Modification of DNA by photoactivable aryl azides

Features of the interaction with DNA of photoactivable aryl azides having various substituents in the aromatic ring have been studied. The nature of the interaction with DNA and the degree of its modification depend substantially on the nature of these substituents. The results obtained can be used for obtaining DNA probes bearing various marker groups.Institute of Medical Genetics, Academy of Medical Sciences of USSR, Moscow. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 259–263, March–April, 1989.     

Synthesis of model dimers of lignin from (1-hydroxyalkyl)phenols

It has been shown that model (1-hydroxyalkyl)phenols of lignin condense in an acid medium with heating to form dimers of the indan and Ar-C₃-Ar series, depending on the substituents in the aromatic ring.Institute of Chemistry of Plant Substances, Uzbekistan Academy of Sciences, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 564–567, September–October, 1992.     

Reaction of aryldiazonium salts with acetone oxime

The reaction of aryl diazonium salts containing electron-withdrawing substituents in the aromatic ring with acetone oxime leads to the formation of nitrogen-containing products instead of the expected functional derivatives of 1-alkyl-3-aryltriazene 1-oxides. The structure of these products is a function of the number and chemical nature of the substituents in the diazo component.N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, 117913 Moscow. Translated from Izvestiya Akademii Nauk, Seriya Khimicheskaya, No. 8, pp. 1911–1913, August, 1992.     

PMR spectra of natural stilbene compounds

Summary 1. The PMR spectra of 13 natural stilbenes have been studied.2. The dominating role of -electron interaction of the fragments of the stilbene molecule in the screening of the aromatic and olefinic protons has been shown. A series of increments presenting interest for determining the structure of stilbene compounds is proposed.3. It has been established that the nature and nature and number of the substituents in the aglycone part of the molecule have no influence on the screening of the anomeric proton of glycosidated stilbenes, but it does depend on the position of attachment of the carbohydrate fragment.A. A. Zhdanov Irkutsk State University. Irkutsk Institute of Organic Chemistry, Siberian Branch of the Academy of Sciences of the USSR. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 3–10, January–February, 1976.     

Field-desorption mass spectra of flavonoid acylglycosides. II. Natural cinnamoyl and benzoyl derivatives

The field-desorption mass spectra of 14 flavonoid glycosides esterified with p-coumaric, ferulic, caffeic, p-hydroxybenzoic, and gallic acids have been studied. For all the compounds the molecular ions and the ions of the aglycone (A) were obtained as the main peaks. The spectra also contained a number of other fragmentary ions, including the ion of the acylated anhydrosugar. For flavonol glycosides in which the carbohydrate is esterified by cinnamic acids, the (A + Ac), and for the diacylglycosides the (A + 2 Ac), ions are diagnostic. The formation of these strong ions corresponding in mass to the molecules of the mono- and diacylated aglycone permits the assumption of the existence of acyl migration in the breakdown of the initial molecular ion.All-Union Scientific-Research Institute of Medicinal Plants, Moscow. L. Ya. Karpov Scientific-Research Institute of Physical Chemistry. Irkutsk Institute of Organic Chemistry, Siberian Branch, Academy of Sciences of the USSR. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 582–589, September–October, 1984.     

Recyclization of substituted furoxans into 1,2,3-triazol-1-oxide derivatives

The effect of the position and nature of substituents on the recyclization of substituted furoxans has been established.N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences (RAN), Moscow 117913, Russia Institute of Chemical Physics in Chernogolovka, Russian Academy of Sciences (RAN), Chernogolovka 142432, Russia. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 202–209, February, 1999.     

Transformation of aromatic compounds under the action of the basidiomycetesPhanerochaete sanguinea andCoriolus villosus

The pathways of the transformation of some aromatic compounds by rhe basidiomycetesPhanerochaete sanguinea andCoriolus villosus have been studied. It has been shown that the degradation of these compounds has an oxidative nature and depends on the type of substituents in the benzene ring and the propane chain. A difference has been found in the mechanisms of the reactions of the two fungi that is a consequence of the different compositions of their enzyme complexes.Wood Chemistry Division, Institute of Organic Chemistry, Siberian Division of the Russian Academy of Sciences, Irkutsk. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 808–819, November–December, 1994.     

4',4”- and 4',5”-di-sec-butyl-2,3:11,12-dibenzo-18-crown-6 — An ionophore for magnesium in natural and model systems

The ionophoric properties of the di-sec-butyl derivatives of dibenzo-18-crown-6 have been studied in natural and model membranes. It has been shown that the di-sec-butyl substituents in the benzene rings of dibenzo-18-crown-6 impart to the cyclopolyether the properties of an ionophore for magnesium. The Mg²⁺/Ca²⁺ selectivity of the cyclopolyether investigated was 4.8 according to results obtained on artifical membranes and mitochondria.Institute of Biochemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Institute of Bioorganic Chemistry, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 234–239, March–April, 1981.     

Mass spectra of the alkaloids ofDipthychocarpus strictus

The mass spectra of diptocarpaine, diptocarpamine, diptocarpiline, and diptocarpidine, isolated fromDipthychocarpus strictus, have been studied. These compounds have proved to be derivatives of alkylureas, the substituents in them being mainly methylthio-n-hexyl and methylsulfinyl-n-hexyl radicals and the products of their chemical transformation. It has been established that mass-spectrometric fragmentation of these compounds takes place with the formation of heterocyclic ions.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 365–370, May–June, 1980.     

A mass spectrometric study of some triterpenes of the dammarane series

Summary 1. The mass spectra of tetracyclic triterpenes of the dammarane series with substituents at C-3, 6, and 12 and with side chains of various structures have been studied.2. The main direction of fragmentation is the formation of ions as the result of the decomposition of the side chain and of ring C, the second type of fragmentation being controlled by the structure of the side chain.Institute of Biologically Active Substances of the Far-Eastern Scientific Center of the Academy of Sciences of the USSR. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 286–294, May–June, 1971.     

Synthesis of 4-trifluoromethyl-7-hydroxycoumarin derivatives. Structure of 3-cyano-4-trifluoromethyl-7-acetoxycoumarin

A method was developed for the production of derivatives of 4-trifluoromethyl-7-hydroxycoumarin with electron-withdrawing groups (CN, CF₃CO) at position 3. The structure of 3-cyano-4-trifluoromethyl-7-acetoxycoumarin was proved by x-ray crystallographic investigation. The effect of the substituents on the geometry of the molecule is discussed.N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, 117913 Moscow. A. N. Nesmeyanov Institute of Heteroorganic Compounds, Russian Academy of Sciences, 117813 Moscow. Institute of Biochemistry, Academy of Sciences of Armenia, 375044 Erevan. Translated fromIzvestiya Akademii Nauk, Seriya Khimicheskaya, No. 6, pp. 1371–1375, June, 1992.     

Phytoecdysteroids ofSilene nutans. II. 22-Deoxyecdysterone and features of its mass spectrum

Using high-performance liquid chromatography, 22-deoxyecdysterone has been isolated from the butanolic fraction of the extractive substances from the epigeal part ofSilene nutans L. Characteristic features of the mass spectrum of 22-deoxyecdysterone due to the absence of an oxygen function at C-22 are discussed.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 62–66, January–February, 1985.     

Mass spectrum of glycosides of ecdysteroids and their peracetates

Features of the fragmentation of the carbohydrate chains of galactopyranosides of ecdysteroids (sileneosides A–D) and their peracetates under electron impact are discussed. The migration of Gal and AcGal residues from C-22 to C-20 has been detected. The secondary-ion mass spectra of the sileneosides using liquid matrices are considered.Institute of Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. All-Union Scientific-Research Institute of Agricultural Biotechnology, V. I. Lenin All-Union Academy of Agricultural Sciences, Moscow. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 226–231, March–April, 1991.     

Phytoecdysones ofAjuga turkestanica VI. 22-Acetylcyasterone

Summary The leaves ofAjuga turkestanica (Rg1.) Briq. have yielded a new ecdysone — 22-acetyl-cyasterone. The mass spectrum of this new ecdysone and the features of it due to the presence of the acetoxy group at C-22 have been discussed.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 215–219, March–April, 1978.     

13C NMR spectra of steroid glycosides. III. Acetates of pennogenin triosides

The¹³C NMR spectra of two pennogenin trioside acetates have been measured and an assignment has been made of the signals of the C atoms. The mutual influence of the aglycone and of the acetylated carbohydrate chains, and also of the acetylated monosaccharides composing the carbohydrate chains, have been determined.Pacific Ocean Institute of Bioorganic Chemistry, Far Eastern Scientific Center, Academy of Sciences of the USSR, Vladivostok. Translated from Pirodnykh Soedinenii, No. 4, pp. 463–465, July–August, 1983.     

1H and13C NMR spectra of 1,5-disubstituted 1,3,4-oxadiazoles

The¹H and¹³C NMR spectra of 2, 5-disubstituted 1,3,4-oxadiazoles with aliphatic, aromatic, and hetero-aromatic substituents have been described and interpreted. The electronic effect of the 1,3,4-oxadiazole group as a benzene ring substituent was evaluated using¹³C NMR spectroscopy.N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, 117913 Moscow. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 834–842, June, 1994. Original article submitted April 8, 1994.     

Crystal structure investigation of ternary molybdates Li3Ba2Ln3(MoO4)3 (Ln=Gd,Tm)

Institute of Inorganic Chemistry, Siberian Branch, Russian Academy of Sciences. Institute of Physics, Siberian Branch, Russian Academy of Sciences. Buryat Institute of Natural Sciences, Siberian Branch, Russian Academy of Sciences. Translated from Zhurnal Strukturnoi Khimii, Vol. 33, No. 3, pp. 126–130, May–June, 1992.     

Enzyme peroxidase in calluses of cotton plants of the speciesGossypium hirsutum andG. herbaceum

A comparative study has been made of the activity of the enzyme peroxidase and its isozyme spectrum from two species of cotton plant. It has been found that, as calluses grow, new isoforms of peroxidase are produced and the protein content increases.A. S. Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan, fax 627071. Institute of Genetics, Academy of Sciences of the Republic of Uzbekistan, fax 642230. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 90–92, January–February, 1994.