共查询到20条相似文献,搜索用时 31 毫秒
1.
A. V. Butin T. A. Stroganova V. G. Kul'nevich 《Chemistry of Heterocyclic Compounds》1999,35(7):757-787
The literature data on furyl(aryl)methanes are systematized and analyzed for the first time. Results obtained by the authors on the synthesis, reactions, and application of these compounds are reviewed.Kuban State Technological University, Krasnodar 350072, Russia; Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 867–901, July, 1999. 相似文献
2.
M. Dabiri P. Salehi M. Baghbanzadeh M. Shakouri S. Otokesh T. Ekrami R. Doosti 《Journal of the Iranian Chemical Society》2007,4(4):393-401
Dihydropyrimidinones, bis(indolyl)methanes, and N-alkyl and N-arylimides were synthesized efficiently under mild reaction conditions in the presence of two types of ionic liquids. In each section, effects of different ILs on the yield of reactions were investigated. The use of ionic liquids offer improvements for the synthesis of title compounds with regard to the yield of products, simplicity in operation, short reaction times and green aspects by avoiding toxic catalyst and organic solvents. 相似文献
3.
N. G. Mikhailyuchenko A. V. Butin V. E. Zavodnik V. G. Kul'nevich 《Chemistry of Heterocyclic Compounds》1993,29(6):642-649
The reaction of polyfuryl(aryl)methanes with N-(3,5-dichlorophenyl)maleimide has been studied. It was found that tetrasubstituted methanes do not react. Difurylmethane, gem-difurylethane, gem-difurylethane, and trifurylmethane form mono- and diadducts, and difurylarylmethanes form only monoadducts. The molecular and crystal structure of the diadduct of gem-difurylethane- gem-bis {4-aza-7-methyl-10-oxa-4-(3,5-dichlorophenyl)tricyclo-[5,2,1,0 2,6]deca-8-en-3,5-dion-1-yl}ethane has been studied.For Communication 8, see [1].Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 751–758, June, 1993. 相似文献
4.
在酸性离子液体催化下,通过吲哚及其衍生物和吲哚甲醛反应合成了一系列三吲哚甲烷化合物。[hmim]HSO4/EtOH 对于该反应来说,是一个高效、绿色的催化体系。 相似文献
5.
N. S. Prostakov V. I. Kuznetsov A. A. Savina M. A. Ryashentseva V. P. Zvolinskii 《Chemistry of Heterocyclic Compounds》1977,13(5):522-526
Aryl(6-methyl-2-phenyl-7-indolizinyl)methanes were obtained by quaternization of aryl(-pyridyl)methanes with bromoacetophenone and subsequent cyclization of the quaternary salts with 40% potassium carbonate solution (the Chichibabin method). The stable 2, 5-dimethyl-4-(2,4-dimethylbenzyl)pyridinium benzoylmethylid, which was converted to an indolizine by the action of Al2O3, was isolated by the action of a 10% potassium carbonate solution on the corresponding quaternary salt. The ability of 3-unsubstituted indolizines to undergo protonation in both the 3 and 1 position was shown on the basis of the PMR spectra. The aryl(7-indolizinyl)methanes are selectively hydrogenated thoroughly over rhenium heptasulfide in the indolizine ring to give tetra or octahydro derivatives without involvement of the aryl groups. Data from the IR, PMR, and mass spectra are presented.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 646–649, May, 1977. 相似文献
6.
Manickam Bakthadoss Anthonisamy Devaraj Jayakumar Srinivasan 《Journal of heterocyclic chemistry》2015,52(2):418-424
In this article, a simple method for the synthesis of bis(di(indolyl)aryl)methanes is described. The iodine‐catalyzed (5 mol %) reaction of indoles with various bis(salicylaldehyde) derivatives affords the bis(di(indolyl)aryl)methanes in excellent yields. The reaction works well under mild reaction condition with shorter reaction time. 相似文献
7.
Direct arylation of aryl(azaaryl)methanes with aryl halides takes place at the benzylic position in the presence of a hydroxide base under palladium catalysis to yield triarylmethanes. 相似文献
8.
Akın Baysal Murat Aydemir Feyyaz Durap Bahattin Gümgüm Saim Özkar Leyla Tatar Yıldırım 《Polyhedron》2007
New bis(phosphinoamine) and bis(phosphinite) derivatives of 2,2′-bipyridine were prepared through a single step reaction of 3,3′-diamino-2,2′-bipyridine or 3,3′-dihydroxy-2,2′-bipyridine with diphenylchlorophosphine, respectively. Their P = E chalcogenides (E = O, S, Se) were also prepared. All the new compounds were characterized by elemental analysis, IR and NMR spectroscopies. The molecular structure of 3,3′-bis(diphenylthiophosphinite)-2,2′-bipyridine was elucidated by single-crystal X-ray crystallography. 相似文献
9.
Trialkylsilylmethyltris (hydroxymethyl) methanes were synthesized by the reaction of -trialkylsilylpropanals with formaldehyde.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 12, pp. 2860–2861, December, 1989. 相似文献
10.
In an effort to develop an efficient synthetic method of highly diastereoselective (2′R)- and (2′S)-2′-deoxy[2′-2H]guanosines, chemoenzymatic conversion was investigated. The synthesis of (2′R > 98% de)-2′-deoxy[2′-2H]guanosine was achieved by biological transdeoxyribosylation using (2′R > 98% de)-2′-deoxy[2′-2H]uridine, 2,6-diaminopurine, and Enterobacter aerogenes AJ-11125, followed by treatment with adenosine deaminase. (2′S > 98% de)-2′-Deoxy[2′-2H]guanosine was synthesized from (2′S > 98% de)-2′-deoxy[2′-2H]uridine and 2,6-diaminopurine using thymidine phosphorylase and purine nucleoside phosphorylase instead of E. aerogenes AJ-11125. 相似文献
11.
Da-Wei Zhang Yu-Min Zhang Yi-Liang Zhang Tian-Qi Zhao Hong-Wei Liu Yuan-Ming Gan Qiang Gu 《Chemical Papers》2015,69(3):470-478
An efficient synthesis of bis(indolyl)methanes was developed. Bis(indolyl)methanes were synthesized starting from various aromatic aldehydes with indole under microwave irradiation and solvent-free conditions (85–98 %). Solid support SiO2 was found to possess favorable catalytic and dispersancy parameters for the condensation reaction. Moreover, novel bis(indolyl)methanes containing an isoxazole ring were synthesized via this method in excellent yields (> 94 %) using 3-substituted isoxazole-5-carbaldehydes and indole. 相似文献
12.
A simple and highly efficient green protocol for synthesis of bis(indolyl)methanes was carried out by the reaction of indole with aldehydes and ketones in the presence of FeCl3?based ionic liquid. These liquids serve as efficient media as well as Lewis acid catalysts. 相似文献
13.
Iran Sheikhshoaie Hojatollah Khabazzadeh Samira Saeid-Nia 《Transition Metal Chemistry》2009,34(5):463-466
[Fe(III)(salen)]Cl (salen = N,N′-ethylenebis(salicylimine)) is an efficient catalyst for the electrophilic substitution of
indole with carbonyl compounds to afford the corresponding bis(indolyl)methanes in good yields in molten tetrabutylammonium
bromide as an ionic liquid. Notable features of this new procedure are shorter reaction times, cleaner reaction profiles,
and simple experimental and work-up procedures. 相似文献
14.
Qiong Ji YaoZaher M.A. Judeh 《Tetrahedron》2011,67(22):4086-4092
The preparation of new chiral 1,3-diamine ligand systems based on the 1,1′-methylene-bis(1,1′,2,2′,3,3′,4,4′-octahydroisoquinoline) framework is described. Synthesis of various mono-, di-, and bridged N-alkyl derivatives are presented. Resolution of one compound, its Cu(I)Br X-ray crystallographic structure and the preliminary results on its application in the enantioselective Henry and Aldol reactions are disclosed. 相似文献
15.
2′,3′,4′,5′-Tetraacetyl-N(3)-carboxymethylriboflavin derivatives: synthesis and fluorescence studies
Christian Banekovich 《Tetrahedron letters》2005,46(30):5053-5056
The hitherto not described 2′,3′,4′,5′-tetraacetyl-N(3)-carboxymethylriboflavin (1) could be prepared starting from 2′,3′,4′,5′-tetraacetylriboflavin by alkylation with tert-butyl α-bromoacetate and benzyl α-bromoacetate, followed by deprotection reaction. The results of fluorescence studies are described. 相似文献
16.
Mamoru Hyodo 《Tetrahedron》2006,62(13):3089-3094
This paper reports the synthesis of cyclic bis(3′-5′)diguanylic acid (c-di-GMP) analogs, including the monophosphorothioic acid of c-di-GMP (c-GpGps), cyclic bis(3′-5′)guanylic/adenylic acid (c-GpAp), and cyclic bis(3′-5′)guanylic/inosinic acid (c-GpIp). These compounds are expected to be important, both in elucidating the mechanism of bioactive c-di-GMP and in designing and creating new bioactive c-di-GMP-related artificial derivatives. 相似文献
17.
The antiviral nucleoside 3′-α-fluoro-2′,3′-dideoxyguanosine (FddG) was synthesized via 3′-α-selective fluorination of 8,2′-thioanhydronucleoside as the key step. Desulfurization of 3′-α-fluoro-3′-deoxy-8,2′-thioanhydronucleoside could be achieved by the treatment with Raney Ni in toluene. This method provides a concise route to 3′-α-fluoro-2′,3′-dideoxynucleosides that avoids the use of explosive and expensive SF4-related fluorinating reagents. 相似文献
18.
A new 5′-O-AZT prodrug was synthesized by conjugating 3′-azido-2′,3′-dideoxythymidine (AZT) with poly(oxyethylene H-phosphonate) at room temperature under Atherton-Todd reaction conditions. The acute toxicity of poly(5′-O-AZT-oxyethylene phosphate) was reduced significantly in comparison with non-immobilized AZT. 相似文献
19.
Omar Mouhtady 《Tetrahedron letters》2006,47(25):4125-4128
The new (R)-6,6′-bis(trifluoromethanesulfonyl)-2,2′-dihydroxy-1,1′-binaphthyl (1) has been synthesized and proved to generate highly active zirconium-based catalysts for asymmetric Mannich-type reactions. 相似文献
20.
Pierre M.J. Jung Renaud BeaudegniesAlain De Mesmaeker Sebastian Wendeborn 《Tetrahedron letters》2003,44(2):293-297
A short, efficient synthesis of 5′-amino-5′-(S)-methyl-2′,5′-dideoxynucleosides 1 has been developed through the diastereoselective addition of methylmagnesium bromide or methyllithium to an intermediate tert-butylsulfinimide. 相似文献