A New Bibenzyl Derivative from Dendrobium moniliforme

A new bibenzyl derivative,3,4-dihydroxy-4′,5-dimethoxy bibenzyl,was isolated from a orchid Dendrobium moniliforme. The structure elucidation and ^1H,^13C NMR assignments were achieved by spectroscopic method.     

New Bibenzyl and Phenanthrenedione from Dendrobium densiflorum

Several species of Dendrobium plants (Orchidaceae) are used in traditional Chinesemedicine as a Yin tonic to nourish the stomach, promote the production of body fluid,and reduce feverl. Chemical components of several Dendrobium plants have been widelyinvestigated" 3. D. densytorum Lindl. ex Wall. is one species of Dendrobium plants,several components of this species have been reported before" 5. We herein reportstructural elucidation of a new bibenzyl named densiflorol A 1 and a newphenant…     

A new 9,10-dihydrophenanthrene from Dendrobium moniliforme

A new 9,10-dihydrophenanthrene,1,5-dihydroxy-3,4,7-trimethoxy-9,10-dihydrophenanthrene (1) was isolated and identified from the whole plants of Dendrobium moniliforme, as well as 24 known compounds including hircinol (2), (2R^*,3S^*)-3-hydroxymethyl-9-methoxy-2-(4′-hydroxy-3′,5′-dimethoxyphenyl)-2,3,6,7-tetrahydro-phenanthro[4,3-b]furan-5,11-diol (3), diospyrosin (4), aloifol I (5), moscatilin (6), 3,4′-dihydroxy-3′,4,5-trimethoxybibenzyl (7), gigantol (8), 3,3′-dihydroxy-4,5-dimethoxybibenzyl (9), longicornuol A (10), N-trans-cinnamoyltyramine (11), paprazine (12), N-trans-feruloyl 3′-O-methyldopamine (13), moupinamide (14), dihydroconiferyl dihydro-p-coumarate (15), dihydrosinapyl dihydro-p-coumarate (16), 3-isopropyl-5-acetoxycyclohexene-2-one-1 (17), p-hydroxybenzaldehyde (18), vanillin (19), p-hydroxyphenylpropionic acid (20), vanillic acid (21), protocatechuic acid (22), (+)-syringaresinol (23), β-sitosterol (24) and daucosterol (25). Compounds 3, 4, 13, 16, 17 and 20 were isolated from the Dendrobium genus for the first time, and compounds 2, 5, 7, 9–12, 14, 15, 18, 21 and 22 were originally obtained from D. moniliforme.     

A New Picrotoxane Type Sesquiterpene from Dendrobium densiflorum

A new picrotoxane type sesquiterpene named dendrodensiflorol has been isolated from the stems of Dendrobium densiflorum. Its structure was identified on the basis of spectroscopic method.     

A new Dendrobine-Type Alkaloid from Dendrobium nobile

A new dendrobine-type alkaloid has been isolated from stems of Dendrobium nobile lindl.Its structure has been identified on the basis of spectroscopic method.     

A New Dihydroflavone Glycoside from Glycyrrhiza uralensis

A new dihydroflavone glycoside was isolated from the underground parts of Glycyrrhiza uralensis. Its structure was elucidated as 7-hydroxyl-4′-O-]3-D-(6″-O-α-hydroxylpropionyl) glucopyranosyl dihydroflavone by spectral methods.     

A Novel Pregnane Glycoside from Biondia chinensis

A novel pregnane glycoside, biondianoside E, was isolated from the roots of Biondia chinensis. By the spectroscopic and chemical methods, this structure was elucidated as 3β, 5β,14β, 20S, 21-pentahydroxypregnane 3-O-β-D-glucopyranosyl-(1→4)-β-D-cymaropyranoside.     

A New Bianthraqinonc Glycoside from Eremurus chinensis

Eremurus chinensis Fedtch has a wide distribution in the western part of China; it hasbeen used in Chinese folk medicine for the treatment of rheumatism and physicalweaknessl. Only few reports describe polysaccharides'-' rather than other chemicalconstituents from the genus Eremurus. We report here the isolation and structuralelucidation of a new bianthraquinone glycoside, 8-O- P -D-glucopyranosyl-2,7'-hi(l,8dihydroxy-3-methyl-9,10-anthraqu 1 from E. chinensis.The EtOAc soluble fraction ob…     

A new (propylphenyl)bibenzyl derivative from Dendrobium williamsonii

A new (propylphenyl)bibenzyl derivative, dendrowillol A (1), along with 22 known compounds were isolated from the whole plants of Dendrobium williamsonii. Their structures were elucidated by means of extensive spectroscopic analysis. Cytotoxicity evaluation against five human tumour lines showed that all the compounds tested displayed very weak cytotoxicity when compared with the positive control taxol, but selective inhibitory effects on HL-60 for several compounds tested were observed, with IC₅₀ values ranging from 4.48 to 11.04 μM.     

Paeonivayin, A New Monoterpene Glycoside from Paeonia delavayi

Paeoniarootbark,"Dan-Pi"inChinese,isoneofthemostimportantherbaldrugswhichhasbeenusedfortreatmentofmuscularspasm,chestpains,diarrhoea,bloodandliverdisordersaswellasageneralanalgesicintraditionalChinesemedicine.SignificantchemicalandpharmacologicalinvestigationshavebeenconductedonthedifferentspeciesofPaeonia'-',P.albifiora,P.anomala,P.lacli/loraandP.sloffflllicosa.Asoneofthemainsourcesof"Dan-Pi",theconstituentsofP.delayal'iFranch.havenotbeenstudied.Inthecourseofourstudyonpharmacologicallyac…     

A New Phenylpropanoid Glycoside: Serratumoside A from Clerodendrum serratum

In the previous papers"', we have reported some chemical constituents fromClerodendrum serratum var. amplerghlium Moldenke. A continuation of our studies onthe same plant led to the isolation of a new phenylpropanoid, serratumoside A (l), whichis reported in this paper.Serratumoside A (l) with three known phenylpropanoid glycosides identified asacteoside', mwtinoside' and myricoside', respectively, were isolated from the Cserratum. Compound I was isolated as a brown amorphous powder, laly …     

A New Monoterpene Glycoside from Paeonia veitchii

The root cortex of Paeonia veitchii Lynch. is one of the most important crude drugs in Chinese traditional medicine. It is used as an analgesic, sedative, anti-inflammatory agent and a remedy for cardiovascular, extravasated blood1. The present paper deals with the structural elucidation of a new compound from this material. Compound 1, obtained as viscous oil, gave a quasi-molecular ion peak at m/z 521 [M-1]- in the negative FAB-MS, which was 42 amu greater than that of paeon…     

A New Monoterpene Glycoside from Swertia punicea

The plant Swerlia punicea Hemsl. (Gentianaceae), distributed in Southwest China, isused in Chinese medicine for acute bilious hepatitis and cholecystitis'. Previousinvestigations of this plant have led the isolation of various compounds'. In thisinvestigation, seven compounds were isolated tyom the whole plants of S. punicea,collected in E-Shan, Yunnan Province in July, 1997 and identified by P. Y. Bet inKunming institUte of Botany, Chinese Academy of Sciences, where the specimen isdep…     

A New Antimicrobial Flavonol Glycoside from Alchornea Davidii

A new flavonol glycoside,isorhamnetin-3-O- β-D-xyloside,was isolated from the extract of leaves and twigs of Alchornea davidii (Euphorbiaceae).Its structure was established on the basis of the spectral analysis and chemical degradation.Antimicrobial assay showed that it moderately inhibited the growth of test bacteria (Staphylocoocu aureus,Bacillus subtilis and Pseudomonas fluorescens)and fungi (Candida albicans,Aspergillus niger and Trichophyton rubrum) with MICs at 50μg/ml.     

A New Pregnane Glycoside from Fermented Leaves of Agave americana

A new minor pregane glycoside was isolated from the fermented leaves of Agave americana.Its structure was elucidated as (20S)-5α-pregnane-3β，20-diol 20-O-β-D-glucopyrano-side(1)by spectral methods.     

A New Neolignan Glycoside from Pedicularis armata

A new neolignan glycoside named armaoside (1) was isolated from the whole plant of Pedicularis armata Maxim. Its structure was elucidated by spectroscopic and chemical methods. Antibacterial assay showed that it has moderately antibacterial activities against Eschecichia coli, Bacillus subtilis and Staphylococcus aureus.     

A New Flavanone and a New Flavanone Glycoside from ScuteUaria baicalensis

A new flavanone （2S）-5, 7, 2＇, 5＇-tetrahydroxy-flavanone 1 together with a new flavanone glycoside （2S）-5, 7, 2＇, 5＇-tetrahydroxy-flavanone 7-O-13-D-glucopyranoside 2, were isolated from the dry roots of Scutellaria baicalensis. Their structures were elucidated on the basis of spectroscopic data.     

A New Biphenyl Glycoside from the Leaves of Eriobotrya japonica

The leaves of Eriobotrya japonica (Thunb.) Lindl (Rosaceae) have been widely used as a folk medicine (known as “Pipaye”) to treat stomachache and promote antitussive, anti-inflammatory and diuretic effects in China. A number of triterpenoids1,2, sesquit…     

A New Bianthraqinone Glycoside from Eremurus chinensis

A new bianthraquinone glycoside, 8-O-β-D-glucopyranosyl-2,7'-bi(1,8-dihydroxy-3-methyl-9,10-anthraquinonyl) 1 was isolated from Eremurus chinensis Fedtch. Its structure was established by spectroscopic techniques including 2D-NMR and chemical methods.