LIMS系统在实验室规范运作中的应用

简要介绍了LIMS系统及其对规范实验室运作发挥的作用和在应用中的具体情况。     

The impact of LIMS design and functionality on laboratory quality achievements

 A laboratory information management system (LIMS) can make a major contribution to the quality and therefore to the efficiency and competitiveness of a laboratory. Since it can impact all aspects of a laboratory's organization it must be the key if not the principal player of the laboratory's quality system. It should support the laboratory in establishing, maintaining and applying quality procedures thereby enabling the laboratory to achieve its quality goals. As a tool, LIMS permits the laboratory to input and use its own know-how and experience to optimize the total organization (internal and external) and workflow of generated information. However, perceived "quality" in the context of an LIMS, can be viewed as being made up of different facets such as the security, reliability and accessibility of information as well as its turn around time and production cost. This paper reviews the role of a LIMS in the laboratory and the contribution that both system design and functionality can have on "building quality ". Received: 5 October 1998 · Accepted: 20 October 1998     

实验室信息管理系统研究与开发

给出了实验室信息管理系统的研究思路和开发方法,介绍了此系统的主要模块的功能和特点。     

Microanalysis of geological samples by laser plasma ionization mass spectrometry (LIMS)

Laser plasma ionization mass spectrometry (LIMS) has been applied for in-situ microanalysis of minerals and inclusions in geo- and cosmochemical samples down to the ng/g concentration level. A great advantage of this method is that at high laser power densities (2×10¹⁰ W/cm²) used, most elements are ionized with about the same efficiency independent of chemistry and mineralogy of the samples. A procedure has been developed which allows quantitative analysis of about 30 trace elements with an accuracy of better than 25%.     

Bar code sample identification: the key to laboratory information management systems (LIMS) productivity

Laboratory information management systems (LIMS) are becoming increasingly sophisticated. The value of the LIMS is directly related to its accuracy (can these test results be trusted, verified, repeated?) and to its efficiency (how rapidly can the system operate?). LIMS is essentially a productivity tool that involves some of the most complex software in existence.While automated testing has been expanding in sophistication, the systems are often impeded by outmoded data collection techniques. Any system is only as good as its weakest link, and as fast as its slowest link. Increasing the speed of each testing step in the laboratory will produce only marginal productivity improvements. The key to increased LIMS productivity is the speed and accuracy of the data collection techniques. A fast and accurate method of automated data collection is bar coding scanning.     

Trace element analysis of geological glasses by laser plasma ionization mass spectrometry (LIMS): A comparison with other multielement and microanalytical methods

Laser plasma ionization mass spectrometry (LIMS) is used in our laboratory as an in-situ microanalytical method for the investigation of solids, especially of rocks and minerals. To demonstrate the accuracy of this method we have analyzed homogeneous geological glass samples. The results are compared with data obtained from other analytical techniques. The performance of the LIMS method for geochemical investigations is discussed. Received: 2 December 1996 / Revised: 21 February 1997 / Accepted: 26 February 1997     

Facilitating quality control for spectra assignments of small organic molecules: nmrshiftdb2 – a free in‐house NMR database with integrated LIMS for academic service laboratories

nmrshiftdb2 supports with its laboratory information management system the integration of an electronic lab administration and management into academic NMR facilities. Also, it offers the setup of a local database, while full access to nmrshiftdb2's World Wide Web database is granted. This freely available system allows on the one hand the submission of orders for measurement, transfers recorded data automatically or manually, and enables download of spectra via web interface, as well as the integrated access to prediction, search, and assignment tools of the NMR database for lab users. On the other hand, for the staff and lab administration, flow of all orders can be supervised; administrative tools also include user and hardware management, a statistic functionality for accounting purposes, and a ‘QuickCheck’ function for assignment control, to facilitate quality control of assignments submitted to the (local) database. Laboratory information management system and database are based on a web interface as front end and are therefore independent of the operating system in use. Copyright © 2015 John Wiley & Sons, Ltd.