Microwave-Assisted Synthesis of Six-Membered O-Heterocycles

The development of new strategies for synthesis of six-membered O-heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in oxygen-containing six-membered heterocyclic compounds synthesis is presented, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of six membered O-heterocycles.     

Microwave-Assisted Synthesis of Five-Membered O-Heterocycles

The development of new strategies for synthesis of five-membered O-heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in oxygen-containing five-membered heterocyclic compound synthesis is presented, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of five-membered O-heterocycles.     

Microwave-Assisted Synthesis of Seven- and Higher-Membered O-Heterocycles

The development of new strategies for synthesis of medium-sized O-heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in oxygen-containing seven- and higher-membered heterocyclic compounds synthesis is presented, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of O-heterocycles. The literature data are summarized based on the size of cycles.     

Microwave-Assisted Synthesis of Six-Membered S-Heterocycles

The development of new strategies for synthesis of six-membered S-heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in sulfur-containing six-membered heterocyclic compounds synthesis is presented, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of six-membered S-heterocycles.     

Polycyclic Six-Membered N-Heterocycles: Microwave-Assisted Synthesis

The development of new strategies for synthesis of polycyclic heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in nitrogen-containing six-membered polycyclic heterocyclic compounds synthesis is presented, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of N-heterocycles.     

Microwave-Assisted Synthesis of Fused Polycyclic Six-Membered N-Heterocycles

The development of new strategies for synthesis of fused polycyclic heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in nitrogen-containing six-membered fused polycyclic heterocyclic compounds synthesis is presented, focusing on the developments in the past 5 to 10 years. This contribution covers the literature concerning the total synthesis of fused polycyclic N-heterocycles.     

Review of Microwave-Assisted Synthesis of Benzo-Fused Six-Membered N,N-Heterocycles

The development of new strategies for synthesis of fused heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in nitrogen-containing benzo-fused six-membered heterocyclic compounds synthesis is presented, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of benzo-fused N,N-heterocycles.     

Microwave-Assisted Synthesis of Five-Membered O,N-Heterocycles

The development of new strategies for the synthesis of five-membered O,N-heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in oxygen- and nitrogen-containing five-membered heterocyclic compounds synthesis is presented, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of five-membered O,N-heterocycles.     

Microwave-Assisted Synthesis of Five-Membered O,N,N-Heterocycles

The development of new strategies for synthesis of five-membered O,N,N-heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in oxygen and two nitrogen atoms containing five-membered heterocyclic compounds synthesis is presented, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of five-membered O,N,N-heterocycles.     

Applications of Microwaves in the Synthesis of Polycyclic Six-Membered N,N-Heterocycles

The development of new strategies for the synthesis of polycyclic heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in the synthesis of six-membered polycyclic heterocyclic compounds containing two nitrogen atoms is presented, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of six-membered polycyclic N,N-heterocycles.     

Microwave-Assisted Synthesis of Seven-Membered S-Heterocycles

The development of new strategies for synthesis of medium-sized S-heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in sulfur-containing seven-membered heterocyclic compounds synthesis is presented, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of S-heterocycles. The literature data are summarized based on the size of cycles.     

Greener and Expeditious Synthesis of Fused Six-Membered N,N-Heterocycles Using Microwave Irradiation

The development of new strategies for the synthesis of fused heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in the synthesis of fused six-membered heterocyclic compounds containing two nitrogen atoms is presented, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of fused N,N-heterocycles.     

Advances in Microwave-Assisted Synthesis for Five-Membered N-Heterocycle Synthesis

The development of new strategies for the synthesis of small-sized heterocycles hasremained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in the synthesis of nitrogen-containing five-membered heterocyclic compounds is presented, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of N-heterocycles.     

Microwave-Assisted Synthesis: Fused Five-Membered N-Heterocycles

The development of new strategies for the synthesis of small-sized heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in nitrogen-containing fused five-membered heterocyclic compounds synthesis is presented, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of fused N-heterocycles.     

Microwave-Assisted Synthesis of Seven- and Higher-Membered N-Heterocycles

The development of new strategies for synthesis of medium-sized heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in the synthesis of nitrogen-containing seven- and higher membered heterocyclic compounds is presented, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of N-heterocycles. The literature data are summarized based on the size of cycles.     

Insight into Microwave-Assisted Synthesis of Benzo Derivatives of Five-Membered N,N-Heterocycles

The development of new strategies for the synthesis of small-sized heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in nitrogen-containing benzo derivatives of five-membered heterocyclic compounds synthesis is presented here, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of benzo derivatives of five-membered N,N-heterocycles.     

Recent Impact of Microwave-Assisted Synthesis on Benzo Derivatives of Five-Membered N-Heterocycles

The development of new strategies for the synthesis of small-sized heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation in nitrogen-containing benzo derivatives of five-membered heterocyclic compounds synthesis is presented here, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of benzo derivatives of five-membered N-heterocycles.     

Nitrogen-Containing Six-Membered Heterocycles: Solid-Phase Synthesis

Solid-phase organic synthesis is a rapidly expanding area of synthetic chemistry that is being widely exploited in the search for new medicinally important compounds using combinatorial techniques. In recent decades, a large number of reports related to solid-phase synthesis of heterocycles have appeared because of the wide variety of their biological activity. In this review, we report the important role of solid-phase synthesis in the synthesis of nitrogen containing six-membered ring heterocycles.     

微波辅助组合合成的研究进展

微波辅助组合合成技术是近年来发展起来的一种新的制备化合物库的组合化学技术, 它不仅可以克服传统固相组合合成技术以及液相组合合成技术无法提高产物收率的不足, 而且利用该技术所制得的化合物库中对应的是高纯度的单一化合物, 采用高通量筛选技术可以快速直接地确定高活性结构, 极大地提高了新药开发的效率. 主要就近年来微波辅助组合合成技术的研究进展情况进行介绍, 内容包括固相组合合成、基于聚合物支载的催化剂的组合合成、液相组合合成、氟相组合合成以及组合平行合成等.     

Synthesis of Five-Membered N,N,N- and N,N,N,N-Heterocyclic Compounds: Applications of Microwaves

The development of new strategies for the synthesis of small-sized heterocycles has remained a highly attractive but challenging proposition. An overview of the application of microwave irradiation to the synthesis of five-membered heterocyclic compounds containing three and four nitrogen atoms is presented, focusing on the developments in the past 5–10 years. This contribution covers the literature concerning the total synthesis of N,N,N- and N,N,N,N-heterocycles. The literature data are summarized based on the size and type of cycles.