Effect of the particle temperature on lift force of nanoparticle in a shear rarefied flow

The nanoparticles suspended in a shear flow are subjected to a shear lift force, which is of great importance for the nanoparticle transport. In previous theoretical analysis on the shear lift, it is usually assumed that the particle temperature is equal to the temperature of the surrounding gas media. However, in some particular applications, the particle temperature can significantly differ from the gas temperature. In the present study, the effect of particle temperature on the shear lift of nanoparticles is investigated and the corresponding formulas of shear lift force are derived based on the gas kinetic theory. For extremely small nanoparticles(with radius R 2 nm) or large nanoparticles(R 20 nm), the influence of the particle temperature can be neglected. For the intermediate particle size, the relative error induced by the equal gas–particle temperature can be significant. Our findings can bring an insight into accurate evaluation of the nanoparticle transport properties.     

Atomic force microscopy: determination of unbinding force, off rate and energy barrier for protein-ligand interaction

Recently, atomic force microscopy (AFM) based force measurements have been applied biophysically and clinically to the field of molecular recognition as well as to the evaluation of dynamic parameters for various interactions between proteins and ligands in their native environment. The aim of this review is to describe the use of the AFM to measure the forces that control biological interaction, focusing especially on protein-ligand and protein-protein interaction modes. We first considered the measurements of specific and non-specific unbinding forces which together control protein-ligand interactions. As such, we will look at the theoretical background of AFM force measurement curves for evaluating the unbinding forces of protein-ligand complexes. Three AFM model dynamic parameters developed recently for use in protein-ligand interactions are reviewed: (i) unbinding forces, (ii) off rates, and (iii) binding energies. By reviewing the several techniques developed for measuring forces between biological structures and intermolecular forces in the literature, we show that use of an AFM for these applications provides an excellent tool in terms of spatial resolution and lateral resolution, especially for protein-protein and protein-ligand interactions.     

流场环境下复杂囊泡的动力学行为

采用非平衡态分子动力学方法研究了二维复杂囊泡在剪切流中的动力学行为. 模拟发现了复杂囊泡经典的翻滚(tumbling)、摇摆(trembling)和坦克履(tank-treading)行为, 还观察到由坦克履行为向平动行为(translating)的转变. 囊泡的平动行为与剪切率大小、复杂囊泡的形状密切相关. 当大囊泡均匀嫁接较多数目的小囊泡后, 其平动方式消失. 该研究有益于加深对囊泡在剪切流场中复杂性行为的理解.     

Dynamics of viscous vesicles in shear flow

The dynamics of giant lipid vesicles under shear flow is experimentally investigated. Consistent with previous theoretical and numerical studies, two flow regimes are identified depending on the viscosity ratio between the interior and the exterior of the vesicle, and its reduced volume or excess surface. At low viscosity ratios, a tank-treading motion of the membrane takes place, the vesicle assuming a constant orientation with respect to the flow direction. At higher viscosity ratios, a tumbling motion is observed in which the whole vesicle rotates with a periodically modulated velocity. When the shear rate increases, this tumbling motion becomes increasingly sensitive to vesicle deformation due to the elongational component of the flow and significant deviations from simpler models are observed. A good characterization of these various flow regimes is essential for the validation of analytical and numerical models, and to relate microscopic dynamics to macroscopic rheology of suspensions of deformable particles, such as blood.     

Swinging and tumbling of fluid vesicles in shear flow

The dynamics of fluid vesicles in simple shear flow is studied using mesoscale simulations of dynamically triangulated surfaces, as well as a theoretical approach based on two variables: a shape parameter and the inclination angle, which has no adjustable parameters. We show that, between the well-known tank-treading and tumbling states, a new "swinging" state can appear. We predict the dynamic phase diagram as a function of the shear rate, the viscosities of the membrane and the internal fluid, and the reduced vesicle volume. Our results agree well with recent experiments.     

Fluid vesicles with viscous membranes in shear flow

The effect of membrane viscosity on the dynamics of vesicles in shear flow is studied. We present a new simulation technique, which combines three-dimensional multiparticle collision dynamics for the solvent with a dynamically triangulated membrane model. Vesicles are found to transit from steady tank treading to unsteady tumbling motion with increasing membrane viscosity. Depending on the reduced volume and membrane viscosity, shear can induce both discocyte-to-prolate and prolate-to-discocyte transformations. This behavior can be understood from a simplified model.     

均匀流中剪切变形加筋层合板声与振动特性研究

基于一阶剪切变形理论, 建立了分析均匀流中周期加筋层合板声振特性的理论模型. 该模型应用对流波动方程及边界条件精确考虑了均匀流与层合板的耦合作用, 加强筋通过法向线力及扭矩与层合板相互作用, 利用傅里叶波数变换和稳相法, 得到了位移谱和辐射声压的解析表达式. 计算结果与已有公开数据符合良好, 验证了模型的有效性. 数值结果表明, 在高频段不能忽略剪切变形和加强筋扭转运动的影响; 增大均匀流速度可降低结构的辐射声压; 适当调整板厚和加强筋间距可有效避开结构的辐射声压波峰. 关键词： 均匀流 第一阶剪切变形理论 层合板 波数变换     

Vacillating breathing and tumbling of vesicles under shear flow

The dynamics of vesicles under a shear flow are analyzed analytically in the small deformation regime. We derive two coupled nonlinear equations which describe the vesicle orientation in the flow and its shape evolution. A new type of motion is found, namely, a "vacillating-breathing" mode: the vesicle orientation undergoes an oscillation around the flow direction, while the shape executes breathing dynamics. This solution coexists with tumbling. Moreover, we provide an explicit expression for the tumbling threshold. A rheological law for a dilute vesicle suspension is outlined.     

Fluid membranes in hydrodynamic flow fields: Formalism and an application to fluctuating quasispherical vesicles in shear flow

The dynamics of a single fluid bilayer membrane in an external hydrodynamic flow field is considered. The deterministic equation of motion for the configuration is derived taking into account both viscous dissipation in the surrounding liquid and local incompressibility of the membrane. For quasi-spherical vesicles in shear flow, thermal fluctuations can be incorporated in a Langevin-type equation of motion for the deformation amplitudes. The solution to this equation shows an overdamped oscillatory approach to a stationary tanktreading shape. Inclination angle and ellipticity of the contour are determined as a function of excess area and shear rate. Comparisons to numerical results and experiments are discussed. Received 20 August 1998     

Instability of a lamellar phase under shear flow: formation of multilamellar vesicles

The formation of closed-compact multilamellar vesicles (referred to in the literature as the "onion texture") obtained upon shearing lamellar phases is studied using small-angle light scattering and cross-polarized microscopy. By varying the shear rate gamma;, the gap cell D, and the smectic distance d, we show that: (i) the formation of this structure occurs homogeneously in the cell at a well-defined wave vector q(i), via a strain-controlled process, and (ii) the value of q(i) varies as (dgamma;/D)(1/3). These results strongly suggest that formation of multilamellar vesicles may be monitored by an undulation (buckling) instability of the membranes, as expected from theory.     

Electro–magnetic control of shear flow over a cylinder for drag reduction and lift enhancement

In this paper, the electro-magnetic control of a cylinder wake in shear flow is investigated numerically. The effects of the shear rate and Lorentz force on the cylinder wake, the distribution of hydrodynamic force, and the drag/lift phase diagram are discussed in detail. It is revealed that Lorentz force can be classified into the field Lorentz force and the wall Lorentz force and they affect the drag and lift forces independently. The drag/lift phase diagram with a shape of ＂8＂ consists of two closed curves, which correspond to the halves of the shedding cycle dominated by the upper and lower vortices respectively. The free stream shear （K 〉 0） induces the diagram to move downward and leftward, so that the average lift force directs toward the downside. With the upper Lorentz force, the diagram moves downwards and to the right by the field Lorentz force, thus resulting in the drag increase and the lift reduction, whereas it moves upward and to the left by the wall Lorentz force, leading to the drag reduction and the lift increase. Finally the diagram is dominated by the wall Lorentz force, thus moving upward and leftward. Therefore the upper Lorentz force, which enhances the lift force, can be used to overcome the lift loss due to the free stream shear, which is also obtained in the experiment.     

Effects of nonlocal stress on the determination of shear banding flow

We analyze the steady planar shear flow of the modified Johnson-Segalman model, which has an added nonlocal term. We find that the new term allows for unambiguous selection of the stress at which two "phases" coexist, in contrast to the original model. For general differential constitutive models we show the singular nature of stress selection in terms of a saddle connection between fixed points in the equivalent dynamical system. The result means that stress selection is unique under most conditions for space nonlocal models. Finally, illustrated by simple models, we show that stress selection generally depends on the form of the nonlocal terms (weak universality).     

Exact dynamic and static stiffness matrices of shear deformable thin-walled beam-columns

Total potential energy of non-symmetric thin-walled beam-columns in the general form is presented by introducing the displacement field based on semitangential rotations and deriving transformation equations between displacement and force parameters defined at the arbitrary axis and the centroid-shear center axis, respectively. Next, governing equations and force-deformation relations are derived from the total potential energy for a shear-deformable, uniform beam element and a system of linear eigenproblem with non-symmetric matrices is constructed based on 14 displacement parameters. And then explicit expressions for displacement parameters are derived and exact dynamic stiffness matrices are determined using force-deformatin relationships. In addition, the modified numerical method to eliminate multiple zero eigenvalues and to evaluate the exact static stiffness matrix is developed for spatial stability analysis. Finally, in order to demonstrate the validity and the accuracy of this study, the spatially coupled natural frequencies and buckling loads are evaluated and compared with analytical solutions or results analyzed by thin-walled beam elements and ABAQUS's shell elements.     

Radiation force and shear motions in inhomogeneous media

An action of radiation force induced by ultrasonic beam in waterlike media such as biological tissues (where the shear modulus is small as compared to the bulk compressibility) is considered. A new, nondissipative mechanism of generation of shear displacement due to a smooth (nonreflecting) medium inhomogeneity is suggested, and the corresponding medium displacement is evaluated. It is shown that a linear primary acoustic field in nondissipative, isotropic elastic medium cannot excite a nonpotential radiation force and, hence, a shear motion, whereas even smooth inhomogeneity makes this effect possible. An example is considered showing that the generated displacement pulse can be significantly longer than the primary ultrasound pulse. It is noted that, unlike the dissipative effect, the nondissipative action on a localized inhomogeneity (such as a lesion in a tissue) changes its sign along the beam axis, thus stretching or compressing the focus area.     

Elastic capsules in shear flow: Analytical solutions for constant and time-dependent shear rates

We investigate the dynamics of microcapsules in linear shear flow within a reduced model with two degrees of freedom. In previous work for steady shear flow, the dynamic phases of this model, i.e. swinging, tumbling and intermittent behaviour, have been identified using numerical methods. In this paper, we integrate the equations of motion in the quasi-spherical limit analytically for time-constant and time-dependent shear flow using matched asymptotic expansions. Using this method, we find analytical expressions for the mean tumbling rate in general time-dependent shear flow. The capsule dynamics is studied in more detail when the inverse shear rate is harmonically modulated around a constant mean value for which a dynamic phase diagram is constructed. By a judicious choice of both modulation frequency and phase, tumbling motion can be induced even if the mean shear rate corresponds to the swinging regime. We derive expressions for the amplitude and width of the resonance peaks as a function of the modulation frequency.     

Free vibration and parametric resonance of shear deformable functionally graded cylindrical panels

This paper investigates free vibration and dynamic instability of functionally graded cylindrical panels subjected to combined static and periodic axial forces and in thermal environment. Theoretical formulations are based on Reddy's higher order shear deformation shell theory to account for rotary inertia and the parabolic distribution of the transverse shear strains through the panel thickness. Thermal effects due to steady temperature change are included in the analysis. Material properties are assumed to be temperature dependent and graded in the thickness direction according to a power-law distribution in terms of the volume fractions of the constituents. The panel under current consideration is clamped or simply supported on two straight edges and may be either free, simply supported or clamped on the curved edges. A semi-analytical approach, which takes the advantages of one-dimensional differential quadrature approximation, Galerkin technique and Bolotin's method, is employed to determine the natural frequencies and the unstable regions of the panel. Numerical results for silicon nitride/stainless-steel cylindrical panels are given in both dimensionless tabular and graphical forms. Effects of material composition, temperature rise, panel geometry parameters, and boundary conditions on free vibration and the parametric resonance are also studied.     

Shape diagram of vesicles in Poiseuille flow

Soft bodies flowing in a channel often exhibit parachutelike shapes usually attributed to an increase of hydrodynamic constraint (viscous stress and/or confinement). We show that the presence of a fluid membrane leads to the reverse phenomenon and build a phase diagram of shapes-which are classified as bullet, croissant, and parachute-in channels of varying aspect ratio. Unexpectedly, shapes are relatively wider in the narrowest direction of the channel. We highlight the role of flow patterns on the membrane in this response to the asymmetry of stress distribution.     

Vibration analysis of nanorings using nonlocal continuum mechanics and shear deformable ring theory

In this article, we use shear deformable ring theory (SDRT) for the analysis of free in-plane vibration of nanorings based on nonlocal elasticity theory. The equations of motion of the nanoring are derived for the aforementioned problem by considering the small scale effect. Analytical solutions for the natural frequencies of the nanorings are presented. It is shown that the nonlocal effects play an important role in the vibration of nanorings and cannot be neglected. The effects of the small scale on the natural frequencies considering various parameters such as the radius of the nanoring, the thickness of the nanoring and mode numbers are investigated.