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A Novel One‐Pot Method for the Synthesis of Pyrimidine Derivatives Using Ketene N,S‐Acetal with Aryl Aldehydes
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Masayori Hagimori Yuka Murakami Naoko Mizuyama Yoshinori Tominaga 《Journal of heterocyclic chemistry》2016,53(1):197-201
A very simple and facile one‐pot method for the synthesis of pyrimidine derivatives is presented. In this method, 2‐aryl‐pyrimidine derivatives were prepared by the reaction of ketene N,S‐acetal 1 with commercially available aryl aldehydes by heating under solvent and catalyst‐free conditions. The synthesized pyrimidine derivatives showed blue‐green fluorescence in solid state. 相似文献
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