New Chemical Compound from Caraganajubata （pall.） Poir.

<正>A new pterocarpan glycoside,(-)-maackiain 3-O-6'-O-acrylyl-β-D-galactopyranoside(1) was isolated from the whole parts of Caragana jubata(pall.) Poir.,together with three known pterocarpan glycosides,(-)-maackiain 3-O-6'-O-acetyl-β-D-glucopyranoside(2),(-)-maackiain 3-O-β-D-glucopyranoside(3) and(-)-maackiain 3-O-β-D-galactopyranoside(4).All the compounds were isolated from the title plant for the first time.The structure of the new compound was established on the basis of detailed 1D,2D NMR and circular dichroism spectroscopic analyses.All the compounds were evaluated for their cytotoxic activities against three tumor cell lines,A549,HL-60 and P388.     

A NEW TRITERPENE GLYCOSIDE FROM THE ROOT OF ASTER TATARICUS L. F

A new oleanane-rype triterpene glycoside, Aster saponin G, was isolated from the root of Aster tataricus L.F. (Compositae). and its structure was elucidated on the basis of spectral and chemical methods. Aster saponin G is 3-0[α-L-arabinopyranosyl-(1→6)-β-D-glucopyranosyl]-2β,3β, 16α-trihydroxyolean-12-en-28-oic acid(asterogenic acid) 28-0-[β-D-xylopyranosyl-(1→4)-α-L-rhamnopyranosyl-(1→2)-β-D-xylopyranosyl] ester     

A New 10—Hydroxyl Anthrone Glycoside from Cassia Siamea Lam.

A new 10-hydroxyl anthrone glycoside,1,8,10-trihydroxyl-1-O-β-D-glucopyranosyl-3-methyl-10-C(S)-β-D-glucopyranosyl-anthrone-9 1 was isolated from the stem of Cassia siamea Lam. The structure was elucidated by spectral evidences, especially by 2D techniques.     

A New Bisxanthone from Hypericumjaponicum Thunb. ex Murray

A new bisxanthone, named bijaponicaxanthone C, was isolated from the whole plant of Hypericum japonicum. The structure was elucidated as 6-[1″,5″,6″-trihydroxy-2″′-(β-hydroxy-β-methylethyl)-2″′,3″′dihydrofuran(5″′,4″′，3″′,4″′)xanthone-3″′-oxyl]- 1,3,5-trihydroxy-4-isoprenylxant-hone (1) on the basis of the spectral and chemical evidences.     

Septemloside III： A Nonasaccharide Saponin from the Bark of Kalopanax septemlobus （Thunb.） Koidz.

A nonasaccharide saponin, new hederagenin saponin, had been isolated from the bark ofKalopanax septemlobus (Thunb.) Koidz., and its structure was elucidated by HRESI-MS, NMR experi-ments and chemical analyses as 3-O-β-D-xylopyranosyl-(1→4)-13-D-xylopyranosyl-(1→3)-α-L-rhamno-pyranosyl-(1→2)-α-L-arabinopyranosyl hederagenin 28-O-β-D-xylopyranosyl-(1→3)-β-D-xylopyra-nosyl-(1→2)-[α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranosyl-(1→6)]-β-D-glucopyranoside.     

A New Diterpenoid Glucoside from Aster smithianus

A new diterpenoid trisaccharide, smithoside A, was isolated from Aster smithianus. Its structure was identified as pimar- 15 (16)-β-en-3β, 8β, 11α-triol-3-O-β-D-glucopyranosyl ( 1→3)- [β-glucopyranosyl (1→2)]-β-D-glucopyranoside on the basis of the spectral and chemical methods.     

A New Degraded Sesquiterpene from Marine Actinomycete Streptomyces sp. 0616208

A new degraded sesquiterpene was isolated from the marine actinomycete Streptomyces sp. 0616208. Its structure was elucidated as (1α,4aα,5α, 7β, 8aβ)-5, 8a-dimethyl-decahydronaphthalene -1, 4a, 7-triol on the basis of spectroscopic data.     

A new panaxadiol from the acid hydrolysate of Panax ginseng

A new panaxadiol(compound 1) was obtained from the acid hydrolysate of the total ginsenosides of Panax ginseng C.A.Meyer (Araliaceae).On the basis of spectroscopic data and single-crystal X-ray diffraction data,its chemical structure was elucidated to be dammar-(E)-20(22)-ene-3β,12β,25-triol.     

A New Asterosaponin from the Starfish Culcita novaeguineae

A new asterosaponin named novaeguinoside A, along with a known saponin, asteronyl pentaglycoside sulfate, was isolated from the starfish Culcita novaeguineae. The new compound was identitied to be sodium 6α-O-{β-D-fucopyranosyl-(1→2)-β-D-fucopyranosyl-(1→4)-[β-D-quinovopyranosyl-(1→2)]-β-D-xylopyranosyl-(1→3)-[β-D-quinovopyranosyl}-5α-pregn-9(11)-en-20-one-3β-yl-sulfate by extensive spectral analysis and chemical evidence.     

Segetoside L, A New Triterpenoid Saponin from Vaccaria segetalis

A new triterpenoid saponin, named segetoside L, was isolated from the seeds of Vaccaria segetalis. On the basis of spectral data and chemical reaction, its structure was established as 28-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl oleanolic acid 3-O-β-D-glucopyranosyl-(1→3)- [β-D-galactopyranosyl-(1→2)]-β-D-galactopyranoside.     

海枫藤中C21甾体苷的分离和结构测定

从萝摩科植物海枫藤[Marsdenia officinalis Tsiang et P.T.Li.]的藤茎中分离得到四个C21甾体去氧糖苷(1)～(4). 通过化学降解和波谱技术, 确定它们的化学结构依次为: 12-O-桂皮酰基-20-O-乙酰基(20S)-孕甾烷-6-烯-3β,5α,8β,12β,14β, 17β,20-庚醇 3-O-甲基-6-去氧-β-D-阿洛吡喃糖基-(1→4)-β-D-夹竹桃吡喃糖基-(1→4)-β-D-磁麻吡喃糖苷(1), 12-O-桂皮酰基-20-O-乙酰基(20S)-孕甾烷-6-烯-3β,5α,8β,12β,14β,17β,20-庚醇3-O-β-D-葡萄吡喃糖基-(1→4)-3-O-甲基-6-去氧-β-D-阿洛吡喃糖基-(1→4)-β-D-磁麻吡喃糖基-(1→4)-β-D-磁麻吡喃糖苷(2), 12-O-桂皮酰基-20-O-乙酰基(20S)-孕甾烷-6- 烯-3β,5α,8β,12β,14β,17β,20-庚醇3-O-β-D-黄夹吡喃糖基-(1→4)-β-D-磁麻吡喃糖基-(1→4)-β-D-磁麻吡喃糖苷(3), 12-O-烟酰基-肉珊瑚苷元3-O-β-D-葡萄吡喃糖基-(1→4)-3-O-甲基-6-去氧-β-D-阿洛吡喃糖基-(1→4)-β-D-夹竹桃吡喃糖基- (1→4)-β-D-磁麻吡喃糖基-(1→4)-β-D-磁麻吡喃糖苷(4). 其中1和2为新化合物, 分别命名为haifengtenoside A, haifengtenoside B, 3和4分别为已知化合物mucronatoside H 和 hainaneosides A, 系首次从该植物中分离得到.     

Triterpene glycosides ofAstragalus and their genins. VII. Structures of cyclosieversiosides A and C

Two new glycosides, cyclosieversiosides A and C, have been isolated from the roots ofAstragalus sieversianus Pall.Cyclosieversioside A is cyclosieversigenin 3-0-(2′,3′-di-0-acetyl-β-D-xylopyranoside) 6-0-β-D-xylopyranoside. Cyclosieversioside C is cyclosieversigenin 3-0-(2′-0-acetyl-β-D-xylopyranoside) 6-0-β-D-xylopyranoside.     

黄褐毛忍冬中主皂苷成分的结构解析

报道了黄褐毛忍冬中的两个皂苷主成分, 其中化合物1为新化合物, 并对另一个含量最高的皂苷结构进行了修正.     

云南重楼中的新甾体皂苷

从云南重楼Paris polyphylla Sm. var. yunnanensis(France. )Hand.-Mazz.的干燥根茎中分离鉴定了4个甾体皂苷(1~4), 其中化合物1是新化合物, 采用波谱技术鉴定其结构为24-O-β-D-吡喃半乳糖基-(23S,24S)-螺甾-5, 25(27)-二烯-1β,3β,23,24-四醇-1-O-β-D-吡喃木糖基(1→6)-β-D-吡喃葡萄糖基(1→3)[α-L-吡喃鼠李糖基(1→2)]-β-D-吡喃葡萄糖苷.     

Glycosides of marine invertebrates. XII. Structure of a new triterpene oligoglycoside from holothurians of familyStichopodidae

From an ethanolic extract of the holothuriansStichopus chloronotus by column chromatography on silica gel a new triterpene oligoside has been isolated the structure of which has been established as 23(S)-acetoxy-3β-{4′-O-[O-(3-O-methyl-β-D-glucopyranosyl)-(1→3)-β-D-glucopyranosyl]-2′-O-[O-(3-O-methyl-β-D-glucopyranosyl(-(1→3)-O-β-D-xylopyranosyl-(1→4)-β-D-glucopyranosyl]-β-D-xylopyranosyloxy}holost-7-ene. A hypothesis has been put forward concerning the biosynthesis of the carbohydrate chains in the glycosides of holothurians of the orderAspidochirota from bioside blocks.     

Steroid saponins and sapogenins ofAllium. XV. Eruboside B fromAllium erubescens

A new steroid glycoside of the spirostan series — eruboside B (I) — has been isolated from an ethanolic extract of the bulbs ofAllium erubescens C. Koh. In an acid hydrolysate, the aglycone β-chlorogenin (II) and the sugars D-glucose and D-galactose in a ratio of 3:1 have been found. By methylation, partial hydrolysis, and oxidation the structure of the spirostanol (I) has been established as (25R)-5α-spirostan-3β,6β-diol 3-O-{[O-β-D-glucopyranosyl-(1→3)]-[O-β-D-glucopyranosyl-(1→2)]-O-β-D-glucopyranosyl-(1→4)-β-D-galactopyranoside}.     

黑鳗藤中C_(21)甾体苷的分离和结构测定

从萝藦科植物黑鳗藤[Stephanotis mucronta (Blanco) Merr.]的藤茎中分离 到三个C_(21)甾体去氧糖苷（1） - （3）。通过化学降解和波谱技术，确定它们 的化学结构依次为：12-O-惕各酰基-20-O-乙酰基肉珊瑚苷元3-O-β-黄夹吡喃糖基 -（1→4）-β-磁麻吡喃糖基-（1→4）-β-磁麻吡喃糖苷（1），5，6-双氢-12-O- 乙酰基-20-O-惕各酰基肉珊瑚苷元3-O-β-黄夹吡喃糖基-（1→4）-β-磁麻吡喃糖 基-（1→4）-β-磁麻吡喃糖基（2）；12-O-乙酰基-20-O（N-甲基）邻氨基苯甲酰 基肉珊瑚甘元3-O-β-黄夹吡喃糖基-（1→4）-β-磁麻吡喃糖基-（1→4）-β-磁 麻吡喃糖甘（3）。其中1和2为新化合物，分别命名为mucronatoside A， mucrontoside B。3为已知化合物stephanoside E，系首次从该植物中分离得到。     

Steroid glycosides ofNicotiana tabacum seeds I. The structures of nicotianosides A,B, and E

Two steroid glycosides of the spirostan series — nicotianosides A and B — and one glycoside of the furostan series — nicotianoside E — have been isolated from the seeds ofNicotiana tabacum L. Nicotianoside A is (25S)-5α-spirostan-3β-ol 3-O-β-D-glucopyranoside, nicotianoside B is (25S)-5β-spirostan-3β-ol 3-O-[O-α-L-rhamnopyranosyl-(1→2)-gb-D-glucopyranoside], and nicotianoside E is (25S)-5α-furostan-3β,22α,26-triol 26-O-β-glucopyranoside 3-O-[O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside].     

Triterpene glycosides ofAstragalus and their genins. XXII. Cycloorbicoside A fromAstragalus orbiculatus

The quantitatively main glycoside — cycloorbicoside A — has been isolated from the epigeal parts of the plantAstragalus orbiculatus, and on the basis of chemical transformations and spectral characteristics its structure has been established as (23R,24S)-16β,23:16α,24-diepoxycycloartane-3β,7β,25-triol 3-0-β-D-xylopyranoside.     

Glycosides of marine invertebrates. XV. A new triterpene glycoside — Holothurin A1 — From Caribbean holothurians of the family Holothuriidae

A glycoside, holothurin A₁ has been isolated from the polar glyosidic fractions of the holothuriansH. floridana andH. grisea. The complete structure of the glycoside has been established; it is: 3β-[0-(3-0-methyl-β-D-glucopyranosyl)-(1 → 3)-0-β-D-glucopyranosyl-(1 → 4)-0-β-D-quinovopyranosyl-(1 → 2)-(4-sulfato-β-D-xylopyranosyl)oxy]holosta-9(11)-ene-12α,17α,22ξ-triol. Details of the IR and¹H and¹³C NMR spectra of the compounds obtained are given.