Global stability of solutions to a free boundary problem of ductal carcinoma in situ

In the paper we present some remarks on the global stability of steady state solutions to a free boundary model studied by Xu (2004) and also prove some new results of global stability of steady state solutions to the model.     

Multiplicity results for the unstirred chemostat model with general response functions

We investigate the multiplicity of positive steady state solutions to the unstirred chemostat model with general response functions. It turns out that all positive steady state solutions to this model lie on a single smooth solution curve, whose properties determine the multiplicity of positive steady state solutions. The key point of our analysis is to study the “turning points” on this positive steady state solution curve, and to prove that any nontrivial solution to the associated linearized problem is one of sign by constructing a suitable test function. The main tools used here include bifurcation theory, monotone method, mountain passing lemma and Sturm comparison theorem.     

Analysis of stability and Hopf bifurcation for HIV-1 dynamics with PI and three intracellular delays

Mathematical model for the effects of protease inhibitor on the dynamics of HIV-1 infection model with three delays is proposed and analyzed. Some analytical results on the global stability of viral free steady state and infected steady state are obtained. The stability/instability of the positive steady state and associated Hopf bifurcation are investigated by analyzing the characteristic equations.     

GLOBAL STABILITY IN A VIRAL INFECTION MODEL

This paper investigates the global stability of a viral infection model with lytic immune response. If the basic reproductive ratio of the virus is less than or equal to one, by the LaSalle's invariance principle, the disease-free steady state is globally asymptotically stable. If the basic reproductive ratio of the virus is greater than one but less than or equal to a constant, which is defined by the parameters of the model, then the immune-exhausted steady state is globally asymptotically stable. The endemic steady state is globally asymptotically stable if the inverse is valid.     

Stability of a stochastic SEIS model with saturation incidence and latent period

In this paper, a stochastic SEIS epidemic model with a saturation incidence rate and a time delay describing the latent period of the disease is investigated. The model inherits the endemic steady state from its corresponding deterministic counterpart. We first show the existence and uniqueness of the global positive solution of the model. Then, by constructing Lyapunov functionals, we derive sufficient conditions ensuring the stochastic stability of the endemic steady state. Numerical simulations are carried out to confirm our analytical results. Furthermore, our simulation results shows that the existence of noise and delay may cause the endemic steady state to be unstable.     

Travelling waves in an infectious disease model with a fixed latent period and a spatio–temporal delay

This paper is concerned with the existence of travelling waves to an infectious disease model with a fixed latent period and a spatio–temporal delay. By analyzing the corresponding characteristic equations, the local stability of a disease-free steady state and an endemic steady state to this model is discussed. By constructing a pair of upper–lower solutions, we use the cross iteration method and the Schauder’s fixed point theorem to prove the existence of a travelling wave solution connecting the disease-free steady state and the endemic steady state. Numerical simulations are carried out to illustrate the main results.     

A note on a diffusive predator-prey model and its steady-state system

In this note, a diffusive predator-prey model subject to the homogeneous Neumann bound- ary condition is investigated and some qualitative analysis of solutions to this reaction-diffusion system and its corresponding steady-state problem is presented. In particular, by use of a Lyapunov function, the global stability of the constant positive steady state is discussed. For the associated steady state problem, a priori estimates for positive steady states are derived and some non-existence results for non-constant positive steady states are also established when one of the diffusion rates is large enough. Consequently, our results extend and complement the existing ones on this model.     

Travelling waves of a predator–prey model with a spatiotemporal delay

This paper is concerned with the existence of traveling waves to a predator–prey model with a spatiotemporal delay. By analyzing the corresponding characteristic equations, the local stability of a positive steady state and each of boundary steady states are established, and the existence of Hopf bifurcation at the positive steady state is also discussed. By constructing a pair of upper–lower solutions and by using the cross‐iteration method as well as the Schauder's fixed‐point theorem, the existence of a traveling wave solution connecting the semi‐trivial steady state and the positive steady state is proved. Numerical simulations are carried out to illustrate the main theoretical results. Copyright © 2013 John Wiley & Sons, Ltd.     

Finding all steady state solutions of chemical kinetic models

Ordinary differential equations are used frequently by theoreticians to model kinetic process in chemistry and biology. These systems can have stable and unstable steady states and oscillations. This paper presents an algorithm to find all steady state solutions to a restricted class of ODE models, for which the right-hand sides are linear combinations of rational functions of variables and parameters. The algorithm converts the steady state equations into a system of polynomial equations and uses a globally convergent homotopy method to find all the roots of the system of polynomials. All steady state solutions of the original ODEs are guaranteed to be present as roots of the polynomial equations. The conversion may generate some spurious roots that do not correspond to steady state solutions. The stability properties of the steady states are not revealed. This paper explains the algorithms used and gives results for a cell cycle modeling problem.     

Multiple Equilibria and Thresholds Due to Relative Investment Costs

A dynamic model of the firm is studied in which investment costs depend on the magnitude of the investment relative to the stock of capital goods. It is shown that in general nonunique steady states can exist which can be stable or unstable. It is possible that unstable steady states occur in the concave domain of the Hamiltonian. For a particular specification, a scenario occurs with two stable steady states and one unstable steady state. The two stable steady states are long run equilibria; which one of them is reached in the long run depends on the initial state. In case the Hamiltonian is locally concave around the unstable steady state, this steady state is the threshold that separates the domain of initial conditions that each of the stable steady states attracts. The unstable steady state is a node and investment is a continuous function of the capital stock. If the unstable steady state lies in the nonconcave domain of the Hamiltonian, this steady state can either be a node or a focus. Furthermore, continuity can (but need not) be retained similarly to the concave case, a fact which has been entirely overlooked in the literature.     

Stability analysis of diffusive predator-prey model with modified Leslie-Gower and Holling-type III schemes

The stability of a diffusive predator-prey model with modified Leslie-Gower and Holling-type III schemes is investigated. A threshold property of the local stability is obtained for a boundary steady state, and sufficient conditions of local stability and un-stability for the positive steady state are also obtained. Furthermore, the global asymptotic stability of these two steady states are discussed. Our results reveal the dynamics of this model system.     

Stability Analysis of Diffusive Predator-Prey Model with Modified Leslie-Gower and Holling-Type II Schemes

The stability of a diffusive predator-prey model with modified Leslie-Gower and Holling-type II schemes is investigated. A threshold property of the local stability is obtained for a boundary steady state, and sufficient conditions of local stability and un-stability for the positive steady state are also obtained. Furthermore, the global asymptotic stability of these two steady states are discussed. Our results reveal the dynamics of this model system.     

A microbial continuous culture system with diffusion and diversified growth

A reaction-diffusion model is presented to describe the microbial continuous culture with diversified growth. The existence of nonnegative solutions and attractors for the system is obtained, the stability of steady states and the steady state bifurcation are studied under three growth conditions. In the case of no growth inhibition or only product inhibition, the system admits one positive constant steady state which is stable; in the case of growth inhibition only by substrate, the system can have two positive constant steady states, explicit conditions of the stability and the steady state bifurcation are also determined. In addition, numerical simulations are given to exhibit the theoretical results.     

The Steady-State Behaviour of a Manpower Planning Model in Which Class Corresponds to Length of Service

We consider a discrete time Markov population model in which class corresponds to length of service. For this particular system it is shown that the steady state distributions of class sizes are independently Poisson. The model is applied to eight firms for which the steady state tenure distribution is evaluated.     

Steady state analysis of a nonlinear renewal equation

In the analysis of a nonlinear renewal equation it is natural to anticipate the existence of nonzero steady states and deal with the question of their stability. Sufficient conditions for existence and uniqueness for these steady states are given. The study of the linearized version of the renewal equation around the steady state helps to a great extent to have insight into some complicated dynamics of the full problem. At this stage the first eigenvalue of the steady state plays a vital role. The characteristic equation, a functional equation whose roots are the eigenvalues, is derived. We give various structures showing that the steady state may be stable or unstable (though the fertility rate is decreasing with competition). A similar study is carried out on a nonlinear model motivated by neuroscience in which the total population is conserved.     

THE QUALITATIVE CONTENT OF RENEWABLE RESOURCE MODELS

This paper analyzes the extent to which standard dynamic renewable resource models possess refutable implications. Both the steady state comparative static and local comparative dynamic properties of the standard model are studied. A unified framework is developed which enables one to analyze the qualitative properties of any standard renewable resource model. This is achieved by explicitly linking the local stability, steady state comparative static, and local comparative dynamic properties of the model.     

机会维修策略下的系统可用度分析

机会维修是针对多部件系统提出的一类新的维修策略,主要解决部件间存在经济相关性的问题.利用更新过程理论建立了机会维修策略下的系统模型,并给出了系统瞬态和稳态可用度的求解方法.通过分析比较可知,利用更新过程稳态下的某些特性,可以不必求解更新方程而比较简便地求解系统稳态可用度.     

具有接种和非局部扩散的流行病模型的行波解（英文）

An epidemic model with vaccination and nonlocal diffusion is proposed, and the existence of traveling wave solutions of this model is studied. By the cross-iteration scheme companied with a pair of upper and lower solutions and Schauder’s fixed point theorem,sufficient conditions are obtained for the existence of a traveling wave solution connecting the disease-free steady state and the endemic steady state.     

有界域上三维非等熵半导体方程解的渐近性(英文)

本文讨论了一类三维非等熵半导体方程. 利用能量估计法, 证明了热平衡稳态解的存在唯一性.然后, 得到了Cauchy-Neumann问题光滑解的整体存在性以及当t→ +∞这种光滑解以指数速度收敛到稳定解, 改进了文献[12]的结果.