共查询到20条相似文献,搜索用时 875 毫秒
1.
Kamiran Sarac Cahit Orek Ahmet Cetin Taner Dastan Sevgi Durna Dastan 《Phosphorus, sulfur, and silicon and the related elements》2016,191(9):1284-1289
Diamines were added to arylaldehydes in ethanol, which resulted in corresponding diimines. Novel bis-1-aminophosphinic acid compounds were synthesized through the interaction of diimines and hypophosphorous acid. The new compounds were characterized by elemental analyses, FT-IR and 1H, 13C and 31P NMR techniques. The in vitro antioxidant activity of the newly synthesized compounds were measured and found to exhibit significantly higher antioxidant activity than the standard. 相似文献
2.
Xuewen Hua Wutao Mao Zhijin Fan Xiaotian Ji Fengyun Li Guangning Zong Haibin Song Kalinina Tatiana Yury Yu. Morzherin Nataliya P. Belskaya Vasiliy A. Bakulev 《Journal of heterocyclic chemistry》2016,53(3):865-875
Three series of new anthranilic diamide derivatives containing sulfide, N‐cyanomethylsulfilimine, and N‐cyanomethylsulfoximine groups were designed and synthesized by combining the active substructures of anthranilic diamides and sulfoxaflor. The structures of all newly synthesized compounds were confirmed by IR and 1H/13C‐NMR, and some of them were confirmed by elemental analysis or HRMS too. The synthesized compounds were screened for their insecticidal and fungicidal activities. Bioasssay results indicated that some of the synthesized compounds possessed certain degrees of insecticidal activity against Mythimna separata. However, some compounds exhibited good fungicidal activity against Sclerotinia sclerotiorum. 相似文献
3.
Fused 3,6‐disubstituted triazolothiadiazoles were synthesized in good yield from a rapid and convenient oxidative cyclization of N‐heteroaryl‐substituted hydrazones promoted by chloramine‐T trihydrate at ambient temperature. The structure of the synthesized compounds was confirmed by FTIR, 1H NMR, 13C NMR, and mass spectral data. The synthesized compounds were evaluated for their antioxidant and antitubercular activities. All the compounds 5a‐i and 6a‐i showed good antitubercular activity. However, only compounds 5a‐i showed good antioxidant activity. 相似文献
4.
Lingappa Malleshaa Kikkeri N.Mohana Devaraju Rakshith Sreedharamurthy Satishb 《中国化学》2011,29(1):102-108
A series of 2‐methyl‐5‐nitroaniline derivatives, 5a – 5k and 6a – 6f , were synthesized in order to determine their in vitro antimicrobial activity. The chemical structures of the synthesized compounds were confirmed by elemental analyses, UV‐visible, FT‐IR, 1H NMR and 13C NMR spectral studies. The structure‐activity relationships of the synthesized compounds were also discussed. Among the synthesized compounds, 5f , 5d , 6b and 6e showed good antimicrobial activity compared to standard drugs. 相似文献
5.
Synthesis,Spectral Characterization,and Antimicrobial Activity of Novel 2,4,6‐Trisubstituted Quinazoline Derivatives by Buchwald and Suzuki Coupling Reactions 下载免费PDF全文
Kotla Veena Vani Garlapati Ramesh Chunduri Venkata Rao 《Journal of heterocyclic chemistry》2016,53(5):1528-1533
A series of novel 2,4,6‐trisubstituted quinazoline derivatives were synthesized starting from 2‐amino‐5‐bromobenzoic acid. The structures of the newly synthesized compounds were established by IR, 1H NMR, 13C NMR, and mass spectral data. All the compounds were tested for antimicrobial activity. 相似文献
6.
Amir Adabi Ardakani Hadi Kargar Nourollah Feizi Muhammad Nawaz Tahir 《Journal of the Iranian Chemical Society》2018,15(7):1495-1504
A series of Schiff base compounds were synthesized by the reaction of different 3,5-dihalosalicylaldehyde (halo atoms equal to Cl, Br and I) with polymethylenediamines of varying chain length. The Schiff bases were characterized using FT-IR, UV–Vis, 1H NMR, 13C NMR and mass spectroscopic techniques, and elemental analyses (CHN), and crystal structure of some compounds was determined by X-ray crystallography. The in vitro biological screening effects of the synthesized compounds were tested against different microbial kinds. The results revealed that all compounds were biologically active. 相似文献
7.
Anil Kumar Gunthanakkala Madhu Sekhar Mangali Padmavathi Venkatapuram Padmaja Adivireddy 《Journal of heterocyclic chemistry》2020,57(12):4164-4174
A new class of bis(arylsulfonylmethylazolyl)pyridines and bis(arylaminosulfonylmethyl-azolyl)pyridines were synthesized from the synthetic intermediates methyl arylsulfonylacetic acid hydrazide and methyl arylaminosulfonylacetic acid hydrazide adopting a green methodology-ultrasonication. All the synthesized compounds were resulted in higher yield and in shorter reaction times. The spectral parameters such as IR, 1H NMR, 13C NMR, mass and microanalyzes were used to determine the structures of all the synthesized compounds and were assayed for antioxidant activity. The bis(arylaminosulfonylmethylazolyl)pyridines showed higher radical scavenging activity than the bis(arylsulfonylmethylazolyl)pyridines. Besides, unsubstituted, and methyl substituted compounds exhibited greater activity. Among all the tested compounds 8b and 11b were identified as potential antioxidants. 相似文献
8.
Wan Sharifatun Handayani Wan Zullkiplee Ainaa Nadiah Abd Halim Maya Asyikin Mohd Ariff Hasnain Hussain 《Phosphorus, sulfur, and silicon and the related elements》2013,188(6):832-838
AbstractA series of symmetrical 1,3-bis thiourea 1a–e and 1,4-bis thiourea derivatives 2a–e have been successfully synthesized from the reactions of amines with 3-acetylbenzoyl isothiocyanate and 4-acetylbenzoyl isothiocyanate, respectively. All the synthesized compounds were characterized by FT-IR spectroscopy and 1H and 13C NMR spectroscopy. The compounds were screened for their antibacterial activity by turbidimetric method using gram-negative bacteria (E. coli ATCC 8739) using turbidimetric method. The newly synthesized bis-thiourea derivatives bearing aryl side chains showed good antibacterial activity against E. coli. The effect of the molecular structure of the synthesized compounds on the antibacterial activity is discussed. 相似文献
9.
《Journal of heterocyclic chemistry》2017,54(2):1042-1047
A novel series of 2,5‐disubstituted‐1,3,4‐oxadiazoles decorated with two biodynamic moieties pyridine and 1,2,3‐triazole have been successfully synthesized in good yields under mild reaction conditions. The synthesized compounds are valuable for biological activity exploration since three biodynamic moieties are covalently linked together in a single molecular framework. All the synthesized compounds were fully characterized by their detailed spectral studies IR, 1HNMR, 13C NMR and Mass. 相似文献
10.
Shridhar Malladi Arun M. Isloor Shrikrishna Isloor D.S. Akhila Hoong-Kun Fun 《Arabian Journal of Chemistry》2013,6(3):335-340
In the present study a series of new Schiff bases were synthesized. All the synthesized compounds were characterized by IR, 1H NMR, mass spectral and elemental analyses. Newly synthesized compounds were screened for their antibacterial (Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa) activity. The results revealed that, compounds 3f and 3c have exhibited significant biological activity against the tested microorganisms. 相似文献
11.
Subhashini Naikal James Prameela Lavanya Jilla Sowmya Vanguru 《Journal of heterocyclic chemistry》2020,57(1):308-316
A new series of benzosuberone-piperazine hybrids 6a to j were designed and synthesized efficiently in good yields and their structures were confirmed by 1H NMR, 13C NMR, ESI-MS and HRMS. The newly synthesized compounds were evaluated for their in vitro antimicrobial activity against Gram positive, Gram negative bacterial strains and a fungal strain. Among the synthesized compounds, compounds 6c , 6d , 6e , 6f , 6g and 6h exhibited potent antibacterial activity with MIC value of 1.9 μg/mL against Gram positive and Gram negative organisms. 相似文献
12.
In the present study, a series of thiodihydropyrimidine derivatives were synthesized from different substituted aromatic aldehydes, ethyl acetoacetate, and urea/thiourea using a bimetallic TUD-1 catalyst. The structures of all the synthesized compounds were characterized by melting point determination, thin layer chromatography (TLC), infrared (IR), 1HNMR, and 13C-NMR values. All the synthesized compounds were screened for their antimicrobial activities against two gram positive bacteria, two-gram negative bacteria, and two fungal strains. 相似文献
13.
E. H. Mamedbeyli I. A. Jafarov G. M. Talybov M. A. Mirzoeva K. O. Iskenderova A. N. Hajizade 《Russian Journal of General Chemistry》2017,87(4):713-716
New aminomethoxy derivatives of 1-(butylsulfanyl)pentane have been synthesized. The structure of the synthesized compounds was studied by elemental analysis, IR and 1Н NMR spectroscopy, and mass spectrometry. Some specimens of the synthesized compounds were tested as antimicrobial additives to lubricant oil, and as aseptic compounds against bacteria and fungi. 相似文献
14.
Venkata Sreenivasa Rao Chunduru 《合成通讯》2013,43(10):1454-1460
An expeditious, one-pot reaction has been described for the preparation of 1,3,4-thiadiazin-5-yl-chromen-2-one derivatives. These compounds were synthesized by the reaction of 3-(2-bromoacetyl)coumarin with thiocarbohydrazide and various carbonyl compounds. The newly synthesized compounds were characterized by infrared, 1H NMR, and mass spectra. 相似文献
15.
Emil Tashev Viktoria Lachkova Helmut Keck Stoycho Shenkov Wolfgang Kläui Sabi Varbanov 《Phosphorus, sulfur, and silicon and the related elements》2013,188(9):1757-1767
A series of thirteen new carbamoyl and thiocarbamoyl derivatives of N-benzyl-aminomethyl-dimethyl-phosphine oxide have been synthesized and characterized. The compounds were prepared via interaction of N-benzyl-aminomethyl-dimethyl-phosphine oxide with the corresponding isocyanates or isothiocyanates. The composition of the synthesized novel compounds was proved by elemental analysis for nitrogen and the structures were confirmed by IR,1H-, 31P-31P{1H} NMR spectroscopy and by mass spectrometry. 相似文献
16.
《Arabian Journal of Chemistry》2020,13(12):8638-8649
A series of 6-aryl substituted pyrimidine azodyes were synthesized by coupling of phenyl pyrimidine 2-amine with different aromatic amines. The synthetic compounds were screened for their in-vitro antioxidant and anti-inflammatory activities. The characterization of the synthesized compounds was carried out by IR, 1H NMR, 13C NMR and Mass spectrophotometry. Computational study of designed compounds was done by OCHEM, Molinspiration cheminformatics, Datawarrior, and Swiss ADME. DPPH assay was used to determine the antioxidant activity and heat hemolysis method for anti-inflammatory activity. 相似文献
17.
Hany M. M. Dalloul Khaled A. El-Nwairy Ali Z. Shorafa Ahmed S. Abu Samaha 《Phosphorus, sulfur, and silicon and the related elements》2018,193(5):288-293
A new series of novel functionalized 1,3,4-thiadiazin-5-ones and 1,3,4-thiadi-azepin-5-ones bearing sulfonamide moieties were synthesized via 1,3-dipolar cyclocondensation reaction of nitrilimines with α-mercaptoesters and mercaptosuccinic acid respectively. The structures of the prepared compounds were confirmed by spectral methods (IR, 1H-NMR, 13C-NMR and MS spectroscopy) and elemental analysis. The newly synthesized compounds were screened for their in vitro antimicrobial activity. Some of titled compounds exhibited significant antimicrobial activity on several strains of microbes. 相似文献
18.
Min-Da Shau Wei-Kuo Chin 《Journal of polymer science. Part A, Polymer chemistry》1993,31(7):1653-1658
A new type of imide–epoxy resin in which imide compounds were grafted on the main chain of the epoxy was synthesized. The imide compounds used were mono (aminophthalimide)s. The structures of imide monomers and imide–epoxy polymers were confirmed by spectra characterizations of IR, 1H-, and 13C-NMR. The thermal resistances and solubilities of synthesized imide–epoxy were also studied. © 1993 John Wiley & Sons, Inc. 相似文献
19.
Preparation,structure elucidation,and antioxidant activity of new bis(thiosemicarbazone) derivatives
Hasan YAKAN 《Turkish Journal of Chemistry》2020,44(4):1085
Schiff-base–bearing new bis(thiosemicarbazone) derivatives were prepared from terephthalaldehyde and various thiosemicarbazides. FT–IR, 1H NMR, 13C NMR, and UV–Vis spectroscopic methods and elemental analysis were used to elucidate the identification of the synthesized molecules. The in vitro antioxidant activity of the synthesized compounds was analysed with the 1,1-diphenyl-2-picryl hydrazyl free-radical–trapping process. The synthesized compounds exhibited lower antioxidant activity than the standard ascorbic acid. IC50 values of the synthesized molecules measured from 3.81 ± 0.01 to 29.05 ± 0.11 μM. Among the synthesized compounds, compound 3 had the best antioxidant activity. Moreover, this study explained the structure–activity relationship of the synthesized molecules with different substituents in radical trapping reactions. 相似文献
20.
Islam H. El Azab Mohamed E. Khalifa Adil A. Gobouri Tariq A. Altalhi 《Journal of heterocyclic chemistry》2019,56(4):1352-1361
Considering pteridine as a worthy structure for improving probes of magnificent therapeutic potentials, some new pteridine conjugates were synthesized by aminomethylation of benzopteridinethione with a variety of primary aromatic amines and formaldehyde solution (37%) through the Mannich reaction. The proposed mechanism of formation of the synthesized compounds was discussed, and the structure of the newly synthesized compounds was elucidated on the basis of their IR, 1H NMR, 13C NMR, mass spectral, and elemental analyses. Furthermore, some selected compounds were evaluated in vitro for their antimicrobial activities; the preliminary data stated that the majority of the tested compounds exhibited significant antimicrobial activity. Analogues 22 , 23 , 20 , 19 , 24 , and 15 were found to be the most potent against all the tested microorganisms. 相似文献