The iron(III) complexes [Fe(2Am4DH)2]Cl (1), [Fe(2Am4Me)2]Cl (2) and [Fe(2Am4Et)2]Cl (3) with 2-pyridineformamide thiosemicarbazone (H2Am4DH) and its N(4)-methyl (H2Am4Me) and N(4)-ethyl (H2Am4Et) derivatives were obtained and characterized by means microanalyses, infrared and EPR spectra. The electrochemical behavior of the complexes was investigated. The thiosemicarbazones and complexes (1) and (2) presented toxicity against Artemia salina at low concentrations. Since this bioassay has a good correlation with cytotoxic activity in human solid tumors, the studied compounds present potential pharmacological applications. 相似文献
The extraction of Am(III) from nitric, hydrochloric, oxalic, phosphoric and hydrofluoric acids was studied using 0.4F di-2-ethyl hexyl phosphoric acid (HDEHP) containing 0.1M phosphorous pentoxide (P2O5) in dodecane/xylene. The extraction with pure 0.4F HDEHP was found to be negligible from all the media studied. However, the presence of a small amount of P2O5 in it increased the extraction substantially. The distribution ratios of Am(III) obtained for HDEHP - P2O5 mixture 3M nitric acid containing different concentrations of oxalic acid/phosphoric acid/hydrofluoric acid are in the order of 200-250. The same for 3M hydrochloric acid is very high (800). These distribution ratios are sufficiently high for the quantitative extraction of Am(III) from all the acid media studied. Different reagents such as ammonium oxalate, sodium oxalate, oxalic acid, hydrofluoric acid, sodium carbonate and potassium sulphate were explored for the back extraction of Am(III) from 0.4F HDEHP + 0.1M P2O5 in dodecane/xylene. Of these, 0.35M ammonium oxalate and 1M sodium carbonate were found to be most suitable. The back extraction of Am(III) was also attempted with water and 1M H2SO4, HNO3, HClO4 and HCl solutions after allowing the extracted organics to degrade on its own. It was found that more than 90% of Am could be back extracted with these acids. Using this method more than 90% of Am(III) was recovered from nitric acid solutions containing calcium and fluoride ions. 相似文献
A series of tests were performed using centrifugal contactors to evaluate the separation of Am(VI) from cerium, as well as to determine the efficiency of the contactors. All experiments were performed using 2-cm, acrylic 3D-printed centrifugal contactors. Solvent extraction tests were performed using 1 M N,N-di(2-ethylhexyl)butyramide (DEHBA)/dodecane and a nitric acid feed solution spiked with 243Am and 139Ce and oxidized with 60 mg mL?1 sodium bismuthate. Approximately 72% of the Am was extracted with a single contactor stage. Co-stripping of Am and Ce was demonstrated but attempts at selective stripping were not successful. Successful recycle of the used organic phase was demonstrated. Contactor efficiencies of 95–100% were obtained. 相似文献
Age of individual uranium–plutonium (U/Pu) mixed particles with various U/Pu atomic ratios (1–70) were determined by inductively coupled plasma mass spectrometry. Micron-sized particles were prepared from U and Pu certified reference materials. The Pu reference was stored for 4–6 years since the last purification (July 14, 2008). The Pu purification age was obtained from the 241Am/241Pu ratio which was calculated from the product of three measured ratios of Pu and Am isotopes in the eluted fractions. These ratios were measured by a high-resolution inductively coupled plasma mass spectrometer equipped with a desolvation system. Femto-gram to pico-gram quantities of Am, U, and Pu in a sample solution were sequentially separated on a small anion-exchange column. The 241Am/241Pu ratio was accurately determined by spiking pure 243Am into the sample solution. The average determined age for the particles for the five independent U/Pu ratios was in good agreement with the expected age with high accuracy (difference age 0.27 years) and high precision (standard deviation 0.44 years). The described analytical technique can serve as an effective tool for nuclear safeguards and environmental radiochemistry.
Figure Young (4?6 y) Pu purification age of individual U/Pu mixed micron-sized reference particles for the five independent U/Pu ratios (1?70) were determined with 0.27±0.44 y difference from the expected age. Sub pico-gram quantities of Am, U and Pu were sequentially separated a small column, and their isotope ratios were accurately measured using an ICP-MS by applying the 243Am spiking technique to the analysis and correcting the impurity and the contaminations.
A system using an ion chromatograph coupled to a flow-cell scintillation detector for rapidly measuring the oxidation states of actinides at low concentrations (<10–6M) in aqueous solutions was evaluated. The key components of the system are a cation–anion separation column (Dionex, CS5) and a flow cell detector with scintillating cerium activated glass beads. The typical procedure was to introduce a 0.5 ml aliquot of sample spiked with actinides in the +III to +VI oxidation states into a 5 ml sample loop followed by 4 ml of synthetic groundwater simulant. Separation was achieved at a flow rate of 1 ml/min using an isocratic elution with oxalic, diglycolic, and nitric acids followed by distilled water. Tests were first conducted to determine elution times and recoveries for an acidic solution (pH 2) and a ground water simulant (pH 8) containing Am(III), Pu(IV), Th(IV), Pu(V), and U(VI). Then, an analysis was performed using a mixture of Pu(IV), Pu(V), and Pu(VI) in the ground water simulant and compared to results using the DBM extraction technique. Approximate elution times were the same for both the acidic solution and the ground water simulant. These were as follows: Pu(V) at 10 min, Am(III) at 15 min, Pu(IV) at 25 min, Th (IV) at 28 min and U(VI) at 36 min. Recoveries for the acidic solution were quantitative for U(VI) and Th(IV) and exceeded 80% for Am(III). Recoveries for the ground water simulant were quantitative for U(VI), but they were generally not quantitative for Th(IV), Pu(IV), and Am(III). For Th(IV) and Pu(IV), less than quantitative recoveries were attributed to the formation of neutral hydroxides and colloids; for Am(III) they were attributed to insoluble carbonates and/or hydroxycarbonates. When applied to the measurement of plutonium in the ground water simulant, the technique provided showed good agreement with the dibenzoylmethane (DBM) extraction technique, but it could not distinguish between Pu(V) and Pu(VI). This was likely due to the reduction of Pu(VI) to Pu(V) in the sample by the oxalic acid eluent. However, in spite of this limitation, the technique can be used to distinguish between Pu(IV) and Pu(V) in aqueous environmental samples within a pH range of 4 to 8 and an EH range of -0.2 to 0.6 V, the predominance region for Pu(III), (IV), and (V). In addition, this technique can be used to corroborate oxidation state analysis from the dibenzoylmethane (DBM) extraction method for environmental samples. 相似文献
A novel method for the efficient discovery of new types of minor actinide (MA) ligands is based on the unique combination of "tea bag" split pool combinatorial chemistry and screening based on the inherent radioactivity of the complexed cations. Four multicoordinating Am(3+) chelating groups, such as CMPO (diphenylcarbamoylmethyl)phosphine oxide), PICO (picolinamide), DGA (N,N'-dimethyldiglycoldiamide), and MPMA (N-methyl-N-phenylmalonamide), on a trityl platform immobilized on TentaGelS served as a model library for the development of the screening method. This model library was screened under various conditions (i.e., 0.001 M < or = [HNO3] < or = 3 M, NaNO3 < or = 4 M, and [Eu] < or = 10 x [ligand]) showing competitive extraction of the four ligands. Other libraries of 9 and 72 members were synthesized by functionalization of the trityl platform with ligating groups that are composed of four building blocks (including at least one amide and one (phosphoric) hydrazone moiety). The screening of these two libraries resulted in the discovery of two multicoordinate ligands that contain ligating groups previously not known to complex Am(3+). Both are N-isopropyl amides terminated with a p-methoxyphenyl hydrazide (A2B1C1D10 K(D(Am)) = 2197) or a p-nitrophenyl hydrazide (A2B1C1D11 K(D(Am)) =1989) moiety, respectively. They are more efficient than the immobilized tritylCMPO ligand (K(D(Am)) = 1280) at 3 M HNO3. This method has the advantages of a high analytical sensitivity and the direct comparison of the extraction results. The method also allows the competitive screening of multiple nuclides which can be quantified by their radioactive emission spectrum. 相似文献
A method was developed for isolating neptunium from Pu, U or mixed oxide (MOX) samples and its determination by isotope dilution -spectrometry (IDGS) using239Np (243Am) as a spike. Extraction chromatography with trilaurylamine fixed on a SGX-C18 support was used for the isolation of Np. The decontamination factors for U, Pu, Am and Pa vary between 1000–2000 and 100, respectively. The average separation yield of Np is (95±3)%. The amount of243Am required for spiking is about 0.2–0.3 g. It is recommended to use the pair of -rays 86.53 keV (237Np)-106.13 keV (239Np) for the assay of neptunium. A relative uncertainty of 4% or better is achievable in the analysis of plutonium samples, containing 0.4–80 g neptunium. The detection limit, under the proposed experimental conditions, is about 0.05 g Np. The results were compared with the results obtained by using high resolution -spectrometry (HRGS). 相似文献
Extraction of Am(III) by dihexyl N,N-diethylcarbamoylmethyl phosphonate (CMP) in benzene from nitric acid solutions (pH 2.0 to 6.0M) has been studied. High extraction of Am(III) by CMP from 2–3M HNO3 was observed. The species extracted was found to be Am(NO3)3·3CMP. The extraction was also done with mixtures of CMP+TBP and CMP+TOPO, where mixed species were extracted in the organic phase. The back-extraction experiments gave an efficient back-extraction of Am(III) by pH 2.0 (HNO3) from the loaded CMP+TBP phase but a poor back-extraction from the loaded CMP+TOPO phase. The loading of Nd(III) by mixture of CMP and TBP was 50% of the CMP concentrations at a total Nd(III) concentration of 0.182M. The thermodynamic parameters of Am(III) extraction by a mixture of CMP and TBP were evaluated by temperature variation method, which suggests that the two-phase reaction is stabilized by enthalpy and opposed by entropy. 相似文献
The binary systems of iron(II) and iron(III) with 2-pyridineformamide thiosemicarbazone (H2Am4DH) and its N(4)-methyl (H2Am4Me), N(4)-ethyl (H2Am4Et) and N(4)-phenyl (H2Am4Ph) derivatives were studied in aqueous solution by pH-potentiometry, ultraviolet–visible spectroscopy and EPR spectra. The formation constants of the iron(II) and iron(III) complexes were calculated from potentiometric and electronic absorption data at 25 °C and ionic strength μ = 0.1 mol·L?1 using the HYPERQUAD program. The values of the formation constant of the FeL species decrease in the order Fe:H2Am4DH > Fe:H2Am4Me ≈ Fe:H2Am4Et > Fe:H2Am4Ph in the same way as the basicity of the ligands. The species distribution diagrams show that the species FeL2 predominates at physiological pH in the Fe:H2Am4DH, Fe:H2Am4Me and Fe:H2Am4Et systems. The similar EPR spectra of these iron(III) binary systems indicate the same coordination spheres around the metallic center and the EPR g values suggests that the unpaired electron is in the dxy orbital, indicating a dxz2dyz2dxy1 ground state configuration for the complexes. For the Fe(III):H2Am4Ph system the EPR results indicated dimerization and antiferromagnetic interaction due to the presence of only one thiosemicarbazone ligand around the metallic center. 相似文献