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先进的微生物芯片检测系统及其应用 总被引:1,自引:1,他引:0
发展了一种先进的微生物芯片检测方法,并研制用于芯片检测的新型数字化成像扫描检测系统。采用激光诱导荧光的检测原理设计一种新颖的CCD数字化成像扫描检测系统结构,荧光信号采集端的数值孔径NA=0.72,工作距离3.22 mm,系统检测灵敏度小于每平方微米1个荧光分子。以微生物大肠杆菌和黄单胞菌检测为例,设计基因芯片,并应用所研制的芯片检测系统实现了微生物的正确鉴定,提供了一种高效的食品安全检测整体解决方法。实验结果表明两种微生物的芯片检测实验结果稳定可靠,与国外共焦扫描仪检测的结果完全一致。 相似文献
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针对当前的大区域内火情监控以人工为主,实时性较差,报警存在延时的问题;在需求分析的基础上,设计并实现了一种基于嵌入式与GPRS技术的大区域火情监控系统,硬件平台以嵌入式 S3C2410 芯片配合温度传感器LM75A以及相关外围电路,采集处理传感温度信息,利用GPRS网络的大范围数据通信能力传递各种火情信息,软件采用了分层的设计思想,将整个系统的软件设计分为用户应用层、网络集成层、硬件驱动层3个层次结构进行设计,利用SMS的方式进行火灾报警,避免了人工检测时主观强,实时性差的弊端;系统经过大量的实际数据测试证明,误差率基本能够保持在15%以内,比传统算法,报警准确率提高了27.4%,大区域控制范围在1平方公里,报警性能良好,具有很强的实际应用价值。 相似文献
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《中国光学与应用光学文摘》2005,(4)
TN253 2005042833 微流体光纤芯片的研究进展=Research development of microfluidic fiber chip[刊,中]/孔令志(陆军航空兵学院基础部,北京(101114)),张江涛…//光电技术应用,-2005, 20(1),-33-37 微流体光纤芯片是一种把光纤植入到芯片中以方便检测的新型生物芯片,它具有体积小、试剂消耗少、处理速度快、灵敏度高、可实现高度集成等特点。结合目前光纤芯片的发展状况,综述了两种类型光纤芯片的制作方法, 介绍了每种芯片的检测原理、结构及其分类,分析了每种芯片的优点与不足,并探讨了其发展趋势。图7参13(严寒) 相似文献
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基于当前的COB封装LED芯片,分析了芯片的热阻模型,推导出发光结在理想温度下工作时的基板温度。针对大功率LED存在的散热问题,基于课题组双进双出射流冲击水冷散热系统,设计了一种模糊控制器,选取温度变化和温度变化率为控制输入量,并对各控制输入量的范围设定进行了说明。根据设计的控制器进行程序编写,下载到控制芯片中进行实际验证,在20℃环境温度下,芯片基板温度最终维持在35.5~36.5℃之间,保证了灯具正常、稳定工作,为大功率LED散热系统提供了一种控制器设计方案,具有一定的实际意义。 相似文献
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Alignment-free optical modules using solder-bump-bonding technique for free-space optical interconnections 总被引:1,自引:0,他引:1
We propose alignment-free optical modules using a solder-bump-bonding technique for constructing free-space optical interconnection
systems without a special alignment procedure. Bonding pads for mounting an optoelectronic device chip are fabricated by exposing
a photosensitive resin film to light traveling through the optical system of the module so that the image positions of the
bonding pads on both image planes of the optical interconnection system are aligned with each other. A device chip is mounted
by solder-bump bonding and is set at a proper position by the surface tension of molten solder. The effectiveness of the technique
is verified by constructing alignment-free optical modules. 相似文献
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激光光束技术运用的越来越广泛,包括光通信技术,激光测距技术,激光瞄准技术等,其中光通信技术范围最广;在光通信过程中,需要面对光束发射端与接收端中心对齐的问题,增加了操作的难度;针对光通信激光光束对准难的特点,研究并设计了一套基于FPGA的激光光束对准系统,利用在FPGA芯片上设计软硬件速度快、稳定可靠、研发周期短等特点;整个系统以FPGA芯片为核心,辅以操作电路、自适应算法;实验表明, 该系统较好地符合了光束对准的要求。 相似文献
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G. R. Brady A. R. Ellis D. L. Moehring D. Stick C. Highstrete K. M. Fortier M. G. Blain R. A. Haltli A. A. Cruz-Cabrera R. D. Briggs J. R. Wendt T. R. Carter S. Samora S. A. Kemme 《Applied physics. B, Lasers and optics》2011,103(4):801-808
We have successfully demonstrated an integrated optical system for collecting the fluorescence from a trapped ion. The system, consisting of an array of transmissive, dielectric micro-optics and an optical fiber array, has been intimately incorporated into the ion-trapping chip without negatively impacting trapping performance. Epoxies, vacuum feedthrough, and optical component materials were carefully chosen so that they did not degrade the vacuum environment, and we have demonstrated light detection as well as ion trapping and shuttling behavior comparable to trapping chips without integrated optics, with no modification to the control voltages of the trapping chip. 相似文献
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为实现微流控芯片上微液滴的检测与计数,设计了光纤式检测与计数单元,使用TracePro软件进行建模仿真以便为检测信号处理提供依据。根据液滴通过检测区域时引起的光强变化来实现计数,分析了照明光束准直性、液滴尺寸、液滴相对溶液折射率以及接收光纤相距芯片距离对光强变化的影响。仿真实验结果表明,照明光束准直性越差,液滴半径越大,相对溶液折射率越低,接收光纤距离越近,相对光强变化越明显,并且液滴大小决定着光强变化曲线中是否会出现双波谷现象,液滴半径小于13 μm时,液滴检测信号为明显的单波谷,半径大于17 μm时,液滴信号为明显双波谷。根据仿真结果提出了检测信号的处理方法,表明该单元可以实现微流控芯片上微液滴的检测与计数功能。 相似文献
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The impact of fiber polarization mode dispersion (PMD) on the bit error rate (BER) performance of a direct sequence optical code-division multiple-access system is analyzed by the split-step Fourier method based on the coupled nonlinear Schrödinger equation, the three-dimensional Poincare sphere theory and the Jones matrix method. When the incident pulse's width is bigness than the chip duration, which causes spreading and overlapping of chips and degrades system performance due to increased interchip interference and reduced received optical power conduce cannot decoding or error decoding. When the incident pulse's width is less than the chip duration, good encoding/decoding performance can be achieved. 相似文献
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We present a new combination of a fluorescent film deposited onto a chip and a new kind of low-cost optical fluorescence probe. The probe consists of an optical fiber which guides the excitation beam to the chip and a second one which collects the fluorescence light toward a spectrometer slotted into a PC. The resulting data are then processed to extract the pertinent information. This system is designed for the detection of DNA but, at present, we have achieved the detection of functionalized lipidic vesicles and studied the photobleaching process of such films. 相似文献
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Kuan Chou Hou Po Chien Chou Stone Cheng Yue Jheng Lin Yi Chiu Jin Chern Chiou 《Optical Review》2011,18(1):60-65
In this investigation, a small-form-factor (SFF) pickup head with a holographic optical element (HOE) is fabricated. The system
employs a finite-conjugate object lens to focus a light beam. A holographic optical element is used to simplify the optical
configuration. It provides a better means of alignment of fabrication and reduces the size of system relative to reflective
light route. Micro prisms are fastened with HOE and a silicon substrate, laser diode and photodiode are integrated into the
optical system. The pickup head system based on discrete components and a flip chip bonder with highly accurate alignment
was to integrate it. The micro holographic optical pickup head is fabricated and tested. Experimental results including the
spot diameter and the focusing error signal (FES), demonstrate that the optical system is a feasible. 相似文献
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提出了一种新型的具有灵活扩育能力的分块式纵横制光互连网络体系结构,并给出了该网络在最大扩充时光学子系统的物理实现及相应的一些实验结果。该体系结构中可采用自电光效应器件作为高速光调制器。采用在单块GaAs基片上集成的场效应晶体管-自电光效应器件作为逻辑光开关器件。 相似文献