Phlomoside D — an iridoid glycoside fromPhlomis regelii

A new iridoid – phlomoside D- has been isolated from the epigeal organs ofPhlomis regelii (M. Pop). Its structure has been established on the basis of chemical transformations and spectral characteristics.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89 14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 551–553, July–August, 1996. Original article submitted February 5, 1996.     

Berberis Alkaloids XXXVIII. Turcamine — A new isoquinoline alkaloid fromBerberis turcomanica

The new isoquinoline alkaloid turcamine (1) has been isolated from the leaves ofBerberis turcomanica, and its structure has been established as 8-hydroxy-7-methoxy-2-methyltetrahydroisoquinoline. A relationship has been found between a substituent at C-8 and the multiplicities of the signals from C-5 and C-6.Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 894–896, November–December, 1996. Original article submitted April 15, 1996.     

Phlomoside C — an iridoid glycoside fromPhlomis regelii

A new iridoid — phlomoside C — has been isolated from the epigeal part ofPhlomis regelii M. Pop. Its structure has been established on the basis of spectral characteristics and chemical transformations.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89 14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 554–557, July–August, 1996. Original article submitted February 5, 1996.     

Berberis alkaloids XXXVI. Turcomanidine — A new alkaloid fromBerberis turcomanica

The alkaloid composition of the leaves ofBerberis turcomanica has been studied. Together with known 1-benzylisoquinoline alkaloids, we isolated a new one — turcomanidine, the structure of which has been established by chemical transformations and a study of spectral characteristics. Of the known alkaloids, N-methylcorydaldine has been detected in plants of the Berberis genus for the first time.Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 885–888, November–December, 1996. Original article submitted March 4, 1996.     

Detection of diol lipids in plants of the Elaeagnaceae family and the properties of their synthetic analogs

The compositions of the alcohols of the triacylglycerol fraction of the fruit ofHippophae rhamnoides and of the seeds ofElaeagnus angustifolia have been determined. The behavior under the action of pancreatic lipase of synthetic analogs of the diol compounds detected has been studied.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89 14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 697–700, September–October, 1996. Original article submitted February 12, 1996.     

Alkaloid content ofCodonopsis clematidea

The alkaloids ofCodonopsis clematidea Schrenk. from nine growth sites have been studied. Plants from the Kashkadar'inskaya Oblast and the Darvaza range in Tadzhikistan were distinguished by the highest level of the desired alkaloid codonopsine.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89 14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 580–582, July–August, 1996. Original article submitted February 19, 1996.     

Lipids of the vegetative and generative organs ofHibiscus sp.

The lipids of the leaves, stems, and roots ofHibiscus sp. have been studied. Their fatty acid compositions have been determined. The greatest amount of unsaturated fatty acids was present in the glycolipids of the leaves and the stems. More than 25% of low-molecular-mass C₁₀-C₁₂ fatty acids have been found in the neutral lipids of the roots.Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 705–708, September–October, 1996. Original article submitted March 11, 1996.     

Study of structure-activity relationships in a series of alkaloids ofAconitum zeravschanicum and their analogs

The toxic and antiarrhythmic activities of diterpene alkaloids fromAconitum zeravschanicum and their synthetic analogs have been investigated. It has been established that, in the series of compounds studied, activity and toxicity depend on the type of skeleton, the nature and positions of substituents, and the basicity of the nitrogen atom.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89 14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 384–387, May–June, 1996. Original article submitted February 26, 1996.     

Plant polysaccharides XVI. Mannan fromUngernia ferganica and its biological activity

A mannan has been isolated from the bulbs ofUngernia ferganica Vved., and its qualitative chemical composition, the nature of the bond between the hexose residues, and the form of the molecule have been determined. It has been established that the mannan is a relatively nontoxic compound and exhibits a pronounced hypolipidemic activity both in intact animals and in animals with experimental hyperlipidemia.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkennt, fax (3712) 89 14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 690–692, September–October, 1996. Original article submitted February 14, 1996.     

Robustaminecis-N-oxide and merenderine fromMerendera robusta

The structure and configuration of a new homoproaporphine, robustamine cis-N-oxide, isolated fromMerendera robusta (fam. Liliaceae) have been established by spectral characteristics and chemical transformations. It was found that the fraction of alkali-soluble bases from this plant consists mainly of the homoaporphine compound merenderine, the amount of which increases considerably towards the end of the vegetation period.Tashkent State University, fax (3712) 46 24 72. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 734–738, September–October, 1996. Original article submitted February 26, 1996.     

Pheromones of insects and their analogs LIII. Synthesis of ferrulactone I —a pheromone ofCryptolestes ferrugineus

8-Acetoxy-3, 7-dimethyl-l-(phenylsulfonylacetoxy)octa-2E, 6E-diene has been synthesized, and its cyclization under the action of zerovalent palladium followed by desulfurization with the aid of sodium amalgam has led to ferrulactone I — one of the macrolide components of the aggregation pheromone of the rust-red grain beetle (Cryptolestes ferrugineus).Institute of Organic Chemistry, Urals Scientific Center of the Russian Academy of Sciences, 450054, Ufa pr. Oktyabrya, 71. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 932–935, November–December, 1996. Original article submitted May 27, 1996.     

Phlomoside B - An iridoid glycoside fromPhlomis regelii

A new iridoid — phlomoside B — has been isolated from the epigeal part of the plantPhlomis regelii (M. Pop.). Its structure has been established on the basis of spectral investigations and chemical transformations.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89 14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 46–49, January–February, 1996. Original article submitted September 17, 1995.     

Extraction of zinc(ii) from aqueous alkali solutions byortho-derivatives of phenols

The ability of a series of ortho-functionalized phenol derivatives and ofN-(2-hydroximinocyclohexyl)palmitohydroxamic acid to extract Zn²⁺ ions from aqueous alkali solutions (0.2–4.0 mol L^–1) in the presence of trialkylmethylammonium methylsulfate has been investigated. The most active extractants are chelating phenols containing N- and S-coordinating groups and chelates of the pyrocatechol series.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 1279–1281, May, 1996.     

Qualitative mass spectrometric analysis of the total diterpene bases from the roots ofAconitum kusnezoffi

A quantitative analysis of the roots ofAconitum kusnezoffi has been made by a group of mass-spectrometric methods. Twelve diterpene bases have been studied of which ten have been identified as beiwutine, aconitine. mesaconitine, 3-deoxyaconitine, hypaconitine, neoline, songorine, isotalatisidine, talatisidine, and 10-hydroxyneoline.Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 89–92, January–February, 1996. Original article submitted August 7, 1995.     

Tropane alkaloids of two species of plants of theConvolvulus genus

Eighteen alkaloids have been isolated from two species ofConvolvulus, ten of which were new. The structures of nine of the latter, including two dimeric bases, have been established. Transitions between them have been effected.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89 14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 687–689, September–October, 1986. Original article submitted February 19, 1996.     

Berberis alkaloids. XXXIV. Turcomanine — a new alkaloid fromBerberis turcomanica

Absttract Berberine, isocorydine, glaucine, thalicmidine, aromoline, oxyacanthine, and the new 1-benzylisoquinoline alkaloid turcomanine have been isolated fromBerberis turcomanica Kar. The structure of the new alkaloid has been established on the basis of chemical transformations and spectral characteristics. This is the first time that isocorydine, thalicmidine, aromoline, and oxyacanthine have been isolated from this plant.Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 74–76, January–February, 1996. Original article submitted May 22, 1995.     

Pectin substances ofAmaranthus cruentus

Pectin substances have been isolated from the epigeal pan of love-lies-bleeding,Amaranthus cruentus (A. caudatus), and have been characterized. The presence in them of galacturonic acid, galactose, rhamnose, xylose, arabinose, fructose, and glucose residues has been established. The titrimetric indices of the substances isolated have been determined and they have been studied by IR spectroscopy.Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 7–9, January–February, 1996. Original article submitted August 14, 1995.     

Isolation of hispidin from a walnut-tree fungus and its antioxidant activity

An -styrylpyrone derivative — hispidin — has been isolated from a walnut-tree fungus. Its antioxidant activity has been studied inin vitro andin vivo experiments on animals of different ages.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 89 14 75. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 34–37, January–February, 1996. Original article submitted November 3, 1995.     

Synthesis and chemical reactions of 2-RS-methyl-7-methyl-5-oxo-5H-1,3,4-thiadiazolo[3,2-a]pyrimidines

The corresponding sulfides have been synthesized starting from 2-chloromethyl-7-methyl-5-oxo-5H-1,3,4-thiadiazolo[3,2-a]pyrimidine and some of their reactions have been studied.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 549–552, April, 1996.     

Cardenolide glycosides ofCheiranthus allioni. XVI. Neoevonoside and cellobiosyl-digigulomethyloside

Another three isomeric glycosides have been isolated from the seeds ofCheiranthus allioni Hort., two of which are new: after their chemical structures were determined they were named neoevonoside and cellobiosyl-digigulomethyloside.State Scientific Center for Drugs of the Academy of Sciences and the Ministry of Health of the Ukraine, 310085, Kharkov, ul. Astronomicheskaya, 33. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 66–69, January–February, 1996. Original article submitted May 22, 1995.