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1.
Bao‐Hui Cheng Jian‐Chao Chen Jie‐Qing Liu Lin Zhou Ming‐Hua Qiu 《Helvetica chimica acta》2013,96(6):1111-1120
The six new cucurbitane‐type triterpenoids 1 – 6 , along with the ten known triterpenoids 7 – 16 , were isolated from the vines and leaves of Momordica charantia. The structures of the new compounds were elucidated as (3β,7β,15β,23E)‐3,7,15,25‐tetrahydroxycucurbita‐5,23‐dien‐19‐al ( 1 ), (3β,7β)‐3,7,22,23‐tetrahydroxycucurbita‐5,24‐dien‐19‐al ( 2 ), (3β,7β)‐3,7,23,24‐tetrahydroxycucurbita‐5,25‐dien‐19‐al ( 3 ), (3β,7β,23S)‐3,7,23‐trihydroxycucurbita‐5,24‐dien‐19‐al 7‐β‐D ‐glucopyranoside ( 4 ), (3β,7β,23E)‐cucurbita‐5,23‐diene‐3,7,19,25‐tetrol 7‐β‐D ‐glucopyranoside ( 5 ), and (3β,7β,23E)‐3,7‐dihydroxy‐25‐methoxy‐cucurbita‐5,23‐dien‐19‐al 3‐β‐D ‐allopyranoside ( 6 ), by extensive analyses of their spectral data, as well as by chemical methods. 相似文献
2.
Chiy‐Rong Chen Yun‐Wen Liao Wen‐Ling Shih Chih‐Ying Tzeng Hsueh‐Ling Cheng Wei‐Tsung Kao Chi‐I Chang 《Helvetica chimica acta》2010,93(7):1355-1361
Two new cucurbitane triterpenes, (23E)‐7β‐methoxycucurbita‐5,23,25‐trien‐3β‐ol ( 1 ) and 23,25‐dihydroxy‐5β,19‐epoxycucurbit‐6‐ene‐3,24‐dione ( 2 ), and a new D : C‐friedooleanane triterpene, 3α‐[(E)‐feruloyloxy]‐D : C‐friedooleana‐7,9(11)‐dien‐29‐oic acid ( 3 ), together with two known D : C‐friedooleanane triterpenes, 3β‐[(E)‐feruloyloxy]‐D : C‐friedooleana‐7,9(11)‐dien‐29‐oic acid ( 4 ) and 3‐oxo‐D : C‐friedooleana‐7,9(11)‐dien‐29‐oic acid ( 5 ), were isolated from the stems of Momordica charantia. The structures of the new compounds 1 – 3 were determined by spectroscopic methods. 相似文献
3.
Nguyen Xuan Nhiem Phan Van Kiem Chau Van Minh Ninh Khac Ban Nguyen Xuan Cuong Le Minh Ha Bui Huu Tai Tran Hong Quang Nguyen Huu Tung Young Ho Kim 《Magnetic resonance in chemistry : MRC》2010,48(5):392-396
The chemical study of Momordica charantia fruits led to the isolation of three new cucurbitane triterpene glycosides, momordicosides U, V, and W (1–3). The structures of these compounds were determined to be (19R, 23R)‐5β, 19‐epoxy‐19‐methoxycucurbita‐6,24‐diene‐3β, 23‐diol 3‐O‐β‐D‐allopyranoside (1), (23R)‐5β, 19‐epoxycucurbita‐6,24‐diene‐3β, 23‐diol 3‐O‐β‐D‐allopyranoside (2), and (19R)‐5β, 19‐epoxy‐19,25‐dihydroxycucurbita‐6,23(E)‐diene‐3β‐ol 3‐O‐β‐D‐glucopyranoside (3), by chemical and spectroscopic methods. Copyright © 2010 John Wiley & Sons, Ltd. 相似文献
4.
Zhen‐Jie Li Jian‐Chao Chen Yuan‐Yuan Deng Na‐Li Song Mu‐Yuan Yu Lin Zhou Ming‐Hua Qiu 《Helvetica chimica acta》2015,98(10):1456-1461
Two new cucurbitane triterpenoids, kuguacin X ( 1 ) and kuguaglycoside I ( 2 ), together with three known analogs, were isolated from immature fruits of Momordica charantia. By detailed analysis of IR, NMR, and MS data, acid hydrolysis, and comparison with spectroscopic data of known compounds, the new compounds were determined to be (23E)‐5β,19‐epoxycucurbita‐6,23‐diene‐3β,22ξ,25‐triol ( 1 ) and (23E)‐5β,19‐epoxycucurbita‐6,23‐dien‐19‐on‐3β,25‐diol 3‐O‐β‐D ‐allopyranoside ( 2 ). 相似文献
5.
Two new tetracyclic triterpenoids shiona‐19(E),21‐dien‐3β‐ol ( 1 ), and shiona‐22(29)‐en‐3β,21‐diol ( 2 ), together with four known compounds shiona‐21‐en‐3β‐ol ( 3 ), friedelinol ( 4 ), β‐sitosterol ( 5 ), and (24R)‐stigmast‐7,22(E)‐dien‐3a‐ol ( 6 ) were isolated from Aster ageratoides var. oophyllus. The structures of two new compounds were established on the basis of IR, MS, 1H, 13C and 2D NMR spectroscopic methods. 相似文献
6.
Yun‐Wen Liao Chiy‐Rong Chen Jue‐Liang Hsu Hsueh‐Ling Cheng Wen‐Ling Shih Yueh‐Hsiung Kuo Tzou‐Chi Huang Chi‐I Chang 《中国化学会会志》2011,58(7):893-898
A new sterol, 5α,6α‐epoxy‐3β‐hydroxy‐(22E,24R)‐ergosta‐8,22‐dien‐7‐one ( 1 ), together with eight known sterols, 5α,6α‐epoxy‐(22E,24R)‐ergosta‐8,22‐diene‐3β,7α‐diol ( 2 ), 5α,6α‐epoxy‐(22E,24R)‐ergosta‐8,22‐diene‐3β,7β‐diol ( 3 ), 5α,6α‐epoxy‐(22E,24R)‐ergosta‐8(14),22‐diene‐3β,7α‐diol ( 4 ), 3β‐hydroxy‐(22E,24R)‐ergosta‐5,8,22‐trien‐7‐one ( 5 ), ergosterol peroxide ( 6 ), clerosterol ( 7 ), decortinol ( 8 ), and decortinone ( 9 ), were isolated from the stems of Momordica charantia. Their structures were elucidated by mean of extensive spectroscopic methods, including 1H, 13C, 2D‐NMR and HR‐EI‐MS, as well as comparison with the literature data. Compounds 1 , 4 , 5 , 8 , and 91 were not cytotoxic against the SK‐Hep 1 cell line. 相似文献
7.
Three new triterpenoids with the rarely occurring nigrum skeleton, namely (20E)‐22‐hydroxynigrum‐20‐en‐3‐one ( 1 ), 21β‐hydroxynigrum‐22(29)‐en‐3‐one ( 2 ), and 21α‐hydroxynigrum‐22(29)‐en‐3‐one ( 3 ), were isolated from the mangrove plant Hibiscus tiliaceus. Additionally, five known triterpenoids including friedelin ( 4 ), 12‐oleanen‐3β‐ol ( 5 ), 3β‐hydroxy‐12‐oleanen‐28‐oic acid ( 6 ), 20(29)‐lupen‐3β,28‐diol ( 7 ), and cucurbita‐5,23‐dien‐3β,25‐diol ( 8 ) were also isolated and identified. The latter structures were elucidated by a detailed NMR and MS analyses, as well as by comparison with reported literature data. 相似文献
8.
A thorough investigation of Ligulariopsis shichuana afforded five new sesquiterpenes, including 1β,10β‐epoxy‐3α‐angeloyloxy‐9β‐acetoxy‐8α,11β‐dihydroxybakkenolide ( 1 ), 1β,7‐dihydroxy‐3β‐acetoxy‐noreremophil‐6(7),9(10)‐dien‐8‐one ( 2 ), 8α‐hydroxy‐3‐oxoeremophil‐1(2),7(11),9(10)‐trien‐8β(12)‐olide ( 3 ), 1β,10β‐dihydroxy‐3β‐acetoxyeremophil‐7(11),8(9)‐dien‐8(12)‐olide ( 4 ) and 1β,10β‐epoxy‐8,12‐dihydroxy‐3β‐acetoxy‐9β‐angeloyloxyeremophil‐7(11)‐en‐8,12‐disemiketal ( 5 ). Their structures were established by spectroscopic methods and 2D NMR techniques. In addition, bakkenolide ( 1 ) and eremophilenolides ( 5 ) showed antibacterial and cytotoxic activities. 相似文献
9.
Shu‐Hong Tao Jun Wu Shu‐Hua Qi Si Zhang Min‐Yi Li Qing‐Xin Li 《Helvetica chimica acta》2007,90(9):1718-1722
Two new iridoid glycosides, named scyphiphorins A ( 1 ) and B ( 2 ), together with four known compounds, geniposidic acid (=(1S,4aS,7aS)‐1‐(β‐D ‐glucopyranosyloxy)‐1,4a,5,7a‐tetrahydro‐7‐(hydroxymethyl)cyclopenta[c]pyran‐4‐carboxylic acid; 3 ), 4‐(4‐hydroxy‐3‐methoxybenzyl)butan‐2‐one, oleanolic acid (=(3β)‐3‐hydroxyolean‐12‐en‐28‐oic acid), and stigmasterol β‐D ‐glucoside (=(3β,22E)‐stigmasta‐5,22‐dien‐3‐yl β‐D ‐glucopyranoside), were isolated for the first time from the stem bark of a Chinese mangrove, Scyphiphora hydrophyllacea Gaertn . f. The structures of compounds 1 and 2 were determined as 10‐O‐benzoylgeniposidic acid and 10‐O‐[(2E,6R)‐8‐hydroxy‐2,6‐dimethyl‐1‐oxooct‐2‐en‐1‐yl]geniposidic acid, respectively, on the basis of spectroscopic data and chemical methods, including 2D NMR techniques. 相似文献
10.
From the whole plants of Parasenecio petasitoides, five new sesquiterpenoids were isolated, (E,E)‐3α,9β‐dihydroxy‐6βH,11βH‐13‐norgermacra‐1(10),4‐dien‐11,6‐carbolactone ( 2 ), (E,E)‐2α,9β‐dihydroxy‐6βH,11βH‐13‐norgermacra‐1(10),4‐dien‐11,6‐carbolactone ( 3 ), (E,E)‐2α,9β‐dihydroxy‐6βH,11αH‐13‐norgermacra‐1(10),4‐dien‐11,6‐carbolactone ( 4 ), (E)‐15‐hydroxy‐2‐oxo‐6βH,11αH‐13‐norguaia‐3‐ene‐11,6‐carbolactone ( 7 ), and (E)‐11β,15‐dihydroxy‐2‐oxo‐6βH‐13‐norguaia‐3‐ene‐11,6‐carbolactone ( 8 ), together with three known compounds, deacetyl herbolide A ( 1 ), jacquilenin ( 5 ), and (E)‐15‐hydroxy‐2‐oxo‐6βH,11βH‐13‐norguaia‐3‐ene‐11,6‐carbolactone ( 6 ). The structures of these natural products were elucidated spectroscopically, especially by 1D‐ and 2D‐NMR techniques, in combination with high‐resolution mass spectroscopy. 相似文献
11.
A novel lupane‐type triterpenoid, 3,4‐seco‐lupa‐4(23), 20(29)‐dien‐24‐hydroxy‐3‐oic acid (1) and a new cycloartane‐type triterpenoid, 23(E)‐cycloart‐23‐en‐25‐ethoxy‐3β‐ol (7), as well as eighteen known compounds, were isolated from the hot ethanol extract of the whole plant of Euphorbia humifusa Willd. The new structures were characterized by means of spectroscopic methods including 1D, 2D NMR and HRESIMS, and the known ones were established on the basis of comparing their NMR data with those of the corresponding compounds in the literature. In addition, cytotoxicity against selected cancer cell human gastric carcinoma (SGC‐7901) of compounds 1,3,4,6 were measured in vitro. 相似文献
12.
《Journal of separation science》2017,40(10):2238-2245
A rapid, effective method applying vortex‐assisted liquid–liquid microextraction before ultra‐high performance liquid chromatography with mass spectrometry and evaporative light scattering detection was developed for the analysis of four cucurbitane triterpenoids (momordicoside L, momordicoside K, momordicoside F2, and 3β,7β,25‐trihydroxy cucurbita‐5,23(E )‐dien‐19‐al) in bitter melon juices. Variables affecting the extraction efficiency including different extraction solvents, volume of extraction solvent, salt amount, acid condition, vortex speed and time were optimized thoroughly. Under the optimum conditions, precision was determined by the intra‐ and inter‐day tests in a range of 1.1–5.7% and 2.9–4.0% (RSD), respectively, with recoveries between 95.7 and 106.1%. The calibration curves showed good linearity with square correlation coefficient of 0.9936–0.9991 (evaporative light scattering detection) and 0.9858–0.9989 (MS). The detection limits ranged from 0.8–1.9 ng/mL (MS) to 3–10 ng/mL (evaporative light scattering detection) for these compounds. Enrichment factors of four target compounds were between 27 and 63 times. The proposed method was also used to determine the apparent solvent/water partition coefficients of analytes within the range of 53–120. The developed method can effectively enrich and quantify cucurbitane triterpenoids from bitter melon drinks. 相似文献
13.
Zhi‐Qiang Lu Guang‐Tong Chen Jin‐Qiang Zhang Hui‐Lian Huang Shu‐Hong Guan De‐An Guo 《Helvetica chimica acta》2007,90(11):2245-2250
Four new lanostane triterpenoids, namely (3β)‐3‐hydroxy‐24‐methylenelanost‐8‐ene‐7,11‐dione ( 1 ), (3β)‐3‐hydroxylanosta‐8,24‐diene‐7,11‐dione ( 2 ), (3β,7α)‐3,7‐dihydroxylanosta‐8,24‐dien‐11‐one ( 3 ), and (3β,11β)‐3,11‐dihydroxylanosta‐8,24‐dien‐7‐one ( 4 ) were isolated from Euphorbia humifusa, together with 2 known compounds. The structures of these new compounds were elucidated on the basis of extensive spectroscopic analysis and comparison with the related known compounds. 相似文献
14.
Tian‐Jye Hsieh Yang‐Chang Wu Su‐Ching Chen Ching‐Shan Huang Chung‐Yi Chen 《中国化学会会志》2004,51(4):869-876
A new kaurane diterpenoid, annoglabasin G (16α‐hydro‐19‐acetoxy‐ent‐kauran‐17‐al) ( 1 ), along with 27 compounds including 18 kaurane diterpenoids, 16β‐hydro‐ent‐kauran‐17‐oic acid ( 2 ), 16α‐hydro‐ent‐kauran‐17‐oic acid ( 3 ), 19‐nor‐ent‐kauran‐4α‐ol‐17‐oic acid ( 4 ), 16α‐hydro‐19‐ol‐ent‐kauran‐17‐oic acid ( 5 ), ent‐kaur‐16‐en‐19‐oic acid ( 6 ), 16α‐hydroxy‐ent‐kauran‐19‐oic acid ( 7 ), 16α,17‐dihydroxy‐ent‐kauran‐19‐oic acid ( 8 ), 16β,17‐dihydroxy‐ent‐kauran‐19‐oic acid ( 9 ), 16α‐hydro‐ent‐kauran‐17,19‐dioic acid ( 10 ), 16β‐hydroxy‐17‐acetoxy‐ent‐kauran‐19‐oic acid ( 11 ), 16β‐hydro‐17‐hydroxy‐ent‐kauran‐19‐al ( 12 ), 16α‐hydro‐17‐hydroxy‐ent‐kauran‐19‐al ( 13 ), 16β,17‐dihydroxy‐ent‐kauran‐19‐al ( 14 ), 16α‐hydro‐19‐al‐ent‐kauran‐17‐oic acid ( 15 ), 16α‐hydro‐17‐acetoxy‐ent‐kauran‐19‐al ( 16 ), 16α‐hydro‐19‐acetoxy‐ent‐kauran‐17‐oic acid ( 17 ), ent‐kaur‐15‐en‐19‐oic acid ( 18 ) and ent‐kaur‐15‐en‐17‐ol‐19‐oic acid ( 19 ); four acetogenins, annomontacin ( 20 ), annonacin ( 21 ), isoannonacinone ( 22 ) and squamocin ( 23 ); four steroids, β‐sitosterol ( 24 ), stigmasterol ( 25 ), β‐sitosteryl‐D‐glucoside ( 26 ) and stigmasteryl‐D‐glucoside ( 27 ) and one oxoaporphine, liriodenine ( 28 ), were isolated from the fresh fruits of Annona glabra. These compounds were characterized and identified by physical and spectral evidence. 相似文献
15.
Shu‐Min Yang Shao‐Hua Wu Xiang‐Dong Qin Xiao‐Dong Luo Da‐Gang Wu 《Helvetica chimica acta》2004,87(5):1279-1286
From the twigs of Amoora stellato‐squamosa, five new neoclerodane diterpenes have been isolated and characterized, methyl (13E)‐2‐oxoneocleroda‐3,13‐dien‐15‐oate (=methyl (2E)‐3‐methyl‐5‐[(1S,2R,4aR,8aR)‐1,2,3,4,4a,7,8,8a‐octahydro‐1,2,4a,5‐tetramethyl‐7‐oxo‐naphthalen‐1‐yl]pent‐2‐enoate; 1 ), (13E)‐2‐oxoneocleroda‐3,13‐dien‐15‐ol (=(4aR,7R,8S,8aR)‐1,2,4a,5,6,7,8,8a‐octahydro‐8‐[(E)‐5‐hydroxy‐3‐methylpent‐3‐enyl]‐4,4a,7,8‐tetramethylnaphthalen‐2(1H)‐one; 2 ), (3α,4β,13E)‐neoclerod‐13‐ene‐3,4,15‐triol (=(1R,2R,4aR, 5S,6R,8aR)‐decahydro‐5‐[(E)‐5‐hydroxy‐3‐methylpent‐3‐enyl]‐1,5,6,8a‐tetramethylnaphthalene‐1,2‐diol; 3 ), (3α,4β,13E)‐4‐ethoxyneoclerod‐13‐ene‐3,15‐diol (=(1R,2R,4aR,5S,6R,8aR)‐1‐ethoxydecahydro‐5‐[(E)‐5‐hydroxy‐3‐methylpent‐3‐enyl]‐1,5,6,8a‐tetramethylnaphthalen‐2‐ol; 4 ), and (3α,4β,14RS)‐neoclerod‐13(16)‐ ene‐3,4,14,15‐tetrol (=(1R,2R,4aR,5S,6R,8aR)‐decahydro‐5‐[3‐(1,2‐dihydroxyethyl)but‐3‐enyl]‐1,5,6,8a‐tetramethylnaphthalene‐1,2‐diol; 5 ), together with two known compounds, (13E)‐neocleroda‐3,13‐diene‐15,18‐diol ( 6 ) and (13S)‐2‐oxoneocleroda‐3,14‐dien‐13‐ol ( 7 ). 相似文献
16.
Haixue Kuang Bingyou Yang Ling Tang Yonggang Xia Deqiang Dou 《Helvetica chimica acta》2009,92(7):1315-1323
In search for bioactive compounds from the flower of Datura metel L., three new withanolide glucosides, namely baimantuoluosides A, B, and C ( 1 – 3 , resp.) were isolated. Enzymatic hydrolysis of 1 – 3 afforded the corresponding aglycones 1a, 2a , and 3a , respectively. The structures of the new compounds were elucidated as (5α,6α,7α,12β,22R)‐5,12‐dihydroxy‐1,26‐dioxo‐6,7 : 22,26‐diepoxyergosta‐2,24‐dien‐27‐yl β‐D ‐glucopyranoside ( 1 ), (5α,6α,7α,12α,22R)‐5,12‐dihydroxy‐1,26‐dioxo‐6,7 : 22,26‐diepoxyergosta‐2,24‐dien‐27‐yl β‐D ‐glucopyranoside ( 2 ), (5α,6α,7α,22R)‐5‐hydroxy‐1,26‐dioxo‐6,7 : 22,26‐diepoxyergosta‐2,24‐dien‐27‐yl β‐D ‐glucopyranoside ( 3 ) on the basis of chemical and physicochemical evidence, and are further confirmed by the structure determination by X‐ray diffraction of withanolide aglycone 1a . 相似文献
17.
Lon‐Je Luh Mohamed H. Abd El‐Razek Chia‐Ching Liaw Chen‐Tung Arthur Chen Yun‐Sheng Lin Yao‐Haur Kuo Ching‐Te Chien Ya‐Ching Shen 《Helvetica chimica acta》2009,92(7):1349-1358
Five new taxoids, including a new 2(3→20)‐abeo‐taxane with a 6/10/6‐membered ring system and four 3,8‐seco‐taxanes having a 6/12‐membered ring system, were isolated from an acetone extract of the leaves and twigs of the Taiwanese yew (Taxus sumatrana, Taxaceae). The structures were established as 2α,7β,10α‐triacetoxy‐5α‐hydroxy‐2(3→20)‐abeo‐taxa‐4(20),11‐dien‐9,13‐dione ( 1 ), (3E,8E)‐2α,9,10β, 13α,20‐pentaacetoxy‐7β‐hydroxy‐3,8‐secotaxa‐3,8,11‐trien‐5‐one ( 2 ), (3E,8E)‐2α,9,10β,13α,20‐pentaacetoxy‐5α,7β‐dihydroxy‐3,8‐secotaxa‐3,8,11‐triene ( 3 ), (3E,8E)‐9,10β,13α‐triacetoxy‐2α,7β,20‐trihydroxy‐5α‐[(2E)‐cinnamoyloxy]‐3,8‐secotaxa‐3,8,11‐triene ( 4 ), and (3E,8E)‐2α,5α,7β,9,10β,13α‐hexaacetoxy‐20‐hydroxy‐3,8‐secotaxa‐3,8,11‐triene ( 5 ), respectively, on the basis 1D‐ and 2D‐NMR spectral analyses. The in vitro cytotoxic activity of compounds 1 – 5 against four human tumor cell lines, including HeLa (cervical epitheloid), WiDr (colon), Daoy (medulloblastoma), and Hep2 (liver carcinoma) tumor cells was evaluated. Whereas compounds 1 – 3 were inactive, the novel taxanes 4 and 5 showed significant cytotoxicity. 相似文献
18.
A minor, unprecedented diterpene, 3β,17‐dihydroxycleistantha‐12,15‐dien‐2‐one ( 1 ), was isolated from the CHCl3‐soluble part of the EtOH extract of the pericarp of Trewia nudiflora. The structure of 1 was elucidated by means of 1D‐ and 2D‐NMR spectroscopic analyses as well as by HR‐MS. Also isolated were two known triterpenes, glutin‐5‐en‐3‐ol and olean‐18‐en‐3‐one (germanicone), as well as three known sterols, (22E,24R)‐5α,8α‐epidioxyergosta‐6,22‐dien‐3β‐ol, (22E,24R)‐5α,8α‐epidioxyergosta‐6,9(11),22‐trien‐3β‐ol, and (22E,24R)‐6‐methoxyergosta‐7,22‐dien‐3,5‐diol. 相似文献
19.
Hai‐Xue Kuang Qiu‐Hong Wang Bing‐You Yang Zhi‐Bin Wang Yoshihito Okada Tohru Okuyama 《Helvetica chimica acta》2011,94(12):2239-2247
Four new 9,10‐secocycloartane (=9,19‐cyclo‐9,10‐secolanostane) triterpenoidal saponins, named huangqiyenins G–J ( 1 – 4 , resp.), were isolated from Astragalus membranaceus Bunge leaves. The acid hydrolysis of 1 – 4 with 1M aqueous HCl yielded D ‐glucose, which was identified by GC analysis after treatment with L ‐cysteine methyl ester hydrochloride. The structures of 1 – 4 were established by detailed spectroscopic analysis as (3β,6α,10α,16β,24E)‐3,6‐bis(acetyloxy)‐10,16‐dihydroxy‐12‐oxo‐9,19‐cyclo‐9,10‐secolanosta‐9(11),24‐dien‐26‐yl β‐D ‐glucopyranoside ( 1 ), (3β,6a,10α,24E)‐3,6‐bis(acetyloxy)‐10‐hydroxy‐12,16‐dioxo‐9,19‐cyclo‐9,10‐secolanosta‐9(11),24‐dien‐26‐yl β‐D ‐glucopyranoside ( 2 ), (3β,6α,9α,10α,16β,24E)‐3,6‐bis(acetyloxy)‐9,10,16‐trihydroxy‐9,19‐cyclo‐9,10‐secolanosta‐11,24‐dien‐26‐yl β‐D ‐glucopyranoside ( 3 ), and (3β,6α,10α,24E)‐3,6‐bis(acetyloxy)‐10‐hydroxy‐16‐oxo‐9,19‐cyclo‐9,10‐secolanosta‐9(11),24‐dien‐26‐yl β‐D ‐glucopyranoside ( 4 ). 相似文献
20.
Zhi‐Zhi Du Pei‐Ji Zhao Hong‐Ping He Na Zhu Xiao‐Jiang Hao Yue‐Mao Shen 《Helvetica chimica acta》2005,88(9):2424-2429
Five ent‐atisane diterpenoids, including three new ones, i.e., (16α)‐17‐hydroxy‐ent‐atisan‐19‐oic acid methyl ester ( 1 ), (16α)‐17‐dihydroxy‐ent‐atisan‐19‐oic acid methyl ester ( 2 ), (16α)‐ent‐atisan‐16,17,19‐triol ( 3 ), and two known compounds, i.e., 17‐hydroxy‐ent‐atisan‐19‐oic acid ( 4 ), (16α)‐16,17‐dihydroxy‐ent‐atisan‐19‐al ( 5 ), together with one known diterpene glycoside, i.e., sumogaside, two known triterpenes, i.e., germanicone and (3β)‐β‐amyrin, three known phenolic compounds, i.e., (+)‐gallocatechin, (+)‐catechin, and gallic acid, and two known sterols, i.e., β‐sitosterol and daucosterol, were isolated from the callus cultures of Trewia nudiflora. Their structures were elucidated by spectroscopic analysis including 1D‐ and 2D‐NMR experiments. No maytansinoids were isolated or detected by LC‐ESI‐MS in the extracts of the calli, which suggests that the callus cultures can not produce maytansinoids under these conditions. 相似文献