共查询到19条相似文献,搜索用时 85 毫秒
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《广东微量元素科学》2015,(11)
抗菌涂料是涂料发展研究的重要方向之一。抗菌涂料是指在涂料中加入抗菌剂,使涂料具有抗菌性能,当用于室内涂装时可以有效降低居室、家具以及电器等表面的细菌密度。常用的抗菌剂包括有机抗菌剂、无机抗菌剂和天然抗菌剂3种。该文对抗菌涂料常用的3种类型抗菌剂进行介绍,并对其抗菌机理进行概述。 相似文献
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微生物感染已经成为人类健康的第一杀手,同时给人们带来了巨大的经济损失,特别是在公共医疗卫生、食品安全等方面。使用抗菌剂是防治微生物滋生和繁殖的有效手段。与无机抗菌剂、有机抗菌剂和天然抗菌剂相比,抗菌聚合物因其有效官能团密度高、低毒、长效等优点,正成为目前科研的热点。本文介绍了抗菌聚合物的制备方法、分类和抗菌机理,并基于近五年来的文献资料,综述了在医疗领域、食品领域和纺织领域中抗菌聚合物的研究进展。 相似文献
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一种新型胍盐抗菌剂的制备及其性能研究 总被引:1,自引:0,他引:1
采用盐酸胍盐、六亚甲基二胺、二乙基三胺和环氧氯丙烷为原料合成了一种新型的胍盐抗菌剂,使其同时起到抗菌和提高纸页湿强度的作用。用二维核磁共振谱(HH-COSY)对胍盐抗菌剂的结构进行了表征,同时研究了胍盐抗菌剂对大肠杆菌的最低抑菌浓度和对纸张的增湿强效果。通过UV吸收法和激光共聚焦显微镜对胍盐抗菌剂的抗菌机理进行了进一步的研究,结果表明,胍盐抗菌剂主要是通过先破坏细菌的细胞膜,然后引起细胞内的物质流出细胞,从而抑制细菌的生长繁殖。 相似文献
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Quantitative evaluation of antibacterial activities of nanoparticles (ZnO,TiO2, ZnO/TiO2, SnO2, CuO,ZrO2, and AgNO3) incorporated into polyvinyl butyral nanofibers
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Novel hybrid polyvinyl butyral nanofibers have been developed for antimicrobial applications. The nanofiber mats were obtained from a needleless rod electrospinning system. The novel inorganic antibacterial agents were incorporated into the nanofibers, and their antibacterial activity was compared. The obtained nanoparticle/nanofiber hybrid mats have a good surface morphology. The results indicated that the CuO, ZnO, ZnO/TiO2, and AgNO3 nanoparticle‐incorporated nanofiber layers have excellent antibacterial activity against to Escherichia coli compared with TiO2, SnO2, and ZrO2 ones. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献
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Viktoriia Korniienko Yevheniia Husak Julia Radwan-Pragowska Viktoriia Holubnycha Yevhen Samokhin Anna Yanovska Julia Varava Kateryna Diedkova ukasz Janus Maksym Pogorielov 《Molecules (Basel, Switzerland)》2022,27(10)
Chitosan, a natural biopolymer, is an ideal candidate to prepare biomaterials capable of preventing microbial infections due to its antibacterial properties. Electrospinning is a versatile method ideally suited to process biopolymers with minimal impact on their physicochemical properties. However, fabrication parameters and post-processing routine can affect biological activity and, therefore, must be well adjusted. In this study, nanofibrous membranes were prepared using trifluoroacetic acid and dichloromethane and evaluated for physiochemical and antimicrobial properties. The use of such biomaterials as potential antibacterial agents was extensively studied in vitro using Staphylococcus aureus and Escherichia coli as test organisms. The antibacterial assay showed inhibition of bacterial growth and eradication of the planktonic cells of both E. coli and S. aureus in the liquid medium for up to 6 hrs. The quantitative assay showed a significant reduction in bacteria cell viability by nanofibers depending on the method of fabrication. The antibacterial properties of these biomaterials can be attributed to the structural modifications provided by co-solvent formulation and application of post-treatment procedure. Consequently, the proposed antimicrobial surface modification method is a promising technique to prepare biomaterials designed to induce antimicrobial resistance via antiadhesive capability and the biocide-releasing mechanism. 相似文献
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In this research, the possibility of producing and processing nanocomposite polypropylene filament yarns with permanent antimicrobial efficiency has been assessed by comparing two different methods. Therefore two approaches were used to mix various blending contents of antimicrobial agents based on silver/TiO2 nano particles with PP: 1) mixing of PP powder and inorganic nanocomposite powder as an antibacterial agent with the appropriate concentration in a twin screw extruder, preparing modified granules and feeding them to the melt spinning machine, 2) producing masterbatch by a twin screw extruder and blending it with PP in the melt spinning process. In both methods, pure PP and all other combined samples had an acceptable spinnability at the spinning temperature of 240 °C and take-up speed of 2000 m/min. After producing as-spun filament yarns by a pilot plant melt spinning machine, samples were drawn, textured and finally weft knitted. Physical and structural properties of as-spun and drawn yarns with constant and variable draw ratios were investigated and compared. Moreover, the DSC, SEM and FTIR techniques have been used for samples characterization. Finally antibacterial efficiency of knitted samples was evaluated. The experimental results indicated that the maximum crystallinity reduction of modified as-spun yarns reached 5%. But by applying method 2 (masterbatch), crystallinity of modified as-spun yarns remained unchanged compared to pure yarn. However, drawing procedure has compensated this difference. By applying the second method, the drawing generally improved the increase of tenacity and modulus of modified fibers, whereas in method 1 the opposite effect was noticed in the case of constant draw ratio. Although the biostatic efficiency of nanocomposite fibers was excellent in both methods, modified fabrics obtained from method 1 showed higher bioactivity. 相似文献
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Chongyi Zhu Dan Chang Xiao Wang Danxia Chai Lili Chen Alideertu Dong Ge Gao 《先进技术聚合物》2019,30(6):1386-1393
As a significant role in subcategory of halogen antibacterial field, amphiphilic N‐halamine polymers show a promise as potential antimicrobials having a broad spectrum of microorganisms, long‐term stability, and renewal of their antibacterial properties. By controlling the process parameters, electrospinning has been well recognized as a versatile and effective method being capable of making fibers and could be easily engineered with desired pore size and porosity to enhance the antimicrobial properties. The amphiphilic N‐halamine P (ADMH‐MMA‐HEMA) terpolymer fibers showed efficient antimicrobial properties against both Gram‐positive and Gram‐negative bacteria within brief contact time. The result meant that the polymer fibers of macromolecular architecture with control of structural parameters such as hydrophobicity/hydrophilicity balance achievement improved antimicrobial activities via electrospinning technique. In vitro cytotoxicity study demonstrated that the polymer was biocompatible. As a result, the integration of amphiphilic antibacterial materials and the electrospinning technique provided us a feasible method to fabricate biocompatible antimicrobial products easily with low manufacturing cost and would be applied in many promising application areas. 相似文献
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B. Ashok Krittirash Yorseng N. Rajini N. Hariram Suchart Siengchin 《International Journal of Polymer Analysis and Characterization》2018,23(6):509-516
Ligno-cellulosic fibers have a great market and propose higher value addition and options to develop various products but they do not have inherent antimicrobial properties. In this study, a simple hydrothermal method was applied to build up antimicrobial properties to natural fibers by in situ-generating silver nanoparticles (AgNPs) in them. Herein, the ligno-cellulosic Thespesia lampas natural fibers were selected to develop antimicrobial activity using silver nitrate (AgNO3) solution by hydrothermal method. The modified fibers were characterized by SEM, FTIR, XRD, TGA, and antibacterial activity tests. The modified fibers had spherical AgNPs with an average size of 95?nm. The thermal stability of the modified fibers was higher than that of the unmodified fibers. The modified fibers exhibited good antibacterial activity against both the Gram negative and Gram positive bacteria. These modified fibers can be considered as fillers in polymer matrices to make antibacterial composites. 相似文献
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Nur Farisya Shamsudin Qamar Uddin Ahmed Syed Mahmood Syed Adnan Ali Shah Alfi Khatib Sayeed Mukhtar Meshari A. Alsharif Humaira Parveen Zainul Amiruddin Zakaria 《Molecules (Basel, Switzerland)》2022,27(4)
According to the latest report released by the World Health Organization, bacterial resistance to well-known and widely available antibacterial drugs has become a significant and severe global health concern and a grim challenge to tackle in order to cure infections associated with multidrug-resistant pathogenic microorganisms efficiently. Consequently, various strategies have been orchestrated to cure the severe complications related to multidrug-resistant bacteria effectively. Some approaches involved the retardation of biofilm formation and multidrug-resistance pumps in bacteria as well as the discovery of new antimicrobial agents demonstrating different mechanisms of action. In this regard, natural products namely alkaloids, terpenoids, steroids, anthraquinone, flavonoids, saponins, tannins, etc., have been suggested to tackle the multidrug-resistant bacterial strains owing to their versatile pharmacological effects. Amongst these, flavonoids, also known as polyphenolic compounds, have been widely evaluated for their antibacterial property due to their tendency to retard the growth of a wide range of pathogenic microorganisms, including multidrug-resistant bacteria. The hydroxylation of C5, C7, C3′, and C4′; and geranylation or prenylation at C6 have been extensively studied to increase bacterial inhibition of flavonoids. On the other hand, methoxylation at C3′ and C5 has been reported to decrease flavonoids’ antibacterial action. Hence, the latest information on the antibacterial activity of flavonoids is summarized in this review, with particular attention to the structure–activity relationship of this broad class of natural compounds to discover safe and potent antibacterial agents as natural products. 相似文献
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稀土、钼酸、糠醛缩水杨酰肼三元配合物的合成、 表征及生物活性的研究 总被引:4,自引:0,他引:4
通过回流冷凝法和低温固相法制备了8种稀土、钼酸、糠醛缩水杨酰肼三元配合物, 并通过元素分析, 摩尔电导, IR, UV-vis, TG-DTA, TC-ICP, XRD, XPS对其结构和化学组成进行表征, 确定其化学组成为Re(HL)MoO4Cl8226;6H2O (HL: 糠醛缩水杨酰肼), 通过抑菌实验表明所制备的三元化合物对大肠杆菌和金黄色葡萄球菌具有中等抑制作用, 属于广谱抗菌剂; 通过MTT比色法对配合物使癌细胞凋亡能力做了初步研究, 结果表明, 三元配合物的IC50在10~100 ng/mL之间, 对癌细胞具有较强的抑制杀伤作用, 具有潜在的药物应用价值. 相似文献
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Manjunath Giridhar Halehatty S. Bhojya Naik Chatnalli N. Sudhamani Mustur C. Prabakara Rajappa Kenchappa Nagaraju Venugopal Sameer Patil 《中国化学会会志》2020,67(2):316-323
ZnO nanoparticles were successfully synthesized using a microwave method, whose surface was modified with {4-[(E)-2-(furan-2-yl)ethenyl]pyridin-1-ium-1-yl}acetate as a capping agent (1 and 3%). Their structural properties were investigated using FTIR, XRD, SEM, EDS, and UV–visible spectroscopy. XRD confirmed the Wurtzite structure for all compounds, a size of 30.6 nm for uncapped and 22.9 nm for 3% dye-capped nanoparticles were calculated from Scherer's equation. Hexagonal wurtzite shape of nanoparticles can be clearly seen in the SEM images. The DFT calculations were carried out using quantum espresso. These dye-capped ZnO nanoparticles were proved to be potential antibacterial agents, the minimum concentrations of dye-capped ZnO nanoparticles that inhibit the growth of bacteria are 1.5 mg/mL for Escherichia coli and 0.78 mg/mL for Bacillus subtilis, which are much lower than those of uncapped ZnO. The bioactivity data suggest these organic–inorganic hybrid nanoparticles emerged as a new class of antibacterial agents. 相似文献
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Prof. Miguel A. Sierra Prof. Luis Casarrubios Dr. María C. de la Torre 《Chemistry (Weinheim an der Bergstrasse, Germany)》2019,25(30):7232-7242
Overuse and misuse of antibacterial drugs has resulted in bacteria resistance and in an increase in mortality rates due to bacterial infections. Therefore, there is an imperative necessity of new antibacterial drugs. Bio-organometallic derivatives of antibacterial agents offer an opportunity to discover new active antibacterial drugs. These compounds are well-characterized products and, in several examples, their antibacterial activities have been studied. Both inhibition of the antibacterial activity and strong increase in the antibiotic activity of the parent drug have been found. The synthesis of the main classes of bio-organometallic derivatives of these drugs, as well as examples of the use of structure–activity relation (SAR) studies to increase the activity and to understand the mode of action of bio-organometallic antimicrobial peptides (BOAMPs) and platensimicyn bio-organometallic mimics is presented in this article. 相似文献