iodonium Salts

An efficient one-pot synthesis of N-heteroaryl iodonium triflates from the corresponding N-heteroaryl iodide and arene has been developed. The reaction conditions resemble our previous one-pot syntheses, with suitable modifications to allow N-heteroaryl groups. The reaction time is only 30 min, and no anion exchange is required. The obtained iodonium salts were isolated in a protonated form, these salts can either be employed directly in applications or be deprotonated prior to use. The aryl groups were chosen to induce chemoselective transfer of the heteroaryl moiety to various nucleophiles. The reactivity and chemoselectivity of these iodonium salts were demonstrated by selectively introducing a pyridyl moiety onto both oxygen and carbon nucleophiles in good yields.     

碘(钅翁)盐在有机合成中的应用

本文就三价有机碘鎓盐,包括二芳基、芳基全氟烷基、芳基烯基、芳基炔基和芳基烯丙基碘鎓盐以及碘叶立德在有机合成上有用的反应进行综述。这些反应包括C-,O-,N-和S-基化,全氟烷基、烯基、炔基、烯丙基和亚烷基转移反应等。