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Benjamin Brennecke Qinghua Wang Qingyang Zhang Hai‐Yu Hu Marc Nazar 《Angewandte Chemie (International ed. in English)》2020,59(22):8512-8516
Herein we report the development of a turn‐on lanthanide luminescent probe for time‐gated detection of nitroreductases (NTRs) in live bacteria. The probe is activated through NTR‐induced formation of the sensitizing carbostyril antenna and resulting energy transfer to the lanthanide center. This novel NTR‐responsive trigger is virtually non‐fluorescent in its inactivated form and features a large signal increase upon activation. We show that the probe is capable of selectively sensing NTR in lysates as well as in live bacteria of the ESKAPE family which are clinically highly relevant multiresistant pathogens responsible for the majority of hospital infections. The results suggest that our probe could be used to develop diagnostic tools for bacterial infections. 相似文献
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Back Cover: Polynuclear SmIII Polyamidoamine‐Based Dendrimer: A Single Probe for Combined Visible and Near‐Infrared Live‐Cell Imaging (Angew. Chem. Int. Ed. 11/2014) 下载免费PDF全文
Dr. Alexandra Foucault‐Collet Dr. Chad M. Shade Iuliia Nazarenko Prof. Dr. Stéphane Petoud Dr. Svetlana V. Eliseeva 《Angewandte Chemie (International ed. in English)》2014,53(11):3034-3034
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Back Cover: Single‐Nanoparticle Cell Barcoding by Tunable FRET from Lanthanides to Quantum Dots (Angew. Chem. Int. Ed. 41/2018) 下载免费PDF全文
Chi Chen Dr. Lijiao Ao Yu‐Tang Wu Vjona Cifliku Dr. Marcelina Cardoso Dos Santos Emmanuel Bourrier Dr. Martina Delbianco Prof. David Parker Dr. Jurriaan M. Zwier Dr. Liang Huang Prof. Niko Hildebrandt 《Angewandte Chemie (International ed. in English)》2018,57(41):13692-13692
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Cover Picture: Dinuclear Ruthenium(II) Complexes as Two‐Photon,Time‐Resolved Emission Microscopy Probes for Cellular DNA (Angew. Chem. Int. Ed. 13/2014) 下载免费PDF全文
Dr. Elizabeth Baggaley Dr. Martin R. Gill Dr. Nicola H. Green Dr. David Turton Dr. Igor V. Sazanovich Prof. Stanley W. Botchway Prof. Carl Smythe Prof. John W. Haycock Dr. Julia A. Weinstein Dr. Jim A. Thomas 《Angewandte Chemie (International ed. in English)》2014,53(13):3283-3283
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Back Cover: Efficient Luminescence from Fluorene‐ and Spirobifluorene‐Based Lanthanide Complexes upon Near‐Visible Irradiation (Chem. Eur. J. 16/2014) 下载免费PDF全文
Dr. Gregorio Bottaro Dr. Fabio Rizzo Dr. Marco Cavazzini Dr. Lidia Armelao Dr. Silvio Quici 《Chemistry (Weinheim an der Bergstrasse, Germany)》2014,20(16):4840-4840
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