A new caffeic ester from Incarvillea mairei var. granditlora （Wehrhahn） Grierson

A new cafferic ester, （＋）-2-（1-hydroxyl-4-oxocyclohexyl） ethyl caffeate, was isolated from the 80% ethanol extract of the whole plants of Incarvillea mairei var. granditlora （Wehrhahn） Grierson. The structure of the compound was established by spectroscopic methods.     

Three New Monoterpene Glucosides from Lamium amplexicaule

Three new monoterpene glucosides, lamiuamplexosides A–C ( 1 – 3 ), along with thirteen known glucosides, were isolated from the whole plant of Lamium amplexicaule L. The structures of 1 – 3 were elucidated on the basis of spectroscopic, chemical, and physicochemical evidence.     

Three New Hasubanan Alkaloids from Stephania hernandifolia (Willd.) Walp.

Three new hasubanan alkaloids, hernsubanines A–C ( 1 – 3 , resp.), were isolated from the whole plants of Stephania hernandifolia. Their structures were elucidated on the basis of physical and spectroscopic data. In in vitro tests for cytotoxic activity against two human cancer cell lines, A 549 and K 562, compound 1 did not exhibit any cytotoxicity.     

New Diterpene Alkaloids from Aconitum sungpanense var. leucanthum

Five new C₁₉ diterpene alkaloids, leucanthumsines A ( 1 ), B ( 2 ), C ( 3 ), D ( 4 ), and E ( 5 ), were isolated from the Chinese medicinal herb Aconitum sungpanense var. leucanthum, together with the known C₁₉ diterpene alkaloids pseudaconine, neoline, 1‐O‐methyldelphisine, crassicaudine, chasmanine, talatisamine, indaconitine, ezochansmanine, and leueantine D. The structures of these new alkaloids were elucidated by HR‐MS and advanced NMR methods, including ¹H‐ and ¹³C‐NMR (DEPT), ¹H,¹H‐COSY, HMQC, and HMBC experiments.     

Two Novel Monoterpene Alkaloid Dimers from Incarvillea arguta

Two novel monoterpene alkaloid dimers, named argutanes A and B ( 1 and 2 , resp.), together with the known alkaloid boschniakine ( 3 ), were isolated from the roots of Incarvillea arguta. The structures were elucidated on the basis of 1D‐ and 2D‐NMR, as well as HR‐ESI‐MS data.     

Three New Sesquiterpene Pyridine Alkaloids from Euonymus fortunei

Three new macrocyclic β‐dihydroagarofuran‐type sesquiterpene pyridine alkaloids, fortuneines A ( 1 ), B ( 2 ), and C ( 3 ), together with the four known alkaloids wilfornine E ( 4 ), aquifoliunine E‐I ( 5 ), euoverrine B ( 6 ), and euojaponine I ( 7 ), were isolated from the aerial parts of Euonymus fortunei. Their structures were elucidated by spectroscopic methods, including HR‐ESI‐MS, ¹H‐ and ¹³C‐NMR, DEPT, ¹H,¹H‐COSY, HSQC, HMBC, and ROESY. This is the first isolation of the above sesquiterpene pyridine alkaloids from this plant, except for compound 6 .     

Evollionines A–C,Three New Alkaloids Isolated from the Fruits of Evodia rutaecarpa

A phytochemical study of the CHCl₃ extract of the dried unripe fruits of Evodia rutaecarpa (Juss. ) Benth. (Rutaceae) resulted in the isolation of three new alkaloids, evollionines A–C ( 1 – 3 , resp.), together with two known compounds, evodianinine and wuzhuyumide I. The structures of the new compounds were elucidated on the basis of detailed spectroscopic evidence and confirmed in the case of compound 1 by single‐crystal X‐ray analysis.     

Three New C19‐Diterpenoid Alkaloids from Aconitum transsectum

Three new C₁₉‐diterpenoid alkaloids, named aconitramines A ( 1 ), B ( 2 ), and C ( 3 ), were isolated from Aconitum transsectum. By UV, IR, 1D‐ and 2D‐NMR, and MS analyses, their structures were elucidated as 18‐methoxyvilmoraconitine, 18‐demethoxydolichotine A, and 18‐demethoxydolichotine B. Compound 1 is the second known C₁₉‐diterpenoid alkaloid with a three‐membered ring formed by C(8), C(9), and C(10).     

New Diterpenoid Alkaloids from Aconitum liangshanicum

One new C₁₉‐diterpenoid alkaloid, named liangshantine ( 1 ), and three new C₂₀‐diterpenoid alkaloids, liangshansines A–C ( 2 – 4 , resp.), as well as eight known compounds, were isolated from the roots of Aconitum liangshanicum. The structures of these new alkaloids were elucidated by spectroscopic methods.     

Three New Alkaloids from the Traditional Chinese Medicine ChanSu

Three new alkaloids, named bufoserotonins A–C ( 1 – 3 ), were isolated from the traditional Chinese medicine ChanSu. Their structures were elucidated on the basis of spectroscopic analysis, especially of 2D‐NMR data.     

Three New C19‐Diterpenoid Alkaloids from Aconitum hemsleyanum var. circinatum

Further phytochemical investigation of the roots of Aconitum hemsleyanum var. circinatum resulted in the isolation of three new aconitine‐type C₁₉‐diterpenoid alkaloids, hemsleyanines E–G ( 1 – 3 , resp.). The structures of these new alkaloids were elucidated on the basis of spectral data including 2D‐NMR.     

New Guaipyridine Sesquiterpene Alkaloids from Artemisia rupestris L.

Three new guaipyridine sesquiterpene alkaloids, rupestine A, B, C ( 1 – 3 , resp.), and the new nor‐sesquiterpne alkaloid rupestine D ( 4 ) were obtained from the flowers of Artemisia rupestris L. Their structures were elucidated on the basis of sepectroscopic data and by comparison with those of the related compounds reported in the literature. In addition, the absolute configurations of 2 and 4 were determined by single‐crystal X‐ray diffraction analyses.     

Bis‐Diterpenoid Alkaloids from Aconitum tanguticum var. trichocarpum

Phytochemical investigation of the whole herbs of Aconitum tanguticum (Maxim .) Stapf var. trichocarpum Hand.‐Mazz . led to the isolation of one heteratisine‐hetidine‐type bis‐diterpenoid alkaloid, trichocarpidine ( 1 ), three hetidine‐hetisine type bis‐diterpenoid alkaloids, trichocarpinine A–C ( 2 – 4 , resp.), together with nine known compounds. Their structures were elucidated by spectroscopic analyses.     

Diterpenoid Alkaloids from Delphinium tatsienense

Three new C₂₀‐diterpenoid alkaloids, along with twenty‐two known alkaloids, were isolated from the whole herbs of Delphinium tatsienense. The new alkaloids include a vakognavine‐type C₂₀‐diterpenoid alkaloid, designated as tatsienenseine A ( 1 ), and two hetisine‐type C₂₀‐diterpenoid alkaloids, designated as tatsienenseines B ( 2 ) and C ( 3 ). Their structures were elucidated by IR, HR‐ESI‐MS, 1D‐ and 2D‐NMR analyses.     

A Unique Indolo‐[1,7]naphthyridine Alkaloid from Incarvillea mairei var. grandiflora (Wehrh.) Grierson

A novel alkaloid with a unique indolo‐[1,7]naphthyridine nucleus, incargranine B, was isolated from the whole plant of Incarvillea mairei var. grandiflora (Wehrh.) Grierson . Its structure was determined by means of spectroscopic methods.     

Diterpenoid Alkaloids from Delphinium yunnanense

Three new diterpenoid alkaloids, along with eleven known alkaloids, were isolated from the whole herbs of Delphinium yunnanense. The new alkaloids include a rearranged‐type C₁₉‐diterpenoid alkaloid, named yunnanenseine A ( 1 ), and two hetisine‐type C₂₀‐diterpenoid alkaloids, named yunnanenseine B and C ( 2 and 3 , resp.). Their structures were elucidated by detailed NMR‐spectroscopic studies.     

Five New C19‐Diterpenoid Alkaloids from Aconitum hemsleyanum

Five new C₁₉‐diterpenoid alkaloids, named hemsleyaconitines A–E ( 1 – 5 , resp.), were isolated from Aconitum hemsleyanum Pritz. By UV, IR, MS, 1D‐ and 2D‐NMR analyses, their structures were elucidated as 18‐dehydroxygeniculatine D ( 1 ), 6‐hydroxy‐14‐O‐veratroylneoline ( 2 ), 14‐O‐acetyl‐8‐ethoxysachaconitine ( 3 ), 18‐veratroylkaracoline ( 4 ) and 8‐O‐ethylaustroconitine B ( 5 ).     

Three New Paeonidanin‐Type Monoterpene Glycosides from Paeonia suffruticosa Andr.

Three new paeonidanin‐type monoterpene glycosides, named suffrupaeonidanins A–C, were isolated as minor components from the root cortex of Paeonia suffruticosa Andr. Their structures were elucidated by a combination of 1D‐ and 2D‐NMR, and mass spectral techniques.