复发性阿弗他溃疡与相关的营养因素研究进展

以国内外研究复发性阿弗他溃疡营养因素的相关论文为依据,综述了近十年有关对复发性阿弗他溃疡（RAU）营养因素的研究进展。包括：RAU与微量元素锌、铁、硒、铜,维生素A、C、E、B2、B12,蛋白质,膳食纤维和谷类的关系。RAU的发生与体内微量元素锌、铁、硒、铜的减少,维生素A、C、E、B2、B12,蛋白质和膳食纤维的摄取不足密切相关,全谷类食品（功能稻米）对缓解RAU有帮助。     

广州市631名大学生复发性阿弗他溃疡的发病调查

为制订干预措施,控制和降低RAU的发病率,利用白编的《复发性阿弗他溃疡调查表》,对631名在校学生进行了问卷调查。结果表明,631人中有375人患复发性阿弗他溃疡,患病率为59．43％,其中频发为8．56％,偶发为50．87％,患病学生中伴有消化道症状的有47．46％,几乎每个患病学生都认为复发性阿弗他溃疡的发病都与饮食有关。提示广州市在校医学生复发性阿弗他溃疡的发生率与饮食等因素密切相关,开展饮食干预有很大的需求基础。     

多甙颗粒剂对阿弗他溃疡患者红细胞免疫功能的调节作用

为观察多甙颗粒剂对复发性阿弗他溃疡患者治疗前后红细胞免疫功能和血清中CR1免疫调节因子活性的调节作用,采用红细胞-酵母免疫黏附法测定了235例复发性阿弗他溃疡患者RBC-c3bRR及血清中CR1免疫调节因子。结果表明,红细胞RBC-c3b受体花环率与对照组比较,组1有显著差异(P<0.01),组1与组2 RBC-c3b受体花环率对比有显著差异(P<0.01),红细胞免疫复合物花环率与对照组相比,两组均显著增高(P<0.01),CR1免疫黏附促进因子活性与对照组相比,组1组2均显著降低(P<0.01),CR1免疫黏附抑制因子活性与对照组相比,两组均增高(P<0.01)。提示复发性阿弗他溃疡患者存在红细胞免疫功能受损,多甙颗粒剂对复发性阿弗他溃疡患者的红细胞免疫功能有调节作用。     

国内外功能性稻米研究进展

以国内外研究功能性稻米对人体生理功能和潜在对复发性阿弗他溃疡影响的代表性论文为依据,综述了近年来有关功能性稻米对人体生理功能和对复发性阿弗他溃疡潜在影响的研究进展,包括:功能性稻米的定义、分类,国内外研究进展以及具有多种有生理作用的功能因子(铁、硒、γ-氨基丁酸、膳食纤维、抗性淀粉、黄酮和脂肪酸、花色苷类化合物),这些功能因子对人体多个系统有调节作用,对缓解复发性阿弗他溃疡的症状,减少其发生起着重要的作用。     

本刊两论文获2009年全国大学生挑战杯奖

由广州医学院刘婷、吕晨、冯晓蕾、蔡巧丽、谢利平、翁志强（指导老师）等撰写的“复发性阿弗他溃疡与相关营养因素研究进展”（广东微量元素科学，2009，16（3）：1-10）和由谢利平、叶决新、蔡巧丽、刘婷、刘亮、石宇文、翁志强（指导老师）等撰写的“广州市631名大学生复发性阿弗他溃疡的发病调查”（广东微量元素科学，2009，16（6）：12—15）”两篇论文，荣获2009年全国大学生挑战杯课外科技比赛广东省赛区三等奖。     

The Evaluation of Healing Properties of Galium verum-Based Oral Gel in Aphthous Stomatitis in Rats

Although oral ulcers represent one of the most frequent oral mucosal diseases, the available treatment is not sufficient to provide complete ulcer recovery without side-effects. Therefore, the aim of our study was to prepare a mucoadhesive oral gel based on Galium verum ethanol extract (GVL gel) and reveal its healing effects in the model of aphthous stomatitis in rats. Rats with oral ulcers were divided into the following groups: control (untreated), gel base (ulcer was treated with the gel base, three times per day for 10 days), and GVL gel group (the ulcer was treated with GVL gel in the same way as the gel base). Animals from each group were sacrificed on days 0, 3, 6, and 10 for collecting blood and ulcer tissue samples. Healing properties of oral gel were determined by clinical evaluation, as well as biochemical and histopathological examinations. Our findings suggest a significant decrease in the ulcer size in GVL gel group, with healing effects achieved through the alleviation of oxidative stress, reduction in COX-2 immunopositivity, and increase in collagen content in buccal tissue. Significant ulcer repairing potential of GVL gel highlights this oral mucoadhesive gel as a promising tool for prevention and treatment of RAS.     

儿童复发性口腔溃疡血清微量元素的分析

目的探讨了儿童复发性口腔溃疡血清微量元素的变化。方法分别收集实验组和对照组静脉血清样品各50例,应用等离子体发射光谱仪测定Zn、Cu、Fe、Mg含量。结果儿童血清微量元素含量测定,实验组Zn含量明显低于对照组（P〈0.05）,Cu、Fe、Mg含量与对照组比无显著性差异（P〉0.05）。结论儿童复发性口腔溃疡的发生与体内缺Zn有关,值得进一步探讨。     

Genesis and Mechanism of Some Cancer Types and an Overview on the Role of Diet and Nutrition in Cancer Prevention

Cancer is a major disease with a high mortality rate worldwide. In many countries, cancer is considered to be the second most common cause of death after cardiovascular disease. The clinical management of cancer continues to be a challenge as conventional treatments, such as chemotherapy and radiation therapy, have limitations due to their toxicity profiles. Unhealthy lifestyle and poor dietary habits are the key risk factors for cancer; having a healthy diet and lifestyle may minimize the risk. Epidemiological studies have shown that a high fruit and vegetable intake in our regular diet can effectively reduce the risk of developing certain types of cancers due to the high contents of antioxidants and phytochemicals. In vitro and in vivo studies have shown that phytochemicals exert significant anticancer effects due to their free radical scavenging capacity potential. There has been extensive research on the protective effects of phytochemicals in different types of cancers. This review attempts to give an overview of the etiology of different types of cancers and assesses the role of phytonutrients in the prevention of cancers, which makes the present review distinct from the others available.     

中西医结合治疗复发性口疮102例疗效观察

用参麦汤合葡萄糖酸锌片治疗复发性口疮１０２例，经过３个月治疗，观察到该药能有效地改善临床症状，降低复发率，明显地提高体内锌的水平，与维生素类对照组比较，疗效有显著性差异（Ｐ＜０．０１）。     

小剂量雷公藤多甙治疗复发性口疮对血清微量元素影响的研究

为探讨复发性口疮患者血清微量元素的改变及小剂量雷公藤多甙对患者血清微量元素的影响，选择了复发性口疮患者１４３例对观察组Ⅰ，予以小剂量雷公藤多甙、复方丹参、锌铁制剂口服。观察组Ⅱ，１１０例，只接受复方丹参，锌铁制剂治疗。测定了服药前、服药２个月后及停药３个月后血清Ｚｎ、Ｃｕ、Ｆｅ含量及Ｃｕ／Ｚｎ比值，对照组为正常体检健康人员１００例。结果表明：（１）治疗前实验组Ⅰ、Ⅱ对照组比较，Ｚｎ、Ｆｅ含量下降，     

原子吸收法分析中成药中的无机微量元素

分别采用火焰原子吸收法和石墨炉原子吸收法分析了江西省产12种中成药中22种无机微量元素的含量，并对所含的无机微量元素及其效用进行了初探，说明了中成药的功效与其所含的无机微量元素有一定联系。