IBDP化学与AP化学对比分析

为了给计划开设国际课程的中国学校提供国际课程实施经验,从一个实践者的角度,对IBDP化学与AP化学在评估方式、课程内容以及所引发的教学方式等方面进行了对比分析,结果指出IBDP化学是在IB课程整体框架下实施的,课程实施者需要有先进的教育、教学理念做支撑,AP化学是独立的学科,由于时间的限制、评估方式的因素,AP化学是一种内容驱动的教学。     

"演示-评课-实验"教学模式在实验课程教学中的应用与优化策略——以高师化学专业教学论实验课程为例

"学生演示-集体评课-全班实验"三环节教学模式是高师教学论实验课程的主要形式,我们对化学专业教学论实验课程教学现状进行了教学观察和调研,从教学内容的选择、教学组织形式、教学管理形式、课程评价方式等方面进行优化,取得明显的教学效果。这对促进高师院校的化学实验教学改革、培养创新型实验教学能力的师范生有一定的参考价值。     

高师"化学教学论实验"教学评价体系的建立与实践

评价是课程的重要组成部分。目前高师“化学教学论实验”课程教学评价的弊端有:(1)评价功能窄化;(2)评价内容面窄;(3)评价方法单一;(4)评价主体惟一。这种现状很难保证课程教学目标的实现,也与基础教育新课程的化学实验教学评价理念不相适应,因此,迫切需要建立一个比较全面、客观、科学合理的高师“化学教学论实验”课程教学评价体系。该门课程是一门学生显性的、实践的教学活动课程,其教学评价体系的建立应从评价内容全面性、评价方式(评价方法与评价主体)多样化、评价类别合理性和评价操作简约化4方面综合考虑,并进行了实践验证。     

制药工程专业化学课程改革的探索与实践

化学课程是制药工程专业的必修课程,教学中存在部分理论内容交叉重叠、实验课程相互独立、内容多学时少、教学模式与教学评价体系陈旧等问题。介绍了临沂大学制药工程专业在化学课程改革方面的一些探索与实践,包括对理论课程体系和实验课程体系进行整合和优化、开设化学综合性实验和创新性实验、改进教学方法和进行创新课堂建设、推进化学课程考试和考核改革等,以期为制药工程专业化学课程教学改革提供一些思路和借鉴。     

高师“中学化学实验教学技能训练”课程教学现状调查与分析*

实验教学能力是化学教师专业发展的重要标志。“中学化学实验教学技能训练”课程是化学师范生必修的综合性实验教学训练课程,对化学师范生实验教学技能的培养有着至关重要的作用。研究从“中学化学实验教学技能训练”课程的总体评价、学习态度、教学方式和评价方式以及学习困难等方面对化学师范生进行了调查分析。针对发现的问题,提出统筹课程设置、明确课程价值、建立学习共同体、加强实验思维训练等教学建议。     

追求卓越 激发潜能——AP化学课程“电解”课堂实录与评析

通过展示国内开设的AP化学课程中"电解"的课堂实录,体现其"追求卓越,激发潜能"的课程理念,并从实验方法创新、化学探究能力培养、先修课程开发等3个方面进行反思并得出启示。     

美国新AP化学考试特点分析

通过对改革后AP化学考试的形式、时间以及2014-2016年的AP化学试题进行分析,总结出新版AP化学考试的特点：增加简答题中实验题的数量,考查学生“科学实践”的能力;加强对图表的认知和理解能力的考查等。并得出对我国高中化学教学和高考的几点思考与启示。     

基于美国AP化学精编实验开发我国高中化学实验

基于AP（美国大学预修课程）化学实验教学和国内普通高中化学实验教学的实践,对比2者的课程标准,并以具体实验“未知化合物的成分定性分析（固体）”为案例,剖析2者的相似点与不同点,为一线教学的化学教师和国内未来高中化学的教学提供一些参考。     

成长记录袋在"中学化学教学设计论"教学评价中的应用研究.

"中学化学教学设计论"是我们主动适应新一轮基础教育课程改革、构建化学教学论课程体系之重要模块,成长记录袋评价是落实新的评价观的有效形式,也是对师范生进行评价的新方式.结合"中学化学教学设计论"教学评价实践,介绍了化学教学论课程模块体系中运用成长记录袋评价法进行评价的具体作法.     

PBL-TBL-CBL教学法在医学基础化学课程中的应用

选取医学基础化学课程中的2个章节,组织PBL-TBL-CBL组和LBL组进行教学实验,通过成绩考核、教师评价和问卷调查进行教学效果评价,探讨PBL-TBL-CBL整合模式在医学基础化学课程中理论和实验教学上的应用。通过对比分析,证实PBL-TBL-CBL整合模式教学可以充分调动学生的积极主动性,增强自学和团队合作能力,提高实验操作技能,准确掌握教学大纲要求的知识点,提升学生对化学学习的乐趣和自信。建议对基础化学的部分章节采用PBL-TBL-CBL整合模式教学,同时结合LBL传统教学共同来完成大纲要求的教学任务。     

二氧化碳和丙烯直接合成甲基丙烯酸的NiPMo/TiO2催化剂的研究

用溶胶-凝胶法以磷钼酸(MPA)的镍盐溶液水解钛酸四丁酯制备了NiPMo/TiO2催化剂.使用ICP、 XRD、 TG-DTA、 IR、 TPD-MS和微反应技术研究了催化剂的化学组成、热稳定性、化学吸附性质和催化反应性能.杂多钼酸盐与TiO2通过O2-在TiO2表面发生了键合.在623 K下,杂多阴离子仍保持原有的Keggin结构.CO2在Lewis酸位Ni(Ⅱ)和Lewis碱位Ni-O-Mo的桥氧协同作用下生成CO2卧式吸附态Ni(Ⅱ)←O-(CO)←(O--Ni).丙烯有多种吸附态在催化剂上吸附.在563 K、 1 MPa和空速1500 h-1的反应条件下,丙烯的摩尔转化率为3.2%,产物MAA选择性为95%.     

Toward new camptothecins. Part 6: Synthesis of crucial ketones and their use in Friedländer reaction

In the context of the preparation of camptothecin and luotonin A analogs, the synthesis of some key keto-precursors and their use in Friedländer condensation are described. This paper also focuses on the stability of these keto intermediates and emphasizes the major differences between indolizinones and pyrroloquinazolinones series. Noteworthy is also the report of some original structures isolated as by-products of some experiments.     

CoFe2O4自形成磁性液体场致结构化对磁化的影响

The Langevin paramagnetic theory can’t describe the relation between magnetization of ferrofluids and applied magnetic field. The structuralization of ferrofluids, which is considered the main influence factor of the magnetization, is regarded. The part of magnetization works is deposited when the structure is forming. This action influences the magnetization of ferrofluids directly or indirectly. On the base of the “compressing” model, the Langevin function that usually describes the magnetization of ferrofluid is modified, and a well-fitted curve is obtained. An equation of the relation between the equivalent volume fraction after being “compressed” and the intensity of magnetic field is discovered, which approximately describes the process of magnetization. The relation between the approximate initial susceptibility and the volume fraction can be obtained from modified formula.     

Highly regioselective Buchwald–Hartwig amination at C-2 of 2,4-dichloropyridine enabling a novel approach to 2,4-bisanilinopyridine (BAPyd) libraries

The highly regioselective Buchwald–Hartwig amination at C-2 of the cheap and readily accessible reagent, 2,4-dichloropyridine with a range of anilines and heterocyclic amines is described. This new methodology is robust and provides a facile access to 4-chloro-N-phenylpyridin-2-amines on 0.25 mol scale. These intermediates undergo a further Buchwald–Hartwig amination at higher temperature to enable rapid exploration of the chemical space at C-4 and to provide a library of 2,4-bisaminopyridines.     

KMnO4-mediated oxidative CN bond cleavage of tertiary amines: Synthesis of amides and sulfonamides

KMnO₄-mediated oxidative CN bond cleavage of tertiary amines producing secondary amine was introduced, which was trapped by electrophiles (acyl chloride and sulfonyl chloride) to form amides and sulfonamides. The reaction could take place at mild condition, tolerating a wide range of function groups and affording products in moderate to excellent yields.     

Chemistry of heterocyclic compounds at the A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, over 50 years (Review)

The review contains a concise historical account and information on the most significant researches undertaken by the staff at the A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences on the Chemistry of Heterocyclic Compounds. Dedicated to Academician of the Russian Academy of Sciences B. A. Trofimov on his 70th jubilee. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1443–1502, October, 2008.     

Sulfur-directed metal-free and regiospecific methyl C(sp3)–H imidation of thioanisoles

Regiospecific and direct imidation of the methyl C(sp³)–H bond of thioanisoles is realized under mild and metal-free conditions with N-fluorobis(benzenesulfonyl)imide as an oxidant and nitrogen source. Proposed mechanism suggests that thionium ion intermediates and a Pummerer-type reaction are involved. The imidation has advantages such as high step-economy, excellent functionality tolerance, and regiospecificity, giving structurally diverse imidation products.     

Selective syntheses of 2H-1,3-oxazines and 1H-pyrrol-3(2H)-ones via temperature-dependent Rh(II)-carbenoid-mediated 2H-azirine-ring expansion

The Rh(II)-catalyzed reaction of 2-carbonyl-substituted 2H-azirines with ethyl 2-cyano-2-diazoacetate or 2-diazo-3,3,3-trifluoropropionate provides an easy access to 2H-1,3-oxazines and 1H-pyrrol-3(2H)-ones. These compounds can be selectively prepared from the same starting material using temperature as the only varied parameter. The 2-azabuta-1,3-diene intermediate, a common precursor for both heterocyclic products, isomerizes into 2H-1,3-oxazine under kinetic control, while 1H-pyrrol-3(2H)-one is the sole product of the reaction at elevated temperatures. According to DFT-calculations a one-atom oxazine ring contraction involving ring-opening to a 2-azabuta-1,3-diene intermediate, followed by a 1,5- and 1,2-prototropic shift leads to the consecutive formation of imidoylketene and azomethine ylide, which then further undergo cyclization to the pyrrole derivative.     

Synthesis of 1-benzyloxypyrazin-2(1H)-one derivatives

Different approaches for the synthesis of 1-benzyloxypyrazin-2(1H)-one derivatives from simple amino acids have been investigated. A library of 33 precursors for the preparation of N-hydroxy pyrazinones was obtained in moderate to good yields.