Speech processing studies using an acoustic model of a multiple-channel cochlear implant

The speech perception of two multiple-channel cochlear implant patients was compared with that of three normally hearing listeners using an acoustic model of the implant for 22 different speech tests. The tests used included a minimal auditory capabilities battery, both closed-set and open-set word and sentence tests, speech tracking and a 12-consonant confusion study using nonsense syllables. The acoustic model represented electrical current pulses by bursts of noise and the effects of different electrodes were represented by using bandpass filters with different center frequencies. All subjects used a speech processor that coded the fundamental voicing frequency of speech as a pulse rate and the second formant frequency of speech as the electrode position in the cochlea, or the center frequency of the bandpass filter. Very good agreement was found for the two groups of subjects, indicating that the acoustic model is a useful tool for the development and evaluation of alternative cochlear implant speech processing strategies.     

Perceptual adaptation by normally hearing listeners to a simulated "hole" in hearing

Simulations of cochlear implants have demonstrated that the deleterious effects of a frequency misalignment between analysis bands and characteristic frequencies at basally shifted simulated electrode locations are significantly reduced with training. However, a distortion of frequency-to-place mapping may also arise due to a region of dysfunctional neurons that creates a "hole" in the tonotopic representation. This study simulated a 10 mm hole in the mid-frequency region. Noise-band processors were created with six output bands (three apical and three basal to the hole). The spectral information that would have been represented in the hole was either dropped or reassigned to bands on either side. Such reassignment preserves information but warps the place code, which may in itself impair performance. Normally hearing subjects received three hours of training in two reassignment conditions. Speech recognition improved considerably with training. Scores were much lower in a baseline (untrained) condition where information from the hole region was dropped. A second group of subjects trained in this dropped condition did show some improvement; however, scores after training were significantly lower than in the reassignment conditions. These results are consistent with the view that speech processors should present the most informative frequency range irrespective of frequency misalignment.     

Ipsilateral masking between acoustic and electric stimulations

Residual acoustic hearing can be preserved in the same ear following cochlear implantation with minimally traumatic surgical techniques and short-electrode arrays. The combined electric-acoustic stimulation significantly improves cochlear implant performance, particularly speech recognition in noise. The present study measures simultaneous masking by electric pulses on acoustic pure tones, or vice versa, to investigate electric-acoustic interactions and their underlying psychophysical mechanisms. Six subjects, with acoustic hearing preserved at low frequencies in their implanted ear, participated in the study. One subject had a fully inserted 24 mm Nucleus Freedom array and five subjects had Iowa/Nucleus hybrid implants that were only 10 mm in length. Electric masking data of the long-electrode subject showed that stimulation from the most apical electrodes produced threshold elevations over 10 dB for 500, 625, and 750 Hz probe tones, but no elevation for 125 and 250 Hz tones. On the contrary, electric stimulation did not produce any electric masking in the short-electrode subjects. In the acoustic masking experiment, 125-750 Hz pure tones were used to acoustically mask electric stimulation. The acoustic masking results showed that, independent of pure tone frequency, both long- and short-electrode subjects showed threshold elevations at apical and basal electrodes. The present results can be interpreted in terms of underlying physiological mechanisms related to either place-dependent peripheral masking or place-independent central masking.     

Effects of the salience of pitch and periodicity information on the intelligibility of four-channel vocoded speech: implications for cochlear implants

Recent simulations of continuous interleaved sampling (CIS) cochlear implant speech processors have used acoustic stimulation that provides only weak cues to pitch, periodicity, and aperiodicity, although these are regarded as important perceptual factors of speech. Four-channel vocoders simulating CIS processors have been constructed, in which the salience of speech-derived periodicity and pitch information was manipulated. The highest salience of pitch and periodicity was provided by an explicit encoding, using a pulse carrier following fundamental frequency for voiced speech, and a noise carrier during voiceless speech. Other processors included noise-excited vocoders with envelope cutoff frequencies of 32 and 400 Hz. The use of a pulse carrier following fundamental frequency gave substantially higher performance in identification of frequency glides than did vocoders using envelope-modulated noise carriers. The perception of consonant voicing information was improved by processors that preserved periodicity, and connected discourse tracking rates were slightly faster with noise carriers modulated by envelopes with a cutoff frequency of 400 Hz compared to 32 Hz. However, consonant and vowel identification, sentence intelligibility, and connected discourse tracking rates were generally similar through all of the processors. For these speech tasks, pitch and periodicity beyond the weak information available from 400 Hz envelope-modulated noise did not contribute substantially to performance.     

Perceptual learning following changes in the frequency-to-electrode assignment with the Nucleus-22 cochlear implant

The goal of the present study was to investigate the time course of adaptation by experienced cochlear implant users to a shifted frequency-to-electrode assignment in their speech processors. Speech recognition performance of three Nucleus-22 cochlear implant users was measured over a 3-month period, during which the implant listeners continuously wore "experimental" speech processors that were purposely shifted by 2-4 mm in terms of the frequency-to-electrode assignment relative to their normal processor. Baseline speech performance was measured with each subject's clinically assigned speech processor just prior to implementation of the experimental processor. Baseline speech performance was measured again after the 3-month test period, immediately following the reinstallation of the clinically assigned processor settings. Speech performance with the experimental processor was measured four times during the first week, and weekly thereafter over the 3-month period. Results showed that the experimental processor produced significantly lower performance on all measures of speech recognition immediately following implementation. Over the 3-month test period, consonant and HINT sentence recognition with the experimental processors gradually approached a performance level comparable to but still significantly below the baseline and postexperiment measures made with the clinically assigned processor. However, vowel and TIMIT sentence recognition with the experimental processors remained far below the level of the baseline measures even at the end of the 3-month experimental period. There was no significant change in performance with the clinically assigned processor before or after fitting with the experimental processor. The results suggest that a long-time exposure to a new pattern of stimulation may not be able to compensate for the deficit in performance caused by a 2-4-mm shift in the tonotopic location of stimulation, at least within a 3-month period.     

Frequency-to-electrode allocation and speech perception with cochlear implants

The hypothesis was investigated that selectively increasing the discrimination of low-frequency information (below 2600 Hz) by altering the frequency-to-electrode allocation would improve speech perception by cochlear implantees. Two experimental conditions were compared, both utilizing ten electrode positions selected based on maximal discrimination. A fixed frequency range (200-10513 Hz) was allocated either relatively evenly across the ten electrodes, or so that nine of the ten positions were allocated to the frequencies up to 2600 Hz. Two additional conditions utilizing all available electrode positions (15-18 electrodes) were assessed: one with each subject's usual frequency-to-electrode allocation; and the other using the same analysis filters as the other experimental conditions. Seven users of the Nucleus CI22 implant wore processors mapped with each experimental condition for 2-week periods away from the laboratory, followed by assessment of perception of words in quiet and sentences in noise. Performance with both ten-electrode maps was significantly poorer than with both full-electrode maps on at least one measure. Performance with the map allocating nine out of ten electrodes to low frequencies was equivalent to that with the full-electrode maps for vowel perception and sentences in noise, but was worse for consonant perception. Performance with the evenly allocated ten-electrode map was equivalent to that with the full-electrode maps for consonant perception, but worse for vowel perception and sentences in noise. Comparison of the two full-electrode maps showed that subjects could fully adapt to frequency shifts up to ratio changes of 1.3, given 2 weeks' experience. Future research is needed to investigate whether speech perception may be improved by the manipulation of frequency-to-electrode allocation in maps which have a full complement of electrodes in Nucleus implants.     

Frequency-place compression and expansion in cochlear implant listeners

In multichannel cochlear implants, low frequency information is delivered to apical cochlear locations while high frequency information is delivered to more basal locations, mimicking the normal acoustic tonotopic organization of the auditory nerves. In clinical practice, little attention has been paid to the distribution of acoustic input across the electrodes of an individual patient that might vary in terms of spacing and absolute tonotopic location. In normal-hearing listeners, Ba?kent and Shannon (J. Acoust. Soc. Am. 113, 2003) simulated implant signal processing conditions in which the frequency range assigned to the array was systematically made wider or narrower than the simulated stimulation range in the cochlea, resulting in frequency-place compression or expansion, respectively. In general, the best speech recognition was obtained when the input acoustic information was delivered to the matching tonotopic place in the cochlea with least frequency-place distortion. The present study measured phoneme and sentence recognition scores with similar frequency-place manipulations in six Med-El Combi 40+ implant subjects. Stimulation locations were estimated using the Greenwood mapping function based on the estimated electrode insertion depth. Results from frequency-place compression and expansion with implants were similar to simulation results, especially for postlingually deafened subjects, despite the uncertainty in the actual stimulation sites of the auditory nerves. The present study shows that frequency-place mapping is an important factor in implant performance and an individual implant patient's map could be optimized with functional tests using frequency-place manipulations.     

Recognition of spectrally degraded and frequency-shifted vowels in acoustic and electric hearing

The present study measured the recognition of spectrally degraded and frequency-shifted vowels in both acoustic and electric hearing. Vowel stimuli were passed through 4, 8, or 16 bandpass filters and the temporal envelopes from each filter band were extracted by half-wave rectification and low-pass filtering. The temporal envelopes were used to modulate noise bands which were shifted in frequency relative to the corresponding analysis filters. This manipulation not only degraded the spectral information by discarding within-band spectral detail, but also shifted the tonotopic representation of spectral envelope information. Results from five normal-hearing subjects showed that vowel recognition was sensitive to both spectral resolution and frequency shifting. The effect of a frequency shift did not interact with spectral resolution, suggesting that spectral resolution and spectral shifting are orthogonal in terms of intelligibility. High vowel recognition scores were observed for as few as four bands. Regardless of the number of bands, no significant performance drop was observed for tonotopic shifts equivalent to 3 mm along the basilar membrane, that is, for frequency shifts of 40%-60%. Similar results were obtained from five cochlear implant listeners, when electrode locations were fixed and the spectral location of the analysis filters was shifted. Changes in recognition performance in electrical and acoustic hearing were similar in terms of the relative location of electrodes rather than the absolute location of electrodes, indicating that cochlear implant users may at least partly accommodate to the new patterns of speech sounds after long-time exposure to their normal speech processor.     

Recognition of spectrally asynchronous speech by normal-hearing listeners and Nucleus-22 cochlear implant users

This experiment examined the effects of spectral resolution and fine spectral structure on recognition of spectrally asynchronous sentences by normal-hearing and cochlear implant listeners. Sentence recognition was measured in six normal-hearing subjects listening to either full-spectrum or noise-band processors and five Nucleus-22 cochlear implant listeners fitted with 4-channel continuous interleaved sampling (CIS) processors. For the full-spectrum processor, the speech signals were divided into either 4 or 16 channels. For the noise-band processor, after band-pass filtering into 4 or 16 channels, the envelope of each channel was extracted and used to modulate noise of the same bandwidth as the analysis band, thus eliminating the fine spectral structure available in the full-spectrum processor. For the 4-channel CIS processor, the amplitude envelopes extracted from four bands were transformed to electric currents by a power function and the resulting electric currents were used to modulate pulse trains delivered to four electrode pairs. For all processors, the output of each channel was time-shifted relative to other channels, varying the channel delay across channels from 0 to 240 ms (in 40-ms steps). Within each delay condition, all channels were desynchronized such that the cross-channel delays between adjacent channels were maximized, thereby avoiding local pockets of channel synchrony. Results show no significant difference between the 4- and 16-channel full-spectrum speech processor for normal-hearing listeners. Recognition scores dropped significantly only when the maximum delay reached 200 ms for the 4-channel processor and 240 ms for the 16-channel processor. When fine spectral structures were removed in the noise-band processor, sentence recognition dropped significantly when the maximum delay was 160 ms for the 16-channel noise-band processor and 40 ms for the 4-channel noise-band processor. There was no significant difference between implant listeners using the 4-channel CIS processor and normal-hearing listeners using the 4-channel noise-band processor. The results imply that when fine spectral structures are not available, as in the implant listener's case, increased spectral resolution is important for overcoming cross-channel asynchrony in speech signals.     

Channel weights for speech recognition in cochlear implant users

The purpose of this study was to develop and validate a method of estimating the relative "weight" that a multichannel cochlear implant user places on individual channels, indicating its contribution to overall speech recognition. The correlational method as applied to speech recognition was used both with normal-hearing listeners and with cochlear implant users fitted with six-channel speech processors. Speech was divided into frequency bands corresponding to the bands of the processor and a randomly chosen level of corresponding filtered noise was added to each channel on each trial. Channels in which the signal-to-noise ratio was more highly correlated with performance have higher weights, and conversely, channels in which the correlations were smaller have lower weights. Normal-hearing listeners showed approximately equal weights across frequency bands. In contrast, cochlear implant users showed unequal weighting across bands, and varied from individual to individual with some channels apparently not contributing significantly to speech recognition. To validate these channel weights, individual channels were removed and speech recognition in quiet was tested. A strong correlation was found between the relative weight of the channel removed and the decrease in speech recognition, thus providing support for use of the correlational method for cochlear implant users.     

Assessing the pitch structure associated with multiple rates and places for cochlear implant users

Cochlear implant subjects continue to experience difficulty understanding speech in noise and performing pitch-based musical tasks. Acoustic model studies have suggested that transmitting additional fine structure via multiple stimulation rates is a potential mechanism for addressing these issues [Nie et al., IEEE Trans. Biomed. Eng. 52, 64-73 (2005); Throckmorton et al., Hear. Res. 218, 30-42 (2006)]; however, results from preliminary cochlear implant studies have been less compelling. Multirate speech processing algorithms previously assumed a place-dependent pitch structure in that a basal electrode would always elicit a higher pitch percept than an apical electrode, independent of stimulation rate. Some subjective evidence contradicts this assumption [H. J. McDermott and C. M. McKay, J. Acoust. Soc. Am. 101, 1622-1630 (1997); R. V. Shannon, Hear. Res. 11, 157-189 (1983)]. The purpose of this study is to test the hypothesis that the introduction of multiple rates may invalidate the tonotopic pitch structure resulting from place-pitch alone. The SPEAR3 developmental speech processor was used to collect psychophysical data from five cochlear implant users to assess the tonotopic structure for stimuli presented at two rates on all active electrodes. Pitch ranking data indicated many cases where pitch percepts overlapped across electrodes and rates. Thus, the results from this study suggest that pitch-based tuning across rate and electrode may be necessary to optimize performance of a multirate sound processing strategy in cochlear implant subjects.     

Effects of modulation wave shape on modulation frequency discrimination with electrical hearing

Amplitude modulations of pulsitile stimulation can be used to convey pitch information to cochlear implant users. One variable in designing cochlear implant speech processors is the choice of modulation waveform used to convey pitch information. Modulation frequency discrimination thresholds were measured for 100 Hz modulations with four waveforms (sine, sawtooth, a sharpened sawtooth, and square). Just-noticeable differences (JNDs) were similar for all but the square waveform, which often produced larger JNDs. The results suggest that a sine, sawtooth, and sharpened sawtooth waveforms are likely to provide similar pitch discrimination within a speech processing strategy.     

Effect of stimulation rate on phoneme recognition by nucleus-22 cochlear implant listeners

This study investigated the effect of pulsatile stimulation rate on medial vowel and consonant recognition in cochlear implant listeners. Experiment 1 measured phoneme recognition as a function of stimulation rate in six Nucleus-22 cochlear implant listeners using an experimental four-channel continuous interleaved sampler (CIS) speech processing strategy. Results showed that all stimulation rates from 150 to 500 pulses/s/electrode produced equally good performance, while stimulation rates lower than 150 pulses/s/electrode produced significantly poorer performance. Experiment 2 measured phoneme recognition by implant listeners and normal-hearing listeners as a function of the low-pass cutoff frequency for envelope information. Results from both acoustic and electric hearing showed no significant difference in performance for all cutoff frequencies higher than 20 Hz. Both vowel and consonant scores dropped significantly when the cutoff frequency was reduced from 20 Hz to 2 Hz. The results of these two experiments suggest that temporal envelope information can be conveyed by relatively low stimulation rates. The pattern of results for both electrical and acoustic hearing is consistent with a simple model of temporal integration with an equivalent rectangular duration (ERD) of the temporal integrator of about 7 ms.     

The effect of channel interactions on speech recognition in cochlear implant subjects: predictions from an acoustic model

Acoustic models that produce speech signals with information content similar to that provided to cochlear implant users provide a mechanism by which to investigate the effect of various implant-specific processing or hardware parameters independent of other complicating factors. This study compares speech recognition of normal-hearing subjects listening through normal and impaired acoustic models of cochlear implant speech processors. The channel interactions that were simulated to impair the model were based on psychophysical data measured from cochlear implant subjects and include pitch reversals, indiscriminable electrodes, and forward masking effects. In general, spectral interactions degraded speech recognition more than temporal interactions. These effects were frequency dependent with spectral interactions that affect lower-frequency information causing the greatest decrease in speech recognition, and interactions that affect higher-frequency information having the least impact. The results of this study indicate that channel interactions, quantified psychophysically, affect speech recognition to different degrees. Investigation of the effects that channel interactions have on speech recognition may guide future research whose goal is compensating for psychophysically measured channel interactions in cochlear implant subjects.     

Localization by interaural time difference (ITD): effects of interaural frequency mismatch.

A commonly accepted physiological model for lateralization of low-frequency sounds by interaural time delay (ITD) stipulates that binaural comparison neurons receive input from frequency-matched channels from each ear. Here, the effects of hypothetical interaural frequency mismatches on this model are reported. For this study, the cat's auditory system peripheral to the binaural comparison neurons was represented by a neurophysiologically derived model, and binaural comparison neurons were represented by cross-correlators. The results of the study indicate that, for binaural comparison neurons receiving input from one cochlear channel from each ear, interaural CF mismatches may serve to either augment or diminish the effective difference in ipsilateral and contralateral axonal time delays from the periphery to the binaural comparison neuron. The magnitude of this increase or decrease in the effective time delay difference can be up to 400 microseconds for CF mismatches of 0.2 octaves or less for binaural neurons with CFs between 250 Hz and 2.5 kHz. For binaural comparison neurons with nominal CFs near 500 Hz, the 25-microsecond effective time delay difference caused by a 0.012-octave CF mismatch is equal to the ITD previously shown to be behaviorally sufficient for the cat to lateralize a low-frequency sound source.     

Synthetic vowel studies on cochlear implant patients

Speech perception studies were conducted on three cochlear implant patients to investigate the relative merits of six speech processing schemes for presenting speech information to these patients. Electrical stimuli, described in this article as synthetic vowels, were constructed using tabulated data of formant frequencies of natural vowels. The six schemes differed in the number of formant frequencies encoded on the electrical signal dimension of electrode position, and/or in the range of electrode position used for encoding each formant frequency. Eleven synthetic vowels (i, I, E, ae, a, c, U, u, v, E, D) were used and were presented in a single-interval procedure for absolute identification. Single-formant vowels were used in two of the six schemes, two-formant vowels in three schemes, and three-formant vowels in the remaining scheme. The confusion matrices were subjected to conditional information transmission analysis on the basis of previous psychophysiological findings. Comparisons among the schemes in terms of the analyzed results showed that training, experience, and adaptability to new speech processing schemes were major factors influencing the identification of synthetic vowels. For vowels containing more than one formant, the information about each formant affected the perception of the other formants. In addition, there appeared to be differences between the perceptual processes for vowels containing more than one formant and the processes for single-formant vowels. Taking into consideration the effects of training, experience, and adaptability, the three-formant speech processing scheme appeared, on the basis of perceptual performance comparisons among the six schemes, to be the logical choice for implementation in speech processors for cochlear implant patients.     

Rate and timing cues associated with the cochlear amplifier: level discrimination based on monaural cross-frequency coincidence detection.

The perceptual significance of the cochlear amplifier was evaluated by predicting level-discrimination performance based on stochastic auditory-nerve (AN) activity. Performance was calculated for three models of processing: the optimal all-information processor (based on discharge times), the optimal rate-place processor (based on discharge counts), and a monaural coincidence-based processor that uses a non-optimal combination of rate and temporal information. An analytical AN model included compressive magnitude and level-dependent-phase responses associated with the cochlear amplifier, and high-, medium-, and low-spontaneous-rate (SR) fibers with characteristic frequencies (CFs) spanning the AN population. The relative contributions of nonlinear magnitude and nonlinear phase responses to level encoding were compared by using four versions of the model, which included and excluded the nonlinear gain and phase responses in all possible combinations. Nonlinear basilar-membrane (BM) phase responses are robustly encoded in near-CF AN fibers at low frequencies. Strongly compressive BM responses at high frequencies near CF interact with the high thresholds of low-SR AN fibers to produce large dynamic ranges. Coincidence performance based on a narrow range of AN CFs was robust across a wide dynamic range at both low and high frequencies, and matched human performance levels. Coincidence performance based on all CFs demonstrated the "near-miss" to Weber's law at low frequencies and the high-frequency "mid-level bump." Monaural coincidence detection is a physiologically realistic mechanism that is extremely general in that it can utilize AN information (average-rate, synchrony, and nonlinear-phase cues) from all SR groups.     

Acoustic parameters measured by a formant-estimating speech processor for a multiple-channel cochlear implant

In order to assess the limitations imposed on a cochlear implant system by a wearable speech processor, the parameters extracted from a set of 11 vowels and 24 consonants were examined. An estimate of the fundamental frequency EF 0 was derived from the zero crossings of the low-pass filtered envelope of the waveform. Estimates of the first and second formant frequencies EF 1 and EF 2 were derived from the zero crossings of the waveform, which was filtered in the ranges 300-1000 and 800-4000 Hz. Estimates of the formant amplitudes EA 1 and EA 2 were derived by peak detectors operating on the outputs of the same filters. For vowels, these parameters corresponded well to the first and second formants and gave sufficient information to identify each vowel. For consonants, the relative levels and onset times of EA 1 and EA 2 and the EF 0 values gave cues to voicing. The variation in time of EA 1, EA 2, EF 1, and EF 2 gave cues to the manner of articulation. Cues to the place of articulation were given by EF 1 and EF 2. When pink noise was added, the parameters were gradually degraded as the signal-to-noise ratio decreased. Consonants were affected more than vowels, and EF 2 was affected more than EF 1. Results for three good patients using a speech processor that coded EF 0 as an electric pulse rate, EF 1 and EF 2 as electrode positions, and EA 1 and EA 2 as electric current levels confirmed that the parameters were useful for recognition of vowels and consonants. Average scores were 76% for recognition of 11 vowels and 71% for 12 consonants in the hearing-alone condition. The error rates were 4% for voicing, 12% for manner, and 25% for place.     

Forward masking patterns produced by intracochlear electrical stimulation of one and two electrode pairs in the human cochlea

Three psychophysical forward masking studies were conducted on a multichannel cochlear implant patient. The first study investigated the masking pattern produced by a bipolar electrode pair at different stimulus currents. It was found that the masking pattern for a single-masker bipolar electrode pair had a maximum located at an electrode position where the masker and probe coincided. The spread of the masking pattern was not symmetrical about the maximum. The amount of masking decreased very rapidly toward the apical direction and less rapidly toward the basal direction from the position of the maximum. As the stimulus current increased, the amount of masking at the maximum increased and the masking pattern broadened toward the base. The second study investigated the masking pattern produced by the activation of single bipolar electrode pairs with different spatial extents. The spatial extent of a bipolar electrode pair is defined as the distance between the apical and basal electrode members of the bipolar pair. With a small spatial extent (1.5 mm), the more basal electrode pairs (higher threshold and smaller dynamic range) produced broader masking patterns than the more apical electrode pairs (lower threshold and wider dynamic range), suggesting that there was more current spread at the basal region. With a larger spatial extent (4.5 mm), an additional secondary masking maximum was observed in the vicinity of the apical electrode member of the masker; this was observed only when the apical electrode member lay within the low-threshold apical region. The third study investigated the masking patterns produced by two loudness balanced bipolar masker electrode pairs activated within a stimulus period (inverse of the pulse repetition rate). The biphasic current pulses delivered to the two electrode pairs were nonoverlapping in time. It was found that, at any probe electrode position, the amount of masking produced by the two combined bipolar electrode pairs approximately followed the greater of the two maskings produced respectively by the two individual bipolar masker electrode pairs.     

Basilar membrane mechanics at the base of the chinchilla cochlea. I. Input-output functions, tuning curves, and response phases

Basilar membrane (BM) velocity was measured at a site 3.5 mm from the basal end of the chinchilla cochlea using the M?ssbauer technique. The threshold of the compound action potential recorded at the round window in response to tone bursts was used as an indicator of the physiological state of the cochlea. The BM input-output functions display a compressive nonlinearity for frequencies around the characteristic frequency (CF, 8 to 8.75 kHz), but are linear for frequencies below 7 and above 10.5 kHz. In preparations with little surgical damage, isovelocity tuning curves at 0.1 mm/s are sharply tuned, have Q10's of about 6, minima as low as 13 dB SPL, tip-to-tail ratios (at 1 kHz) of 56 to 76 dB, and high-frequency slopes of about 300 dB/oct. These mechanical responses are as sharply tuned as frequency-threshold curves of chinchilla auditory nerve fibers with corresponding CF. There is a progressive loss of sensitivity of the mechanical response with time for the frequencies around CF, but not for frequencies on the tail of the tuning curve. In some experiments the nonlinearity was maintained for several hours, in spite of a considerable loss of sensitivity of the BM response. High-frequency plateaus were observed in both isovelocity tuning curves and phase-frequency curves.