共查询到20条相似文献,搜索用时 15 毫秒
1.
A new steroidal alkaloid, 4-dehydroxyepisarcovagine A (1), along with seven known alkaloids, sarcovagine D (2), sarcovagenine C (3), epoxysarcovagenine D (4), Pachysamine L (5), Pachysamine E (6), sarcovagine A (7) and sarcovagine B (8), was isolated from the roots and stems of Sarcococca pruniformis Lindl. The structure of compound 1 was elucidated by means of spectroscopic analysis. 相似文献
2.
Khairitdinova E. D. Tsirlina E. M. Spirikhin L. V. Fedorov N. I. Efremov Yu. Ya. Yunusov M. S. 《Russian Chemical Bulletin》2003,52(9):2078-2080
A new norditerpenoid alkaloid has been isolated from the roots of Delphinium cuneatum. On the basis of 1H, 13C NMR, IR, and mass spectra, the structure of the alkaloid was established as 1,6,14-trimethoxy-7,8-dihydroxy-18-(2-methyl)succinylanthranoyloxyaconane (16-demethoxymethyllycaconitine). The roots of Delphinium cuneatum also contain the known alkaloid methyllycaconitine and N,N"-di(methoxycarbonyl)-3,4-diaminotoluene. 相似文献
3.
4.
This phytochemical study of stems and leaves of Erythrina stricta led to the isolation of twenty-three alkaloids, one of them previously unreported, 11β-hydroxyerythratidine N-oxide. Their structures were elucidated on the basis of extensive 1D and 2D NMR spectroscopic analyses including HSQC, HMBC, 1H–1H COSY, NOESY, as well as HRESIMS data in addition to comparison with reports in the literature. 相似文献
5.
T. M. Gabbasov E. M. Tsyrlina L. V. Spirikhin N. I. Fedorov M. S. Yunusov 《Chemistry of Natural Compounds》2008,44(4):472-474
The new norditerpene alkaloid uraphine, for which the structure 1α,6β-dihydroxy-7,8-methylenedioxy-14α,16β,18β-trimethoxy-N-ethylaconitane
was proposed based on PMR,
13
C NMR, IR, and mass spectral data, was isolated from the aerial part of Delphinium uralense N. The known alkaloids dehydrodelcorine,
delpheline, deltaline, deltamine, elasine, deacetylelasine, gigactonine, and lycoctonine were also isolated from the total
alkaloids.
Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 380-382, July-August, 2008. 相似文献
6.
A new benzylisoquinoline alkaloid from stems of Nelumbo nucifera 总被引:2,自引:0,他引:2
Xu Hong Duan Jian Qin Jiang~* Department of Natural Medicine Chemistry China Pharmaceutical University Nanjing China 《中国化学快报》2008,19(3):308-310
A new benzylisoquinoline alkaloid, named nelumstemine (1), 1-(4'-hydroxybenzoyl)-6,7-dimethoxy-3,4-dihydroisoquinoline, was isolated from the stems of Nelumbo nucifera Geartn. Its structure was established on the basis of spectral analysis. 相似文献
7.
Takaaki Kubota Tetsuro Yasuda Jane Fromont Yuzuru Mikami Jun’ichi Kobayashi 《Tetrahedron letters》2009,50(52):7268-207
A new dimeric bromopyrrole alkaloid possessing a benzocyclobutane ring, benzosceptrin C (1), has been isolated from an Okinawan marine sponge of the genus Agelas (SS-956), and the structure and relative stereochemistry were elucidated from spectroscopic data. Benzosceptrin C (1) showed antimicrobial activity. 相似文献
8.
Olusegun S. Ajala Andrew M. PiggottFabien Plisson Zeinab KhalilXiao-cong Huang Sunday A. AdesegunHerbert A.B. Coker Robert J. Capon 《Tetrahedron letters》2011,52(52):7125-7127
Chemical investigations into samples of Hunteria umbellata (K. Schum) collected in Osun State, Nigeria, led to the discovery of a new indole alkaloid, ikirydinium A, featuring an unprecedented 3-alkylpyridinium-indole-2-carboxylate scaffold. Ikirydinium A was found to exhibit antimicrobial activity (IC50 0.6 μM) against Bacillus subtilis ATCC 6051. The involvement of a common intermediate in the biosynthesis of ikirydinium A and vinblastine is hypothesized. 相似文献
9.
Christian Wegner Matthias Hamburger Olaf Kunert Ernst Haslinger 《Helvetica chimica acta》2000,83(7):1454-1464
In the search for the cause for the formation of persistent foam in the Rhine River below the Rhine Fall at Schaffhausen, an investigation of the tensioactive principles from the aquatic plant Ranunculus fluitans L. (Ranunculaceae) was carried out. Two new (see 1 and 2 ) and four known bisdesmosidic triterpene saponins (see 4 – 6 ) were isolated along with the two known diacylglycerol galactosides 7 and 8 . The saponin structures were established by the identification of the aglycon and sugar moieties by HPLC and chiral capillary zone electrophoresis (CZE), ion‐spray LC/MS and extensive 1‐ and 2D homo‐ and heteronuclear NMR spectroscopy. The structures of the new oleanane‐type saponins were identified as 3‐O‐[β‐D ‐glucopyranosyl‐(1→3)‐α‐L ‐arabinopyranosyl]‐28‐O‐[α‐L ‐rhamnopyranosyl‐(1→4)‐β‐D ‐glucopyranosyl‐(1→6)‐β‐D ‐glucopyranosyl]hederagenin ( 1 ) and 3‐O‐[β‐D ‐glucopyranosyl‐(1→3)‐β‐D ‐glucopyranosyl]oleanolic acid [α‐L ‐rhamnopyranosyl‐(1→4)‐β‐D ‐glucopyranosyl‐(1→6)‐β‐D ‐glucopyranosyl] ester ( 2 ). LC/MS Studies of tensioactive fractions revealed the presence of additional glycoglycerolipids. 相似文献
10.
Two new Lycopodium alkaloids, 4β-hydroxynankakurine B (1) and Δ13,N,Nα-methylphlegmarine-Nβ-oxide (2), together with three known analogues, lycoposerramine E (3), nankakurine B (4) and lobscurinol (5), were isolated from Phlegmariurus phlegmaria. Their structures were established by mass spectrometry and 1D and 2D NMR techniques. 相似文献
11.
Tsvetelina Doncheva Nadezhda Kostova Violeta Valcheva Radostina Toshkovska Vassil Vutov Stefan Philipov 《Natural product research》2020,34(5):668-674
AbstractNew isoquinoline alkaloid hypepontine (1) together with a five known compounds, were identified in Hypecoum ponticum Velen, the partial synonym of Hypecoum procumbens L. The structure of the new substance was elucidated based on spectroscopic evidence. The tertiary and quaternary alkaloid mixtures as well as the isolated alkaloids were evaluated for their antibacterial and antifungal activity. The result revealed that the crude alkaloid mixture containing quaternary isoquinoline alkaloids showed potent antifungal and antibacterial activity. 相似文献
12.
A. S. Narzullaev N. D. Abdullaev M. S. Yunusov V. M. Matveev S. G. Yunusova 《Russian Chemical Bulletin》1997,46(1):184-185
A new alkaloid, ternatine (C24H33NO5), was isolated from aerial parts of theDelphinium ternatum plant. According to the1H,13C NMR, IR, and mass spectra of the base and its triacetate, ternative was assumed to have the structure of 4β-methyl-7α-isobutyryloxy-11α,15β,19β-trihydroxyhetisane.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 187–189, January, 1997. 相似文献
13.
14.
A new norditerpenoid alkaloid acsonine from the roots of Aconitum kusnezoffii Reichb. 总被引:3,自引:0,他引:3
Zinurova E. G. Khakimova T. V. Spirikhin L. V. Yunusov M. S. Gorovoi P. G. Tolstikov G. A. 《Russian Chemical Bulletin》2001,50(2):311-312
The known norditerpenoid alkaloid mesaconitine and a new alkaloid acsonine 1 were isolated from the roots of Aconitum kusnezoffii Reichb. The structure of 1 was established based on spectroscopic data. 相似文献
15.
Nadjet Mezache Hocine Laouer Pascal Richomme Denis Séraphin Salah Akkal 《Natural product research》2019,33(15):2182-2191
Alkaloids and phenolic compounds are among the most biologically active natural products from the Jacobaea/Senecio genera (Asteraceae). To isolate original natural products directly from Jacobaea gigantea crude polar extracts, centrifugal partition chromatography (CPC) was used. Previously, we reported the phytochemical study of J. gigantea (syn. Senecio giganteus) n-butanol extract using various classical chromatographical techniques combined with CPC. Herein major constituents from the J. gigantea crude ethyl acetate extract and further compounds from the n-butanol extract were purified in only one step using this technique. A new pyrrolidine alkaloid, named senecipyrrolidine was isolated along with thirteen known compounds – chiro-inositol, three phenolic acids, six flavonoids, two quinones and emiline, another pyrrolidine alkaloid – from crude n-butanol or ethyl acetate extracts. Pyrrolidine alkaloids were isolated for the first time in the Jacobaea/Senecio genera and were probably biogenetically related to the two isolated quinones derivatives jacaranone and 3a-hydroxy-3,3a,7,7a-tetrahydrobenzofuran-2,6-dione, isolated in this species. 相似文献
16.
A new denudatine-type C20-diterpenoid alkaloid, designated as sinchianine (1), together with eight known diterpenoid alkaloids, 12-acetyl-12-epi-napelline (2), 12-epi-napelline (3), neoline (4), talatisamine (5), 14-O-acetylsenbusine A (6) and benzoylaconine (7), songorine (8) and aconitine (9), were isolated from the whole herb of Aconitum sinchiangense W. T. Wang. Their structures were elucidated on the basis of extensive spectroscopic analyses (NMR and HR-ESI-MS) and comparison with data reported in the literature. 相似文献
17.
Wei-Wei Jiang Jia Su Xing-De Wu Juan He Li-Yan Peng Xiao Cheng 《Natural product research》2015,29(9):842-847
Geissoschizine methyl ether N-oxide, a new oxindole alkaloid, along with 14 known alkaloids, was isolated from the aerial part of Uncaria rhynchophylla. Their structures were identified by comprehensive spectral methods, including 2D NMR experiments, and confirmed by comparing with the literature data. In vitro acetylcholinesterase (AChE) inhibitory activity assay showed that the new compound exhibited anti-AChE activity with IC50 value of 23.4 μM. 相似文献
18.
A new alkaloid, (10E, 12E)-9-ureidooctadeca-10, 12-dienoic acid, named oleraurea (1) and 10 known compounds, p-hydroxybenzaldehyde (2), p-hydroxybenzoic acid (3), p-hydroxyacetophenone (4), benzamide (5), (E)-p-coumaramide (6), (E)-ferulamide (7), soyalkaloid A (8), β-carboline-3-carboxylic acid (9), 2, 3, 4, 9-tetrahydro-1H-pyrido [3, 4-b] indole-3-carboxylic acid (10), (1S, 3S)-1-methyl-1, 2, 3, 4-tetrahydro-β-carboline-3-carboxylic acid (11) were obtained from Portulaca oleracea L., in which, compounds 4, 5, 8–11 were isolated from the plant for the first time. The structure of the compound 1 was identified using spectroscopic methods including 1D and 2D NMR, HR-ESI-TOF-MS. The compounds 1, 5–11 presented anticholinesterase activities, but the P. oleracea extract (POE) presented very low anticholinesterase activity. 相似文献
19.
Chengcheng Zhao Zheming Ying Xiaojun Tao Mingyue Jiang 《Natural product research》2018,32(13):1548-1553
A new lactam alkaloid named oleraciamide D (1), indentified as (5R)-4-(3-methoxy-4-hydroxyphenyl)-5-(4-hydroxyphenyl)-5,6-dihydropyridin-2(1H)-one, together with five known compounds, indole-3-aldehyde (2), portulacatone (3), N-trans-feruloyloctopamine (4), N-trans-feruloyl-3′-O-methyldopamine (5) and N-trans-feruloyltyramine (6) were isolated from Potulaca oleracea L. Among them, indole-3-aldehyde (2) was isolated from the medicine for the first time. The structure of the new alkaloid was elucidated via UHPLC-ESI-Q-TOF/MS, 1D NMR and 2D NMR. The five known compounds were established by comparing the 1H-NMR and 13C NMR with the reported literature. Oleraciamide D (1) showed cytotoxicity against SH-SY5Y cells when concentration at 50 uM by CCK-8 method. 相似文献
20.
Abdel-Monem AR 《Natural product research》2012,26(3):264-269
A new alkaloid, paradoxonine, and its enol tautomer, paradoxenoline, in addition to a new cembranoid diterpene, paradoxenoic acid, were isolated from the chloroformic fraction of the methanolic extract of Cleome paradoxa B.Br. The structures of the isolated compounds were established based on their spectral data, including MS, (1)HNMR, (13)CNMR, COSY, HMBC and HMQC. This is the first report on the isolation of alkaloids from the family Cleomaceae. 相似文献