基于激光尾波加速的涡轮叶片高能X射线CT

发展微焦点高能X射线源技术是实现高精度高能工业CT突破的关键,基于激光尾波加速驱动高能轫致辐射源开展了微焦点高能X射线源产生以及对涡轮叶片高能CT成像研究。利用一台20 TW钛蓝宝石超快超强激光器,通过电离注入的方式获得了（140±44）pC的高能电子束,并使用1.5 mm厚钨靶产生了累积源尺寸为25 μm的高能轫致辐射X射线。利用该微焦点高能X射线源,采用基于压缩感知的CT重建算法,在获取较少角度投影（31个角度）的情况下,获得了对涡轮叶片叶榫结构的CT重建。     

Laser optical feedback tomography

We describe a new method for imaging in three-dimensional turbid media, laser optical feedback tomography. This technique is based on the resonant sensitivity of a short-cavity laser to frequency-shifted optical feedback from ballistic photons retrodiffused from the medium. The advantage of the method is that the detector is the laser source itself, which provides optical amplification with self-aligned spatial and temporal coherent detection.     

Swept source optical coherence tomography based on non-uniform discrete fourier transform

A high-speed high-sensitivity swept source optical coherence tomography （SSOCT） system using a high speed swept laser source is developed. Non-uniform discrete fourier transform （NDFT） method is introduced in the SSOCT system for data processing. Frequency calibration method based on a Mach-Zender interferometer （MZI） and conventional data interpolation method is also adopted in the system for comparison. Optical coherence tomography （OCT） images from SSOCT based on the NDFT method, the MZI method, and the interpolation method are illustrated. The axial resolution of the SSOCT based on the NDFT method is comparable to that of the SSOCT system using MZI calibration method and conventional data interpolation method. The SSOCT system based on the NDFT method can achieve higher signal intensity than that of the system based on the MZI calibration method and conventional data interpolation method because of the better utilization of the power of source.     

生物医学领域中超连续激光光谱技术的研究进展

超连续谱激光指的是当泵浦激光穿过特殊光波导时,一系列的非线性效应引起入射激光束的光谱展宽,从而输出宽光谱激光束。随着超快激光和光子晶体光纤技术的发展,利用超短脉冲在光子晶体光纤中的传播链产生相干的且亮度高的超连续谱激光成为了一种理想的白光源。自从超连续谱激光源投入应用以来,其应用领域越来越广。尤其在生物医学的细胞、血液等样品分析当中,荧光光谱学、流式细胞仪、共焦显微、光学相干层析等技术都是强有力的分析工具,在采用这些先进技术的科学仪器中,超连续谱激光源成为了一种主要光学部件。首先对超连续谱激光源的国际研究进展作了详细介绍,然后对超连续激光光谱技术在显微成像、流式细胞仪、荧光寿命成像显微、荧光共振能量转移、光学相干层析、共焦显微生物医学分析等生物医学领域中的发展及应用作了综合阐述。对超连续激光光谱技术在非接触式血液制品鉴别的需求、方案及研究进展进行了重点论述,包括覆盖400～2 000 nm光谱范围的光纤化轻型超连续谱激光光源研究;采用超连续谱激光光谱方法探索不同物种血液的种属特征;根据大数据的血液样品光谱特征元数据库分析建立数学模型,利用数学模型实现对血液样品种属光谱学判定;血液鉴别光谱分析便携式整机系统研发等。对超连续激光光谱技术在生物医学领域的应用前景作了展望。     

激光扫描光学断层成像系统的设计与应用

设计了基于LabVIEW控制的激光扫描光学断层成像系统,该系统以准直激光器为光源,高精度四维平移台为样本定位单元,光电倍增管为采集单元,实现了针对小鼠肺等小尺寸样本的三维成像.该系统空间分辨率优于20μm,成像视野大于1cm,通过对离体小鼠肺器官的自发荧光成像,展示了系统的操作流程、成像结果和初步生物应用,并探索了它对整个生物器官组织的成像能力.与传统生物医学光学成像方法相比,该方法具有光子收集效率高、成像样本尺寸大、系统操作简单等优点.     

Near-infrared dyes as contrast-enhancing agents for spectroscopic optical coherence tomography

Optical coherence tomography (OCT) images of biological tissues often have low contrast. Spectroscopic optical coherence tomography (SOCT) methods have been developed to enhance contrast but remain limited because most tissues are not spectrally active in the frequency bands of laser sources commonly used in OCT. Near-infrared (NIR) dyes with absorption spectra features within the OCT source spectrum can be used for enhancing contrast in this situation. We introduce and demonstrate the use of NIR dyes as contrast agents for SOCT. Contrast-enhanced images are compared with fluorescence microscopy, demonstrating a link between SOCT and fluorescence imaging.     

The measurement of 3-D asymmetric temperature field by using real time laser interferometric tomography

A real time nondestructive temperature measurement technique based on laser holographic interference tomography technique is presented. An He–Ne laser is used as light source, and a CCD video camera is used to grab the interferogram. This laser holographic tomography technique is applied to the measurement of the temperature fields generated by two heated rods. Since data error is inevitable in engineering measurement, it is necessary to study the reconstruction techniques for reconstructing the temperature field. Three techniques including convolution back projection (CBP), algebra reconstruction technique (ART) and simultaneous iterative reconstruction technique (SIRT) are studied. Based on the reconstruction techniques and experimental situation, ART is used to reconstruct the asymmetric temperature fields. The thermocouples are used to measure the temperatures of the two heated rods. Comparing the reconstructed result with the measured temperature value, a satisfactory result is obtained.     

Application of the Monte Carlo method for modeling passage of ultrashort laser pulses through an inhomogeneous medium with moving scatterers

We present the results of numerical modeling of passage of ultrashort laser pulses through an inhomogeneous layered medium with moving scatterers, based on solution of the nonsteady-state radiation transport equation by the Monte Carlo method. We consider the effects of Doppler broadening of the backscattered radiation spectrum in biological tissues. We have analyzed the dynamics of propagation of a short laser pulse within a multilayer model of human skin. We have studied the possibilities for tomography of different layers of biological tissue based on analysis of the spectrum of the scattered radiation pulse.     

Synthesized optical coherence tomography for imaging of scattering objects by use of a stepwise frequency-modulated tunable laser diode

A technique named synthesized optical coherence tomography (SOCT) has been proposed and developed as an alternative method to the well-known optical coherence tomography for cross-sectional imaging of scattering objects. SOCT is based on the principle of synthesis of an optical coherence function by use of a tunable laser diode. With stepwise frequency modulation of light and synchronous phase modulation, the coherence function is synthesized into a peak at an arbitrary location. The longitudinal scattering distribution of the object under test is thus obtained without a mechanically driven reference. Two-dimensional tomography was demonstrated in a basic experiment with a lateral mechanical scan.     

Microstructure measurement based on frequency-shift feedback in a-cut Nd:YVO_4 laser

A new optical method based on frequency-shift feedback and laser confocal microscopy is presented to noninvasively measure a microstructure inside a sample. Due to the limit of axial resolution caused by poor signal detection ability, conventional laser feedback cannot precisely measure the microstructure. In this Letter, the light scattered by the sample is frequency shifted before feedback to the laser to obtain a magnification. Weak signals that change with the microstructure can be detected. Together with the tomography ability of laser confocal microscopy, the inner microstructure can be measured with high axial resolution.     

Recent Advances of Diffraction Tomography in Geophysics,Ultrasonics, and Optics

A tutorial review of diffraction tomography is given along with an overview of recent advances of this technique in borehole geophysics, ultrasonic imaging, and optical microscopy. First, the basic principles of diffraction tomography are presented. Then, we discuss a generalized inversion algorithm, valid for irregularly spaced data and a non-uniform background, and present reconstructions based on ultrasonic water tank data and underground georadar data. Next, we discuss a hybrid filtered backpropagation algorithm for ultrasonic and optical imaging. Quantitative images, based on experimental data, are presented of objects embedded in water or in biological tissue and probed by ultrasound, and of fibers embedded in an index matching liquid and probed by laser light.     

Applications of laser speckle photography for thermal flow problems

Laser speckle photography measures projected beam deflection of a phase object. The beam deflection measured at the solid surface will directly determine the wall-temperature gradient. Thus, the laser-speckle photography allows the evaluation of the convection-heat-transfer coefficients without the need to correct for conduction and radiation heat losses, which otherwise would be necessary. Selected results and brief discussions are presented for several natural convection-heat-transfer problems. Second, high-temperature applications of laser speckle photography shows potential as a nonintrusive means of measuring flame temperature. A fairly good agreement is shown in comparison of the laser speckle data with intrusive thermocouple data. Suggestive discussions are made to further improve the accuracy and sensitivity of the laser speckle photography technique in high-temperature applications. Finally, tomographic reconstruction of laser speckle photography data is discussed using both actual test fields and computer-synthesized phantom fields. The conventional algebraic reconstruction technique (ART) has been modified to apply for the laser speckle tomography. The efficacy of ART is examined particularly under a limited number of projections.     

Linear-wavenumber spectrometer for high-speed spectral-domain optical coherence tomography

An equidistant (in the wavenumber) spectrometer based on a diffraction grating, a compensation prism, and a CCD linear array is developed and implemented for spectral-domain optical coherence tomography. A criterion is introduced for estimating the level of residual nonequidistance. This criterion allows one to determine the threshold compensation level necessary for obtaining the spectrally limited spatial resolution. The method is tested in spectral-domain optical coherent tomography systems at wavelengths of 1270 and 830 nm.

     

Limited projections laser speckle tomography of complex flows

Different approaches are discussed applied to reconstruction of local flow parameters using line-of-sight laser probing. The first one is based on single projection measurement and detailed numerical simulation of flow pattern. The second one is based on multi-projectional line-of-sight measurement and reconstructing local flow parameters by solving inverse integral transforms. Holographic interferometry (HI) and speckle photography (SP) are used for laser probing of complex 3D media under study. Computer-assisted tomography (CAT) approach based on Radon integral transform is described and examples of reconstructed flowfields are given including compressible flows with shock waves. Statistical information about flow studied is extracted as well, and maps of local statistical turbulence parameters are quantitatively determined by using obtained SP-data and a new Erbeck–Merzkirch integral transform.     

Application of phase retrieval algorithm in reflective tomography laser radar imaging

We apply phase retrieval method to align projection data for tomographic reconstruction in reflective tomography laser radar imaging.In our experiment,the target is placed on a spin table with an unknown,but fixed,axis.The oscillatory motion of the target in the incident direction of the laser pulse is added at each view to simulate the real satellites random motion.The experimental simulation results demonstrate the effectiveness of this method to improve image reconstruction quality.Future research also includes the development of projection registration based on phase retrieval for targets with more complicated structure.     

Simultaneous determination of the spatial profile of the laser beam and vibrational-to-translational relaxation time by pulsed photoacoustics

Measuring the vibrational-to-translational relaxation time τ_V-T in gases is one of the applications of pulsed photoacoustic spectroscopy. Unfortunately, the spatial profile of the laser beam can significantly influence the accuracy of these measurements. Namely, minor changes in the spatial profile of the laser beam cause significant errors in the τ_V-T measuring. We present a method for simultaneous determination of the spatial profile of the laser beam and vibrational-to-translational relaxation time. It is based on the temporal shape of the photoacoustic pulse and utilizes a mathematical algorithm developed for photoacoustic tomography. PACS 39.30.+w; 82.80.Kq; 07.57.Ty     

基于法布里-珀罗调谐滤波器的傅里叶域锁模扫频激光光源

报道了一个光纤型1300 nm波段的傅里叶域锁模(Fourier domain mode locking, FDML)扫频激光光源, 用于扫频光学相干层析成像技术 (optical coherence tomography, OCT) 成像. 本实验扫频激光光源采用包含增益介质、调谐滤波器和延迟线组成的长腔激光谐振腔以及光功率增强单元. FDML扫频激光光源具有快速和高度稳定运转模式, 相位稳定性好. 基于法布里-珀罗调谐滤波器(fiber Fabry-Perot tunable filter, FFP-TF)的FDML扫频激光光源扫频范围为130 nm, 半高全宽为70 nm, 输出平均功率是11 mW. 与基于FFP-TF的短腔的扫频光源做了对比研究, FDML扫频光源速度从短腔的8 kHz提高到了48.12 kHz, 对应生物组织OCT成像轴向分辨率为7.8 μm, 比短腔的减小了1.9 μm. 关键词： 光学相干层析技术 扫频激光光源 傅里叶域锁模 法布里-珀罗调谐滤波器     

Noninvasive detection of inhomogeneities in turbid media with time-resolved log-slope analysis

Detecting foreign objects embedded in turbid media using noninvasive optical tomography techniques is of great importance in many practical applications, such as in biomedical imaging and diagnosis, safety inspection on aircrafts and submarines, and LIDAR techniques. In this paper we develop a novel optical tomography approach based on slope analysis of time-resolved back-scattered signals collected at the medium boundaries where the light source is an ultrafast, short-pulse laser. As the optical field induced by the laser-pulse propagates, the detected temporal signals are influenced by the optical properties of the medium traversed. The detected temporal signatures therefore contain information that can indicate the presence of an inhomogeneity as well as its size and location relative to the laser source and detection systems. The log-slope analysis of the time-resolved back-scattered intensity is shown to be an effective method for extracting the information contained in the signal. The technique is validated by experimental results and by Monte Carlo simulations.     

预混火焰前锋的观测及提取

介绍了用激光层析探测燃烧场的原理及其装置和图像处理工具的开发过程.利用预混V形火焰进行了激光层析探测火焰前锋的实验,结果显示该方法能够在入射光平面内清晰地分辨火焰皱褶在任一瞬间的几何形状.利用主动轮廓算法(ACM)从数字化图像中准确提取了火焰前锋的轮廓线形,为对火焰皱褶及其传播特性的量化分析打下了基础.     

Coherent combination of high-power, zigzag slab lasers

We demonstrate a scalable architecture for a high-power, high-brightness, solid-state laser based on coherent combinations of master oscillator power amplifier chains. A common master oscillator injects a sequence of multikilowatt Nd:YAG zigzag slab amplifiers. Adaptive optics correct the wavefront of each amplified beamlet. The beamlets are tiled side by side and actively phase locked to form a single output beam. The laser produces 19 kW with beam quality <2x diffraction limited. To the best of our knowledge, this is the brightest cw solid-state laser demonstrated to date.