共查询到20条相似文献,搜索用时 12 毫秒
1.
E. V. Vlasova A. A. Aleksandrov M. M. El’chaninov 《Russian Journal of Applied Chemistry》2010,83(6):1027-1031
2-Phenyl-5-(2-furyl)- and 2-phenyl-5-(2-thienyl)imidazoles were synthesized by condensation of 2-furoylmethyl and 2-thenoylmethyl
acetates with benzaldehyde under the conditions of Weidenhagen reaction. The products were converted to N-methyl derivatives in the KOH-acetone system. The electrophilic substitution reactions of the products (acylation, bromination,
nitration, sulfonation, hydroxymethylation) were studied. 相似文献
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Conclusions The synthesis of some nuclear-substituted derivatives of 1-phenyl-1-methyl-1-silacyclobutane by the reaction of 1-methyl-1-chloro-1-silacyclobutane with the appropriate arylmagnesium bromides was described.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 7, pp. 1686–1688, July, 1978. 相似文献
4.
Alfred Schmidpeter Franz Steinmüller Konstantin Karaghiosoff 《Heteroatom Chemistry》1994,5(4):385-390
The triazaphosphole 1 adds sulfur along with HCl or H2S to yield, respectively, the dihydrotriazaphosphole thiochloride 4 and sesquisulfide 5 (two diastereomers). In pyridine solution, 1 adds sulfur alone to yield the trimer of a triazaphosphole monosulfide 7 . Its central cyclotriphosphazane trisulfide ring has a trans structure and a boat conformation. 相似文献
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1-Phenacyl-5-methyl-4-phenyl-2-phenacylidene-1,2-dihydropyridine was obtained, and its cyclization to substituted indolizines was examined. 相似文献
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Simple methods for the synthesis of 3-aryl-6-methyl-2-pyrones and 3-aryl-5-carbalkoxy-6-methyl-2-pyrones by the reaction of ethyl -formylarylacetates with acetone and acetoacetic acid esters, respectively, are proposed. Some electrophilic substitution reactions of 6-methyl-3-phenyl-2-pyrone and 5-carbethoxy-6-methyl-3-phenyl-2-pyrone were studied.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1477–1480, November, 1985. 相似文献
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The synthesis of 1,4-dihydro-4-methyl-1-phenyl-5H-1,3,4-benzotriazepin-5-one ( 4a ) and its 8-chloro analog ( 4b ) is described. Attempted synthesis of the 2-methyl analog of 4a from 2-(phenylamino)benzoic acid 1-methylhydrazide ( 10 ) and triethyl orthoaeetate led only to the Schiff base intermediate, 2-(phenylamino)benzoic acid 2-(1-ethoxyethylidene)-1-methylhydrazide ( 11 ). Cyclization of 11 was attempted unsuccessfully with a variety of reagents. The intere?ting reaction products from the treatment of 11 with trifluoroacetic acid are described. 相似文献
8.
Asahara M Katayama T Tohda Y Nishiwaki N Ariga M 《Chemical & pharmaceutical bulletin》2004,52(11):1334-1338
Unnatural 1-methyl-2-quinolone derivatives were synthesized by regioselective C-C bond formation. When 1-methyl-3,6,8-trinitro-2-quinolone (TNQ) was treated with enamines, nucleophilic addition readily occurred at the 4-position, and succeeding hydrolysis of enamine moiety followed by elimination of nitrous acid furnished 4-acylmethyl-1-methyl-6,8-dinitro-2-quinolones. The same products could be prepared by the reaction of TNQ with ketones in the presence of triethylamine. The present reaction enabled the introduction of various kinds of acylmethyl groups substituted with alkyl, aryl or hetaryl groups. 相似文献
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Summary A packing procedure was adopted for capillary electrochromatography (CEC) that produces capillary columns with high separation
efficiencies. The columns were fully packed, 50 cm long, with UV detection being performed through the packed section 30 cm
from the inlet end. The CEC experiments were run at ambient pressure, with no additional pressure applied to the ends of the
column. The stationary phase (octadecyl silica (ODS), 5 μm) promoted a high velocity electroosmotic flow (EOF), enabling rapid
and efficient separation of a hydrocarbon test mixture. Some 1-phenyl-3-methyl-5-pyrazolone (PMP) derivatives of mono- and
disaccharides were baseline separated, using a 5 mM NaH2PO4 in 80% acetonitrile and 20% water (v/v) buffer solution. CEC shows promise for future applications in carbohydrate analysis.
Presented at Balaton Symposium on High Performance Separation Methods, Siófok, Hungary, September 1–3, 1999 相似文献
11.
A. B. Zolotoi Yu. I. Él'natanov I. I. Chervin S. V. Konovalikhin O. A. D'yachenko L. O. Atovmyan R. G. Kostyanovskii 《Chemistry of Heterocyclic Compounds》1988,24(7):746-750
X-ray diffraction and NMR spectral examination have shown that 1-phenyl-3-methyl-2-pyrazolin-5-one reacts with methyl acrylate in methanol to give spiro[(1-phenyl-3-methyl-2-pyrazolin-5-one)-4,5-butyrolactone]. The conformation has been shown to be the same in the crystal and in solution, the pyrazoline ring has been found to be nonplanar, the reasons for the acoplanarity established, stabilizing and destabilizing interactions studied, and the orientation of the phenyl substituent relative to the pyrazolin-5-one ring determined.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 909–913, July, 1988. 相似文献
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Z. G. Aliev A. N. O. L. Maslivets Yu. N. Bannikova L. O. Atovmyan 《Journal of Structural Chemistry》2003,44(4):707-710
1-Benzyl-4-benzoyl-5-phenyl-2,3-dihydro-2,3-pyrroledione reacts with ketene diethylacetal, forming 1-benzyl-4-benzoyl-3-hydroxy-5-phenyl-5-ethoxycarbonylmethyl-2,5-dihydro-2-pyrrolone, whose crystal and molecular structure was studied by XRD. 相似文献
13.
The Vilsmeier formylation of 2-phenyl- and 3-phenyl-5-hydroxybenzofuran derivatives was studied. It is shown that 2-phenyl-5-methoxybenzofuran is formylated in the 4 position, whereas 3-phenyl-5-methoxybenzofuran is formylated in the 2 position.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1023–1024, August, 1976. 相似文献
14.
Chikhalikar S Bhawe V Ghotekar B Jachak M Ghagare M 《The Journal of organic chemistry》2011,76(10):3829-3836
The nucleophilic vinylic substitution reaction of the aliphatic enaminone 3-dimethylamino-2-formyl acrylonitrile 1 with the nucleophiles malononitrile and ethyl cyanoacetate produced the two unusual reaction adducts 3a and 3b in good to moderate yield under milder reaction conditions. Upon reaction with aromatic amines, these adducts yielded enamines 4 and 5, which eventually cyclized in the presence of base to produce the novel pyridin-2(1H)-one derivatives 8 and 9. 相似文献
15.
Nitrosation of acrylophenone oxime or of methacrylophenone oxime with n-butyl nitrite in the presence of pyridine and copper(II) sulfate gives the copper complexes of the title compounds. The free 1-hydroxypyrazole 2 -oxides are isolated by treating the copper complexes with dilute sodium hydroxide, filtration, and acidification of the basic filtrates. The title compounds are the first examples of 1-hydroxypyrazole 2 -oxides in which the C3(5) ring position is unsubstituted. 相似文献
16.
Dmitriy A. Sibgatulin Dmitriy M. Volochnyuk Eduard B. Rusanov Alexander N. Chernega 《Journal of fluorine chemistry》2010,131(2):234-237
The reaction of a set of enamines with methyl trifluoropyruvate and its imine was investigated. As a result, a simple procedure for synthesis of trifluoromethylated 2-pyrrolidone and 2-pyrrolone derivatives has been developed. 相似文献
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By a combination of hydrolysis, decarboxylation, and methylation diethyl 1-methyl-3-hydroxy-5-phenylpyrrole-2,4-dicarboxylate was converted into 1-methyl-3-methoxy-5-phenyl-pyrrole-2,4-dicarboxylic acid (5) and into the isomeric compounds ethyl 1-methyl-2-phenyl-4-methoxypyrrole-3-carboxylate (4a) and ethyl 1-methyl-3-methoxy-5-phenylpyrrole-2-carboxylate (9a). 1-Methyl-2-phenyl-4-methoxypyrrole-3-carboxylic acid was synthesized both by the selective decarboxylation of 5 and by the hydrolysis of 4a. Hydrolysis of 9a, however, did not give the corresponding acid, but rather an oxidation product, 1-methyl-3-methoxy-5-hydroxy-5-phenyl-3-pyrrolin-2-onc (10a). Compound 10a was shown to arise from the air oxidation of the completely decarboxylated product, 1-methyl-2-phenyl-4-methoxypyrrole. Reduction of 9a with lithium aluminum hydride gave 1-methyl-3-methoxy-5-phenylpyrrole-2-methanol, which yielded 10a upon oxidation with silver oxide. 相似文献
19.
N. S. Prostakov L. M. Kirillova I. V. Klyavina P. I. Zakharov M. D. Kharlamova A. É. Aliev 《Chemistry of Heterocyclic Compounds》1990,26(3):350-356
The dichloride, diethylamide, and amide were obtained from -phenyldinicotinic acid. 2-Phenyl-3,5-diamino- and 3,5-dicyanopyridine were synthesized from the amide. 2-Phenyl-3,5-bis(5-phenyl-2-oxazolyl)pyridine and 2-phenyl-3-carboxy-5-(5-phenyl-2-oxazolyl)pyridine were obtained. The luminescence properties of the synthesized compounds were studied.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 405–411, March, 1990.The authors thank A. A. Ustenko and E. N. Smirnova for their assistance in calculation of the spectral data. 相似文献