Alkaloids ofColchicum luteum

The paper gives a review of the alkaloids ofColchium luteum Baker from various growth sites. The structure of luteidine — one of the main alkaloids of the plant — has been established. In addition, two new alkaloids have been isolated from the plant and the structure of one of them has been established as collutine N-oxide.M. I Kalinin Turkmen Agricultural Institute, Ashkhabad, and V. I. Lenin Tashkent State University. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 810–815, November–December, 1985.     

Structure of alkaloid L-5 fromColchicum luteum

Conclusions FromColchicum luteum Baker collected in the gorge of the Sazan-Ata River in the Chimkent region have been isolated the known alkaloids colchamine, 3-desmethylcolchamine, 3-desmethyl--lumicolchicine, colchicine, 2-desmethylcolchicine, -lumicolchicine, N-desacetyl-N-formylcolchicine, and luteidine, and the new alkaloids L-5 and L-6. The first three bases have been obtained from this plant for the first time.Paper chromatography showed the presence of another three new alkaloids with R _f 0.38, 0.40, and 0.86. On the basis of UV, IR, and NMR spectroscopy and chemical reactions, the structure of 2-desmethylcolchiceine has been proposed for the alkaloid L-5.Khimiya Prirodnykh Soedinenii, Vol. 6, No. 1, pp. 82–88, 1970     

Alkaloids ofPetilium eduardi

Summary 1. Imperialine, imperialone, peimisine, and the new alkaloids edpetiline, eduardine, edpetilidine, and edpetilidinine have been isolated from the epigeal part ofP. eduardi.2. The hydrolysis of edpetiline has given D-glucose and imperialine.3. The structural formula of edpetiline has been established by the condensation of imperialine with tetraacetylbromoglucose.Khimiya Prirodnykh Soedinenii, Vol. 1, No. 6, pp. 384–392, 1965.     

Alkaloids ofHaplophyllum dubium

From the epigeal part ofHaplophyllum dubium we have isolated dubamine, -fagarine, skimmianine, graveoline, haplopine, the new alkaloid norgraveoline, and the steroid -sitosterol. This is the first time that -fagarine has been found in this plant. On the basis of the results of a study of spectral characteristics and also passage to the known alkaloid graveoline, it has been established that norgraveoline has the structure of 2-piperonyl-4-quinolone.Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 810–812, November–December, 1979.