Synthesis, Characterization and Biological Activity of Diorganotin（IV） Complexes of N-（3,5-Dibromosalicylidene）-α-amino Acid

The diorganotin（Ⅳ） complexes of N-（3,5-dibromosalicylidene）-α-amino acid, R2Sn（2-O-3,5-Br2C6H2CH= NCHRCOO）（where R=H, Me, i-Pr, Bz; R＇=n-Bu, Cy）, were synthesized by the reactions of diorganotin dichlorides with in situ formed potassium salt of N-（3,5-dibromosalicylidene）-α-amino acid and characterized by elemental analysis, IR and NMR （^1H, ^13C and ^119Sn） spectra. The crystal structures of n-Bu2Sn（2-O-3,5-Br2C6H2CH= NCHRCOO）（R=i-Pr, Bz） and Cy2Sn（2-O-3,5-Br2C6H2CH=NCHRCOO）（R=Me, Bz） were determined by X-ray single crystal diffraction and showed that the tin atoms are in a distorted trigonal bipyramidal geometry to form five- and six-membered chelate rings with the tridentate ligand. Bioassay results indicated that the compounds possess better in vitro antitumour activity against three human tumour cell lines, HeLa, CoLo205 and MCF-7, than cis-platin and moderate anti-bacterial activity against two bacteria, E. coli and S. aureus.     

Synthesis, Characterization and Crystal Structure of the First Tri-nuclear MFe2（M = Cu and Ni） Complexes Based on Nitroprusside

IntroductionSince 184 8,whenPlayfairpublishedthefirstpaperrelatedtonitroprussides ,1thetransitionmetalpenta cyanonitrosylmetallatehydrateshavebeenwidelystudiedbecauseoftheirimportantrolesinmolecularsieves ,cationexchangers,electronscavengersandradionuclidesor bents .2 4 Thenitroprussides ,regardlessofthecationicmetal,arecurrentlyemployedasreversibleinhibitorsofagroupofenzymesknownassuperoxidedismutases .5Recently ,using [Fe(CN ) 5(NO) ]2 - asabuildingblock ,somenitroprusside bridgedpolymeri…     

Synthesis,Crystal Structures and Properties of Two Novel Co（Ⅱ） and Cd（Ⅱ） Complexes of N-AcetyI-L-glutamic Acid and Imidazole Ligands

Two novel complexes {[Co（A-glu）（Im）2]·0.5H2O}n （1） and [Cd（A-glu）（Im）3]n （2） （H2A-glu=N-acetyl-L-glutamic acid, Im=imidazole） have been synthesized from the reaction of H2A-glu with Co（CH3COO）2·4H2O or Cd（CH3COO）2·2H2O in the presence of Im. Both of the complexes display different coordination environment and similar one-dimensional chain structure. The magnetic susceptibility measurements for 1 show a weak antiferromagnetic interaction between two cobalt（Ⅱ） ions bridged by A-glu ligand. The complex 2 exhibits an intense fluorescent emission in solid state at room temperature.     

Synthesis and Characterization of Chiral Organogallium and Indium Complexes with Salen Ligands

Several new chiral organogallium and indium complexes with chiral Salen(1 and 2) as anxciliary ligands have been synthesized and characterized by elemental analysis,IR,^1H NMR and Mass spectroscopy.For the gallium,Mono and bimetallic complexes were obtained,whereas ring closure complexes of indium were obtained.     

Synthesis, Characterization, Crystal Structure and Stability of a Ternary Cu（Ⅱ） complex with 1, 10-Phenanthroline and L-Valinate

It is important to research the mixed-ligand copper complexes containing bioligands, such as amino acids, nucleic acids and proteins, in exploring the functional mechanism of microelement copper in organism because the reaction of any micronutrient with two or more bioligands in the concentrated bioligands background gives mixed-ligand ternary complexes, which are more stable and related with storage of substance and transportationof metal ions in the life process.     

Synthesis and Crystal Structures of the α and β Forms of Bis （salicylaldoxime） copper （ Ⅱ ） Complexes

IntroductionSalicylaldoxime can be used in chemically modi-fied glassy-carbon electrodes,and applied to the deter-mination of metals in water.It shows a very high recov-ery[1,2].Direct design of solid-state structures that en-compass frameworks such as grids,ladders,helicesand channels of a desired architecture is central to crys-tal engineering science[3,4].Each of the oxidationstates of copper displays a different stereochemistry,ofwhich Cu(Ⅱ)is the most representative example foritsd9elec…     

Synthesis, Crystal Structure, Properties and Thermoanalysis of Complexes of Cu（Ⅱ） and Ni（Ⅱ） with Taurine-5-chlorosalicylaldelyde Schiff Base

The reactions of transition metal salts with taurine 5‐chlorosalicylaldelyde Schiff base gave two complexes [Ni(TCSSB)(H₂O)₃].H₂O (1) and [Cu(TCSSB)(H₂O)₂]₂[Cu(TCSSB)₂].6H₂O (2) (TCSSB=taurine‐5‐chlorosalicylaldelyde Schiff base), which were characterized by elemental analysis and X‐ray diffraction analysis. The complex 1 crystallized in monoclinic system with space group P2 ₁/c, and a=1.4816(2) nm, b=1.3953(2) nm, c= 0.7466(1) nm, β= 100.499(3)°, V=1.5176(4) nm³, Z=4, and an infinite 3‐D network structure was formed by hydrogen bonds among sulfo group, crystal water and coordinated water. Complex 2 crystallized in triclinic system with space group P1 , with the cell parameters: a = 0.6413(2) nm, b= 1.4596(3) nm, c= 1.6188(4) nm, a= 102.473(5)°, β= 98.979(4)°, γ=101.739°, V=1.4165(6) nm³, Z=1. The coordination environment between Cu(1) and Cu(2) is different. Cu(1) is slightly distorted square pyramidal while Cu(2) is distorted square‐plane. The complex 1 is mononuclear while the complex 2 is made up of two coordinated subunits, namely [Cu(TCSSB)₂] and [CU(TCSSB)(H₂O)₂]₂. Besides that the TG‐DTG of the complex 1 was analyzed, the thermal decomposition reaction of the complex was studied under a non‐isothermal condition by TG‐DTG. The TG and DTG curves indicate that the complex was decomposed in three stages: .     

Synthesis, Characterization, Spectroscopic and Electrochemical Properties of New Mono- and Binuclear Copper（Ⅰ） Complexes with Substituted 2,2′-Bipyridine

The mono- and binuclear Cu(Ⅰ) complexes with substituted 2,2′-bipyridine and iodide ligands, [CuL2]BF4(L=4-methoxycarbonyl-6-(4-methylphenyl)-2,2′-bipyridine (a), 6-(4-hydroxymethylphenyl)-2,2′-bipyridine (b) and 6-(4-methoxylphenyl)-2,2′-bipyridine (c)) and [Cu2(μ-I)2L2] were prepared, and the crystal structures of the complexes were obtained from signal-crystal X-ray diffractional analysis. The spectroscopic properties of the complexes in dichloromethane are dominated by low energy MLCT bands from 360 to 650 nrn. The electrochemical studies of mononuclear complexes reveal that the complexes have stable copper(Ⅰ) state.     

Synthesis and Structural Characterization of a New Cadmium（Ⅱ） Complex Bridged by Endo-norbornene-cis-5,6-dicarboxylic Acid

1 INTRODUCTION The construction of coordination polymers based on metal centers and multifunctional bri- dging ligands is of great interest currently owing to their novel topologies and potential applica- tions in magnetism, catalysis, molecular recogni- tion, ion exchange, small molecular inclusion, nonlinear optical behavior, electrical conductivity, molecular sensing, and, in general, the rational design of new materials[1～4]. As is well known, ligands containing carboxylate groups are…     

Synthesis and Characterization of aLead（Ⅱ）Complex with MicroporousStructure

1 INTRODUCTION Recently, much interest has been focused on various extended framework due to their intriguing architectures, new topologies and potential applications in microelectronics, nonlinear optics, molecular selection, ion exchange and catalysis[1~4] . In the last few years, a wide range of infinite structures with diverse topologies has been prepared by the reaction of metal ions with mulriple organic ligands[5～9]. However, up to now, much of the work has been concentrated on c…     

Synthesis, Crystal Structure and Antibacterial Activity of a New Ternary Copper（Ⅱ） Complex with 2,6-Pyridinedicarboxylic Acid and 1,10-Phenanthroline

A new ternary copper(II) complex,[C 43 H 27 Cu 2 N 7 O 5 ]·[C 14 H 6 CuN 2 O 8 ]·6.5H 2 O,has been synthesized by the reaction of copper sulfate,2,6-pyridinedicarboxylic acid and 1,10-phenanthroline (phen),and characterized by elemental analysis,IR,UV and X-ray single-crystal diffraction.It crystallizes in triclinic,space group P1,with a=14.379(5),b=15.510(5),c=15.835(6),α=78.567(6),β=63.594(6),γ=81.287(6)°,V=3092.1(19)3,C 57 H 46 Cu 3 N 9 O 19.5,M r=1359.54,Z=2,D c=1.446 Mg/m 3,λ(MoKα)=0.71073,μ=1.101 mm-1,F(000)=1362,S=1.071,the final R=0.0718 and wR=0.11960 for 10705 observer reflections (I > 2σ(I)).The structure unit of the title complex consists of a mononuclear part and a di-nuclear part,and the three copper ions show three coordination modes.Each 6-coordinated geometry of the Cu atom is a distorted octahedral coordination geometry.The 3D supramolecular system is formed by the hydrogen bond O-H···O and π-π stacking interaction between neighboring single cells.The antibacterial activity of the title complex is also studied.     

Synthesis and Structural Characterization of Mono-and Di-nuclear Zinc（ Ⅱ ） Coordination Compounds of Triphenylphosphoniopropionate

IntroductionThe coordination chemistry of zinc(Ⅱ)has beensubjected to extensive study in the past decades owingto its importance in life science[1].It has been foundthat zinc(Ⅱ)ions are crucially involved in the activesites of over300metalloenzymes and their role is notonly confined to catalysis and gene expression.Further-more,the presence of zinc(Ⅱ)helps to stabilize thetertiary and quaternary structures of proteins and nucle-ic acids[2—4].Like cadmium(Ⅱ),zinc(Ⅱ)is clearly amongthose m…     

Syntheses and Structural Characterization of Dimethyltin Complexs of N-（3-Methoxysalicylidene）-α-amino Acid

Three new dimethyltin complexes of N-(3-methoxysalicylidene)-α-amino acid,(CH3)2Sn(3-CH3O-2-OC6H3CH=NCHRCOO)(R = H,1;CH3,2;(CH3)2CH,3),have been synthe-sized by treating dimethyltin dichloride with the potassium salt of the ligand and characterized by elemental analysis,IR and 1H NMR spectra.The crystal structure of [(CH3)2Sn(3-CH3O-2-OC6H3CH=NCH2COO)(CH3OH)]2 H2O(1a),formed from methanol solution of 1,has been deter-mined.The crystal belongs to the monoclinic system,space group C/2c with a = 20.636(3),b = 7.8854(9),c = 20.668(2) ,β= 113.265(2)°,V = 3089.7(6) 3,Z = 4,Dc = 1.707 g/cm3,= 1.675 mm-1,F(000) = 1592,R = 0.0301 and wR = 0.0841.In complex 1a,the tin atom is six-coordinate and possesses a distorted [SnC2NO3] octahedral geometry with the two methyl groups occupying the trans positions.The weak Sn O interactions and intermolecular hydrogen bonds connected the molecules into an infinite chain.     

Synthesis and Crystal Structure of a Novel 1D Magnesium （Ⅱ） Coordination Polymer Constructed by L-Cysteic Acid

A novel coordination polymer [Mg(L)(H2O)2]·H2O] (LH2=L-cysteic acid) has been synthesized and characterized by elemental analysis, IR and single-crystal X-ray diffraction.The crystal crystallizes in orthorhombic system, space group P212121, with a=5.962(3), b=11.224(6), c=13.664(7)(A), V=914.3(8) (A)3, Z=4, Mr=245.50, Dc=1.783 g/cm3,μ=0.445 mm-1,flack parameter=0.32(16), F(000)=512, the final R=0.0458 and wR=0.1172 for 1578 observed reflections with I ＞ 2σ(Ⅰ). The Mg(Ⅱ) atom shows an octahedral geometry defined by two carboxyl O atoms from two different L-cysteic acid ligands, one carboxyl O atom and one amino N atom from the adjacent ligand, and two aqua ligands. The Mg(Ⅱ) atoms are bridged by L-cysteic acid ligands, leading to a 1D infinite zigzag chain. In the structure there are extensive hydrogen bonds,through which the complex completes its 3D framework structure.     

Synthesis and Characterization of Novel Orange-emitting Iridium（Ⅲ） Complexes with Diphenylquinoline Ligands Containing Fluorinated Substituent

Three new cyclometalated iridium（m） complexes based on ligands of diphenylquinoline with fluorinated subsfituents were prepared, and characterized by elemental analysis （EA）, ^1H NMR, and mass spectroscopy （MS）. The photophysical and electrophosphorescent properties of the complexes were briefly discussed.     

A Novel Cu(Ⅱ） Complex with 2,2′-Bipyridyl and L-Methioninate -synthesis,Characterization,Molecular Structure and Stability

The ternary Cu(II) complex with 2,2′‐bipyridyl (bipy) and L‐methioninate (L‐Met) has been synthesized and characterized by elemental analysis, molar conductivity, UV‐Vis spectra, IR spectra and pH‐potentiometric titration methods. The structure of the complex [Cu(L‐Met) (bipy) (H₂O)]ClO₄ · 3/8H₂O was characterized by the X‐ray diffraction analysis. It crystallizes in the triclinic system, space group P1 with four molecules in a unit cell of dimensions, a = 0.7656(2) nm, b = 1.3142(3) nm, c = 2.0596(4) nm, α = 97.70(3)°, β = 97.96(3)°, γ = 94.33(3)°, V= 2.0244(8) nm³, R₁, = 0.0441 and wR₂ = 0.0678. The crystal contains four crystllographically independent [Cu(L‐Met) (bipy) (H₂O)]⁺ complexes (Cu1—Cu4), having a distorted square‐pyramidal geometry with the same coordinated atoms around each copper center. The base plane is occupied by two nitrogen atoms of one bipy, the amino nitrogen atom and one carboxylate oxygen atom from each independent L‐Met moiety, and one water oxygen at an axial position. Cu1 and Cu3 are essentially enantiomers of Cu2 and Cu4. The four molecules are packed with each other by intermolecular hydrogen‐bonding and aromatic‐ring stacking interactions.     

One—and Two—photon Excited Fluorescence of Zinc（Ⅱ）,Cadmium（Ⅱ）Complexes Containing Phenothiazine Ligand

A new ligand,10-ethylphenothiazinyl-3-yl-methylene thiosemicarbazon(HL) and its complexes ML2 (M=Zn^2 ,Cd^2 ),which exhibit intensive two-photon excited (TPE) fluoresce at 800 nm laser pulses in femtosecond regime,were synthesized and characterized.The measured power dependence of the fluorescence signals provided direct evidence for TPE.All of them exhibited a large two-photon absorptive cross section and ,more importantly from the application point of view,high photochemical/photothermal stability.     

Synthesis and Characterization of New Macrocyclic Cu（Ⅱ） Complexes from Various Diamines, Copper（Ⅱ） Nitrate and 1,4-Bis（2-formylphenoxy）butane

Six new macrocyclic complexes were synthesized by a template reaction of 1,4-bis（2-formylphenoxy）butane with diamines and Cu（NO3）2·3H2O and their structures were proposed on the basis of elemental analysis, FT-IR, UV-Vis, magnetic susceptibility measurements, molar conductivity measurements and mass spectra. The metal to ligand molar ratios of the Cu（Ⅱ） complexes were found to be 1 ： 1. The Cu（Ⅱ） complexes are 1 ： 2 electrolytes as shown by their molar conductivities （∧m） in DMF at 10^-3 mol·L^-1. Due to the existence of free ions the Cu（Ⅱ） complexes are electrically conductive. Their configurations were proposed to be probably distorted octahedral.